Abstract:
:Despite forty years of research on the potential role of chromium in carbohydrate and lipid metabolism, significant progress has only recently been made regarding the mode of action of chromium at a molecular level. The oligopeptide low-molecular-weight chromium-binding substance (LMWCr) may function as part of a novel insulin-signaling autoamplification mechanism. The proposed mechanism of action also sheds some light on the potential of chromium-containing compounds as nutritional supplements or in the treatment of adult-onset diabetes and other conditions. The potential relationship between the results of recent studies on diabetic patients and the proposed mode of action of LMWCr are discussed.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Vincent JBdoi
10.1111/j.1753-4887.2000.tb01841.xkeywords:
subject
Has Abstractpub_date
2000-03-01 00:00:00pages
67-72issue
3 Pt 1eissn
0029-6643issn
1753-4887journal_volume
58pub_type
杂志文章,评审abstract::A relationship between folate and neuropsychiatric disorders has been inferred from clinical observation and from the enhanced understanding of the role of folate in critical brain metabolic pathways. Depressive symptoms are the most common neuropsychiatric manifestation of folate deficiency. Conversely, borderline lo...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1997.tb06468.x
更新日期:1997-05-01 00:00:00
abstract::Functional genomics, commonly applied to the genes and enzymes involved in metabolism of chemicals, can also be applied to enzymes involved in the metabolism of nutrients. Although in its infancy, genomics can be used to determine relationships between nutrition and toxicology, drug metabolism, and cancer. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb05510.x
更新日期:2001-08-01 00:00:00
abstract::Perchlorate inhibits the uptake of iodide into the thyroid gland, thereby possibly affecting the synthesis of thyroid hormones. Pregnant women and their fetuses and newborns have the greatest potential for risk of adverse health effects following exposure to perchlorate. Perchlorate is present in some foods and in dri...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2009.00260.x
更新日期:2010-01-01 00:00:00
abstract:CONTEXT:Contrary to nutritional guidelines, accumulating evidence shows that pregnant women's energy intakes remain stable throughout trimesters. Although pregnant women may eat below their needs or underreport their energy intakes, it is also relevant to question how energy requirements - estimated through measurement...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuaa093
更新日期:2020-09-25 00:00:00
abstract::From late 1991 to mid-1993, cases of optic neuropathy of unknown etiology, which first appeared in unusual numbers in a western province of Cuba, spread and multiplied throughout the island. The dominant symptoms changed, becoming increasingly those of peripheral neuropathy. Incidence rates peaked in April 1993. An es...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1993.tb03766.x
更新日期:1993-12-01 00:00:00
abstract::The primary factor determining selenium concentration in human milk is the maternal selenium intake. A significant correlation between selenium in human milk and maternal selenium intake has been reviewed in papers from different regions of the world. Infants fed human milk have higher selenium intake than those fed c...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1995.tb01543.x
更新日期:1995-06-01 00:00:00
abstract:CONTEXT:The use of the internet and technology as a medium for delivering online nutrition education (ONE) has increased; however, evidence-based studies exploring factors that contribute to best practices in online interventions have not emerged. OBJECTIVE:The purpose of this systematic review was to identify factors...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuz032
更新日期:2019-10-01 00:00:00
abstract::Genistein is a soy-derived biologically active isoflavone that exhibits diverse health-promoting effects. An increasing body of evidence shows that genistein influences lipid homeostasis and insulin resistance, counteracts inflammatory cytokines, and possesses antidiabetic properties. Genistein also impedes cancer pro...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/nure.12044
更新日期:2013-08-01 00:00:00
abstract::Fish and shellfish are widely available foods that provide important nutrients, particularly n-3 polyunsaturated fatty acids (n-3 PUFAs), to many populations globally. These nutrients, especially docosahexaenoic acid, confer benefits to brain and visual system development in infants and reduce risks of certain forms o...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2011.00415.x
更新日期:2011-09-01 00:00:00
abstract::Proanthocyanidins are a major group of flavonoids in the human diet, known for their strong antioxidant properties. Emerging evidence from clinical studies indicates a role of proanthocyanidins in modulating glucose homeostasis, and higher proanthocyanidin intake has been associated with reduced risk of diabetes. On t...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nux028
更新日期:2017-08-01 00:00:00
abstract::Data from epidemiologic, experimental, and animal studies indicate that diet plays an important role in the etiology of gastric cancer. High intake of fresh fruits and vegetables, lycopene and lycopene-containing food products, and potentially vitamin C and selenium may reduce the risk for gastric cancer. Data also su...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2008.00029.x
更新日期:2008-05-01 00:00:00
abstract::Sarcopenia is the degenerative loss of skeletal muscle that occurs naturally in individuals as they age. Although many factors underlie sarcopenia, epidemiological and experimental evidence suggests that low-grade chronic inflammation is an important contributor to its progression. Still, few healthcare professionals ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00364.x
更新日期:2007-12-01 00:00:00
abstract::Undernutrition is a major contributor to child mortality and total global disease burden. Ready-to-use therapeutic food (RUTF) is recommended by the World Health Organization for community-based management of uncomplicated forms of severe acute malnutrition. New research has evaluated the role of RUTF for the preventi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00302.x
更新日期:2010-07-01 00:00:00
abstract::Studies of the effects of oral contraceptives and other drugs on folic acid absorption are reviewed. In 1 study, estradiol, progesterone, and estrone did not inhibit folate conjugase nor interfere with the passage of folate conjugase across the lysosomal membrane. 12 women taking an oral contraceptive (norethisteron...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1974.tb06260.x
