Studies on the effect of vagotomy on small intestinal motility using the radiotelemetering capsule.


:The radio-telemetering capsule (radio-pill) has been used to study the return of motility in the small bowel after vagotomy with a drainage procedure, gastric operations not involving vagotomy, and non-gastric operations. Small intestinal movements returned in about 10 hours after vagotomy, about four hours after the various gastric operations, and within one hour in those operations not involving handling of the viscera. The implications of these results are discussed in relation to the management of patients after gastric surgery.











Has Abstract


1963-03-01 00:00:00












  • Effect of dietary nucleotides on small intestinal repair after diarrhoea. Histological and ultrastructural changes.

    abstract::The effects of specific nutrients on intestinal maturation and repair after injury are practically unknown. The purpose of this work was to study the effects of dietary nucleotides on the repair of the intestinal mucosa after chronic diarrhoea induced by a lactose enriched diet in the weanling rat. One group of weanli...


    pub_type: 杂志文章


    authors: Bueno J,Torres M,Almendros A,Carmona R,Nuñez MC,Rios A,Gil A

    更新日期:1994-07-01 00:00:00

  • Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion.

    abstract:BACKGROUND AND AIMS:Crohn's disease (CD) ileal lesions are colonised by pathogenic adherent-invasive Escherichia coli (AIEC) producing outer membrane vesicles (OMVs) that contribute to the bacterial invasion process. In addition, increased expression of endoplasmic reticulum (ER)-localised stress response proteins, due...


    pub_type: 杂志文章


    authors: Rolhion N,Barnich N,Bringer MA,Glasser AL,Ranc J,Hébuterne X,Hofman P,Darfeuille-Michaud A

    更新日期:2010-10-01 00:00:00

  • Treatment of 'cimetidine-resistant' chronic duodenal ulcers with ranitidine or cimetidine: a randomised multicentre study.

    abstract::Forty patients with endoscopically proven persistent duodenal ulcer who had been treated for six weeks with cimetidine (1 g/day) were randomly allocated to receive a further six weeks' treatment with cimetidine (1 g/day) or ranitidine (300 mg/day). Ulcers healed in 12 of 19 patients given cimetidine (63%) and in 13 of...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Quatrini M,Basilisco G,Bianchi PA

    更新日期:1984-10-01 00:00:00

  • Phenotype and function of HBV-specific T cells is determined by the targeted epitope in addition to the stage of infection.

    abstract:OBJECTIVE:Chronic HBV infection affects more than 250 million people worldwide and remains a global healthcare problem in part because we lack curative treatment. Sustained viral control requires HBV-specific T cells, but these become functionally impaired in chronic infection. Clinical evidence indicates that function...


    pub_type: 杂志文章


    authors: Hoogeveen RC,Robidoux MP,Schwarz T,Heydmann L,Cheney JA,Kvistad D,Aneja J,Melgaço JG,Fernandes CA,Chung RT,Boonstra A,Kim AY,Baumert TF,Timm J,Lewis-Ximenez LL,Tonnerre P,Lauer GM

    更新日期:2019-05-01 00:00:00

  • Does treatment of Helicobacter pylori with antibiotics alone heal duodenal ulcer? A randomised double blind placebo controlled study.

    abstract:BACKGROUND:Treatment of Helicobacter pylori infection prevents duodenal ulcer relapse. It has not been established if treatment of the infection heals duodenal ulcer. AIM:To test the hypothesis that treatment of the infection was associated with healing of duodenal ulcer. METHODS:A randomised, double blind placebo co...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Lam SK,Ching CK,Lai KC,Wong BC,Lai CL,Chan CK,Ong L

    更新日期:1997-07-01 00:00:00

  • Treatment of patients with dual hepatitis C and B by peginterferon α and ribavirin reduced risk of hepatocellular carcinoma and mortality.

    abstract:OBJECTIVE:Whether peginterferon α and ribavirin combination therapy reduces risk of hepatocellular carcinoma (HCC) or improves survival in patients dual-infected with hepatitis C virus (HCV) and hepatitis B virus (HBV) is unknown. Since it is ethically impossible to conduct a randomised trial to learn the long-term eff...


    pub_type: 杂志文章


    authors: Liu CJ,Chu YT,Shau WY,Kuo RN,Chen PJ,Lai MS

    更新日期:2014-03-01 00:00:00

  • Molecular testing for antibiotic resistance in Helicobacter pylori.

    abstract::An estimated 7.5 million individuals in England and Wales are actively infected with Helicobacter pylori and hence knowledge of local resistance rates is of growing importance. Also, information on strain resistance following treatment failure is crucial in selecting an appropriate regimen as the development of bacter...


