Increased concanavalin A induced suppression in treated and untreated coeliac disease.

abstract：:Video endoscopic images were used to investigate whether gastroenterologists could agree on the definition of lesions within the stomach seen at endoscopy, with particular reference to those seen in patients taking non-steroidal anti-inflammatory drugs. Seven experienced endoscopists, unaware of the patients' clinical...

journal_title：Gut

authors： Hudson N,Everitt S,Hawkey CJ

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Experimental, clinical, and epidemiological studies have implicated mitogenic metabolites of arachidonic acid such as prostaglandin E(2) (PGE(2)) in colorectal carcinogenesis. Recently, cyclooxygenase 2 (COX-2) which catalyses the conversion of arachidonic acid to PGE(2), has displayed increased levels in hu...

journal_title：Gut

authors： Dimberg J,Samuelsson A,Hugander A,Söderkvist P

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Almost 4% of the population suffer from food allergy which is an adverse reaction to food with an underlying immunological mechanism. AIMS:To characterise one of the most frequent IgE defined food allergens, fish parvalbumin. METHODS:Tissue and subcellular distribution of carp parvalbumin was analysed by i...

journal_title：Gut

authors： Bugajska-Schretter A,Grote M,Vangelista L,Valent P,Sperr WR,Rumpold H,Pastore A,Reichelt R,Valenta R,Spitzauer S

更新日期：2000-05-01 00:00:00

abstract：:This experimental study was undertaken to follow the influence of phenobarbital on bile chemistry and gallstone formation. Phenobarbital (400 mg/kg/day) was administered to golden hamsters receiving a diet known to induce cholesterol gallstones. After a 28-day period none of the control animals had gallstones whereas ...

journal_title：Gut

authors： Lagarriga J,Bouchier IA

更新日期：1973-12-01 00:00:00

abstract：OBJECTIVE:Non-oxidative metabolism of ethanol (NOME) produces fatty acid ethyl esters (FAEEs) via carboxylester lipase (CEL) and other enzyme action implicated in mitochondrial injury and acute pancreatitis (AP). This study investigated the relative importance of oxidative and non-oxidative pathways in mitochondrial dy...

journal_title：Gut

authors： Huang W,Booth DM,Cane MC,Chvanov M,Javed MA,Elliott VL,Armstrong JA,Dingsdale H,Cash N,Li Y,Greenhalf W,Mukherjee R,Kaphalia BS,Jaffar M,Petersen OH,Tepikin AV,Sutton R,Criddle DN

更新日期：2014-08-01 00:00:00

abstract：:The highest prevalence rates of hepatitis C virus infection in the world have been recently reported among Egyptian blood donors and frequent recipients of transfusions and other blood products. This is the first report, however, demonstrating hepatitis C as the most frequent association with chronic liver disease in ...

journal_title：Gut

authors： Waked IA,Saleh SM,Moustafa MS,Raouf AA,Thomas DL,Strickland GT

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:Most colorectal cancer (CRC) screening programmes are nowadays based on faecal immunochemical testing (FIT). Eligible subjects often use oral anticoagulants (OACs) or non-steroidal anti-inflammatory drugs (NSAIDs), which could possibly stimulate bleeding from both benign and premalignant lesions in the colon....

journal_title：Gut

authors： Nieuwenburg SAV,Vuik FER,Kruip MJHA,Kuipers EJ,Spaander MCW

更新日期：2019-05-01 00:00:00

abstract：:Inflammatory mediators from intestinal mast cells may serve as initiators of acute and delayed inflammation. Mast cell histamine release was measured in 19 patients with inflammatory bowel diseases using gut mast cells from enzymatically dispersed endoscopic forceps biopsy specimens of macroscopically inflamed and nor...

journal_title：Gut

authors： Nolte H,Spjeldnaes N,Kruse A,Windelborg B

更新日期：1990-07-01 00:00:00

abstract：:There is no universally available laboratory test to diagnose bile acid diarrhoea (BAD). OBJECTIVE:To conduct a systematic review and meta-analysis to identify a biomarker for idiopathic BAD in patients with functional bowel disorder (FBD) with diarrhoea. DESIGN:We searched multiple databases through 15 May 2015. Da...

journal_title：Gut

authors： Valentin N,Camilleri M,Altayar O,Vijayvargiya P,Acosta A,Nelson AD,Murad MH

更新日期：2016-12-01 00:00:00

abstract：:In normal subjects the length of the functional anal sphincter has been compared with the extent of sensation to light touch in the anal canal. At rest, the sphincteric zone was the longer. On distension of the rectum, a decrease in pressure in the anal canal so shortened the functional sphincter that intrarectal pres...

