Use and abuse of hydrogen breath tests.

abstract：:The endothelins are a group of three related peptides with two receptor subtypes, ET(A) and ET(B). Following the discovery of endothelin 1 as a potent vasoconstrictor, there has been intense interest in the role of endothelin on vascular function in liver disease. Speculation on the role of endothelin in the pathogene...

journal_title：Gut

authors： Moore K

更新日期：2004-02-01 00:00:00

abstract：:A chronic colitis has been induced in rabbits having many of the histological features of human ulcerative colitis. Animals were first immunised with the common enterobacterial antigen of Kunin and haemagglutinating antibodies demonstrated in high titre. An immune complex colitis was then established by the injection ...

journal_title：Gut

authors： Mee AS,McLaughlin JE,Hodgson HJ,Jewell DP

更新日期：1979-01-01 00:00:00

abstract：:The prevalence of metabolic disease in a population of 68 postgastrectomy patients was assessed using histomorphometric evaluation of transiliac bone biopsy specimens after tetracycline double labelling. Trabecular bone volume was significantly lower in the postgastrectomy group (p less than 0.01): 62% of the patients...

journal_title：Gut

authors： Bisballe S,Eriksen EF,Melsen F,Mosekilde L,Sørensen OH,Hessov I

更新日期：1991-11-01 00:00:00

abstract：:In a randomised clinical trial, patients with moderately active Crohn's disease received either prednisolone 0.5 mg/kg/day plus a normal diet, or an elemental diet plus oral framycetin, colistin and nystatin. Patients were assessed using the Crohn's disease activity index (CDAI), ESR, and faecal granulocyte excretion ...

journal_title：Gut

authors： Saverymuttu S,Hodgson HJ,Chadwick VS

更新日期：1985-10-01 00:00:00

abstract：:A manometric method was developed to study the motor activity in the unprepared human colon, and the results in eight healthy subjects were compared with those obtained in the same subjects after bowel cleansing with a non-absorbable solution containing polyethylene glycol 4000 (PEG). A tube assembly (4.5 m long, 12 l...

journal_title：Gut

authors： Lémann M,Flourié B,Picon L,Coffin B,Jian R,Rambaud JC

更新日期：1995-11-01 00:00:00

abstract：:Because of the increasing use of immunosuppressive and biological drugs, the occurrence of opportunistic infections has become a key safety issue for patients with inflammatory bowel disease (IBD). Consequently, improvement of healthcare workers' knowledge of this domain is urgent. In this review, the preventive measu...

journal_title：Gut

authors： Viget N,Vernier-Massouille G,Salmon-Ceron D,Yazdanpanah Y,Colombel JF

更新日期：2008-04-01 00:00:00

abstract：:Gastroparesis is defined by the presence of delayed gastric emptying (GE) in the absence of mechanical obstruction. Symptoms that have been attributed to gastroparesis include postprandial fullness, early satiation nausea and vomiting. Gastroprokinetic drugs are the preferred treatment option. A number of problems wit...

journal_title：Gut

authors： Stanghellini V,Tack J

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:In transplant recipients with choledococholedocostomy (CDCD), endoscopic retrograde cholangiopancreatography (ERCP) remains the gold standard for the diagnosis of biliary leak or strictures. Transabdominal ultrasonography (TAUS) has been used to screen patients with suspected biliary tract complications, pri...

journal_title：Gut

authors： Hussaini SH,Sheridan MB,Davies M

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Despite the recent discovery of four genes responsible for up to 90% of all cases of hereditary non-polyposis colorectal cancer (HNPCC), there will still be families in whom predictive testing is not possible. A phenotypic biomarker would therefore be useful. An upwards shift of the proliferative compartment...

journal_title：Gut

authors： Green SE,Chapman P,Burn J,Burt AD,Bennett M,Appleton DR,Varma JS,Mathers JC

更新日期：1998-07-01 00:00:00

abstract：:Nodular regenerative hyperplasia of the liver usually presents with signs of portal hypertension with little evidence of obvious liver disease. We report a 47 year old man who presented with clinical signs of decompensated cirrhosis, recurrent encephalopathy, and tense ascites but at liver transplant was found to have...

journal_title：Gut

authors： McDonald JA,Painter DM,Gallagher ND,McCaughan GW

更新日期：1990-06-01 00:00:00

abstract：:Calcium in milk products stimulates gastric acid secretion and inhibits the cytolytic activity of intestinal contents. Based on these effects, it was hypothesised that calcium might lessen the severity of food borne intestinal infections. The possible differential effects of a low calcium milk and normal milk products...