更新日期:1974-02-01 00:00:00
abstract::In a recent case-control study of 164 patients with clinically diagnosed Alzheimer's disease (AD), including 76 patients with the AD diagnosis confirmed postmortem, mean total serum homocysteine concentration was found to be significantly higher than that of a control group of elderly individuals with no evidence of c...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1999.tb06936.x
更新日期:1999-04-01 00:00:00
abstract::Glucokinase plays a major role in the control of hepatic glucose uptake and storage as glycogen. Small amounts of fructose-1-phosphate, in the presence of relatively high glucose levels, markedly stimulate glucokinase through a novel mechanism of regulation involving dissociation from a regulatory protein and transloc...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/002966402320289377
更新日期:2002-08-01 00:00:00
abstract::Intrinsic aging of the brain and its relationship to age-related neurodegenerative diseases need to be understood as part of global aging, which results from gradual accumulation of a variety of kinds of cellular and molecular damage. While certain kinds of molecular lesions are particularly associated with specific d...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00343.x
更新日期:2010-12-01 00:00:00
abstract::Dietary management has been considered an alternative means of modulating adiponectin levels. The purpose of this review is to examine the scientific evidence regarding the effect of diet on adiponectin levels in blood. Clinical trials were selected from Medline until April 2010 using the following MeSH terms: adipoki...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2011.00414.x
更新日期:2011-10-01 00:00:00
abstract::The optimal timing of umbilical cord clamping has been debated in the scientific literature for at least the last century, when cord clamping practices shifted from delayed towards immediate clamping. Recent research provides evidence for the beneficial effect of delayed cord clamping on infant iron status. The presen...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2011.00430.x
更新日期:2011-11-01 00:00:00
abstract::The regulatory properties of a principal glutamine transport system of skeletal muscle may control the balance between muscle protein synthesis and breakdown. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1989.tb02843.x
更新日期:1989-07-01 00:00:00
abstract::Insulin resistance is the core metabolic abnormality in type 2 diabetes. Its high prevalence and its association with dyslipidemia, hypertension, hyperinsulinemia, and high coronary and cerebrovascular mortality put it in the forefront as the plausible target for aggressive intervention. Measurements of insulin sensit...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2003.dec.397-412
更新日期:2003-12-01 00:00:00
abstract::The burden of maternal morbidity and mortality in developing countries is high. Each year, 600,000 women die from pregnancy-related causes and 62 million women suffer from morbidity and complications of pregnancy. The extent to which maternal nutrition can improve maternal health and survival is not well understood. E...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/00296640260130759
更新日期:2002-05-01 00:00:00
abstract::It has become increasingly evident in recent years that the gut microbiome and the brain communicate in a bidirectional manner, with each possibly affecting the other's functions. Substantial research has aimed to understand the mechanisms of this interaction and to outline strategies for preventing or treating nervou...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuy009
更新日期:2018-07-01 00:00:00
abstract::Dietary fat intake and its effect on human health is a hotly debated issue and major point of interest in nutrition research and practice today. This review traces the history of dietary fat intake, the influence of human evolution on dietary fat intake, and the relationship between dietary fat and health. ...
journal_title:Nutrition reviews
pub_type: 历史文章,杂志文章
doi:10.1111/j.1753-4887.1999.tb01770.x
更新日期:1999-01-01 00:00:00
abstract::Some specific hungers for vitamins or minerals can be explained as learned preferences, facilitated by the novel diet preferences shown by rats deficient in specific nutrients. Specific hunger for sodium, however, is a result of an innate, unlearned behavior pattern. ...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1968.tb00820.x
更新日期:1968-01-01 00:00:00
abstract::Manganese is an essential nutrient that also may be toxic at high concentrations. Subjects chronically exposed to manganese-laden dust in industrial settings develop neuropsychological changes that resemble Parkinson's disease. Manganese has been proposed as an additive to gasoline (as a replacement for the catalytic ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2004.tb00037.x
更新日期:2004-04-01 00:00:00
abstract::Working Group 2 of the Healthy Diet Research Committee of International Life Sciences Institute Japan (WG2) assessed the concept and practice of healthy eating in the ready-to-eat food/meal industry in Japan. WG2 interviewed 14 arbitrarily selected member companies that included "health" or "nutrition" in their manage...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuaa089
更新日期:2020-12-01 00:00:00
abstract::Vascular defects associated with dietary copper deficiency may result from altered interactions between vascular smooth muscle cells and nitric oxide. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1993.tb03101.x
更新日期:1993-06-01 00:00:00
abstract:CONTEXT:The presence of retail food establishments around schools can be a potentiating or protective factor for overweight in students, depending on access to these places as well as types of foods available therein. The hypothesis for this study was that a greater density and proximity of retail food establishments a...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuz110
更新日期:2020-10-01 00:00:00
abstract::Anthocyanins are a group of bioactive compounds present in plant foods. Although they have consistently shown an anti-inflammatory effect both in vitro and in vivo, their mechanisms of action are not fully understood and have only recently begun to be elucidated. The aim of this review is to highlight the anti-inflamm...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuu066
更新日期:2015-06-01 00:00:00