Osteopenia and osteomalacia after gastrectomy: interrelations between biochemical markers of bone remodelling, vitamin D metabolites, and bone histomorphometry.

abstract：BACKGROUND:Hepatic stellate cells (HSCs) are a major fibrogenic cell type that contributes to collagen accumulation during chronic liver disease. With increasing interest in developing antifibrotic therapies, there is a need for cell lines that preserve the in vivo phenotype of human HSCs to elucidate pathways of human...

journal_title：Gut

authors： Xu L,Hui AY,Albanis E,Arthur MJ,O'Byrne SM,Blaner WS,Mukherjee P,Friedman SL,Eng FJ

更新日期：2005-01-01 00:00:00

abstract：:A patient presented with pruritus and recent elevation of aminotransferases. The case fulfilled most of the criteria for the diagnosis of autoimmune hepatitis and achieved clinical and complete biochemical response to steroid therapy. However, the liver biopsy specimen revealed an unusual histological pattern consisti...

journal_title：Gut

authors： Te HS,Koukoulis G,Ganger DR

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Based on equivocal clinical data, intravenous antioxidant therapy has been used for the treatment of severe acute pancreatitis. To date there is no randomised comparison of this therapy in severe acute pancreatitis. METHODS:We conducted a randomised, double blind, placebo controlled trial of intravenous ant...

journal_title：Gut

authors： Siriwardena AK,Mason JM,Balachandra S,Bagul A,Galloway S,Formela L,Hardman JG,Jamdar S

更新日期：2007-10-01 00:00:00

abstract：:Increased concentrations of the soluble form of the interleukin 2 receptor have been observed in the sera of Crohn's disease and ulcerative colitis patients. In this study we have observed the spontaneous release of soluble interleukin 2 receptor by unstimulated, isolated normal and inflammatory bowel disease colonic ...

journal_title：Gut

authors： Schreiber S,Raedler A,Conn AR,Rombeau JL,MacDermott RP

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:To identify a causal mechanism responsible for the enhancement of insulin resistance and hyperglycaemia following periodontitis in mice fed a fat-enriched diet. DESIGN:We set-up a unique animal model of periodontitis in C57Bl/6 female mice by infecting the periodontal tissue with specific and alive pathogens...

journal_title：Gut

authors： Blasco-Baque V,Garidou L,Pomié C,Escoula Q,Loubieres P,Le Gall-David S,Lemaitre M,Nicolas S,Klopp P,Waget A,Azalbert V,Colom A,Bonnaure-Mallet M,Kemoun P,Serino M,Burcelin R

更新日期：2017-05-01 00:00:00

abstract：:Gastric antral vascular ectasia ('water melon stomach') is a poorly documented cause of occult upper gastrointestinal blood loss. We describe a case which emphasises the clinical and pathological difficulties that can be encountered in making this elusive diagnosis. ...

journal_title：Gut

authors： Gouldesbrough DR,Pell AC

更新日期：1991-08-01 00:00:00

abstract：:The distribution of mucosal PGE2-like activity was determined by bioassay technique in the body and antrum of the stomach and in the duodenum of healthy subjects and duodenal ulcer patients before and after administration of aspirin, paracetamol, or histamine. In healthy subjects, the oxyntic, antral and duodenal muco...

journal_title：Gut

authors： Konturek SJ,Obtulowicz W,Sito E,Oleksy J,Wilkon S,Kiec-Dembinska A

更新日期：1981-04-01 00:00:00

abstract：:Thirty male patients (27 homosexual) with biopsy proven chronic active hepatitis B were randomised to receive lymphoblastoid interferon (Wellferon) or no treatment. All patients were HBeAg positive and had continuing viral replication. Patients receiving treatment were given a single daily intramuscular injection of i...

journal_title：Gut

authors： Anderson MG,Harrison TJ,Alexander G,Zuckerman AJ,Murray-Lyon IM

更新日期：1987-05-01 00:00:00

abstract：:Based on short recordings, the rectum has been shown to have contractions with a frequency of five to 10 cycles per minute and slow contractions at three cycles per minute. To define anorectal motility over a prolonged period of time, we have studied 12 healthy volunteers using a fine pressure sensitive anorectal prob...

journal_title：Gut

authors： Kumar D,Williams NS,Waldron D,Wingate DL

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The authors have previously isolated a putative oncogene, eukaryotic initiation factor 5A2 (EIF5A2) from 3q26. In this study, EIF5A2 was characterised for its role in colorectal carcinoma (CRC) aggressiveness and underlying molecular mechanisms. METHODS:The expression dynamics of EIF5A2 were examin...

