Significance of systemic endotoxaemia in inflammatory bowel disease.

abstract：:An estimated 7.5 million individuals in England and Wales are actively infected with Helicobacter pylori and hence knowledge of local resistance rates is of growing importance. Also, information on strain resistance following treatment failure is crucial in selecting an appropriate regimen as the development of bacter...

journal_title：Gut

authors： Owen RJ

更新日期：2002-03-01 00:00:00

abstract：:Gastric acid secretion, pepsin secretion, and fasting serum gastrin levels were measured in 23 patients with duodenal ulcer disease, divided into three groups which received either cimetidine 800 mg daily, cimetidine 1600 mg daily, or ranitidine hydrochloride 300 mg daily for eight weeks. Pentagastrin tests were carri...

journal_title：Gut

authors： Mohammed R,Holden RJ,Hearns JB,McKibben BM,Buchanan KD,Crean GP

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of GATA factors in cancer has gained increasing attention recently, but the function of GATA6 in pancreatic ductal adenocarcinoma (PDAC) is controversial. GATA6 is amplified in a subset of tumours and was proposed to be oncogenic, but high GATA6 levels are found in well-differentiated tumou...

journal_title：Gut

authors： Martinelli P,Carrillo-de Santa Pau E,Cox T,Sainz B Jr,Dusetti N,Greenhalf W,Rinaldi L,Costello E,Ghaneh P,Malats N,Büchler M,Pajic M,Biankin AV,Iovanna J,Neoptolemos J,Real FX

更新日期：2017-09-01 00:00:00

abstract：:Histochemical enzymatic studies were performed on 30 freshly resected large bowel carcinomas, 30 samples of normal colonic epithelium, and six samples of the histologically normal epithelium (so-called transitional epithelium) immediately adjacent to a carcinoma. Five enzymes were studied: nicotine adenine dinucleotid...

journal_title：Gut

authors： Marsden JR,Dawson IM

更新日期：1974-10-01 00:00:00

abstract：:Eighteen patients with achalasia of the cardia diagnosed by radiography, endoscopy, and manometry were subjected to forced pneumatic dilatation under fluoroscopic control. The procedure was uneventful in all but one patient who developed a pneumomediastinum which resolved on conservative management. A satisfactory res...

journal_title：Gut

authors： Lishman AH,Dellipiani AW

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Familial adenomatous polyposis (FAP) is a clinically well defined hereditary disease caused by germline mutations within the adenomatous polyposis coli (APC) gene. Although several techniques are applied in the mutation analysis of FAP kindreds about 20-50% of cases remain unclear, with no APC mutation ident...

journal_title：Gut

authors： Heinimann K,Müllhaupt B,Weber W,Attenhofer M,Scott RJ,Fried M,Martinoli S,Müller H,Dobbie Z

更新日期：1998-11-01 00:00:00

abstract：:Patients with primary biliary cirrhosis have a defect in the receptor mediated clearance of complement coated erythrocytes by fixed macrophages of the reticuloendothelial system. To investigate the probable mechanism of this defect peripheral blood monocytes were isolated from nine patients with primary biliary cirrho...

journal_title：Gut

authors： Minuk GY,Vergalla J,Hanson RG,Hoofnagle JH,Frank MM,Jones EA

更新日期：1986-03-01 00:00:00

abstract：:The possibility that the mode of action of sulphasalazine and its active metabolite 5-amino-salicylic acid (5ASA) involves modification of toxic oxygen metabolite production by neutrophils has been investigated by measuring the effect of these drugs on luminol-dependent chemiluminescence, superoxide release and oxygen...

journal_title：Gut

authors： Williams JG,Hallett MB

更新日期：1989-11-01 00:00:00

abstract：AIM:To compare acceptability and diagnostic accuracy of a recently available faecal immunochemical test (FIT) system (HM-JACKarc) with the FIT routinely used in an established screening programme (OC-Sensor). DESIGN:Randomised controlled trial (ISRCTN20086618) within a population-based colorectal cancer (CRC) screenin...

journal_title：Gut

authors： Passamonti B,Malaspina M,Fraser CG,Tintori B,Carlani A,D'Angelo V,Galeazzi P,Di Dato E,Mariotti L,Bulletti S,D'Amico MR,Gustinucci D,Martinelli N,Spita N,Cesarini E,Rubeca T,Giaimo M,Segnan N,Senore C

更新日期：2018-03-01 00:00:00

abstract：:Computed tomography detected the presence of dilated ducts in 15 of 18 cases with extrahepatic obstructive jaundice and demonstrated the obstructing lesion in 18 out of 25. The cause of the obstruction was detected in the absence of duct dilatation, and calculi which were radiolucent on conventional radiographs were d...

