Abstract：
:Adequate folate status in early pregnancy is critical to prevent congenital malformations, yet little is known about whether exposure to folate, specifically folic acid supplementation beyond the recommended dose, influences chronic health outcomes. The link between maternal folate levels and risk of childhood asthma and allergic disease has been investigated in 10 large prospective cohort studies that reported conflicting results. While the majority of studies reported no association, those supporting a positive relationship found a small increase in risk that was generally transient in nature, confined to early childhood, and associated with folic acid supplementation in late pregnancy. This systematic review presents background information on maternal folate exposure and childhood asthma, synthesizes the current epidemiologic evidence in the context of the methodological differences among studies and their potential limitations, and offers direction for future research.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Brown SB,Reeves KW,Bertone-Johnson ERdoi
10.1111/nure.12080subject
Has Abstractpub_date
2014-01-01 00:00:00pages
55-64issue
1eissn
0029-6643issn
1753-4887journal_volume
72pub_type
杂志文章,评审abstract：Context:The metabolism of thyroid hormones, which are essential for normal development, involves many proteins and enzymes. It requires iodine as a key component but is also influenced by several other micronutrients, including selenium, zinc, iron, and vitamin A. Objective:This systematic review was designed to inves...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1093/nutrit/nuy008
更新日期：2018-06-01 00:00:00
abstract：:The impact of the obesity epidemic on women of childbearing age has been of particular concern in recent years as a result of studies linking maternal weight status to long-term adverse outcomes for obese mothers and their offspring. The US Institute of Medicine developed new gestational weight gain guidelines based o...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/nure.12074
更新日期：2013-10-01 00:00:00
abstract：:The human body is an ecosystem harboring complex site-specific microbial communities. The majority of these human-associated microbes are found in the intestinal tract, where they play important roles in energy uptake, vitamin synthesis, and epithelial and immunity development. Recent molecular studies have characteri...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2009.00237.x
更新日期：2009-11-01 00:00:00
abstract：:From late 1991 to mid-1993, cases of optic neuropathy of unknown etiology, which first appeared in unusual numbers in a western province of Cuba, spread and multiplied throughout the island. The dominant symptoms changed, becoming increasingly those of peripheral neuropathy. Incidence rates peaked in April 1993. An es...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1993.tb03766.x
更新日期：1993-12-01 00:00:00
abstract：:Studying the effects of dehydration on cognitive function presents a variety of unique and difficult challenges to investigators. These challenges, which are addressed in this article, can be divided into three general categories: 1) choosing an appropriate method of generating a consistent level of dehydration; 2) de...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2012.00524.x
更新日期：2012-11-01 00:00:00
abstract：:Studies of germ-free and conventional mice revealed that the intestinal bacterial population of the latter contributed to the provision of calories to the host by hydrolysis of indigestible plant polysaccharides to absorbable monosaccharides. The gut microbiota at the same time caused the suppression of a circulating ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2006.tb00173.x
更新日期：2006-01-01 00:00:00
abstract：:This review shows how some transcription factors respond to alterations in macronutrients. Carbohydrates induce enzymes for their metabolism and fatty acid synthesis. Fatty acids reduce carbohydrate processing, induce enzymes for their metabolism, and increase both gluconeogenesis and storage of fat. Fat stores help c...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2008.00039.x
更新日期：2008-06-01 00:00:00
abstract：:Choline is involved in methyl group metabolism and lipid transport and is a component of a number of important biological compounds including the membrane phospholipids lecithin, sphingomyelin, and plasmalogen; the neurotransmitter acetylcholine; and platelet activating factor. Although a required nutrient for several...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1994.tb01357.x
更新日期：1994-10-01 00:00:00
abstract：:Under conditions of energy balance, energy intake (EI) equals energy expenditure (EE), and the validity of EI may be determined by comparing these two measures. The doubly labeled water (DLW) method is the gold standard for the determination of EE. Its use in developed countries has showed an intense underreporting of...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/nr.2006.jul.319-330
更新日期：2006-07-01 00:00:00
