Using genetic admixture to study the biology of obesity traits and to map genes in admixed populations.


:Differences among ethnic and racial groups in obesity-related traits have been clearly established in the scientific literature. To explore the genetic component underlying these differences, the genetic admixture approach has been used. In this approach, ancestry informative genetic markers are used to estimate a quantitative value representing the degree of ancestral background in individuals of admixed genetic background. Genetic admixture has been successfully used to explain racial and ethnic variation in obesity related traits; however, the understanding and measure of cultural and environmental components that also influence these phenotypes still requires further exploration.


Nutr Rev


Nutrition reviews


Fernández JR,Shiver MD





Has Abstract


2004-07-01 00:00:00




7 Pt 2








  • Ready-to-use therapeutic food for prevention of childhood undernutrition.

    abstract::Undernutrition is a major contributor to child mortality and total global disease burden. Ready-to-use therapeutic food (RUTF) is recommended by the World Health Organization for community-based management of uncomplicated forms of severe acute malnutrition. New research has evaluated the role of RUTF for the preventi...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Hendricks KM

    更新日期:2010-07-01 00:00:00

  • Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption.

    abstract::Fish and shellfish are widely available foods that provide important nutrients, particularly n-3 polyunsaturated fatty acids (n-3 PUFAs), to many populations globally. These nutrients, especially docosahexaenoic acid, confer benefits to brain and visual system development in infants and reduce risks of certain forms o...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Mahaffey KR,Sunderland EM,Chan HM,Choi AL,Grandjean P,Mariën K,Oken E,Sakamoto M,Schoeny R,Weihe P,Yan CH,Yasutake A

    更新日期:2011-09-01 00:00:00

  • Role of medicinal plants, herbs, and spices in protecting human health.

    abstract::The body of knowledge about plants, herbs, and spices and their respective and collective roles in promoting human health is modest. Flavonoids in tea and anthocyanins in tart cherries were presented as examples of how to move forward in understanding active compounds. Dietary compounds, their roles in maintaining hum...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Balentine DA,Albano MC,Nair MG

    更新日期:1999-09-01 00:00:00

  • Maximizing peak bone mass: calcium supplementation increases bone mineral density in children.

    abstract::Attaining peak skeletal bone mass during childhood may reduce the incidence of osteoporosis in later life. A recent study in six- to 14-year-old identical twins showed that calcium supplementation increased bone mineral density. The effects of supplementation were especially pronounced in prepubertal children. ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章



    更新日期:1992-11-01 00:00:00

  • Cholesterol: where science and public health policy intersect.

    abstract::Current US guidelines for cholesterol recommend limiting intake of cholesterol to <300 mg/day for the general population and <200 mg/day for individuals with elevated low-density lipoprotein cholesterol. These recommendations, however, are at odds with international (e.g., Canada, United Kingdom, and Australia) guidel...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Brownawell AM,Falk MC

    更新日期:2010-06-01 00:00:00

  • Lactose intolerance and irritable bowel syndrome.

    abstract::A recent study on lactose intolerance and irritable bowel syndrome has shown that subjective lactose intolerance is increased in patients with irritable bowel syndrome, despite no increase in the prevalence of lactose maldigestion. ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Mascolo R,Saltzman JR

    更新日期:1998-10-01 00:00:00

  • Current status and issues concerning Health Japan 21 (second term).

    abstract::The national health promotion program, Health Japan 21 (second term), began in 2013. This program has set 5 basic goals: to extend healthy life expectancy and reduce health disparity, to prevent noncommunicable disease, to improve function for social life, to establish a social environment for health, and to improve l...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: Tsuji I

    更新日期:2020-12-01 00:00:00

  • Recommendations for optimization of fortified and blended food aid products from the United States.

    abstract::Fortified blended foods (FBFs) were introduced into the Food for Peace program (also known as US Public Law 480) in the 1960s. Minimal changes have since been made to their formulations. A Food Aid Quality Enhancement Project to assess the nutritional adequacy of FBFs for vulnerable populations was conducted, and the ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Fleige LE,Moore WR,Garlick PJ,Murphy SP,Turner EH,Dunn ML,van Lengerich B,Orthoefer FT,Schaefer SE

    更新日期:2010-05-01 00:00:00

  • Interindividual variability in the cholesterol-lowering effect of supplementation with plant sterols or stanols.

    abstract::Low-density lipoprotein cholesterol (LDL-C) plays a causal role in atherosclerosis. One way to reduce LDL-C levels is to inhibit cholesterol absorption. Plant sterols and stanols compete with cholesterol for absorption in the intestine and induce an average decrease in LDL-C by 5% to 15% in a dose-dependent manner, bu...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Fumeron F,Bard JM,Lecerf JM