    pub_type: 杂志文章,评审


    authors: Owen RJ

    更新日期:2002-03-01 00:00:00

  • Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome.

    abstract:OBJECTIVE:The complex genetic aetiology underlying irritable bowel syndrome (IBS) needs to be assessed in large-scale genetic studies. Two independent IBS cohorts were genotyped to assess whether genetic variability in immune, neuronal and barrier integrity genes is associated with IBS. DESIGN:384 single nucleotide po...


    pub_type: 杂志文章


    authors: Wouters MM,Lambrechts D,Knapp M,Cleynen I,Whorwell P,Agréus L,Dlugosz A,Schmidt PT,Halfvarson J,Simrén M,Ohlsson B,Karling P,Van Wanrooy S,Mondelaers S,Vermeire S,Lindberg G,Spiller R,Dukes G,D'Amato M,Boeckxstaens

    更新日期:2014-07-01 00:00:00

  • Long-term follow-up of patients on home parenteral nutrition in Europe: implications for intestinal transplantation.

    abstract:BACKGROUND:The indications for intestinal transplantation (ITx) are still debated. Knowing survival rates and causes of death on home parenteral nutrition (HPN) will improve decisions. METHODS:A prospective 5-year study compared 389 non-candidates (no indication, no contraindication) and 156 candidates (indication, no...


    pub_type: 杂志文章,多中心研究


    authors: Pironi L,Joly F,Forbes A,Colomb V,Lyszkowska M,Baxter J,Gabe S,Hébuterne X,Gambarara M,Gottrand F,Cuerda C,Thul P,Messing B,Goulet O,Staun M,Van Gossum A,Home Artificial Nutrition & Chronic Intestinal Failure Working Grou

    更新日期:2011-01-01 00:00:00

  • Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats.

    abstract:BACKGROUND AND AIM:Hepatic stellate cells (HSCs) are key participants in liver fibrosis development. 1,25(OH)(2)D(3), the active form of vitamin D, has antiproliferative properties and antifibrotic potential, as well as a role in extracellular matrix and matrix metalloproteinase (MMP) regulation in renal and lung fibro...


    pub_type: 杂志文章


    authors: Abramovitch S,Dahan-Bachar L,Sharvit E,Weisman Y,Ben Tov A,Brazowski E,Reif S

    更新日期:2011-12-01 00:00:00

  • Zollinger-Ellison syndrome type 1: clinical and pathological correlations in a case.

    abstract::Some patients with the Zollinger-Ellison syndrome appear to have hypergastrinaemia and hyperplasia of the antral G cells but no tumour. This subgroup has been classified as Zollinger-Ellison syndrome type 1. We have treated such a patient by vagotomy and antrectomy, the fasting plasma gastrin and acid secretion subseq...


    pub_type: 杂志文章


    authors: Cowley DJ,Dymock IW,Boyes BE,Wilson RY,Stagg BH,Lewin MR,Polak JM,Pearse AG

    更新日期:1973-01-01 00:00:00

  • Substantial and sustained improvement of serrated polyp detection after a simple educational intervention: results from a prospective controlled trial.

    abstract:OBJECTIVE:Serrated polyps (SPs) are an important cause of postcolonoscopy colorectal cancers (PCCRCs), which is likely the result of suboptimal SP detection during colonoscopy. We assessed the long-term effect of a simple educational intervention focusing on optimising SP detection. DESIGN:An educational intervention,...


    pub_type: 杂志文章


    authors: Bleijenberg AGC,van Leerdam ME,Bargeman M,Koornstra JJ,van Herwaarden YJ,Spaander MC,Sanduleanu S,Bastiaansen BAJ,Schoon EJ,van Lelyveld N,Dekker E,IJspeert JEG

    更新日期:2020-12-01 00:00:00

  • Ulcerative colitis--a disease characterised by the abnormal colonic epithelial cell?

    abstract::The leakiness of the cell membranes of colonic epithelial cells isolated by the collagenase/Dispase technique from normal or diseased colons was assessed in a 4 h 51Cr release assay. Cells from normal, adenoma bearing or cancer bearing colons showed 51Cr release of 8% or less in almost all of 46 cell populations teste...


    pub_type: 杂志文章


    authors: Gibson PR,van de Pol E,Barratt PJ,Doe WF

    更新日期:1988-04-01 00:00:00

  • Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α.

    abstract:OBJECTIVE:Cryptogenic multifocal ulcerating stenosing enteritis (CMUSE) is an extremely rare, but devastating, disease of unknown aetiology. We investigated the genetic basis of this autosomal recessive condition in a pair of affected siblings who have 40-year histories of catastrophic gastrointestinal and extraintesti...


