Abstract:
:Manganese is an essential nutrient that also may be toxic at high concentrations. Subjects chronically exposed to manganese-laden dust in industrial settings develop neuropsychological changes that resemble Parkinson's disease. Manganese has been proposed as an additive to gasoline (as a replacement for the catalytic properties of lead), which has generated increased research interest in the possible deleterious effects of environmental exposure to manganese. Low-level exposure to manganese has been implicated in neurologic changes, decreased learning ability in school-aged children, and increased propensity for violence in adults. However, a thorough review of the literature shows very weak cause-and-effect relationships that do not justify concern about environmental exposure to manganese for most of the North American population.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Finley JWdoi
10.1111/j.1753-4887.2004.tb00037.xkeywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
148-53issue
4eissn
0029-6643issn
1753-4887journal_volume
62pub_type
杂志文章,评审abstract:Context:Type 2 diabetes (T2D) is a major health problem worldwide that is associated with increased morbidity and mortality. There is increased interest in the value of different nutrition-based strategies for preventing the development of T2D. Objective:This review aims to cover current knowledge regarding the effect...
journal_title:Nutrition reviews
pub_type: 杂志文章,meta分析
doi:10.1093/nutrit/nuy014
更新日期:2018-06-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is an age-dependent degeneration of motor neurons in the central nervous system. ALS is not caused by faulty nutrition. Recent data suggest that ALS could be an oxidative neurotoxicity induced by a mutation in the SOD1 protein. This finding extends beyond the simple loss of an antio...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01698.x
更新日期:1998-03-01 00:00:00
abstract::Two recent studies suggest that when consuming a low-calcium diet, low efficiency of calcium absorption (measured as fractional calcium absorption) is a problem in the elderly; this is also an important risk factor for hip fracture. These studies show that elderly women are less able to compensate for low calcium inta...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb06959.x
更新日期:2001-10-01 00:00:00
abstract::Intrinsic aging of the brain and its relationship to age-related neurodegenerative diseases need to be understood as part of global aging, which results from gradual accumulation of a variety of kinds of cellular and molecular damage. While certain kinds of molecular lesions are particularly associated with specific d...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00343.x
更新日期:2010-12-01 00:00:00
abstract::A ventilator-dependent, extremely obese adolescent patient with Prader-Willi syndrome was nutritionally managed using a parenteral, protein-sparing modified fast. A solution containing only amino acids, electrolytes, vitamins, and macro- and micro-minerals helped create a ketotic state and facilitate weaning from the ...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1991.tb03035.x
更新日期:1991-08-01 00:00:00
abstract::This case report describes a 14-month-old Guatemalan boy suffering from diarrhea and malnutrition. He had been healthy and experienced normal growth until weaning, which began at six months of age. Introduction of semisolid foods at this time was accompanied by bouts of diarrhea and a reduced growth rate. After admiss...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1990.tb02937.x
更新日期:1990-05-01 00:00:00
abstract::Two recent studies on the effects of single high-fat meals on endothelial function have postulated an additional mechanism by which dietary lipids can impact atherosclerosis. These studies found that dietary lipids decrease the ability of blood vessels to dilate and that this modification of endothelial function was p...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb06135.x
更新日期:1998-06-01 00:00:00
abstract::Continually expanding evidence has moved inexorably toward establishing key functions for cellular retinol-binding protein (CRBP) in retinoid metabolism. These experimental data integrate into a model of CRBP as a chaperone that protects retinol from the cellular milieu and interacts with certain retinoid-metabolizing...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2000.tb01870.x
更新日期:2000-08-01 00:00:00
abstract::Low-density lipoprotein cholesterol (LDL-C) plays a causal role in atherosclerosis. One way to reduce LDL-C levels is to inhibit cholesterol absorption. Plant sterols and stanols compete with cholesterol for absorption in the intestine and induce an average decrease in LDL-C by 5% to 15% in a dose-dependent manner, bu...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuw059
更新日期:2017-02-01 00:00:00
abstract::A large number of biologically active components have been found in human milk (HM), and in both human and animal models, studies have provided some evidence suggesting that HM composition can be altered by maternal exposures, subsequently influencing health outcomes for the breastfed child. Evidence varies from the r...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuz019
更新日期:2019-05-21 00:00:00
abstract::Gluten-related disorders (GRDs) are gradually emerging as epidemiologically relevant diseases, with a global prevalence estimated to be approximately 5% in the population. Conditions related to gluten ingestion include celiac disease (CD), wheat allergy (WA), and nonceliac gluten sensitivity (NCGS). Although mediated ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nux068
更新日期:2018-02-01 00:00:00
abstract::Health claims for foods are permitted in an increasing number of countries, but there are very few studies evaluating their effect on purchase behavior and consumer health. There are significant differences between countries but, in general, consumers see health claims as useful; they prefer short, succinct wording ra...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2005.tb00382.x
更新日期:2005-07-01 00:00:00
abstract::A new study of the possible advantages of each of the eight dipeptides for intravenous nutrition focuses on kinetics of tyrosine and glutamine injected intravenously. Tyrosine and glutamine are two of the three amino acids that are difficult to use directly in the preparation of nutrient solutions due to low solubilit...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1995.tb01529.x
更新日期:1995-04-01 00:00:00
abstract::Isoflavones present in soy may have risk and benefits to human health. Human gut microflora have been shown to exert metabolic activities on isoflavones, which influences bioavailability and bioactivity. Absorption of isoflavones is likely to occur in the small intestine where there is a diverse range of microfloral s...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2003.jun.204-213
