Laboratory diagnosis of gastrointestinal bleeding.

abstract：:Gastric acid secretion, pepsin secretion, and fasting serum gastrin levels were measured in 23 patients with duodenal ulcer disease, divided into three groups which received either cimetidine 800 mg daily, cimetidine 1600 mg daily, or ranitidine hydrochloride 300 mg daily for eight weeks. Pentagastrin tests were carri...

journal_title：Gut

authors： Mohammed R,Holden RJ,Hearns JB,McKibben BM,Buchanan KD,Crean GP

更新日期：1983-01-01 00:00:00

abstract：:In a prospective survey positive antimitochondrial antibodies have been detected in 69/4200 (1.64%) of all sera submitted to a routine immunology laboratory. Of the 69, only nine patients had uniquivocal primary biliary cirrhosis, six others had chronic active hepatitis, 10 had abnormal liver function tests without ev...

journal_title：Gut

authors： Triger DR,Charlton CA,Ward AM

更新日期：1982-10-01 00:00:00

abstract：:Colorectal cancer is the fourth commonest form of cancer in men with 678 000 estimated new cases per year worldwide, representing 8.9% of all new cancers. The disease is most frequent in Occidental countries and particularly so in North America, Australia, New Zealand, and parts of Europe. Prospects for colorectal can...

journal_title：Gut

authors： Langman M,Boyle P

更新日期：1998-10-01 00:00:00

abstract：:To determine the optimum dose of ispaghula husk in patients with irritable bowel syndrome (IBS) and to assess the correlation, if any between the relief in patients' symptoms and the whole gut transit time, and the increase in stool weight, a two part study was carried out. In part 1, 14 male patients were given ispag...

journal_title：Gut

authors： Kumar A,Kumar N,Vij JC,Sarin SK,Anand BS

更新日期：1987-02-01 00:00:00

abstract：:It has been proposed that anti-inflammatory actions of corticosteroids rely on promotion of a natural peptide phospholipase A2 inhibitor, lipocortin, but in vivo effects on arachidonic acid metabolism have not been shown. Equilibrium dialysis of the rectum in patients with ulcerative colitis was used to determine whet...

journal_title：Gut

authors： Lauritsen K,Laursen LS,Bukhave K,Rask-Madsen J

更新日期：1987-09-01 00:00:00

abstract：:Results from a recent, new assay suggest that omeprazole, a potent inhibitor of gastric acid secretion, is genotoxic. The principle of this assay is that the non-proliferating zone of surface gastric epithelial cells can be selectively removed by controlled digestion so that any incorporation of tritiated thymidine in...

journal_title：Gut

authors： Goodlad RA,Lee CY,Alison MR,Sarraf CE,Ghatei MA,Bloom SR,Wright NA

更新日期：1993-02-01 00:00:00

abstract：:CLINICAL PRESENTATION: A 51-year-old man, who had no previous disease, underwent a screening oesophagogastroduodenoscopy, which revealed multiple yellowish lesions in the middle thoracic oesophagus. All lesions were ≤3 mm in size and slightly elevated. Each lesion showed one or two white protrusions on the surface (fi...

journal_title：Gut

authors： Hamada K,Yamasaki Y,Kubota JI,Okada H

更新日期：2019-01-01 00:00:00

abstract：:An improved technique for the detection of alpha-gliadin sensitised mononuclear cells in the peripheral blood of untreated coeliac patients is described. This method is a modification of the direct LMIF assay, and involves exposure of lymphocytes to alpha-gliadin and the assay of the resultant lymphokine produced usin...

journal_title：Gut

authors： O'Farrelly C,Feighery C,Greally JF,Weir DG

更新日期：1982-01-01 00:00:00

abstract：:Gastroparesis is defined by the presence of delayed gastric emptying (GE) in the absence of mechanical obstruction. Symptoms that have been attributed to gastroparesis include postprandial fullness, early satiation nausea and vomiting. Gastroprokinetic drugs are the preferred treatment option. A number of problems wit...

journal_title：Gut

authors： Stanghellini V,Tack J

更新日期：2014-12-01 00:00:00

abstract：:Ultrastructural examination of biopsies showing Helicobacter pylori associated chronic gastritis reveals close attachment between gastric surface epithelial cells and the organism. The finding of 'adhesion pedestals', which represents a cellular response to the presence of the organism, is analogous to the response of...

