Abstract:
:Introduction of chimeric transferrin-chloramphenicol acetyltransferase genes into transgenic mice provides a model by which modulation of the human transferrin gene may be studied in vivo. Iron injected into this mouse model decreases liver expression of the reporter enzyme in a manner analogous to its effect on plasma transferrin levels.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
doi
10.1111/j.1753-4887.1991.tb03029.xsubject
Has Abstractpub_date
1991-07-01 00:00:00pages
221-3issue
7eissn
0029-6643issn
1753-4887journal_volume
49pub_type
杂志文章,评审abstract::Mitochondria exert crucial physiological functions that create complex links among nutrition, health, and disease. While mitochondrial dysfunction with subsequent impairment of oxidative phosphorylation (OXPHOS) is the hallmark of the rare inherited OXPHOS diseases, OXPHOS dysfunction also plays a central role in the ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00363.x
更新日期:2011-02-01 00:00:00
abstract::Health claims for foods are permitted in an increasing number of countries, but there are very few studies evaluating their effect on purchase behavior and consumer health. There are significant differences between countries but, in general, consumers see health claims as useful; they prefer short, succinct wording ra...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2005.tb00382.x
更新日期:2005-07-01 00:00:00
abstract::Long-term metabolic studies indicate that over-feeding underfeeding to gain and lose body weight produce consistent increases and decreases in energy expenditure. These changes occur in both lean and obese subjects and cause deviations from the normal relationship between energy expenditure and metabolic body size. Th...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1995.tb05484.x
更新日期:1995-09-01 00:00:00
abstract::A recent randomized, double-blind, placebo-controlled trial found that protein supplementation improved recovery from femoral fractures in an elderly population. A 6-month course of protein supplementation (20 g/day, 5 days/week) improved serum prealbumin and insulin-like growth factor I (IGF-I) concentrations, minimi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01672.x
更新日期:1998-11-01 00:00:00
abstract::In 2017, an estimated 1 in every 4 (23%) children aged < 5 years were stunted worldwide. With slow progress in stunting reduction in many regions and the realization that a large proportion of stunting is not due to insufficient diet or diarrhea alone, it remains that other factors must explain continued growth falter...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuy068
更新日期:2019-04-01 00:00:00
abstract::Patients in the intensive care unit are at high risk of glutamine depletion and subsequent complications. Several controlled studies and a meta-analysis have concluded that glutamine supplementation has beneficial effects on the clinical outcome of critically ill and surgical patients. These results may be explained b...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2005.tb00123.x
更新日期:2005-02-01 00:00:00
abstract::Despite forty years of research on the potential role of chromium in carbohydrate and lipid metabolism, significant progress has only recently been made regarding the mode of action of chromium at a molecular level. The oligopeptide low-molecular-weight chromium-binding substance (LMWCr) may function as part of a nove...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2000.tb01841.x
更新日期:2000-03-01 00:00:00
abstract::Two recent studies suggest that when consuming a low-calcium diet, low efficiency of calcium absorption (measured as fractional calcium absorption) is a problem in the elderly; this is also an important risk factor for hip fracture. These studies show that elderly women are less able to compensate for low calcium inta...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb06959.x
更新日期:2001-10-01 00:00:00
abstract::Studies of the effects of oral contraceptives and other drugs on folic acid absorption are reviewed. In 1 study, estradiol, progesterone, and estrone did not inhibit folate conjugase nor interfere with the passage of folate conjugase across the lysosomal membrane. 12 women taking an oral contraceptive (norethisteron...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1974.tb06260.x
更新日期:1974-02-01 00:00:00
abstract::Intestinal adaptation, in terms of increasing intestinal length and weight, usually occurs rapidly after small-bowel resection. However, this response depends on provision of enteral nutrients. If total parenteral nutrition without enteral feeding is prolonged, hypoplasia of the intestinal mucosa results. Adaptation i...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1989.tb02837.x
更新日期:1989-07-01 00:00:00
abstract::Prospective studies suggest that dietary vitamin D may at least modestly reduce the risk of breast cancer. This review addresses issues raised by recent studies, including differences in findings related to dietary source of vitamin D, menopausal status, and tumor characteristics. It also discusses the optimal timing ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00271.x
更新日期:2007-10-01 00:00:00
abstract::The identity of the protein responsible for hemochromatosis, the iron overload disease, has eluded scientists for years. However, a recent report identifies the gene where the hemochromatosis defect lies. It is a gene that encodes a major histocompatibility complex (MHC) class-1-like protein called HLA-H. The mechanis...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1996.tb03949.x
更新日期:1996-09-01 00:00:00
abstract::Inflammation is a strong risk factor for cardiovascular disease. Dietary plant sterols are known to reduce plasma cholesterol levels and thereby reduce cardiovascular risk. Recent observations from animal and human studies have demonstrated anti-inflammatory effects of phytosterols. For example, several animal and hum...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2011.00399.x
更新日期:2011-07-01 00:00:00
abstract::As compared with three meals per day, a nibbling diet led to decreases in serum levels of total cholesterol and insulin. ...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1990.tb02961.x
更新日期:1990-07-01 00:00:00
abstract::The role of maternal vitamin A supplements in decreasing the risk of mother-to-child HIV transmission has been examined in sub-Saharan Africa. Overall, there is no reduction in either mortality or HIV transmission in two recent studies. Contrary to expectations, one study reported an increased risk of transmission usi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2003.aug.280-284
