How well does stool form reflect colonic transit?

abstract：:Intravenous cholangiograms were performed on 100 unselected nonicteric patients using methylglucamine ioglycamide (Biligram). Fifty patients received 10.5 g of contrast medium and 50 received 5.25 g of medium. The contrast medium was injected evenly over five minutes. Side effects were recorded in only 13% of patients...

journal_title：Gut

authors： Parkin GJ,Herlinger H

更新日期：1974-04-01 00:00:00

abstract：:Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in an end-stage biliary cirrhosis. Both genetic and environmental influences are...

journal_title：Gut

authors： Hirschfield GM,Dyson JK,Alexander GJM,Chapman MH,Collier J,Hübscher S,Patanwala I,Pereira SP,Thain C,Thorburn D,Tiniakos D,Walmsley M,Webster G,Jones DEJ

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Emerging evidence suggests that highly treatment-resistant tumour-initiating cells (TICs) play a central role in the pathogenesis of pancreatic cancer. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered to be a novel anticancer agent; however, recent studies have shown th...

journal_title：Gut

authors： Kallifatidis G,Rausch V,Baumann B,Apel A,Beckermann BM,Groth A,Mattern J,Li Z,Kolb A,Moldenhauer G,Altevogt P,Wirth T,Werner J,Schemmer P,Büchler MW,Salnikov AV,Herr I

更新日期：2009-07-01 00:00:00

abstract：:Fourteen apparently healthy patients with ileostomies were found to be depleted of total exchangeable sodium and potassium, but had normal serum electrolyte concentrations and normal extracellular fluid and total body water volumes. The low exchangeable sodium and potassiums were thus primarily due to depletion of the...

journal_title：Gut

authors： Turnberg LA,Morris AI,Hawker PC,Herman KJ,Shields RA,Horth CE

更新日期：1978-06-01 00:00:00

abstract：OBJECTIVE:The complex genetic aetiology underlying irritable bowel syndrome (IBS) needs to be assessed in large-scale genetic studies. Two independent IBS cohorts were genotyped to assess whether genetic variability in immune, neuronal and barrier integrity genes is associated with IBS. DESIGN:384 single nucleotide po...

journal_title：Gut

authors： Wouters MM,Lambrechts D,Knapp M,Cleynen I,Whorwell P,Agréus L,Dlugosz A,Schmidt PT,Halfvarson J,Simrén M,Ohlsson B,Karling P,Van Wanrooy S,Mondelaers S,Vermeire S,Lindberg G,Spiller R,Dukes G,D'Amato M,Boeckxstaens

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Norovirus infection is the most frequent cause of infectious diarrhoea in the western world. This study aimed to characterise functionally and histomorphologically the diseased duodenum in human biopsies. METHODS:Norovirus infection was diagnosed by the Kaplan criteria and confirmed by PCR of stool samples....

journal_title：Gut

authors： Troeger H,Loddenkemper C,Schneider T,Schreier E,Epple HJ,Zeitz M,Fromm M,Schulzke JD

更新日期：2009-08-01 00:00:00

abstract：:Ileal permeability to different sized polyethyleneglycols (590-942 dalton PEG) was investigated peroperatively in 11 patients with Crohn's disease and seven with colonic carcinoma. A 15 cm ileal segment was converted into a tied loop, in which the PEG's were deposited. Absorption from the ileal segment was then measur...

journal_title：Gut

authors： Olaison G,Leandersson P,Sjödahl R,Tagesson C

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. The geographical prevalence varies considerably in different countries and Scotland is regarded as an area of low risk for the disease. AIMS:To assess the association between chronic hepatitis C infection (HCV) and HCC in a popul...

journal_title：Gut

authors： Haydon GH,Jarvis LM,Simmonds P,Harrison DJ,Garden OJ,Hayes PC

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Opioids are increasingly prescribed in the West and have deleterious GI consequences. Pharmacological therapies to treat opioid-induced constipation (OIC) are available, but their relative efficacy is unclear. We performed a systematic review and network meta-analysis to address this deficit in current knowle...

journal_title：Gut

authors： Luthra P,Burr NE,Brenner DM,Ford AC

更新日期：2019-03-01 00:00:00

abstract：:The responses to deglutition of the lower oesophageal high pressure zone were studied in 13 healthy subjects. The recording assembly included three perfused pressure recording catheters, whose recording orifices were at the same axial level, and a more distally situated pH electrode. Relaxation and contraction progres...