journal_title：Gut

authors： Morris A,Fawcitt RA,Wood R,Forbes WS,Isherwood I,Marsh MN

更新日期：1978-08-01 00:00:00

abstract：OBJECTIVE:Non-coeliac gluten sensitivity (NCGS) is characterised by intestinal and extraintestinal symptoms related to the ingestion of gluten-containing foods, in the absence of coeliac disease (CD) and wheat allergy. No biomarkers are available to diagnose NCGS and the gold standard double-blind placebo-controlled gl...

journal_title：Gut

authors： Barbaro MR,Cremon C,Morselli-Labate AM,Di Sabatino A,Giuffrida P,Corazza GR,Di Stefano M,Caio G,Latella G,Ciacci C,Fuschi D,Mastroroberto M,Bellacosa L,Stanghellini V,Volta U,Barbara G

更新日期：2020-11-01 00:00:00

abstract：:Paracetamol poisoning is the most common cause of fulminant liver failure in the United Kingdom. An accurate assessment of prognosis at the time of referral will allow the appropriate application of liver transplantation in this setting. The outcome of 92 patients consecutively admitted to a specialist liver unit with...

journal_title：Gut

authors： Mutimer DJ,Ayres RC,Neuberger JM,Davies MH,Holguin J,Buckels JA,Mayer AD,McMaster P,Elias E

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:The incidence figures for ulcerative colitis (UC) and Crohn's disease (CD) have been difficult to interpret, and geographical variations may be due to differences in classification criteria and study design. Few studies have based the incidence on prospective systematic follow up to confirm the initial diagn...

journal_title：Gut

authors： Moum B,Ekbom A,Vatn MH,Aadland E,Sauar J,Lygren I,Schulz T,Stray N,Fausa O

更新日期：1997-03-01 00:00:00

abstract：:The benzimidazole anthelmintics mebendazole and fenbendazole have been shown to be much less effective against Nippostrongylus brasiliensis infections in the rat on a combined iron and protein deficient diet. In the present experiments it was shown that the anthelmintic efficacy of mebendazole was significantly impair...

journal_title：Gut

authors： Duncombe VM,Bolin TD,Davis AE,Fagan MR,Kelly JD

更新日期：1979-04-01 00:00:00

abstract：:Salivary amylase output in man increases after injection of synthetic human calcitonin. This effect is dose dependent. ...

journal_title：Gut

authors： Drack GT,Koelz HR,Blum AL

更新日期：1976-08-01 00:00:00

abstract：:Patients with the Peutz-Jeghers syndrome carry a slight, though definite, increased risk of gastrointestinal carcinoma. The malignant potentiality of Peutz-Jeghers hamartomatous polyps, generally considered benign, is supported by this report. Two cases of metastasising gastrointestinal carcinoma associated with the P...

journal_title：Gut

authors： Cochet B,Carrel J,Desbaillets L,Widgren S

更新日期：1979-02-01 00:00:00

abstract：:Bacterial contamination of gastrointestinal fibre-endoscopes is a potential source of clinically significant infection. Aqueous 2% alkaline glutaraldehyde adequately disinfects fibre-endoscopes but may cause serious sensitivity reactions among endoscopy staff. A new 'closed-system' disinfecting apparatus is described ...

journal_title：Gut

authors： O'Connor HJ,Rothwell J,Maxwell S,Lincoln C,Axon AT

更新日期：1982-08-01 00:00:00

abstract：:The value of four tests to detect occult alimentary blood loss has been compared in normal subjects, in patients with and without alimentary disease, and in patients with congestive heart failure, and the sensitivities of these tests have been compared using suspensions of blood alone and blood in faeces. The Occultes...

journal_title：Gut

authors： Steingold L,Roberts AA

更新日期：1961-03-01 00:00:00

abstract：OBJECTIVE:Metabolic syndrome (MetS) arises from complex interactions between host genetic and environmental factors. Although it is now widely accepted that the gut microbiota plays a crucial role in host metabolism, current knowledge on the effect of host genetics on specific gut microbes related to MetS status remain...

journal_title：Gut

authors： Lim MY,You HJ,Yoon HS,Kwon B,Lee JY,Lee S,Song YM,Lee K,Sung J,Ko G

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:To develop an affordable and robust pipeline for selection of patient-specific somatic structural variants (SSVs) being informative about radicality of the primary resection, response to adjuvant therapy, incipient recurrence and response to treatment performed in relation to diagnosis of recurrence. DESIGN:...

