Micrometastases: marker of metastatic potential or evidence of residual disease?

abstract：:A manometric method was developed to study the motor activity in the unprepared human colon, and the results in eight healthy subjects were compared with those obtained in the same subjects after bowel cleansing with a non-absorbable solution containing polyethylene glycol 4000 (PEG). A tube assembly (4.5 m long, 12 l...

journal_title：Gut

authors： Lémann M,Flourié B,Picon L,Coffin B,Jian R,Rambaud JC

更新日期：1995-11-01 00:00:00

abstract：:Continued bleeding or early rebleeding is associated with a poor prognosis in patients with variceal haemorrhage. It is not clear why bleeding stops in some patients and continues or restarts in others. It is suggested that secondary haemodynamic changes in the splanchnic circulation after a bleed may contribute to th...

journal_title：Gut

authors： McCormick PA,Jenkins SA,McIntyre N,Burroughs AK

更新日期：1995-01-01 00:00:00

abstract：:The value of four tests to detect occult alimentary blood loss has been compared in normal subjects, in patients with and without alimentary disease, and in patients with congestive heart failure, and the sensitivities of these tests have been compared using suspensions of blood alone and blood in faeces. The Occultes...

journal_title：Gut

authors： Steingold L,Roberts AA

更新日期：1961-03-01 00:00:00

abstract：:Prostaglandins (PGs) are synthesised by gastric mucosa, and have been shown to inhibit gastric acid secretion and ulcer formation in man and experimental animals. Recently exogenous PGs, mainly of the E group, have been used for the treatment of peptic ulcer disease. We therefore searched for a drug that would stimula...

journal_title：Gut

authors： Ligumsky M,Rachmilewitz D,Zor U

更新日期：1979-10-01 00:00:00

abstract：:A method not needing fluoroscopic control for positioning a manometric probe in the gastroduodenal tract is described. It is based on hydrostatic pressure variations occurring at each recording port of a multichannel perfused probe after changes in patient's position. The data are fed into a computer and the schematic...

journal_title：Gut

authors： Bortolotti M,Bersani G

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:To investigate the success rate of cold snare polypectomy (CSP) for complete resection of 4-9 mm colorectal adenomatous polyps compared with that of hot snare polypectomy (HSP). DESIGN:A prospective, multicentre, randomised controlled, parallel, non-inferiority trial conducted in 12 Japanese endoscopy units....

journal_title：Gut

authors： Kawamura T,Takeuchi Y,Asai S,Yokota I,Akamine E,Kato M,Akamatsu T,Tada K,Komeda Y,Iwatate M,Kawakami K,Nishikawa M,Watanabe D,Yamauchi A,Fukata N,Shimatani M,Ooi M,Fujita K,Sano Y,Kashida H,Hirose S,Iwagami H,

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND/AIMS:In 1998 the PPP2R1B gene encoding the A subunit of the serine/threonine protein phosphatase was identified as a putative tumour suppressor gene in lung and colon cancer in the chromosome region 11q22-24. The aim of the present study was to determine the type of alterations in primary rectal cancers as w...

journal_title：Gut

authors： Takagi Y,Futamura M,Yamaguchi K,Aoki S,Takahashi T,Saji S

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Postpolypectomy surveillance guidelines for colorectal cancer introduced the concept of 'risk stratification'; however, few studies have been conducted for validation of its usefulness. The aim of this study was to assess the 5-year incidence of advanced neoplasia recurrence based on the risk stratification s...

journal_title：Gut

authors： Chung SJ,Kim YS,Yang SY,Song JH,Kim D,Park MJ,Kim SG,Song IS,Kim JS

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Inflammatory bowel disease (IBD) is initiated and perpetuated by a dysregulated immune response to unknown environmental antigens such as luminal bacteria in genetically susceptible hosts. SR-PSOX/CXCL16, a scavenger receptor that binds phosphatidylserine and oxidised lipoprotein, has both phagocyti...

journal_title：Gut

authors： Uza N,Nakase H,Yamamoto S,Yoshino T,Takeda Y,Ueno S,Inoue S,Mikami S,Matsuura M,Shimaoka T,Kume N,Minami M,Yonehara S,Ikeuchi H,Chiba T

更新日期：2011-11-01 00:00:00

abstract：:Peptide histidine isoleucine, a 27 amino acid peptide with close amino acid sequence homology to vasoactive intestinal peptide and secretin, is distributed throughout the mammalian intestinal tract, where it has been localised to intramural neurones. An intestinal perfusion technique has been used to study the effect ...

journal_title：Gut

authors： Moriarty KJ,Hegarty JE,Tatemoto K,Mutt V,Christofides ND,Bloom SR,Wood JR