    pub_type: 杂志文章


    authors: Brooke MA,Longhurst HJ,Plagnol V,Kirkby NS,Mitchell JA,Rüschendorf F,Warner TD,Kelsell DP,MacDonald TT

    更新日期:2014-01-01 00:00:00

  • Anti-inflammatory role of sympathetic nerves in chronic intestinal inflammation.

    abstract:BACKGROUND:Substance P (SP) is a pro-inflammatory neuropeptide in colitis, whereas sympathetic neurotransmitters are anti-inflammatory at high concentrations. AIM AND METHODS:In all layers of the colon, nerve fibre densities of SP(+) and sympathetic nerve fibres were investigated (22 Crohn's disease, six diverticuliti...


    pub_type: 杂志文章


    authors: Straub RH,Grum F,Strauch U,Capellino S,Bataille F,Bleich A,Falk W,Schölmerich J,Obermeier F

    更新日期:2008-07-01 00:00:00

  • In vivo assessment of granulocyte migration to diseased bowel in Crohn's disease.

    abstract::It has been suggested, on the basis of impaired granulocyte migration to skin windows, that there is a fundamental granulocyte defect in Crohn's disease. In vitro tests of granulocyte function have, however, failed to confirm this. We have studied granulocyte migration to inflamed bowel in Crohn's disease using a new ...


    pub_type: 杂志文章


    authors: Saverymuttu SH,Peters AM,Lavender JP,Chadwick VS,Hodgson HJ

    更新日期:1985-04-01 00:00:00

  • Glutathione peroxidase 7 has potential tumour suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma.

    abstract:OBJECTIVE:To investigate the potential tumour suppressor functions of glutathione peroxidase 7 (GPX7) and examine the interplay between epigenetic and genetic events in regulating its expression in oesophageal adenocarcinomas (OAC). DESIGN:In vitro and in vivo cell models were developed to investigate the biological a...


    pub_type: 杂志文章


    authors: Peng D,Hu T,Soutto M,Belkhiri A,Zaika A,El-Rifai W

    更新日期:2014-04-01 00:00:00

  • GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.

    abstract:BACKGROUND AND AIMS:The role of GATA factors in cancer has gained increasing attention recently, but the function of GATA6 in pancreatic ductal adenocarcinoma (PDAC) is controversial. GATA6 is amplified in a subset of tumours and was proposed to be oncogenic, but high GATA6 levels are found in well-differentiated tumou...


    pub_type: 杂志文章


    authors: Martinelli P,Carrillo-de Santa Pau E,Cox T,Sainz B Jr,Dusetti N,Greenhalf W,Rinaldi L,Costello E,Ghaneh P,Malats N,Büchler M,Pajic M,Biankin AV,Iovanna J,Neoptolemos J,Real FX

    更新日期:2017-09-01 00:00:00

  • Nodular regenerative hyperplasia mimicking cirrhosis of the liver.

    abstract::Nodular regenerative hyperplasia of the liver usually presents with signs of portal hypertension with little evidence of obvious liver disease. We report a 47 year old man who presented with clinical signs of decompensated cirrhosis, recurrent encephalopathy, and tense ascites but at liver transplant was found to have...


    pub_type: 杂志文章


    authors: McDonald JA,Painter DM,Gallagher ND,McCaughan GW

    更新日期:1990-06-01 00:00:00

  • Nippostrongylus brasiliensis infection in the rat: effect of iron and protein deficiency on the anthelmintic efficacy of mebendazole, pyrantel, piperazine, and levamisole.

    abstract::The benzimidazole anthelmintics mebendazole and fenbendazole have been shown to be much less effective against Nippostrongylus brasiliensis infections in the rat on a combined iron and protein deficient diet. In the present experiments it was shown that the anthelmintic efficacy of mebendazole was significantly impair...


    pub_type: 杂志文章


    authors: Duncombe VM,Bolin TD,Davis AE,Fagan MR,Kelly JD

    更新日期:1979-04-01 00:00:00

  • Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles.

    abstract:BACKGROUND:The normal intestinal microflora plays an important role in host metabolism and provides a natural defence mechanism against invading pathogens. Although the microbiota in adults has been extensively studied, little is known of the changes that occur in the microflora with aging. These may have important con...


    pub_type: 杂志文章


    authors: Hopkins MJ,Sharp R,Macfarlane GT

    更新日期:2001-02-01 00:00:00

  • International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis.