journal_title：Gut

authors： Bovee-Oudenhoven I,Termont D,Dekker R,Van der Meer R

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:Helicobacter pylori (Hp) is a major risk factor for gastric cancer (GC). Hp promotes DNA damage and proteasomal degradation of p53, the guardian of genome stability. Hp reduces the expression of the transcription factor USF1 shown to stabilise p53 in response to genotoxic stress. We investigated whether Hp-me...

journal_title：Gut

authors： Costa L,Corre S,Michel V,Le Luel K,Fernandes J,Ziveri J,Jouvion G,Danckaert A,Mouchet N,Da Silva Barreira D,Torres J,Camorlinga M,D'Elios MM,Fiette L,De Reuse H,Galibert MD,Touati E

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The detection of hepatocellular cancers (HCC) is a major role of preoperative imaging in patients with end stage liver disease being considered for orthotopic liver transplantation (OLT). AIMS:To assess the sensitivity of iodised oil computed tomography (IOCT). PATIENTS AND METHODS:A prospective evaluation...

journal_title：Gut

authors： Saada J,Bhattacharya S,Dhillon AP,Dick R,Burroughs AK,Rolles K,Davidson BR

更新日期：1997-09-01 00:00:00

abstract：:The mechanism by which intragastric balloons induce weight loss is not known, although they may act simply by reducing the amount of food needed to induce satiety. The knowledge that a balloon is present may influence the patients' eating patterns and reduce caloric intake and weight. In order to test whether the ball...

journal_title：Gut

authors： Ramhamadany EM,Fowler J,Baird IM

更新日期：1989-08-01 00:00:00

abstract：:Blood ethanol concentrations after separate oral dosing and intravenous infusion of ethanol (0.15 g/kg) were measured in 16 control subjects and 13 subjects treated with ranitidine. All subjects underwent routine upper gastrointestinal endoscopy. Peak blood ethanol concentrations, and area under the blood ethanol/time...

journal_title：Gut

authors： Brown AS,Fiaterone JR,Day CP,Bennett MK,Kelly PJ,James OF

更新日期：1995-09-01 00:00:00

abstract：:The generation of suppression by concanavalin A in peripheral blood mononuclear cells in treated and untreated coeliac subjects using an in vitro assay was found to be significantly increased when compared with controls. The response of peripheral blood mononuclear cells to the plant mitogen concanavalin A (con A) was...

journal_title：Gut

authors： O'Farrelly C,McKeever U,Feighery C,Weir DG

更新日期：1984-06-01 00:00:00

abstract：:Six of 25 renal transplant recipients had a duodenal ulcer at endoscopy. Histamine concentration and the activity of histamine methyltransferase, the degrading enzyme of histamine, were measured in gastric mucosal biopsies obtained at endoscopy and compared with patients with duodenal ulcer but not undergoing transpla...

journal_title：Gut

authors： Timoney AG,Man WK,Spencer J,Taylor H,Williams G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Hypersensitivity of gastric afferent pathways may play an aetiological role in symptoms of functional dyspepsia. AIMS:To determine whether patients with severe organic dyspepsia (associated with tissue irritation/injury) and those with functional dyspepsia (no detectable tissue irritation) differ in their p...

journal_title：Gut

authors： Mertz H,Fullerton S,Naliboff B,Mayer EA

更新日期：1998-06-01 00:00:00

abstract：:Patients with chronic active hepatitis or alcoholic cirrhosis have serum antibodies to many more serotypes of Escherichia coli than do patients with primary biliary cirrhosis or cryptogenic cirrhosis, or normal controls. They also have antibodies against more serotypes than cirrhotic patients with a portacaval shunt. ...

journal_title：Gut

authors： Simjee AE,Hamilton-Miller JM,Thomas HC,Brumfitt W,Sherlock S

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:Contrary to the long-standing prerequisite of inducing selective (ie, bifidogenic) effects, recent findings suggest that prebiotic interventions lead to ecosystem-wide microbiota shifts. Yet, a comprehensive characterisation of this process is still lacking. Here, we apply 16S rDNA microbiota profiling and ma...

journal_title：Gut

authors： Vandeputte D,Falony G,Vieira-Silva S,Wang J,Sailer M,Theis S,Verbeke K,Raes J