journal_title：Gut

authors： Duthie HL,Bennett RC

更新日期：1963-06-01 00:00:00

abstract：OBJECTIVE:Chronic pancreatitis (CP) is an inflammatory disease with progressive fibrosis leading to exocrine and endocrine dysfunction. Currently, there are no approved effective therapies for CP. Stimulator of interferon genes (STING) signalling is a key innate immune sensor of DNA. In this study, we evaluated the rol...

journal_title：Gut

authors： Zhao Q,Manohar M,Wei Y,Pandol SJ,Habtezion A

更新日期：2019-10-01 00:00:00

abstract：:The absorption of short chain fatty acids by the human rectum in the absence of chloride has been studied using a dialysis bag technique. Absorption rates of sodium, water, and short chain fatty acids were unchanged on replacing chloride with sulphate. Final concentrations of bicarbonate were 35.4 +/- 3.4 mmol/l in th...

journal_title：Gut

authors： McNeil NI,Cummings JH,James WP

更新日期：1979-05-01 00:00:00

abstract：:The responses to deglutition of the lower oesophageal high pressure zone were studied in 13 healthy subjects. The recording assembly included three perfused pressure recording catheters, whose recording orifices were at the same axial level, and a more distally situated pH electrode. Relaxation and contraction progres...

journal_title：Gut

authors： Kaye MD,Showalter JP

更新日期：1972-05-01 00:00:00

abstract：OBJECTIVE:To investigate the molecular function of splicing factor SRSF6 in colorectal cancer (CRC) progression and discover candidate chemicals for cancer therapy through targeting SRSF6. DESIGN:We performed comprehensive analysis for the expression of SRSF6 in 311 CRC samples, The Cancer Genome Atlas and Gene Expres...

journal_title：Gut

authors： Wan L,Yu W,Shen E,Sun W,Liu Y,Kong J,Wu Y,Han F,Zhang L,Yu T,Zhou Y,Xie S,Xu E,Zhang H,Lai M

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:An increasing number of case reports indicate potential nephrotoxicity of 5-aminosalicylic acid (5-ASA), which shares similarities with the chemical structures of both phenacetin and acetylsalicylic acid. AIM:In a point prevalence study the occurrence of sensitive indices indicative of early kidney malfunct...

journal_title：Gut

authors： Schreiber S,Hämling J,Zehnter E,Howaldt S,Daerr W,Raedler A,Kruis W

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:This is a consensus developed by a group of expert endoscopists aiming to standardise the preparation, process and endoscopic procedural steps for diagnosis of early upper gastrointestinal (GI) cancers. METHOD:The Delphi method was used to develop consensus statements through identification of clinical ques...

journal_title：Gut

authors： Chiu PWY,Uedo N,Singh R,Gotoda T,Ng EKW,Yao K,Ang TL,Ho SH,Kikuchi D,Yao F,Pittayanon R,Goda K,Lau JYW,Tajiri H,Inoue H

更新日期：2019-02-01 00:00:00

abstract：:We report on clinical, nutritional, and hepatic histological findings in 50 non-selected obese subjects (mean overweight +74%; range +21-138%). The pathogenesis of the liver damage was assessed with the help of multidimensional analysis of a number of clinical variables. According to the severity of the hepatic lesion...

journal_title：Gut

authors： Braillon A,Capron JP,Hervé MA,Degott C,Quenum C

更新日期：1985-02-01 00:00:00

abstract：:This paper reports the association between severe, prolonged, watery diarrhoea and islet cell tumours of the pancreas. There appear to be significant differences between patients with these symptoms and those with the classical Zollinger-Ellison syndrome. ...

journal_title：Gut

authors： TELLING M,SMIDDY FG

更新日期：1961-03-01 00:00:00

abstract：:In 34 patients with fulminant hepatic failure, platelets, in addition to being reduced in numbers, were smaller than those of healthy controls. In keeping with this, capillary bleeding times were significantly longer than could be accounted for by reduction in numbers alone. In a small group of these patients use of c...

journal_title：Gut

authors： Weston MJ,Langley PG,Rubin MH,Hanid MA,Mellon P,Williams R

更新日期：1977-11-01 00:00:00

abstract：:Using immune electron microscopy, an attempt has been made to visualise viral particles in Crohn's disease tissue and faeces. No particles resembling viruses were observed, but in the absence of a specific antiserum a negative result does not exclude the presence of a virus, particularly if it is sparsely distributed....

journal_title：Gut

authors： Whorwell PJ,Baldwin RC,Wright R

更新日期：1976-09-01 00:00:00

abstract：OBJECTIVE:Tissue stem cells are central regulators of organ homoeostasis. We looked for a protein that is exclusively expressed and functionally involved in stem cell activity in rapidly proliferating isthmus stem cells in the stomach corpus. DESIGN:We uncovered the specific expression of Iqgap3 in proliferating isthm...