    abstract:OBJECTIVE:In this consensus statement, an international panel of experts deliver their opinions on key questions regarding the contribution of the human microbiome to carcinogenesis. DESIGN:International experts in oncology and/or microbiome research were approached by personal communication to form a panel. A structu...


    pub_type: 共识发展会议,杂志文章


    authors: Scott AJ,Alexander JL,Merrifield CA,Cunningham D,Jobin C,Brown R,Alverdy J,O'Keefe SJ,Gaskins HR,Teare J,Yu J,Hughes DJ,Verstraelen H,Burton J,O'Toole PW,Rosenberg DW,Marchesi JR,Kinross JM

    更新日期:2019-09-01 00:00:00

  • An assessment of the value of serum cholinesterase as a liver function test and in the diagnosis of jaundice.

    abstract::This report assesses the value of cholinesterase (ChE) activity as an indicator of liver function and analyses its usefulness in the diagnosis of jaundice. A rapid method of determination has been used, and alterations in ChE activity in conditions other than liver disease have been studied to permit a fuller and more...


    pub_type: 杂志文章


    authors: BURNETT W

    更新日期:1960-12-01 00:00:00

  • Is sclerosant injection mandatory after an epinephrine injection for arrest of peptic ulcer haemorrhage? A prospective, randomised, comparative study.

    abstract::A prospective, randomised, comparative study was performed to assess the need for a pure alcohol injection after an epinephrine injection in the arrest of active peptic ulcer bleeding. Sixty four patients with active ulcer bleeding were enrolled in the study. The two groups (epinephrine and epinephrine plus pure alcoh...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Lin HJ,Perng CL,Lee SD

    更新日期:1993-09-01 00:00:00

  • Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin release.

    abstract::Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin secretion were studied by using the isolated perfused rat stomach. [Asu1,7]-eel calcitonin (10(-9)--10(-7)M) caused a simultaneous dose-dependent increase of gastric somatostatin release and decrease of gastrin secretion, with a significant correla...


    pub_type: 杂志文章


    authors: Chiba T,Taminato T,Kadowaki S,Goto Y,Mori K,Seino Y,Abe H,Chihara K,Matsukura S,Fujita T,Kondo T

    更新日期:1980-02-01 00:00:00

  • Effect of Helicobacter pylori eradication on the treatment of gastro-oesophageal reflux disease.

    abstract::The important issue of whether Heliobacter pylori eradication leads to increased reflux has been the subject of many apparently contradictory publications, but when we asked two leading authorities to give us their views, there turned out to be considerable consensus, as you can read below. ...


    pub_type: 杂志文章


    authors: Richter JE

    更新日期:2004-02-01 00:00:00

  • Jaundice due to carbimazole.

    abstract::On three occasions, a 63 year old housewife with hyperthyroidism developed a reaction which included fever, pruritus, malaise, and, on one occasion, jaundice one to 17 days after taking carbimazole. Challenge with carbimazole was followed within 12 hours by abdominal pain, pruritus, and increased serum transaminase le...


    pub_type: 杂志文章


    authors: Lunzer M,Huang SN,Ginsburg J,Ahmed M,Sherlock S

    更新日期:1975-11-01 00:00:00

  • Gastrin studies in gastric ulcer.

    abstract::Basal serum gastrin in 40 patients with benign gastric ulcer was 103 +/- 10.7 pg/ml, a level significantly higher than corresponding estimations in normal subjects and patients with duodenal ulcer. Following stimulation by a protein meal, a mean rise of 124 pg/ml was achieved at 75 minutes and prior atropinization ind...


    pub_type: 杂志文章


    authors: Korman MG,Soveny C,Hansky J

    更新日期:1972-03-01 00:00:00

  • Portal and systemic haemodynamic action of N-acetylcysteine in patients with stable cirrhosis.

    abstract::The effects of intravenous N-acetylcysteine on hepatic and systemic haemodynamics were investigated in 11 patients with stable cirrhosis (eight alcohol; two primary biliary cirrhosis; one cryptogenic). N-acetylcysteine administration had no effect on the mean heart rate or mean arterial blood pressure despite a signif...


    pub_type: 杂志文章


    authors: Jones AL,Bangash IH,Bouchier IA,Hayes PC

    更新日期:1994-09-01 00:00:00

  • Malignant histiocytosis of the intestine: the early histological lesion.

    abstract::A histological study of peroral jejunal biopsies and resection specimens from patients with malignant histiocytosis of the intestine (MHI) has revealed characteristic lesions consisting of intramucosal histiocytic aggregations which invade surface and crypt epithelium. These lesions are found in 'uninvolved' jejunal m...


    pub_type: 杂志文章


    authors: Isaacson P

    更新日期:1980-05-01 00:00:00