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Coeliac disease (CD) is triggered by an abnormal reaction to gluten. Peptides resulting from partially digested gluten of wheat, barley or rye cause inflammation of the small intestinal mucosa. Previous contradictory studies suggest that oats may trigger the abnormal immunological response in patien...

journal_title：Gut

authors： Comino I,Real A,de Lorenzo L,Cornell H,López-Casado MÁ,Barro F,Lorite P,Torres MI,Cebolla A,Sousa C

更新日期：2011-07-01 00:00:00

abstract：:In normal subjects the length of the functional anal sphincter has been compared with the extent of sensation to light touch in the anal canal. At rest, the sphincteric zone was the longer. On distension of the rectum, a decrease in pressure in the anal canal so shortened the functional sphincter that intrarectal pres...

journal_title：Gut

authors： Duthie HL,Bennett RC

更新日期：1963-06-01 00:00:00

abstract：:The cognitive model of depression assigns a central role to negatively biased information processing in the pathogenesis of the emotional disorder. The relationship between depression and irritable bowel syndrome (IBS) was explored from a cognitive perspective. A word recognition memory task was constructed: subjects ...

journal_title：Gut

authors： Gomborone JE,Dewsnap PA,Libby GW,Farthing MJ

更新日期：1993-09-01 00:00:00

abstract：:Earlier studies have reported that faecal pH is more alkaline in patients with colonic cancer, indicating a reduction in colonic carbohydrate fermentation to organic acids. The pH of faeces from 11 pre and 14 postoperative, selected colonic cancer patients without intestinal obstruction, major loss of appetite or weig...

journal_title：Gut

authors： Hove H,Rye Clausen M,Brøbech Mortensen P

更新日期：1993-05-01 00:00:00

abstract：:Oral disodium cromoglycate (200 mg qds) has been tested in 26 patients with ulcerative colitis that was resistant to medical treatment. In a double-blind crossover trial disodium cromoglycate and placebo were added to conventional treatment in random order, each for four weeks. There was no significant difference in t...

journal_title：Gut

authors： Buckell NA,Gould SR,Day DW,Lennard-Jones JE,Edwards AM

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Teduglutide, a GLP-2 analogue, may restore intestinal structural and functional integrity by promoting repair and growth of the mucosa and reducing gastric emptying and secretion, thereby increasing fluid and nutrient absorption in patients with short bowel syndrome (SBS). This 24-week placebo-contr...

journal_title：Gut

authors： Jeppesen PB,Gilroy R,Pertkiewicz M,Allard JP,Messing B,O'Keefe SJ

更新日期：2011-07-01 00:00:00

abstract：:The use of tripotassium dicitrato bismuthate (TDB) has been suggested recently for cimetidine resistant duodenal ulcers. This study compares the efficacy of TDB with two different cimetidine dosages in the treatment of duodenal ulcer patients who failed to respond to an eight week therapy with H2-blockers. Fifty two p...

journal_title：Gut

authors： Bianchi Porro G,Parente F,Lazzaroni M

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Patients with long-standing UC have an increased risk for the development of colonic neoplastic lesions. Chromoendoscopy (CE) has been proven to enhance neoplasia detection while the role of virtual chromoendoscopy (VC) is still to be defined. OBJECTIVE:To compare the performance of CE to VC for the detecti...

journal_title：Gut

authors： Bisschops R,Bessissow T,Joseph JA,Baert F,Ferrante M,Ballet V,Willekens H,Demedts I,Geboes K,De Hertogh G,Vermeire S,Rutgeerts P,Van Assche G

更新日期：2018-06-01 00:00:00

abstract：:Forty two white patients of British or Irish descent with coeliac disease and 28 with dermatitis herpetiformis were typed for class I HLA-A, B, and C, and class II DR and DQ antigens. In coeliac disease there was a significant increase in the frequencies of A1, B8, DR3, DR7, and DQw2 compared with controls but no incr...

journal_title：Gut

authors： Sachs JA,Awad J,McCloskey D,Navarrete C,Festenstein H,Elliot E,Walker-Smith JA,Griffiths CE,Leonard JN,Fry L

更新日期：1986-05-01 00:00:00

abstract：:Calcium palmitate occurred in 20% of the gallstones studied in this laboratory by x-ray diffraction and was the most important crystalline constituent after the different forms of cholesterol and calcium carbonate. Only one calculus contained alpha-palmitic acid. The gallstones came from America, England, Australia, S...

journal_title：Gut

authors： Sutor DJ

更新日期：1970-07-01 00:00:00

abstract：:There has been a vast increase in GI literature focused on the use of machine learning in endoscopy. The relative novelty of this field poses a challenge for reviewers and readers of GI journals. To appreciate scientific quality and novelty of machine learning studies, understanding of the technical basis and commonly...