更新日期:2003-08-01 00:00:00
abstract::Meta-analyses on 6 of 12 studies of the effect of improvement of the vitamin A status of deficient children living in poverty and social and biological deprivation conclude that mortality reduction can be expected. The demonstrated effects on incidence, prevalence and severity of specific morbidities under these condi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1994.tb01407.x
更新日期:1994-04-01 00:00:00
abstract::The European Union is implementing a new regulatory framework for nutrition and health claims (HCs) that will greatly impact the communication of health messages on foodstuffs. In particular, approved HCs will be included in a positive register of generic claims. In the currently available literature, assessment of th...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00322.x
更新日期:2010-10-01 00:00:00
abstract::Milk represents a unique resource for translational medicine: It contains a rich pool of biologically active molecules with demonstrated clinical benefits. The ongoing characterization of the mechanistic process through which milk components promote development and immunity has revealed numerous milk-derived compounds...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuv009
更新日期:2015-07-01 00:00:00
abstract::Recently published literature has been reviewed to determine whether lycopene, beta-carotene, alpha-carotene, and beta-cryptoxanthin are associated with reductions in cancer risk and whether study findings differ by study design. A total of 57 publications meeting pre-defined inclusion and exclusion criteria were iden...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2009.00225.x
更新日期:2009-09-01 00:00:00
abstract::This case report describes a 14-month-old Guatemalan boy suffering from diarrhea and malnutrition. He had been healthy and experienced normal growth until weaning, which began at six months of age. Introduction of semisolid foods at this time was accompanied by bouts of diarrhea and a reduced growth rate. After admiss...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1990.tb02937.x
更新日期:1990-05-01 00:00:00
abstract::Copper transport at the cellular level is achieved by a coordinate series of interactions between passive and active membrane transport proteins, vesicles, and soluble peptides. Knowing the function of each component of this complex network has made the task of delineating the mechanism of intracellular copper homeost...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb07017.x
更新日期:2001-09-01 00:00:00
abstract::Worldwide, the number of individuals who are co-infected with human immunodeficiency virus (HIV) and tuberculosis is increasing greatly. The "triple trouble" of HIV and tuberculosis infection and malnutrition may put those infected at greater risk than those with any of the three conditions alone. Further investigatio...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2003.marr.81-90
更新日期:2003-03-01 00:00:00
abstract::It has been nearly 15 years since the first review on pregnancy and iron deficiency was published in Nutrition Reviews. Many unresolved issues raised in that seminal review have been addressed. New proteins involved in nonheme and heme iron transport have been identified in the enterocyte, and information on the roles...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2012.00550.x
更新日期:2013-01-01 00:00:00
abstract:CONTEXT:The association between dairy product intake and the risk of developing type 2 diabetes (T2D) or cardiovascular disease (CVD) has been investigated in several studies, but little attention was given to the role of sex as a moderator of these associations. (In this article, the term "sex" is used to denote the b...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuz006
更新日期:2019-06-01 00:00:00
abstract::Dietary reference intakes (DRIs) for vitamin C for healthy U.S. populations are currently being formulated by the Panel on Dietary Antioxidants and Related Compounds of the Food and Nutrition Board of the Institute of Medicine. A major task of the Panel is to analyze the evidence of adverse effects of high-dose vitami...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1999.tb06926.x
更新日期:1999-03-01 00:00:00
abstract::A food intake pattern specifying amounts and types of food was created for Canada's revised food guide, Eating Well with Canada's Food Guide (2007), using a two-step modeling process. In step one, food composites were manipulated to develop a food intake pattern. The second step used the step one food intake pattern t...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00295.x
更新日期:2007-04-01 00:00:00
abstract:INTRODUCTION:The omega-3 long-chain polyunsaturated fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are important for brain development and cognitive performance. Because they are semi-essential fatty acids, they must be obtained from food. However, the dietary reference intakes of DHA and EPA ha...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuaa060
更新日期:2020-09-11 00:00:00
abstract::The role of polyphenols in human nutrition is discussed on the basis of their redox chemistry, which accounts for the observed antioxidant effect and in turn for their protective effect against atherosclerosis. Epidemiologic data, together with experimental pathology and cell biology, support the recommendation that o...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1999.tb06951.x
更新日期:1999-08-01 00:00:00
abstract::The popularity of energy drinks has increased rapidly in the past decade. One of the main reasons people use energy drinks is to counteract effects of insufficient sleep or sleepiness. Risks associated with energy drink use, including those related to sleep loss, may be disproportionately borne by racial minorities an...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/nure.12137
更新日期:2014-10-01 00:00:00
abstract:CONTEXT:Fish oil and omega-3 polyunsaturated fatty acids (ω-3 PUFAs) have anti-inflammatory properties, but their effect on psoriasis and its comorbidities remains inconclusive. OBJECTIVE:The aim of this quantitative systematic review was to evaluate the efficacy and safety of fish oil and its components in the treatm...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuz098
更新日期:2020-10-01 00:00:00