journal_title：Gut

authors： Matsuo J,Douchi D,Myint K,Mon NN,Yamamura A,Kohu K,Heng DL,Chen S,Mawan NA,Nuttonmanit N,Li Y,Srivastava S,Ho SWT,Lee NYS,Lee HK,Adachi M,Tamura A,Chen J,Yang H,Teh M,So JB,Yong WP,Tan P,Yeoh KG,Chuang LSH

更新日期：2020-12-08 00:00:00

abstract：:The radio-telemetering capsule (radio-pill) has been used to study the return of motility in the small bowel after vagotomy with a drainage procedure, gastric operations not involving vagotomy, and non-gastric operations. Small intestinal movements returned in about 10 hours after vagotomy, about four hours after the ...

journal_title：Gut

authors： ROSS B,WATSON BW,KAY AW

更新日期：1963-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Pancreatic cancer is among the most dismal of human malignancies. Current therapeutic strategies are virtually ineffective in controlling advanced, metastatic disease. Recent evidence suggests that the Hedgehog signalling pathway is aberrantly reactivated in the majority of pancreatic cancers, and t...

journal_title：Gut

authors： Feldmann G,Habbe N,Dhara S,Bisht S,Alvarez H,Fendrich V,Beaty R,Mullendore M,Karikari C,Bardeesy N,Ouellette MM,Yu W,Maitra A

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Hepatocellular carcinoma (HCC) is a heterogeneous tumour displaying a complex variety of genetic and epigenetic changes. In human cancers, aberrant post-transcriptional modifications, such as alternative splicing and RNA editing, may lead to tumour specific transcriptome diversity. DESIGN:By utilising large ...

journal_title：Gut

authors： Chan TH,Lin CH,Qi L,Fei J,Li Y,Yong KJ,Liu M,Song Y,Chow RK,Ng VH,Yuan YF,Tenen DG,Guan XY,Chen L

更新日期：2014-05-01 00:00:00

abstract：:Peptide histidine isoleucine, a 27 amino acid peptide with close amino acid sequence homology to vasoactive intestinal peptide and secretin, is distributed throughout the mammalian intestinal tract, where it has been localised to intramural neurones. An intestinal perfusion technique has been used to study the effect ...

journal_title：Gut

authors： Moriarty KJ,Hegarty JE,Tatemoto K,Mutt V,Christofides ND,Bloom SR,Wood JR

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:We previously described hepatitis reactivation in two carriers of the hepatitis C virus (HCV) genotype 2c. AIM:To assess the relationship between HCV genotypes and risk of hepatitis reactivation, we studied the course of aminotransferases in patients infected with the two relevant genotypes in Italy. PATIE...

journal_title：Gut

authors： Rumi MG,De Filippi F,La Vecchia C,Donato MF,Gallus S,Del Ninno E,Colombo M

更新日期：2005-03-01 00:00:00

abstract：:Distal duodenal biopsy specimens taken from 30 white, 35 Indian, and 20 Afro-Caribbean residents of West Birmingham during routine endoscopy for dyspepsia, were assessed by dissecting microscopy and morphometry. Finger-shaped villi were significantly less frequent in the Indian and Afro-Caribbean subjects than in the ...

journal_title：Gut

authors： Wood GM,Gearty JC,Cooper BT

更新日期：1991-03-01 00:00:00

abstract：:Training to contract the abdominal muscles effectively and to relax the pelvic floor during defecation straining helps some patients with severe constipation. Hitherto all such training has used a visible or audible signal of sphincter muscle activity as a biofeedback method to assist in relaxation. A randomised contr...

journal_title：Gut

authors： Koutsomanis D,Lennard-Jones JE,Roy AJ,Kamm MA

更新日期：1995-07-01 00:00:00

abstract：:Upper gastrointestinal function in response to a mixed nutrient meal was evaluated in hyperthyroid patients, both before and after therapy, and in healthy controls. Gastric secretion, gastric emptying, and pancreatic secretion were all normal and normally integrated postprandially in the hyperthyroid patients. Bile ac...

journal_title：Gut

authors： Miller LJ,Owyang C,Malagelada JR,Gorman CA,Go VL

更新日期：1980-08-01 00:00:00

abstract：:Both carbachol (10(-4)-10(-3) mol/l) and cholecystokinin octapeptide (CCK-8) (10(-8)-10(-6) mol/l) significantly stimulated the release of pepsinogen from rabbit gastric mucosa maintained in organ culture (213-216% and 143-261% of control, respectively, p less than 0.05-0.01). The secretion was not affected by removin...

journal_title：Gut

authors： Miyamoto T,Itoh M,Noguchi Y,Yokochi K

更新日期：1992-01-01 00:00:00