Gastro-oesophageal reflux disease and Helicobacter pylori: an intricate relation.

abstract：BACKGROUND:The incidence figures for ulcerative colitis (UC) and Crohn's disease (CD) have been difficult to interpret, and geographical variations may be due to differences in classification criteria and study design. Few studies have based the incidence on prospective systematic follow up to confirm the initial diagn...

journal_title：Gut

authors： Moum B,Ekbom A,Vatn MH,Aadland E,Sauar J,Lygren I,Schulz T,Stray N,Fausa O

更新日期：1997-03-01 00:00:00

abstract：:Vagal and spinal afferents represent the information superhighways that convey sensory information from the gut to the central nervous system. These afferents are sensitive to both mechanical and chemical stimuli. Vagal afferents terminate in the muscle layers and in the mucosa. Muscle afferents are activated at physi...

journal_title：Gut

authors： Grundy D

更新日期：2004-03-01 00:00:00

abstract：:The extent to which defects in protein synthesis occurred in an experimental indomethacin induced rat model of nonsteroidal enteropathy has been examined. Male rats (nine) were fed indomethacin (8 mg/kg/day) for three days mixed with a powdered form of chow. The control group of rats (nine) were fed the same diet for ...

journal_title：Gut

authors： Banerjee AK,Marway JS,Preedy VR,Peters TJ

更新日期：1992-02-01 00:00:00

abstract：:The influence of carbenoxolone on the synthesis of glycoproteins in the surface mucous cells and the production of new cells in the rat gastric mucosa was studied by means of a vascular perfusion system. The rate of incorporation of tritiated galactose, glucosamine, serine, and sulphate in surface mucous cells, studie...

journal_title：Gut

authors： van Huis GA,Kramer MF

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Extrahepatic manifestations of HCV are responsible for morbidity and mortality in many chronically infected patients. New, interferon-free antiviral treatment regimens, which present the opportunity to treat all HCV-infected patients, call for a better understanding of the benefits of treating non-c...

journal_title：Gut

authors： Cacoub P,Desbois AC,Comarmond C,Saadoun D

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To clarify the prognostic role of tumour protein 53 (TP53) mutations in patients with oesophageal adenocarcinoma (OAC) as there is a need for biomarkers that assist in guiding management for patients with OAC. DESIGN:A systematic review was conducted using MEDLINE, Embase, PubMed and Current Contents Connect...

journal_title：Gut

authors： Fisher OM,Lord SJ,Falkenback D,Clemons NJ,Eslick GD,Lord RV

更新日期：2017-03-01 00:00:00

abstract：:Three-day faecal collections were obtained from 87 patients with a variety of gastroenterological diagnoses and 12 control subjects while consuming normal diets. Faecal weight, total fatty acids, and the proportion of hydroxystearic (OHSA) acid were measured. All patients had some easily detectable hydroxystearic acid...

journal_title：Gut

authors： Wiggins HS,Pearson JR,Walker JG,Russell RI,Kellock TD

更新日期：1974-08-01 00:00:00

abstract：BACKGROUND/AIM:To examine the risks for hepatocellular carcinoma (HCC) with respect to hepatitis B virus (HBV) genotypes, specific viral mutations (MT), serum HBV DNA levels, and cirrhosis. METHODS:HBV genotypes, 1653/1753/core promoter (CP)/precore MT and HBV DNA levels were determined in 248 HBV patients with HCC an...

journal_title：Gut

authors： Yuen MF,Tanaka Y,Shinkai N,Poon RT,But DY,Fong DY,Fung J,Wong DK,Yuen JC,Mizokami M,Lai CL

更新日期：2008-01-01 00:00:00

abstract：:Carriers of beta amino acids and imino acids in the small intestine of rabbits and guinea pigs are chloride dependent, and a cotransport of chloride, sodium, and 2-methyl-aminoisobutyric acid has been shown. This study examines the chloride dependence of amino acid transport in the human small intestine. The steady st...

journal_title：Gut

authors： Munck LK

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:In human acute pancreatitis two different types of secretory phospholipase A2 (PLA2) have been found. AIM:To analyse the specific pattern of distribution of these PLA2 activities and their pathophysiological role in experimental acute pancreatitis. SUBJECTS AND METHODS:Catalytic activities of secretory typ...

journal_title：Gut

authors： Uhl W,Schrag HJ,Schmitter N,Nevalainen TJ,Aufenanger J,Wheatley AM,Büchler MW

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Endoscopic surveillance for Barrett's oesophagus (BO) is under discussion given the overall low incidence of neoplastic progression and lack of evidence that it prevents advanced oesophageal adenocarcinoma (OAC). The aim of this study was to evaluate the impact of endoscopic BO surveillance on tumour stage an...

journal_title：Gut

authors： Kastelein F,van Olphen SH,Steyerberg EW,Spaander MC,Bruno MJ,ProBar-Study Group.