journal_title：Gut

authors： Hessey SJ,Spencer J,Wyatt JI,Sobala G,Rathbone BJ,Axon AT,Dixon MF

更新日期：1990-02-01 00:00:00

abstract：:The role of Helicobacter pylori infection in the pathogenesis of functional dyspepsia is debated. It is known that a substantial fraction of dyspeptic patients manifest a low discomfort threshold to gastric distension. This study investigated the symptomatic pattern in 27 H pylori positive and 23 H pylori negative pat...

journal_title：Gut

authors： Mearin F,de Ribot X,Balboa A,Salas A,Varas MJ,Cucala M,Bartolomé R,Armengol JR,Malagelada JR

更新日期：1995-07-01 00:00:00

abstract：:The endothelins are a group of three related peptides with two receptor subtypes, ET(A) and ET(B). Following the discovery of endothelin 1 as a potent vasoconstrictor, there has been intense interest in the role of endothelin on vascular function in liver disease. Speculation on the role of endothelin in the pathogene...

journal_title：Gut

authors： Moore K

更新日期：2004-02-01 00:00:00

abstract：:We determined the ionic composition of faecal fluid from 13 patients with Crohn's disease limited to the colon, 10 with diffuse ulcerative colitis, and eight with ulcerative proctitis. The Crohn's and colitis groups had similar proportions of colon surface involved radiographically and similar 24 hour faecal weights. ...

journal_title：Gut

authors： Schilli R,Breuer RI,Klein F,Dunn K,Gnaedinger A,Bernstein J,Paige M,Kaufman M

更新日期：1982-04-01 00:00:00

abstract：:The major end products of fermentation, short chain fatty acids (acetate, propionate, butyrate) were measured in portal and peripheral venous blood after the caecal instillation of lactulose at surgery in patients undergoing elective cholecystectomy. Blood samples for short chain fatty acid measurement were taken befo...

journal_title：Gut

authors： Peters SG,Pomare EW,Fisher CA

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:Osteoporosis and fractures are frequently encountered in patients with Crohn's disease. In order to prevent fractures, treatment with bone protecting drugs appears warranted early in the course of bone disease when bone loss is not yet prominent. We therefore aimed to demonstrate a beneficial effect on bone d...

journal_title：Gut

authors： van Bodegraven AA,Bravenboer N,Witte BI,Dijkstra G,van der Woude CJ,Stokkers PC,Russel MG,Oldenburg B,Pierik M,Roos JC,van Hogezand RA,Dik VK,Oostlander AE,Netelenbos JC,van de Langerijt L,Hommes DW,Lips P,Dutch Initiat

更新日期：2014-09-01 00:00:00

abstract：:Studies have been made of mucus glycoprotein biosynthesis in different regions of the lower gastrointestinal tract in normal patients and those with ulcerative colitis (UC), active or inactive, by means of 3H-glucosamine (3H-GlcNH2)--35S-sulphate double labelling of epithelial biopsy specimens under culture conditions...

journal_title：Gut

authors： Morita H,Kettlewell MG,Jewell DP,Kent PW

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVES:To determine the therapeutic equivalence and safety of once daily (OD) versus three times daily (TID) dosing of a total daily dose of 3 g Salofalk (mesalazine) granules in patients with active ulcerative colitis. DESIGN:A randomised, double-blind, double-dummy, parallel group, multicentre, international, ph...

journal_title：Gut

authors： Kruis W,Kiudelis G,Rácz I,Gorelov IA,Pokrotnieks J,Horynski M,Batovsky M,Kykal J,Boehm S,Greinwald R,Mueller R,International Salofalk OD Study Group.

更新日期：2009-02-01 00:00:00

abstract：:Thirty two patients with active Crohn's disease were included in a controlled randomised trial to determine the efficacy and safety of polymeric enteral nutrition compared with steroids, to achieve and maintain clinical remission. The polymeric diet was administered through a fine bore nasogastric tube by continuous, ...

journal_title：Gut

authors： González-Huix F,de León R,Fernández-Bañares F,Esteve M,Cabré E,Acero D,Abad-Lacruz A,Figa M,Guilera M,Planas R

更新日期：1993-06-01 00:00:00

abstract：:The investigation and treatment of 131 patients with 'obscure' gastrointestinal bleeding has been reviewed. One hundred and six patients were assessed electively for recurrent haemorrhage, 25 presented as emergencies. The major presenting feature was melaena (55 patients), anaemia (35), rectal bleeding (34), haemateme...

journal_title：Gut

authors： Thompson JN,Salem RR,Hemingway AP,Rees HC,Hodgson HJ,Wood CB,Allison DJ,Spencer J

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Polyamines are essential for cell growth. Dietary and probably gut bacterial derived polyamines contribute significantly to the polyamine body pool. AIMS:To evaluate the influence of dietary, luminal polyamines on growth and development of different gastrointestinal organs in normally growing rats. METHODS...