journal_title：Gut

authors： van der Sommen F,de Groof J,Struyvenberg M,van der Putten J,Boers T,Fockens K,Schoon EJ,Curvers W,de With P,Mori Y,Byrne M,Bergman JJGHM

更新日期：2020-11-01 00:00:00

abstract：:Hydrogen breath tests are widely used to explore the pathophysiology of functional gastrointestinal disorders. Small intestinal bacterial overgrowth and carbohydrate malabsorption are disorders detected by these tests that have been proposed to be of great importance for symptoms in, for instance, irritable bowel synd...

journal_title：Gut

authors： Simrén M,Stotzer PO

更新日期：2006-03-01 00:00:00

abstract：:We determined the ionic composition of faecal fluid from 13 patients with Crohn's disease limited to the colon, 10 with diffuse ulcerative colitis, and eight with ulcerative proctitis. The Crohn's and colitis groups had similar proportions of colon surface involved radiographically and similar 24 hour faecal weights. ...

journal_title：Gut

authors： Schilli R,Breuer RI,Klein F,Dunn K,Gnaedinger A,Bernstein J,Paige M,Kaufman M

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The incidence of oesophageal adenocarcinoma (OAC) has been increasing rapidly with a dismal survival rate of less than 20%. Understanding the genomic aberrations and biology of this cancer may enhance disease interventions. This study aimed to use genome-wide genomic and expression data to enhance t...

journal_title：Gut

authors： Goh XY,Rees JR,Paterson AL,Chin SF,Marioni JC,Save V,O'Donovan M,Eijk PP,Alderson D,Ylstra B,Caldas C,Fitzgerald RC

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Adaptive immune resistance mediated by the cytokine interferon gamma (IFNG) still constitutes a major problem in cancer immunotherapy. We develop strategies for overcoming IFNG-mediated adaptive immune resistance in pancreatic ductal adenocarcinoma cancer (PDAC). DESIGN:We screened 429 kinase inhibitors for ...

journal_title：Gut

authors： Huang J,Chen P,Liu K,Liu J,Zhou B,Wu R,Peng Q,Liu ZX,Li C,Kroemer G,Lotze M,Zeh H,Kang R,Tang D

更新日期：2020-08-14 00:00:00

abstract：OBJECTIVE:Early detection and early treatment are of vital importance to the successful treatment of various cancers. The development of a novel screening method that is as economical and non-invasive as the faecal occult blood test (FOBT) for early detection of colorectal cancer (CRC) is needed. A study was undertaken...

journal_title：Gut

authors： Sonoda H,Kohnoe S,Yamazato T,Satoh Y,Morizono G,Shikata K,Morita M,Watanabe A,Morita M,Kakeji Y,Inoue F,Maehara Y

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The role of the recently discovered GB virus C (GBV-C)/hepatitis G virus in fulminant hepatic failure (FHF) has been debated. Although GBV-C RNA has been detected in many cases of FHF, recent data suggest that the relation between GBV-C and FHF may be accidental. AIMS:To retrospectively investigate the poss...

journal_title：Gut

authors： Halasz R,Barkholt L,Lara C,Hultgren C,Ando Y,Broomé U,Fischler B,Nemeth A,Ericzon BG,Sönnerborg A,Sällberg M

更新日期：1999-02-01 00:00:00

abstract：:The effects of low power (1-2 Watts), long exposure (30-400 seconds), interstitial Nd YAG laser therapy on dimethylhydrazine induced rat colonic neoplasms and normal rat colon have been studied. After a single exposure with appropriate laser parameters, dimethylhydrazine induced rat colonic neoplasms underwent coagula...

journal_title：Gut

authors： Matthewson K,Barton T,Lewin MR,O'Sullivan JP,Northfield TC,Bown SG

更新日期：1988-01-01 00:00:00

abstract：:Partial gastrectomy and intestinal resection significantly impaired glucose tolerance (p < 0.05) and significantly decreased the release of insulin by intravenous glucose (p < 0.05) or a meal of minced beef (p < 0.01). There was a significantly greater release of insulin one hour after oral glucose in the gastrectomy ...

journal_title：Gut

authors： Wapnick S,Jones JJ

更新日期：1972-11-01 00:00:00

abstract：OBJECTIVE:Recent evidence suggesting an important role of gut-derived inflammation in brain disorders has opened up new directions to explore the possible role of the gut-brain axis in neurodegenerative diseases. Given the prominence of dysbiosis and colonic dysfunction in patients with Parkinson's disease (PD), we pro...

journal_title：Gut

authors： Perez-Pardo P,Dodiya HB,Engen PA,Forsyth CB,Huschens AM,Shaikh M,Voigt RM,Naqib A,Green SJ,Kordower JH,Shannon KM,Garssen J,Kraneveld AD,Keshavarzian A

更新日期：2019-05-01 00:00:00