journal_title：Gut

authors： Kaye MD,Showalter JP

更新日期：1972-05-01 00:00:00

abstract：BACKGROUND:Studies on intestinal T cell clones from the mucosa of patients with coeliac disease have led to the identification of immunogenic gliadin epitopes. One is HLA-DQ8 restricted, its recognition by T cells being increased by introduction of negatively charged residues operated by tissue transglutaminase. AIM:T...

journal_title：Gut

authors： Mazzarella G,Maglio M,Paparo F,Nardone G,Stefanile R,Greco L,van de Wal Y,Kooy Y,Koning F,Auricchio S,Troncone R

更新日期：2003-01-01 00:00:00

abstract：:The plasma clearance and the liver uptake of intravenously administered (64)Cu were significantly impaired in four patients with Wilson's disease. These defects were unlikely to be simply expressions of the high liver copper concentration as the plasma clearance and hepatic uptake of (64)Cu were normal in four patient...

journal_title：Gut

authors： Smallwood RA,McIlveen B,Rosenoer VM,Sherlock S

更新日期：1971-02-01 00:00:00

abstract：:Prostaglandins (PGs) are synthesised by gastric mucosa, and have been shown to inhibit gastric acid secretion and ulcer formation in man and experimental animals. Recently exogenous PGs, mainly of the E group, have been used for the treatment of peptic ulcer disease. We therefore searched for a drug that would stimula...

journal_title：Gut

authors： Ligumsky M,Rachmilewitz D,Zor U

更新日期：1979-10-01 00:00:00

abstract：:The free primary amines present in the faeces of 44 infants (1-18 months) with gastroenteritis have been examined by field desorption mass spectrometry of the lactone form of their fluorescamine derivatives without their prior separation. p-Tyramine, 2-phenylethylamine, the diamines, putrescine and cadaverine and seve...

journal_title：Gut

authors： Murray KE,Adams RF,Earl JW,Shaw KJ

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Six to 12 months of ingestion of moderate amounts of oats does not have a harmful effect in adult patients with coeliac disease. As the safety of long term intake of oats in coeliac patients is not known, we continued our previous 6-12 month study for five years. AIM:To assess the safety of long term ingest...

journal_title：Gut

authors： Janatuinen EK,Kemppainen TA,Julkunen RJ,Kosma VM,Mäki M,Heikkinen M,Uusitupa MI

更新日期：2002-03-01 00:00:00

abstract：:Measurements of cell proliferation can be used as biomarkers of preneoplastic change. In this study, two immunocytochemical methods that measure different components of the cell cycle were compared to assess cell proliferation on biopsy samples from human colonic mucosa. These methods are based on a monoclonal antibod...

journal_title：Gut

authors： Weisgerber UM,Boeing H,Nemitz R,Raedsch R,Waldherr R

更新日期：1993-11-01 00:00:00

abstract：:Transiliac biopsies from 34 female patients with corticosteroid treated chronic active hepatitis have been examined to determine the contributions made by decreased bone formation and increased bone resorption to bone loss associated with this condition and to determine the structural basis of the bone loss. Mean wall...

journal_title：Gut

authors： Stellon AJ,Webb A,Compston JE

更新日期：1988-03-01 00:00:00

abstract：:Plasminogen activator activity was studied in bile and perfusate during extracorporeal pig liver perfusion. Plasminogen activator activity in bile was up to 58 times greater than in perfusate. A high level of plasminogen activator activity in bile was also found after the addition of urokinase to the perfusate. These ...

journal_title：Gut

authors： Jedrychowski A,Parbhoo SP,Hillenbrand P

更新日期：1972-01-01 00:00:00

abstract：:Probiotic administration may exert a protective effect in colitis by preventing mucosal barrier disruption and influencing the extent of mucosal injury. ...

journal_title：Gut

authors： Gionchetti P,Lammers KM,Rizzello F,Campieri M

更新日期：2005-07-01 00:00:00

abstract：:Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes. There are several approaches to liver biopsy but predominantly percutaneous or transvenous approaches are used. A wide choice of needles ...

journal_title：Gut

authors： Neuberger J,Patel J,Caldwell H,Davies S,Hebditch V,Hollywood C,Hubscher S,Karkhanis S,Lester W,Roslund N,West R,Wyatt JI,Heydtmann M

