Visceral adipocytes and the metabolic syndrome.

Abstract:

:Recently, the high responsiveness of omental adipocytes to positive lipolytic stimuli has been clearly demonstrated in women. We conclude that adipose tissue fatty acid release, storage capacity, and secreted cytokines may all be involved in the etiology of the metabolic syndrome. The anatomical location of visceral adipocytes close to the liver, combined with possible depot-specific alterations in various adipocyte or adipose tissue features likely play critical roles in this process. This highly complex etiology is concordant with the heterogeneous clinical manifestations of the metabolic syndrome, and suggests possible interindividual variability in the extent to which each pathophysiological mechanism is involved.

journal_name

Nutr Rev

journal_title

Nutrition reviews

authors

Tchernof A

doi

10.1111/j.1753-4887.2007.tb00324.x

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

S24-9

issue

6 Pt 2

eissn

0029-6643

issn

1753-4887

journal_volume

65

pub_type

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