    更新日期:2017-02-01 00:00:00

  • Underexploited African grain crops: a nutritional resource.

    abstract::The African grain deficit is projected to surpass its current production of 50 x 10(6) metric tons/year by the turn of the century. The biodiversity of the African continent, on which there are more native cereals than on any other continent, can serve to reduce the vulnerability of the continent's populations at seri...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Fahey JW

    更新日期:1998-09-01 00:00:00

  • Retinoids and carotenoids as inhibitors of carcinogenesis and inducers of cell-cell communication.

    abstract::In cell cultures of carcinogen-initiated fibroblasts, a number of retinoids and carotenoids can reversibly inhibit progression to the transformed state. The anticarcinogenic action of retinoids and carotenoids is closely correlated with enhanced gap-junction cell-to-cell communication and with increased synthesis of t...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Wolf G

    更新日期:1992-09-01 00:00:00

  • Supplemental calcium and risk reduction of hypertension, pregnancy-induced hypertension, and preeclampsia: an evidence-based review by the US Food and Drug Administration.

    abstract::The labeling of health claims that meet the significant scientific agreement (SSA) standard (authorized health claims) and qualified health claims on conventional foods and dietary supplements requires premarket approval by the US Food and Drug Administration (FDA). FDA conducts an evidence-based review to determine w...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Trumbo PR,Ellwood KC

    更新日期:2007-02-01 00:00:00

  • Evolution of our understanding of vitamin D.

    abstract::The development of our understanding of the function of vitamin D from its discovery in the second and third decades of the 20(th) century to its hormonal activation of its nuclear receptor and to its present position of an important factor in public health has been traced. The key discoveries of the conversion of vit...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: DeLuca HF

    更新日期:2008-10-01 00:00:00

  • Timing of umbilical cord clamping: effect on iron endowment of the newborn and later iron status.

    abstract::The optimal timing of umbilical cord clamping has been debated in the scientific literature for at least the last century, when cord clamping practices shifted from delayed towards immediate clamping. Recent research provides evidence for the beneficial effect of delayed cord clamping on infant iron status. The presen...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Chaparro CM

    更新日期:2011-11-01 00:00:00

  • Nutrition and depression: the role of folate.

    abstract::A relationship between folate and neuropsychiatric disorders has been inferred from clinical observation and from the enhanced understanding of the role of folate in critical brain metabolic pathways. Depressive symptoms are the most common neuropsychiatric manifestation of folate deficiency. Conversely, borderline lo...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Alpert JE,Fava M

    更新日期:1997-05-01 00:00:00

  • Food poisoning, listeriosis, and febrile gastroenteritis.

    abstract::Outbreaks of foodborne disease owing to contamination with Listeria monocytogenes bacteria have usually been associated with the development of severe invasive disease. A recent report has provided clear documentation showing that outbreaks of L. monocytogenes also present as gastroenteritis and fever. Further studies...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审



    更新日期:1997-02-01 00:00:00

  • Pharmacological effects and clinical applications of propionyl-L-carnitine.

    abstract::Propionyl-L-carnitine (PLC) is a naturally occurring derivative of carnitine that plays an important role in the metabolism of both carbohydrates and lipids, leading to an increase of ATP generation. PLC, however, is not only a metabolic drug; it is also a potent antiradical agent and thus may protect tissues from oxi...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Mingorance C,Rodriguez-Rodriguez R,Justo ML,Herrera MD,de Sotomayor MA

    更新日期:2011-05-01 00:00:00

  • Fruits and vegetables and the risk of stroke.

    abstract::Combining data from two large-scale prospective observational studies in women and men, investigators link the consumption of fruits and vegetables to the risk of ischemic stroke. Of interest is their breakdown of these foods into cruciferous vegetables and citrus fruit juice, which confer the greatest protection. ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Feldman EB

    更新日期:2001-01-01 00:00:00

  • Beyond cholesterol-lowering effects of plant sterols: clinical and experimental evidence of anti-inflammatory properties.

    abstract::Inflammation is a strong risk factor for cardiovascular disease. Dietary plant sterols are known to reduce plasma cholesterol levels and thereby reduce cardiovascular risk. Recent observations from animal and human studies have demonstrated anti-inflammatory effects of phytosterols. For example, several animal and hum...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Othman RA,Moghadasian MH

    更新日期:2011-07-01 00:00:00

  • Phenolics: prooxidants or antioxidants?