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Increased expression of proinflammatory cytokines, including tumour necrosis factor alpha, interleukin 6, and interferon gamma, as well as activation of proinflammatory signalling molecules such as nuclear factor kappa B, is characteristic of inflammatory bowel disease (IBD). AIMS:To investigate expression ...

journal_title：Gut

authors： Schreiber S,Rosenstiel P,Hampe J,Nikolaus S,Groessner B,Schottelius A,Kühbacher T,Hämling J,Fölsch UR,Seegert D

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Studies on intestinal T cell clones from the mucosa of patients with coeliac disease have led to the identification of immunogenic gliadin epitopes. One is HLA-DQ8 restricted, its recognition by T cells being increased by introduction of negatively charged residues operated by tissue transglutaminase. AIM:T...

journal_title：Gut

authors： Mazzarella G,Maglio M,Paparo F,Nardone G,Stefanile R,Greco L,van de Wal Y,Kooy Y,Koning F,Auricchio S,Troncone R

更新日期：2003-01-01 00:00:00

abstract：:In man, the main pancreatic duct is normally derived from ventral and dorsal embryological buds of the pancreas. In a minority of people, failure of fusion of the two buds results in separate drainage of the dorsal and ventral pancreas, so that the accessory duct provides the main drainage for the gland. Patients with...

journal_title：Gut

authors： Mitchell CJ,Lintott DJ,Ruddell WS,Losowsky MS,Axon AT

更新日期：1979-12-01 00:00:00

abstract：:Seventeen patients with proven systemic sclerosis had a peroral jejunal biopsy performed. Four biopsies were regarded as showing abnormalities, which were mostly confined to the deeper structures, although in two there was a minimal degree of villous atrophy without epithelial cell changes. Passive intestinal permeabi...

journal_title：Gut

authors： Cobden I,Rothwell J,Axon AT,Dixon MF,Lintott DJ,Rowell NR

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:The role of the recently discovered GB virus C (GBV-C)/hepatitis G virus in fulminant hepatic failure (FHF) has been debated. Although GBV-C RNA has been detected in many cases of FHF, recent data suggest that the relation between GBV-C and FHF may be accidental. AIMS:To retrospectively investigate the poss...

journal_title：Gut

authors： Halasz R,Barkholt L,Lara C,Hultgren C,Ando Y,Broomé U,Fischler B,Nemeth A,Ericzon BG,Sönnerborg A,Sällberg M

更新日期：1999-02-01 00:00:00

abstract：:A dialysis method for the study of intestinal absorption is described. Its use has been assessed in animals and normal human subjects and it has been applied to the measurement of rectal transport of sodium and water.When the luminal solution was of high sodium concentration (145 m-equiv/1), the sodium influx rate (lu...

journal_title：Gut

authors： Edmonds CJ

更新日期：1971-05-01 00:00:00

abstract：:To investigate the mechanisms underlying the hepatotoxicity induced by methyl dopa, we have examined sera from nine patients with liver damage following the use of the drug for evidence of sensitisation to drug altered liver cell membrane antigens using both immunofluorescence and antibody dependent cell mediated cyto...

journal_title：Gut

authors： Neuberger J,Kenna JG,Nouri Aria K,Williams R

更新日期：1985-11-01 00:00:00

abstract：:A previous cohort study suggested that there might be an association between use of cimetidine and motor neurone disease. The Oxford Record Linkage Study was used to explore this hypothesis. In the analysis the presence of a peptic ulcer in patients after 1976 was taken as a proxy for cimetidine (and ranitidine) use. ...

journal_title：Gut

authors： Vessey MP,Goldacre MJ,Seagroatt V,Yeates D

更新日期：1993-12-01 00:00:00

abstract：:A retrospective study was undertaken to investigate how endoscopies yielding positive findings differ a priori from those yielding negative findings: and how those judged 'helpful' (in the sense of influencing management) differ a priori from those judged 'unhelpful'. A total of 483 patients undergoing endoscopy was s...

journal_title：Gut

authors： Naji SA,Brunt PW,Hagen S,Mowat NA,Russell IT,Sinclair TS,Tang TM

更新日期：1993-02-01 00:00:00

abstract：:The carrier rate of hepatitis B virus (HBV) in black Africans averages 10.4% throughout the continent. Even within each country, however, there may be wide variations. HBV carriage in black Africans is largely established in early childhood, mostly through horizontal transmission. Perinatal transmission also occurs bu...

journal_title：Gut

authors： Kew MC

更新日期：1996-01-01 00:00:00