journal_title：Gut

authors： Reinert T,Schøler LV,Thomsen R,Tobiasen H,Vang S,Nordentoft I,Lamy P,Kannerup AS,Mortensen FV,Stribolt K,Hamilton-Dutoit S,Nielsen HJ,Laurberg S,Pallisgaard N,Pedersen JS,Ørntoft TF,Andersen CL

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND AIM:There are few data on the course of Helicobacter pylori infection in asymptomatic subjects. The aim of this study was to assess the effect of eradication therapy on the development of dyspeptic and gastro-oesophageal reflux disease in a cohort of asymptomatic individuals observed over a prolonged per...

journal_title：Gut

authors： Vaira D,Vakil N,Rugge M,Gatta L,Ricci C,Menegatti M,Leandro G,Holton J,Russo VM,Miglioli M

更新日期：2003-11-01 00:00:00

abstract：:The frequency of gastric Crohn's disease has been considered low. This study was undertaken to determine the prevalence of chronic gastritis and Helicobacter pylori infection in patients with Crohn's disease. Oesophagogastroduodenoscopy was performed on 62 consecutive patients suffering from ileocolonic Crohn's diseas...

journal_title：Gut

authors： Halme L,Kärkkäinen P,Rautelin H,Kosunen TU,Sipponen P

更新日期：1996-03-01 00:00:00

abstract：:Forty two white patients of British or Irish descent with coeliac disease and 28 with dermatitis herpetiformis were typed for class I HLA-A, B, and C, and class II DR and DQ antigens. In coeliac disease there was a significant increase in the frequencies of A1, B8, DR3, DR7, and DQw2 compared with controls but no incr...

journal_title：Gut

authors： Sachs JA,Awad J,McCloskey D,Navarrete C,Festenstein H,Elliot E,Walker-Smith JA,Griffiths CE,Leonard JN,Fry L

更新日期：1986-05-01 00:00:00

abstract：:This paper describes the construction and use of "radio pills" which transmit changes in intraluminar pressure. ...

journal_title：Gut

authors： CONNELL AM,ROWLANDS EN

更新日期：1960-09-01 00:00:00

abstract：OBJECTIVE:Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive type of GI tumour, and it possesses deregulated cellular energetics. Although recent advances in PDAC biology have led to the discovery of recurrent genetic mutations in Kras, TP53 and SMAD4, which are related to this disease, clinical application...

journal_title：Gut

authors： Liang C,Shi S,Qin Y,Meng Q,Hua J,Hu Q,Ji S,Zhang B,Xu J,Yu XJ

更新日期：2020-05-01 00:00:00

abstract：:THE SMOOTH MUSCLE SPHINCTERIC ACTIVITY OF THE ANUS IN CATS IS BASED ON TWO DISTINCT MECHANISMS: a typical anal component, characterized by anal slow pressure waves not related to spike potentials in the internal anal sphincter, and an intestinal-like pressure component related to spiking activity in the internal sphin...

journal_title：Gut

authors： Kerremans R,Penninckx F

更新日期：1970-08-01 00:00:00

abstract：:Water and electrolyte balance has been studied in 39 patients with a permanent ileostomy, who had had a proctocolectomy for ulcerative colitis. The findings have been compared with those in 39 healthy subjects who were matched for age and sex. The ileostomists were found to lose excessive quantities of water and sodiu...

journal_title：Gut

authors： Kennedy HJ,Al-Dujaili EA,Edwards CR,Truelove SC

更新日期：1983-08-01 00:00:00

abstract：:In dogs with either vagally innervated or denervated pouches, the acid responses to a standard meal, a meal which bypassed the greater part of the small bowel, and a meal introduced directly into the small intestine were measured before and after exclusion of 75% of the small bowel.After intestinal exclusion an increa...

journal_title：Gut

authors： Buxton B,Wasunna AE,Saunders J,Gillespie IE

更新日期：1972-07-01 00:00:00

abstract：:Eight patients with diffuse plasma cell infiltration of the small bowel who had the clinical features of immunoproliferative small intestinal disease (IPSID), but whose serum was negative for free alpha-heavy chains, were investigated for evidence of a non-secretory form of alpha-chain disease (alpha-CD). Molecular si...

journal_title：Gut

authors： Gilinsky NH,Mee AS,Beatty DW,Novis BH,Young G,Price S,Purves LR,Marks IN

更新日期：1985-09-01 00:00:00

abstract：:The role of lamina propria cells in regulating human colonic ion transport was investigated in vitro. Normal human colonic mucosae were mounted in Ussing chambers, and short circuit current changes (delta SCC) were monitored in response to immune cell activation. Anti-human immunoglobulin E (anti-IgE) and formyl-Methi...

journal_title：Gut

authors： Stack WA,Keely SJ,O'Donoghue DP,Baird AW

更新日期：1995-03-01 00:00:00