The role of glutamine in intensive care unit patients: mechanisms of action and clinical outcome.

Abstract:

:Patients in the intensive care unit are at high risk of glutamine depletion and subsequent complications. Several controlled studies and a meta-analysis have concluded that glutamine supplementation has beneficial effects on the clinical outcome of critically ill and surgical patients. These results may be explained by glutamine's influences on the inflammatory response, oxidative stress, cell protection, and the gut barrier. In addition, glutamine may also improve glucose metabolism by reducing insulin resistance.

journal_name

Nutr Rev

journal_title

Nutrition reviews

authors

Coëffier M,Déchelotte P

doi

10.1111/j.1753-4887.2005.tb00123.x

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

65-9

issue

2

eissn

0029-6643

issn

1753-4887

journal_volume

63

pub_type

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