Effect of Helicobacter pylori eradication on the treatment of gastro-oesophageal reflux disease.

abstract：BACKGROUND:Gastric mucosal surface hydrophobicity (GMSH) is an essential component of the mucosal defence system that is decreased by Helicobacter pylori and non-steroidal anti-inflammatory drugs (NSAIDs). Gastric ulcers occur predominantly in elderly subjects, and may thus reflect diminished mucosal resistance. AIMS:...

journal_title：Gut

authors： Hackelsberger A,Platzer U,Nilius M,Schultze V,Günther T,Dominguez-Muñoz JE,Malfertheiner P

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The diagnostic yield of capsule endoscopy (CE) compared with magnetic resonance imaging (MRI) in small bowel Crohn's disease is not well established. We prospectively investigated CE, MRI, and double contrast fluoroscopy in patients with suspected small bowel Crohn's disease. METHODS:Fifty two cons...

journal_title：Gut

authors： Albert JG,Martiny F,Krummenerl A,Stock K,Lesske J,Göbel CM,Lotterer E,Nietsch HH,Behrmann C,Fleig WE

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Fresh fruit and vegetables exert multiple biological effects on the gastrointestinal mucosa. AIM:To assess whether apple extracts counteract oxidative or indomethacin induced damage to gastric epithelial cells in vitro and to rat gastric mucosa in vivo. METHODS:Apple extracts were obtained from freeze drie...

journal_title：Gut

authors： Graziani G,D'Argenio G,Tuccillo C,Loguercio C,Ritieni A,Morisco F,Del Vecchio Blanco C,Fogliano V,Romano M

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Dietary folate is believed to protect against colorectal cancer (CRC). However, few studies have addressed the role of circulating levels of folate. The aim of this study was to relate prediagnostic plasma folate and homocysteine concentrations and the methylenetetrahydrofolate reductase (MTHFR) 677...

journal_title：Gut

authors： Van Guelpen B,Hultdin J,Johansson I,Hallmans G,Stenling R,Riboli E,Winkvist A,Palmqvist R

更新日期：2006-10-01 00:00:00

abstract：:Serumfolate folate levels and the bacteriology of the small intestine were studied in 13 patients with jejunal diverticulosis, 29 patients with partial gastrectomy, and five patients with ileal disease. The mean serum folate level in the patients with partial gastrectomy (7.2 mmug/ml) was similar to that of control su...

journal_title：Gut

authors： Hoffbrand AV,Tabaqchali S,Booth CC,Mollin DL

更新日期：1971-01-01 00:00:00

abstract：BACKGROUND:We previously described hepatitis reactivation in two carriers of the hepatitis C virus (HCV) genotype 2c. AIM:To assess the relationship between HCV genotypes and risk of hepatitis reactivation, we studied the course of aminotransferases in patients infected with the two relevant genotypes in Italy. PATIE...

journal_title：Gut

authors： Rumi MG,De Filippi F,La Vecchia C,Donato MF,Gallus S,Del Ninno E,Colombo M

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The detection of hepatocellular cancers (HCC) is a major role of preoperative imaging in patients with end stage liver disease being considered for orthotopic liver transplantation (OLT). AIMS:To assess the sensitivity of iodised oil computed tomography (IOCT). PATIENTS AND METHODS:A prospective evaluation...

journal_title：Gut

authors： Saada J,Bhattacharya S,Dhillon AP,Dick R,Burroughs AK,Rolles K,Davidson BR

更新日期：1997-09-01 00:00:00

abstract：:The activity of an interferon induced enzyme, (2',5') oligo adenylate synthetase, was determined in peripheral blood mononuclear cells and granulocytes of patients with inflammatory bowel disease and compared with its activity in cells isolated from normal subjects. In spite of the fact that circulating interferon is ...

journal_title：Gut

authors： Stalnikowicz R,Goder K,Karmeli F,Fiocchi C,Rachmilewitz D

更新日期：1985-06-01 00:00:00

abstract：:Little is known about chronic constipation in infants, toddlers, and preschool children and longterm outcome after treatment. The symptoms of 174 children < or = 4 years of age, who were evaluated for chronic constipation, are reported in this study together with the long-term outcome in 90 of them. Initial symptoms w...

journal_title：Gut

authors： Loening-Baucke V

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Glucagon-like peptide 2 (GLP-2) may improve intestinal absorption in short bowel syndrome (SBS) patients with an end jejunostomy. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant GLP-2 analogue, prolongs the intestinotrophic properties of GLP-2 in animal models. The safety and effect of t...

journal_title：Gut

authors： Jeppesen PB,Sanguinetti EL,Buchman A,Howard L,Scolapio JS,Ziegler TR,Gregory J,Tappenden KA,Holst J,Mortensen PB