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Oligodeoxynucleotides (ODNs) containing unmethylated cytosine-guanosine (CpG) sequence motifs constitute the immunostimulatory components of bacterial DNA which potently activate innate immunity. Administration of CpG-ODNs before the onset of experimental colitis prevents intestinal inflammation by induction...

journal_title：Gut

authors： Hofmann C,Dunger N,Grunwald N,Hämmerling GJ,Hoffmann P,Schölmerich J,Falk W,Obermeier F

更新日期：2010-10-01 00:00:00

abstract：:We previously noted a region of amino acid sequence homology between A-gliadin, a major alpha-gliadin component known to activate coeliac disease, and the early region E1b protein of human adenovirus serotype 12 (Ad12), an adenovirus isolated from the human intestinal tract. In the present study sera from coeliac dise...

journal_title：Gut

authors： Kagnoff MF,Paterson YJ,Kumar PJ,Kasarda DD,Carbone FR,Unsworth DJ,Austin RK

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:TFF1 is a 6.5 kDa secreted protein that is expressed predominantly in normal gastric mucosa. It is coexpressed with mucins and it can form dimers via a free carboxy terminal cysteine residue. AIMS:To investigate the molecular forms of TFF1 that are present in normal human stomach and the association of the ...

journal_title：Gut

authors： Newton JL,Allen A,Westley BR,May FE

更新日期：2000-03-01 00:00:00

abstract：:The use of tripotassium dicitrato bismuthate (TDB) has been suggested recently for cimetidine resistant duodenal ulcers. This study compares the efficacy of TDB with two different cimetidine dosages in the treatment of duodenal ulcer patients who failed to respond to an eight week therapy with H2-blockers. Fifty two p...

journal_title：Gut

authors： Bianchi Porro G,Parente F,Lazzaroni M

更新日期：1987-07-01 00:00:00

abstract：:Jejunal biopsies from 15 Greenlandic and three Danish patients with adult type hypolactasia and nine Greenlandic and 15 Danish patients with normal lactase activity were analysed quantitatively for lactase protein by crossed immunoelectrophoresis. A constant correlation between the amount of lactase activity and immun...

journal_title：Gut

authors： Skovbjerg H,Gudmand-Høyer E,Fenger HJ

更新日期：1980-05-01 00:00:00

abstract：OBJECTIVE:Persistent colonisation by Helicobacter pylori, and especially by cagA-positive strains, has been related to several health outcomes with effects in opposite directions. Thus, it is important to evaluate its influence on total and category-specific mortality. DESIGN:We conducted prospective cohort analyses i...

journal_title：Gut

authors： Chen Y,Segers S,Blaser MJ

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:In association with innate and adaptive immunity, the microbiota controls the colonisation resistance against intestinal pathogens. Caspase recruitment domain 9 (CARD9), a key innate immunity gene, is required to shape a normal gut microbiota. Card9-/- mice are more susceptible to the enteric mouse pathogen C...

journal_title：Gut

authors： Lamas B,Michel ML,Waldschmitt N,Pham HP,Zacharioudaki V,Dupraz L,Delacre M,Natividad JM,Costa GD,Planchais J,Sovran B,Bridonneau C,Six A,Langella P,Richard ML,Chamaillard M,Sokol H

更新日期：2018-10-01 00:00:00

abstract：:Acute fulminant pancreatitis is associated with significant morbidity and mortality. To examine the outcome of conservative and surgical treatment of this disorder, 36 patients who survived an initial episode were restudied after a mean of six years. Fifty three per cent had developed diabetes mellitus, half of whom r...

journal_title：Gut

authors： Eriksson J,Doepel M,Widén E,Halme L,Ekstrand A,Groop L,Höckerstedt K

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:To present comparative data about the performance of colorectal cancer (CRC) screening programmes in the European Union Member States (EU MSs). DESIGN:Cross-sectional study. We analysed key performance indicators-participation rate, positivity rate (PR), detection rate (DR) and positive predictive value for ...