更新日期：2020-08-01 00:00:00

abstract：:Options for managing the common bile duct during laparoscopic cholecystectomy include routine peroperative cholangiography and selected preoperative endoscopic retrograde cholangiopancreatography (ERCP). The use of these methods was reviewed in 350 patients with symptomatic gall stones referred for laparoscopic cholec...

journal_title：Gut

authors： Hainsworth PJ,Rhodes M,Gompertz RH,Armstrong CP,Lennard TW

更新日期：1994-07-01 00:00:00

abstract：:We investigated the distribution of the collagen band in 33 patients with collagenous colitis to estimate the likelihood of the disease being diagnosed in biopsy specimens from the left side of the colon, such as those obtained using flexible sigmoidoscopy. To be included in this study patients had a subepithelial col...

journal_title：Gut

authors： Tanaka M,Mazzoleni G,Riddell RH

更新日期：1992-01-01 00:00:00

abstract：:This study compares the gastroprotective effects of colloidal bismuth subcitrate (De-Nol) with those of sucralfate and a methylated analogue of prostaglandin E2 (PGE2) against acute gastric lesions induced by acidified aspirin and absolute ethanol in rats. Both De-Nol and sucralfate given orally prevented dose depende...

journal_title：Gut

authors： Konturek SJ,Radecki T,Piastucki I,Brzozowski T,Drozdowicz D

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Gastrokine 1 (GKN1) is a stomach-specific protein that is normally expressed in gastric mucosa but not in primary tumours and cell lines. Based on this evidence, it was presumed that GKN1 might play a role in gastric cancer development; however, its function and molecular mechanism are not clear. A ...

journal_title：Gut

authors： Xing R,Li W,Cui J,Zhang J,Kang B,Wang Y,Wang Z,Liu S,Lu Y

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Dyspepsia and irritable bowel syndrome are suitable conditions for assessment of quality of life. Their similarities justify the elaboration of a single specific questionnaire for the two conditions. AIMS:To examine the process leading to the validation of the psychometric properties of the functional diges...

journal_title：Gut

authors： Chassany O,Marquis P,Scherrer B,Read NW,Finger T,Bergmann JF,Fraitag B,Geneve J,Caulin C

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND AIM:Accumulation and infiltration by neutrophil granulocytes is a prominent feature in the local inflammatory process in ulcerative colitis (UC). The present study was performed to evaluate human neutrophil lipocalin (HNL) as a specific neutrophil marker in the inflamed lesions of the colon and rectum in...

journal_title：Gut

authors： Carlson M,Raab Y,Sevéus L,Xu S,Hällgren R,Venge P

更新日期：2002-04-01 00:00:00

abstract：:Of 279 patients admitted to a specialist unit with acute pancreatitis, 210 were admitted directly and 69 were transferred for treatment of local or systemic complications. Outcome was assessed in terms of mortality and morbidity and in relation to aetiology, predicted severity of disease (modified Glasgow score), orga...

journal_title：Gut

authors： de Beaux AC,Palmer KR,Carter DC

更新日期：1995-07-01 00:00:00

abstract：:The aims of the present study were to determine the relative amplitudes of intragastric motor responses evoked by different vagal branches and to establish whether the effects of acute or chronic vagotomy could be predicted from these data. Intragastric pressure responses to electrical stimulation of the vagus were me...

journal_title：Gut

authors： Andrews PL,Lawes IN,Bower AJ

更新日期：1980-10-01 00:00:00

abstract：:Marked decreases in 24-hour Heidenhain pouch secretion, lasting from nine to 18 days, were observed in five mongrel bitches during periods of naturally occurring oestrus. Neither oophorectomy nor control celiotomy caused significant change in Heidenhain pouch secretion in bitches who were not experiencing oestrus. The...

journal_title：Gut

authors： Landor JH,Wild RA

更新日期：1970-10-01 00:00:00

abstract：:The mucosal potential difference in the body of the stomach was measured in 18 patients with gastric ulcers, five with gastritis, and three with pernicious anaemia. The results were compared with those of 12 normal volunteers. Significantly lower than normal levels were found in the groups of patients with gastric ulc...

journal_title：Gut

authors： Hossenbocus A,Fitzpatrick P,Colin-Jones DG

更新日期：1976-12-01 00:00:00