更新日期：2005-09-01 00:00:00

abstract：:The cholesteryl-14C-octanoate breath test was used to monitor the intraluminal enzymatic activity of pancreatin preparations in six patients with severe pancreatic insufficiency. Conventional enzyme replacement, with cimetidine as an adjunct, was compared to supplementation with enteric coated microspheres. In healthy...

journal_title：Gut

authors： Mundlos S,Kühnelt P,Adler G

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND AIM:The lymphatic network plays a major role in maintaining tissue fluid homoeostasis. Therefore several pathological conditions associated with oedema formation result in deficient lymphatic function. However, the role of the lymphatic system in the pathogenesis of ascites and oedema formation in cirrho...

journal_title：Gut

authors： Ribera J,Pauta M,Melgar-Lesmes P,Tugues S,Fernández-Varo G,Held KF,Soria G,Tudela R,Planas AM,Fernández-Hernando C,Arroyo V,Jiménez W,Morales-Ruiz M

更新日期：2013-01-01 00:00:00

abstract：:Fasting insulin, lipids and lipoproteins were measured in 22 middle aged female non-insulin dependent diabetics with gall stone disease (cases) and in 22 non-insulin dependent diabetics without gall stone disease (controls). The groups were matched for sex, age, obesity, and fasting glucose concentrations. No differen...

journal_title：Gut

authors： Laakso M,Suhonen M,Julkunen R,Pyörälä K

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Mouse models of colitis and cancer are indispensable for our understanding of the pathogenesis of these diseases. In the past, mice had to be sacrificed in order to analyse colitis activity and tumour development. We have developed a safe method for high resolution endoscopic monitoring of living mice. METH...

journal_title：Gut

authors： Becker C,Fantini MC,Wirtz S,Nikolaev A,Kiesslich R,Lehr HA,Galle PR,Neurath MF

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Whole body catabolism as the result of intrahepatic metabolic derangement is common in liver transplant candidates. However, individual nutritional assessment parameters lack sensitivity and specificity in determining energy status of these patients. Recently, serum hepatocyte growth factor (HGF) has been sh...

journal_title：Gut

authors： Miki C,Mayer AD,Buckels JA,Iriyama K,Suzuki H,McMaster P

更新日期：1999-06-01 00:00:00

abstract：:Coeliac disease is triggered by ingestion of wheat gliadin and is probably immune mediated. There is evidence by light microscopy that expression of class II major histocompatibility complex (MHC) molecules is increased in the small intestinal epithelium of patients with untreated coeliac disease and that gliadin can ...

journal_title：Gut

authors： Zimmer KP,Poremba C,Weber P,Ciclitira PJ,Harms E

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Most colon cancers start with dysregulated Wnt/β-catenin signalling and remain a major therapeutic challenge. Examining whether HAMLET (human α-lactalbumin made lethal to tumour cells) may be used for colon cancer treatment is logical, based on the properties of the complex and its biological context. OBJEC...

journal_title：Gut

authors： Puthia M,Storm P,Nadeem A,Hsiung S,Svanborg C

更新日期：2014-01-01 00:00:00

abstract：:Carbenoxolone (Biogastrone, Berk) has been shown to reduce the peptic activity and total acidity of gastric juice obtained from anaesthetized pylorus-ligated rats without affecting significantly the volume of gastric juice secreted or the K(+) concentration. Glycyrrhetinic acid was less potent in reducing peptic activ...

journal_title：Gut

authors： Henman FD

更新日期：1970-04-01 00:00:00

abstract：:The effects on gastric emptying of a solid meal of the specific 5-HT3-receptor antagonist ICS 205-930, 10 mg and 20 mg intravenously were assessed with a scintigraphic technique in 12 normals. The 50% emptying time was less, the lag phase was shorter and the post lag emptying rate was faster after 20 mg ICS 205-930 (p...

journal_title：Gut

authors： Akkermans LM,Vos A,Hoekstra A,Roelofs JM,Horowitz M

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVE:Gastric carcinoma development is triggered by Helicobacter pylori. Chronic H. pylori infection leads to reduced acid secretion, which may allow the growth of a different gastric bacterial community. This change in the microbiome may increase aggression to the gastric mucosa and contribute to malignancy. Our a...

journal_title：Gut

authors： Ferreira RM,Pereira-Marques J,Pinto-Ribeiro I,Costa JL,Carneiro F,Machado JC,Figueiredo C

更新日期：2018-02-01 00:00:00

abstract：:Previous studies have shown that ileal infusion of partially digested triglyceride inhibits jejunal motility. The partial digest used in those studies contained a mixture of glycerol, free fatty acid, mono-, di-, and triglycerides. In Part I of the present study we have separately infused emulsions containing either g...