journal_title：Gut

authors： Zhu W,Cai MY,Tong ZT,Dong SS,Mai SJ,Liao YJ,Bian XW,Lin MC,Kung HF,Zeng YX,Guan XY,Xie D

更新日期：2012-04-01 00:00:00

abstract：:On the basis of circumstantial clinical and experimental evidence, it has been suggested that enteroglucagon (EG) may act as an enterotrophic factor. This study was undertaken to evaluate the effects of long term in vivo immunoneutralisation of EG, using monoclonal antibodies to EG, on the hyperplastic ileal response ...

journal_title：Gut

authors： Gregor M,Menge H,Stössel R,Riecken EO

更新日期：1987-01-01 00:00:00

abstract：:In a prospective survey positive antimitochondrial antibodies have been detected in 69/4200 (1.64%) of all sera submitted to a routine immunology laboratory. Of the 69, only nine patients had uniquivocal primary biliary cirrhosis, six others had chronic active hepatitis, 10 had abnormal liver function tests without ev...

journal_title：Gut

authors： Triger DR,Charlton CA,Ward AM

更新日期：1982-10-01 00:00:00

abstract：:Gastroparesis is defined by the presence of delayed gastric emptying (GE) in the absence of mechanical obstruction. Symptoms that have been attributed to gastroparesis include postprandial fullness, early satiation nausea and vomiting. Gastroprokinetic drugs are the preferred treatment option. A number of problems wit...

journal_title：Gut

authors： Stanghellini V,Tack J

更新日期：2014-12-01 00:00:00

abstract：:The finding in primary IgA nephropathy of increased levels of IgA to food antigens and particularly to gliadin prompted the hypothesis that a subgroup of these patients may have latent coeliac disease. The observation that gliadin may experimentally induce IgA mesangial deposits supported this hypothesis. We evaluated...

journal_title：Gut

authors： Sategna-Guidetti C,Ferfoglia G,Bruno M,Pulitano R,Roccatello D,Amore A,Coppo R

更新日期：1992-04-01 00:00:00

abstract：:Sex differences exist in the site specific incidences of colorectal cancer. The increased incidence of colonic cancer in women with breast cancer and the protective effect of increasing parity suggest a role for sex hormones. To explore the molecular basis, the expression of messenger RNA for oestrogen and progesteron...

journal_title：Gut

authors： Singh S,Sheppard MC,Langman MJ

更新日期：1993-05-01 00:00:00

abstract：:The nervous system in the intestine controls motility, secretion, sensory perception, and immune function. Peptidergic neurones with neurotransmitters such as substance P and nerve growth factors have been the main focus of neuroimmunomodulation research in the gut. This review summarises the present knowledge concern...

journal_title：Gut

authors： Straub RH,Wiest R,Strauch UG,Härle P,Schölmerich J

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND/AIMS:Transjugular intrahepatic portosystemic stent shunt (TIPSS) is effective in the prevention of variceal rebleeding but requires invasive portographic follow up. This randomised controlled trial aims to test the hypothesis that combining variceal band ligation (VBL) with TIPSS can obviate the need for lon...

journal_title：Gut

authors： Tripathi D,Lui HF,Helmy A,Dabos K,Forrest E,Stanley AJ,Jalan R,Redhead DN,Hayes PC

更新日期：2004-03-01 00:00:00

abstract：:A histochemical study of conjugated and total bilirubin was made on liver biopsies of 150 patients. Three types of cholestasis were defined: type I, characterized by the presence of intracellular pigment granules in the hepatocytes; type II, showing intracellular granules and extracellular thrombi (this group may be s...

journal_title：Gut

authors： Desmet VJ,Bullens AM,De Groote J

更新日期：1970-06-01 00:00:00

abstract：:Alcohol tolerance has been studied in 10 patients after proximal gastric vagotomy and six patients after truncal vagotomy and antrectomy. No difference in alcohol tolerance was found before and after proximal gastric vagotomy, while an increased rate of absorption with higher blood levels of alcohol were found after t...

journal_title：Gut

authors： Moodie AF,Royston CM,Spencer J

更新日期：1975-12-01 00:00:00

abstract：OBJECTIVES:Oesophageal squamous cell carcinoma (OSCC) and adenocarcinoma (OAC) are distinct cancers in terms of a number of clinical and epidemiological characteristics, complicating the design of clinical trials and biomarker developments. We analysed 1048 oesophageal tumour-germline pairs from both subtypes, to chara...