更新日期:2003-06-01 00:00:00
abstract::Mitochondria exert crucial physiological functions that create complex links among nutrition, health, and disease. While mitochondrial dysfunction with subsequent impairment of oxidative phosphorylation (OXPHOS) is the hallmark of the rare inherited OXPHOS diseases, OXPHOS dysfunction also plays a central role in the ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00363.x
更新日期:2011-02-01 00:00:00
abstract::Functional genomics, commonly applied to the genes and enzymes involved in metabolism of chemicals, can also be applied to enzymes involved in the metabolism of nutrients. Although in its infancy, genomics can be used to determine relationships between nutrition and toxicology, drug metabolism, and cancer. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb05510.x
更新日期:2001-08-01 00:00:00
abstract::Probiotics and prebiotics have long been appreciated for their positive influences on gut health. Research on the mechanisms and effects of these agents shows that their impact reaches beyond the intestine. Effects on the microecology and pathology of the oral cavity, stomach, and vaginal tract have been observed. Lik...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00272.x
更新日期:2007-11-01 00:00:00
abstract::Studying the effects of dehydration on cognitive function presents a variety of unique and difficult challenges to investigators. These challenges, which are addressed in this article, can be divided into three general categories: 1) choosing an appropriate method of generating a consistent level of dehydration; 2) de...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2012.00524.x
更新日期:2012-11-01 00:00:00
abstract::Food fortification is an important strategy to combat iron and zinc deficiency. This review covers the basic concepts of food fortification, as well as its advantages and disadvantages. The main characteristics of the most common zinc and iron compounds used in this procedure are also analyzed. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/00296640260085958
更新日期:2002-02-01 00:00:00
abstract::Iron is essential for oxygen transport, oxidative metabolism, and cellular growth. Interactions between iron and other dietary factors play a significant role in determining the adequacy of iron nutrition and have important implications for food fortification in developing countries. Vitamin A and vitamin C deficiency...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1997.tb06461.x
更新日期:1997-04-01 00:00:00
abstract::A relationship between folate and neuropsychiatric disorders has been inferred from clinical observation and from the enhanced understanding of the role of folate in critical brain metabolic pathways. Depressive symptoms are the most common neuropsychiatric manifestation of folate deficiency. Conversely, borderline lo...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1997.tb06468.x
更新日期:1997-05-01 00:00:00
abstract::The development of our understanding of the function of vitamin D from its discovery in the second and third decades of the 20(th) century to its hormonal activation of its nuclear receptor and to its present position of an important factor in public health has been traced. The key discoveries of the conversion of vit...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2008.00105.x
更新日期:2008-10-01 00:00:00
abstract::Berries contain powerful antioxidants, potential allergens, and other bioactive compounds. Genetic and environmental factors affect production and storage of such compounds. For this reason breeding and biotechnological approaches are currently used to control or to increase the content of specific health-related comp...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2009.00178.x
更新日期:2009-05-01 00:00:00
abstract::The evidence for beneficial effects of exercise training in the prevention and management of insulin resistance is convincing, although the mechanism remains to be fully elucidated. The increase in insulin sensitivity after a bout of exercise appears to be enhanced after training, but disappears within days of inactiv...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-01 00:00:00
abstract::The popularity of energy drinks has increased rapidly in the past decade. One of the main reasons people use energy drinks is to counteract effects of insufficient sleep or sleepiness. Risks associated with energy drink use, including those related to sleep loss, may be disproportionately borne by racial minorities an...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/nure.12137
更新日期:2014-10-01 00:00:00
abstract::A recent randomized, double-blind, placebo-controlled trial found that protein supplementation improved recovery from femoral fractures in an elderly population. A 6-month course of protein supplementation (20 g/day, 5 days/week) improved serum prealbumin and insulin-like growth factor I (IGF-I) concentrations, minimi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01672.x
更新日期:1998-11-01 00:00:00
abstract::Optimal nutrition can improve well-being and might mitigate the risk and morbidity associated with coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This review summarizes nutritional guidelines to support dietary counseling provided by dietitians and heal...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuaa067
更新日期:2020-07-12 00:00:00
abstract::In response to recent studies from India suggesting that malnutrition, as assessed by anthropometric indexes, affects metabolism of oral progestogens, this study administered a mini-pill containing .35 mg of norethindrone (NET) and combination pills containing 250 or 150 mcg of d-norgestrel (d-NG) and either 50 or 30 ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1984.tb02317.x
更新日期:1984-05-01 00:00:00
abstract::Outbreaks of foodborne disease owing to contamination with Listeria monocytogenes bacteria have usually been associated with the development of severe invasive disease. A recent report has provided clear documentation showing that outbreaks of L. monocytogenes also present as gastroenteritis and fever. Further studies...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1997.tb01597.x
更新日期:1997-02-01 00:00:00
abstract::Recent data on the expression and function of the ZIP family of proteins has suggested that these zinc transporters may be useful biomarkers for the diagnosis and prognosis of human breast cancer. This exciting new area of research opens the door for the use of a variety of nutritionally regulated genes and proteins a...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2008.00020.x
更新日期:2008-03-01 00:00:00