journal_title：Gut

authors： Senore C,Basu P,Anttila A,Ponti A,Tomatis M,Vale DB,Ronco G,Soerjomataram I,Primic-Žakelj M,Riggi E,Dillner J,Elfström MK,Lönnberg S,Sankaranarayanan R,Segnan N

更新日期：2019-07-01 00:00:00

abstract：:The biomechanical properties of the oesophageal wall were investigated in a rabbit model using a four electrode impedance technique. A specially designed probe with the electrodes inside a low pressure expandable insulating latex balloon was introduced in the oesophagus. Stepwise inflation and deflation was done for a...

journal_title：Gut

authors： Gregersen H,Jensen LS,Djurhuus JC

更新日期：1988-12-01 00:00:00

abstract：:The actions of hydrochloric acid, natural PGE1, PGE2 and a synthetic commercial PGE1 preparation, Enisoprost (Searle) on pepsinogen synthesis and secretion were studied in canine chief cell monolayer cultures. Hydrochloric acid, applied directly to the apical surface of chief cells using culture plate inserts (Millipo...

journal_title：Gut

authors： Defize J,Hunt RH

更新日期：1989-06-01 00:00:00

abstract：:The mucosal potential difference in the body of the stomach was measured in 18 patients with gastric ulcers, five with gastritis, and three with pernicious anaemia. The results were compared with those of 12 normal volunteers. Significantly lower than normal levels were found in the groups of patients with gastric ulc...

journal_title：Gut

authors： Hossenbocus A,Fitzpatrick P,Colin-Jones DG

更新日期：1976-12-01 00:00:00

abstract：:Completeness of vagotomy has been assessed by use of the electrical stimulation test and the insulin test in 50 patients suffering from chronic duodenal ulceration. A positive result from either was taken as evidence of incomplete vagotomy. The electrical stimulation test provided such evidence more often than the ins...

journal_title：Gut

authors： Hollanders D

更新日期：1971-08-01 00:00:00

abstract：AIMS:To study fracture rates and risk factors for fractures in patients with Crohn's disease and ulcerative colitis. METHODS:998 self administered questionnaires were issued to members of the Danish Colitis/Crohn Association, and 1000 questionnaires were issued to randomly selected control subjects. 845 patients (84.5...

journal_title：Gut

authors： Vestergaard P,Krogh K,Rejnmark L,Laurberg S,Mosekilde L

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:Hippo signalling is a recently identified major oncosuppressive pathway that plays critical roles in inhibiting hepatocyte proliferation, survival and hepatocellular carcinoma (HCC) formation. Hippo kinase (Mst1 and Mst2) inhibits HCC proliferation by suppressing Yap/Taz transcription activities. As human HCC...

journal_title：Gut

authors： Kim W,Khan SK,Liu Y,Xu R,Park O,He Y,Cha B,Gao B,Yang Y

更新日期：2018-09-01 00:00:00

abstract：:Gastric mucosal blood flow in the rat was determined by the indicator fractionation technique of Sapirstein using Rb86Cl. Antral and corpus flow rates were determined in response to increasing doses of pentagastrin and histamine and the effect of vagotomy was determined. With progressive stimulation the antral:corpus ...

journal_title：Gut

authors： Taylor TV,Pullan BR,Goddard J,Torrance B

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:In the revised Atlanta classification of acute pancreatitis, the term necrotising pancreatitis also refers to patients with only extrapancreatic fat necrosis without pancreatic parenchymal necrosis (EXPN), as determined on contrast-enhanced CT (CECT). Patients with EXPN are thought to have a better clinical o...

journal_title：Gut

authors： Bakker OJ,van Santvoort H,Besselink MG,Boermeester MA,van Eijck C,Dejong K,van Goor H,Hofker S,Ahmed Ali U,Gooszen HG,Bollen TL,Dutch Pancreatitis Study Group.

更新日期：2013-10-01 00:00:00

abstract：:The incidence of small intestinal colonization in unoperated duodenal ulcer patients was low and similar to that in the normal population. The majority of patients seven to 10 days following truncal vagotomy and drainage were colonized whereas none of a control group of patients following simple closure of a perforate...

journal_title：Gut

authors： Browning GG,Buchan KA,Mackay C

更新日期：1974-02-01 00:00:00

abstract：:The mechanism by which intragastric balloons induce weight loss is not known, although they may act simply by reducing the amount of food needed to induce satiety. The knowledge that a balloon is present may influence the patients' eating patterns and reduce caloric intake and weight. In order to test whether the ball...

journal_title：Gut

authors： Ramhamadany EM,Fowler J,Baird IM

更新日期：1989-08-01 00:00:00