    abstract::Both essential and nonessential dietary antioxidants have been suggested to be beneficial for health. However, studies show that many antioxidants can also exhibit prooxidant behavior under certain conditions. The antioxidant/prooxidant activity of phenolics is dependent on such factors as metal-reducing potential, ch...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Decker EA

    更新日期:1997-11-01 00:00:00

  • Bone quality and vitamin K2 in type 2 diabetes: review of preclinical and clinical studies.

    abstract::Type 2 diabetic patients are at high risk of bone fractures even if their bone mineral density is normal or high. This is likely explained by poor bone quality and extraskeletal factors. The present review was conducted to provide an overview of the currently available preclinical and clinical evidence on the effect o...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Iwamoto J,Sato Y,Takeda T,Matsumoto H

    更新日期:2011-03-01 00:00:00

  • Optimization of nutrition: polyphenols and vascular protection.

    abstract::The role of polyphenols in human nutrition is discussed on the basis of their redox chemistry, which accounts for the observed antioxidant effect and in turn for their protective effect against atherosclerosis. Epidemiologic data, together with experimental pathology and cell biology, support the recommendation that o...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Ursini F,Tubaro F,Rong J,Sevanian A

    更新日期:1999-08-01 00:00:00

  • Relationship between the gut microbiome and brain function.

    abstract::It has become increasingly evident in recent years that the gut microbiome and the brain communicate in a bidirectional manner, with each possibly affecting the other's functions. Substantial research has aimed to understand the mechanisms of this interaction and to outline strategies for preventing or treating nervou...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Mohajeri MH,La Fata G,Steinert RE,Weber P

    更新日期:2018-07-01 00:00:00

  • Retail food environment around schools and overweight: a systematic review.

    abstract:CONTEXT:The presence of retail food establishments around schools can be a potentiating or protective factor for overweight in students, depending on access to these places as well as types of foods available therein. The hypothesis for this study was that a greater density and proximity of retail food establishments a...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: da Costa Peres CM,Gardone DS,Costa BVL,Duarte CK,Pessoa MC,Mendes LL

    更新日期:2020-10-01 00:00:00

  • Formation and human risk of carcinogenic heterocyclic amines formed from natural precursors in meat.

    abstract::A group of heterocyclic amines that are mutagens and rodent carcinogens form when meat is cooked to medium and well-done states. The precursors of these compounds are natural meat components: creatinine, amino acids, and sugars. Defined model systems of dry-heated precursors mimic the amounts and proportions of hetero...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Knize MG,Felton JS

    更新日期:2005-05-01 00:00:00

  • Influence of observational study design on the interpretation of cancer risk reduction by carotenoids.

    abstract::Recently published literature has been reviewed to determine whether lycopene, beta-carotene, alpha-carotene, and beta-cryptoxanthin are associated with reductions in cancer risk and whether study findings differ by study design. A total of 57 publications meeting pre-defined inclusion and exclusion criteria were iden...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Musa-Veloso K,Card JW,Wong AW,Cooper DA

    更新日期:2009-09-01 00:00:00

  • Small amounts of dietary fructose dramatically increase hepatic glucose uptake through a novel mechanism of glucokinase activation.

    abstract::Glucokinase plays a major role in the control of hepatic glucose uptake and storage as glycogen. Small amounts of fructose-1-phosphate, in the presence of relatively high glucose levels, markedly stimulate glucokinase through a novel mechanism of regulation involving dissociation from a regulatory protein and transloc...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Watford M

    更新日期:2002-08-01 00:00:00

  • Self-regulation and the response to concerns about food and beverage marketing to children in the United States.

    abstract::The Institute of Medicine reported in 2005 that food and beverage marketing to children and youth is "out of balance with healthful diets". The dominant policy response in the United States has been to encourage self-regulation by the food, beverage, advertising, and media industries. From a nutrition perspective, thi...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Wilde P

    更新日期:2009-03-01 00:00:00

  • Discontinuation of total parenteral nutrition in a patient with acquired immunodeficiency syndrome: a Canadian perspective.

    abstract::Provision of nourishment to terminally ill patients has been a controversial topic in clinical medicine. Determination of the limits of palliative care requires an understanding of the disease process, as well as the boundaries of patient self-determination. With the advent of living wills, the determination of the pa...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: Knowles JB,Gilmore N

    更新日期:1994-08-01 00:00:00

  • Maternal nutrition, health, and survival.

    abstract::The burden of maternal morbidity and mortality in developing countries is high. Each year, 600,000 women die from pregnancy-related causes and 62 million women suffer from morbidity and complications of pregnancy. The extent to which maternal nutrition can improve maternal health and survival is not well understood. E...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Christian P

    更新日期:2002-05-01 00:00:00