journal_title：Gut

authors： Lin DC,Dinh HQ,Xie JJ,Mayakonda A,Silva TC,Jiang YY,Ding LW,He JZ,Xu XE,Hao JJ,Wang MR,Li C,Xu LY,Li EM,Berman BP,Phillip Koeffler H

更新日期：2018-10-01 00:00:00

abstract：:The prevalence of methane production in an adult population of 256 subjects was 41%, but it was significantly higher in females (49%), than males (33%). When the population was subdivided into ethnic groups. Caucasians (48%) and Black (45%) had significantly more methane producers than Orientals (24%) and Indians (32%...

journal_title：Gut

authors： Pitt P,de Bruijn KM,Beeching MF,Goldberg E,Blendis LM

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe inflammatory diseases, but the responsiveness of GI epithelial cells to bacterial stimulation remains unclear. DESIGN:We gene...

journal_title：Gut

authors： Kayisoglu O,Weiss F,Niklas C,Pierotti I,Pompaiah M,Wallaschek N,Germer CT,Wiegering A,Bartfeld S

更新日期：2020-06-22 00:00:00

abstract：:Because previous studies have suggested that red cell membrane sialic acid might be a determinant of survival in vivo, we examined the relationship between haemolysis, erythrocyte membrane sialic acid, and hepatic neuraminidase (sialidase) levels in experimental cholestatic jaundice in rats. Treatment of normal rat er...

journal_title：Gut

authors： Powell LW,LaMont JT,Isselbacher KJ

更新日期：1974-10-01 00:00:00

abstract：:The incidence of small intestinal colonization in unoperated duodenal ulcer patients was low and similar to that in the normal population. The majority of patients seven to 10 days following truncal vagotomy and drainage were colonized whereas none of a control group of patients following simple closure of a perforate...

journal_title：Gut

authors： Browning GG,Buchan KA,Mackay C

更新日期：1974-02-01 00:00:00

abstract：OBJECTIVES:Gastric cancer is strongly associated with Helicobacter pylori (H. pylori). We conducted a previous systematic review and meta-analysis that suggested eradication therapy reduced future incidence of gastric cancer, but effect size was uncertain, and there was no reduction in gastric cancer-related mortality....

journal_title：Gut

authors： Ford AC,Yuan Y,Moayyedi P

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:The risk of colorectal cancer after a previous negative colonoscopy is very low. Nevertheless, interval cancers occur. We aimed to assess the characteristics and predictors of interval cancers after negative colonoscopy. METHODS:A population-based case-control study was conducted in Southern Germany in 2003-...

journal_title：Gut

authors： Brenner H,Chang-Claude J,Seiler CM,Hoffmeister M

更新日期：2012-11-01 00:00:00

abstract：:These updated guidelines on the management of variceal haemorrhage have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines which this document supersedes were written in 2...

journal_title：Gut

authors： Tripathi D,Stanley AJ,Hayes PC,Patch D,Millson C,Mehrzad H,Austin A,Ferguson JW,Olliff SP,Hudson M,Christie JM,Clinical Services and Standards Committee of the British Society of Gastroenterology.

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Conventional colonoscopy (CC) is considered the reference standard for detection of colorectal neoplasia, but it can still miss a substantial number of adenomas. The use of a transparent plastic cap may improve colonic visualisation. Cap-assisted colonoscopy (CAC) was compared with CC for adenoma detection. S...

journal_title：Gut

authors： de Wijkerslooth TR,Stoop EM,Bossuyt PM,Mathus-Vliegen EM,Dees J,Tytgat KM,van Leerdam ME,Fockens P,Kuipers EJ,Dekker E

更新日期：2012-10-01 00:00:00

abstract：:Intraluminal manometric studies performed on 12 patients with chronic Chagas disease and megacolon without clinical or radiological abnormalities of the oesophagus showed no alteration in oesophageal physiology under basal conditions when compared with a control group of 30 healthy subjects. Oesophageal peristalsis wa...

journal_title：Gut

authors： Heitmann P,Espinoza J

更新日期：1969-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The authors' goal was to measure pH at the gastric surface (pH₀) to understand how acid secretion affects the repair of microscopic injury to the gastric epithelium. METHODS:Microscopic gastric damage was induced by laser light, during confocal/two-photon imaging of pH-sensitive dyes (Cl-NERF, BCEC...

journal_title：Gut

authors： Demitrack ES,Aihara E,Kenny S,Varro A,Montrose MH

更新日期：2012-06-01 00:00:00