journal_title：Gut

authors： Spiller RC,Trotman IF,Adrian TE,Bloom SR,Misiewicz JJ,Silk DB

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Although Helicobacter pylori has been implicated in the pathogenesis of gastric mucosa associated lymphoid tissue (MALT) and MALT lymphoma, it is not known how it may trigger these lesions and whether there is an identifiable pre-neoplastic stage. AIMS:To investigate the relation between MALT, H pylori infe...

journal_title：Gut

authors： Sorrentino D,Ferraccioli GF,DeVita S,Avellini C,Beltrami CA,Labombarda A,Bernardis V,De Biase F,Trevisi A,Pivetta B,Boiocchi M,Bartoli E

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Concordance rates in siblings and twins provide strong evidence that genetic susceptibility is important in the pathogenesis of inflammatory bowel disease. The number and identity of susceptibility genes is largely uncertain. Cytokine genes are attractive candidate loci. AIMS:To study allelic frequencies of...

journal_title：Gut

authors： Louis E,Satsangi J,Roussomoustakaki M,Parkes M,Fanning G,Welsh K,Jewell D

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to compare azathioprine versus mesalazine tablets for the prevention of clinical recurrence in patients with postoperative Crohn's disease (CD) with moderate or severe endoscopic recurrence. METHODS:This was a 1 year, double-blind, double-dummy, randomised study which took place in 2...

journal_title：Gut

authors： Reinisch W,Angelberger S,Petritsch W,Shonova O,Lukas M,Bar-Meir S,Teml A,Schaeffeler E,Schwab M,Dilger K,Greinwald R,Mueller R,Stange EF,Herrlinger KR,International AZT-2 Study Group.

更新日期：2010-06-01 00:00:00

abstract：:This study reports on a group of 20 patients with an initial diagnosis of primary biliary cirrhosis (PBC) whose serum tested negative for antimitochondrial antibodies by immunofluorescence. All had a clinical history compatible with primary biliary cirrhosis, and results of biochemical, histological, and radiological ...

journal_title：Gut

authors： Michieletti P,Wanless IR,Katz A,Scheuer PJ,Yeaman SJ,Bassendine MF,Palmer JM,Heathcote EJ

更新日期：1994-02-01 00:00:00

abstract：:The extent to which defects in protein synthesis occurred in an experimental indomethacin induced rat model of nonsteroidal enteropathy has been examined. Male rats (nine) were fed indomethacin (8 mg/kg/day) for three days mixed with a powdered form of chow. The control group of rats (nine) were fed the same diet for ...

journal_title：Gut

authors： Banerjee AK,Marway JS,Preedy VR,Peters TJ

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Oligodeoxynucleotides (ODNs) containing unmethylated cytosine-guanosine (CpG) sequence motifs constitute the immunostimulatory components of bacterial DNA which potently activate innate immunity. Administration of CpG-ODNs before the onset of experimental colitis prevents intestinal inflammation by induction...

journal_title：Gut

authors： Hofmann C,Dunger N,Grunwald N,Hämmerling GJ,Hoffmann P,Schölmerich J,Falk W,Obermeier F

更新日期：2010-10-01 00:00:00

abstract：:Pectin has been shown to minimise the fall in blood glucose seen in patients who are troubled by hypoglycaemia attacks after gastric surgery. We therefore performed 50 g glucose tolerance tests with and without 14.5 g pectin on 11 post-gastric surgery patients. After pectin, the high postprandial levels of glucose, in...

journal_title：Gut

authors： Jenkins DJ,Bloom SR,Albuquerque RH,Leeds AR,Sarson DL,Metz GL,Alberti KG

更新日期：1980-07-01 00:00:00

abstract：OBJECTIVE:Assessment of disease extension and activity is crucial to guide treatment in Crohn's disease. The objective of the current cross-sectional study was to determine the accuracy of MR for this assessment. DESIGN:50 patients with clinically active (n = 35) or inactive (n = 15) Crohn's disease underwent ileocolo...

journal_title：Gut

authors： Rimola J,Rodriguez S,García-Bosch O,Ordás I,Ayala E,Aceituno M,Pellisé M,Ayuso C,Ricart E,Donoso L,Panés J

更新日期：2009-08-01 00:00:00

abstract：:We report two patients with periampullary cysts associated with recurrent attacks of acute pancreatitis. In both patients the diagnosis was made preoperatively by upper gastrointestinal endoscopy and ERCP, which was also useful in determining the relationship of the cysts to the biliary and pancreatic ductal systems. ...

journal_title：Gut

authors： Kalvaria I,Bornman PC,Girdwood AH,Marks IN

更新日期：1987-03-01 00:00:00