journal_title：Gut

authors： Löser C,Eisel A,Harms D,Fölsch UR

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIMS:In 1998 the PPP2R1B gene encoding the A subunit of the serine/threonine protein phosphatase was identified as a putative tumour suppressor gene in lung and colon cancer in the chromosome region 11q22-24. The aim of the present study was to determine the type of alterations in primary rectal cancers as w...

journal_title：Gut

authors： Takagi Y,Futamura M,Yamaguchi K,Aoki S,Takahashi T,Saji S

更新日期：2000-08-01 00:00:00

abstract：:Serumfolate folate levels and the bacteriology of the small intestine were studied in 13 patients with jejunal diverticulosis, 29 patients with partial gastrectomy, and five patients with ileal disease. The mean serum folate level in the patients with partial gastrectomy (7.2 mmug/ml) was similar to that of control su...

journal_title：Gut

authors： Hoffbrand AV,Tabaqchali S,Booth CC,Mollin DL

更新日期：1971-01-01 00:00:00

abstract：:Macrophage major histocompatibility complex (MHC) class II antigen expression is associated with defective antigen presentation to T lymphocytes in animals and is predictive of patient outcome after major trauma or sepsis. In this study, class II antigen (HLA-DR and DQ) expression on peripheral blood monocytes was inv...

journal_title：Gut

authors： Gardiner KR,Crockard AD,Halliday MI,Rowlands BJ

更新日期：1994-04-01 00:00:00

abstract：:The increase in activities of hepatic thymidylate synthetase (EC 2.1.1.45) and thymidine kinase (EC 2.7.1.21), which catalyse the formation of thymidylate through the de novo and salvage pathways, respectively, were significantly suppressed during liver regeneration in rats which were given glucocorticoids (hydrocorti...

journal_title：Gut

authors： Tsukamoto I,Kojo S

更新日期：1989-03-01 00:00:00

abstract：:Quantitative and qualitative disturbances in faecal flora suggest a role for enteric bacteria and their products in the pathogenesis of inflammatory bowel disease (IBD). This study investigated the hypothesis that systemically circulating endotoxins are of pathogenic significance in IBD by measuring antibody, cytokine...

journal_title：Gut

authors： Gardiner KR,Halliday MI,Barclay GR,Milne L,Brown D,Stephens S,Maxwell RJ,Rowlands BJ

更新日期：1995-06-01 00:00:00

abstract：:A technique for obtaining needle aspiration cytology specimens from upper gastrointestinal lesions at endoscopy is described. The validity of the technique was initially confirmed by applying it to resected gastric carcinomas. Thirty seven endoscopically visualised lesions were then sampled by forceps biopsy, brush an...

journal_title：Gut

authors： Ingoldby CJ,Mason MK,Hall RI

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Micrometastases within bone marrow have been shown to indicate a poor prognosis in patients with epithelial tumours. However, the degree to which micrometastases represent true residual disease or cell shedding and metastatic potential, is unclear. AIM:To explore whether micrometastases represent residual d...

journal_title：Gut

authors： O'Sullivan GC,Collins JK,Kelly J,Morgan J,Madden M,Shanahan F

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Standard triple therapies are the most used treatment in clinical practice. However, a critical fall in the H pylori eradication rate following these therapies has been observed in the last few years. The sequential regimen is a novel, promising therapeutic approach. OBJECTIVES:To evaluate the available dat...

journal_title：Gut

authors： Zullo A,De Francesco V,Hassan C,Morini S,Vaira D

更新日期：2007-10-01 00:00:00

abstract：:The faecal blood loss of six alcoholic subjects with normal gastric mucosa, six with superficial gastritis, and six with atrophic gastritis was studied before and during ingestion of 40% v/v ethanol using (51)Cr-tagged red blood cells. No significant change in faecal blood loss was observed in the normal mucosa and su...

journal_title：Gut

authors： Dinoso VP Jr,Meshkinpour H,Lorber SH

更新日期：1973-04-01 00:00:00

abstract：BACKGROUND:Because hepatic cirrhosis is a major risk factor for hepatocellular carcinoma, recent guidelines by the European Association for the Study of the Liver (EASL) on clinical management of hepatocellular carcinoma recommend periodic ultrasound surveillance of cirrhotic patients with immediate workup for nodules ...

journal_title：Gut

authors： Caturelli E,Solmi L,Anti M,Fusilli S,Roselli P,Andriulli A,Fornari F,Del Vecchio Blanco C,de Sio I

更新日期：2004-09-01 00:00:00