abstract：:Malnourished children experience more severe measles infections at a greater frequency than well nourished children. In Africa, the mortality rate for measles infection is 25-50% in infants and young children with edematous malnutrition. There is some evidence that the altered immune responses of malnourished people...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1982.tb05310.x
更新日期：1982-07-01 00:00:00
abstract：:This report is the first in a series of publications resulting from the comprehensive effort being undertaken by the Food and Nutrition Board's Committee on the Scientific Evaluation of Dietary Reference Intakes and its panels and subcommittees. The history and rationale behind the development of the Dietary Reference...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1997.tb01623.x
更新日期：1997-09-01 00:00:00
abstract：:Observational studies document a positive relationship between vitamin D from the environment (sunlight or diet), circulating vitamin D status, and improved symptoms or prevention of multiple sclerosis (MS). Experimental animal models of MS reproduce the beneficial effects of vitamin D and 1,25(OH)(2)D(3). The geograp...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2008.00097.x
更新日期：2008-10-01 00:00:00
abstract：:Probiotics and prebiotics have long been appreciated for their positive influences on gut health. Research on the mechanisms and effects of these agents shows that their impact reaches beyond the intestine. Effects on the microecology and pathology of the oral cavity, stomach, and vaginal tract have been observed. Lik...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2007.tb00272.x
更新日期：2007-11-01 00:00:00
abstract：:The glucocorticoid dexamethasone (dex) stimulates differentiation of cultured preadipocytes of the 3T3-L1 cell line to adipocytes. The preadipocytes express a gene termed preadipocyte factor 1 (pref-1). The pref-1 gene product is abundant in preadipocytes but completely absent in adipocytes. Constitutive expression of...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1999.tb06907.x
更新日期：1999-10-01 00:00:00
abstract：CONTEXT:Serotonergic dysfunction, including reduced central serotonin levels, is associated with different psychiatric syndromes, including depression. As a serotonin precursor, 5-hydroxytryptophan has long been used as a nonpharmacological treatment for depression. OBJECTIVE:A systematic review and meta-analysis was ...
journal_title：Nutrition reviews
pub_type： 杂志文章,meta分析
doi：10.1093/nutrit/nuz039
更新日期：2020-01-01 00:00:00
abstract：:Urinary excretion of 3-methyl histidine was found to be reduced in starvation. Data show that the rate of muscle catabolism is reduced to a greater extent than muscle mass. Reutilization of amino acids appears not to be greatly enhanced during starvation. ...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1111/j.1753-4887.1974.tb00962.x
更新日期：1974-07-01 00:00:00
abstract：:The increasing need for nutrition professionals is driven by growing public interest in nutrition and the potential of nutrition to prevent and treat a variety of diet-related conditions. Health promotion units and health services face great challenges in trying to address current and future population health issues. ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2010.00315.x
更新日期：2010-09-01 00:00:00
abstract：:Gluten-related disorders (GRDs) are gradually emerging as epidemiologically relevant diseases, with a global prevalence estimated to be approximately 5% in the population. Conditions related to gluten ingestion include celiac disease (CD), wheat allergy (WA), and nonceliac gluten sensitivity (NCGS). Although mediated ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1093/nutrit/nux068
更新日期：2018-02-01 00:00:00
abstract：:The identity of the protein responsible for hemochromatosis, the iron overload disease, has eluded scientists for years. However, a recent report identifies the gene where the hemochromatosis defect lies. It is a gene that encodes a major histocompatibility complex (MHC) class-1-like protein called HLA-H. The mechanis...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1996.tb03949.x
更新日期：1996-09-01 00:00:00
abstract：:A recent study indicates that lowering homocysteine with folic acid and vitamin B6 significantly reduces the incidence of abnormal exercise electrocardiography tests and thus decreases the risk of atherosclerotic disease. Questions about study design and sample size, however, suggest that this conclusion may be premat...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2001.tb07016.x
更新日期：2001-07-01 00:00:00
abstract：:Dietary fat intake and its effect on human health is a hotly debated issue and major point of interest in nutrition research and practice today. This review traces the history of dietary fat intake, the influence of human evolution on dietary fat intake, and the relationship between dietary fat and health. ...
journal_title：Nutrition reviews
pub_type： 历史文章,杂志文章
doi：10.1111/j.1753-4887.1999.tb01770.x
更新日期：1999-01-01 00:00:00
abstract：:The dietary reference intakes (DRIs) are a set of reference intake levels for nutrients that can be used for planning diets and assessing nutrient inadequacies of individuals and groups. Since the publication of the DRI reports 1997-2004, the reference intake levels have been used for various purposes. While DRIs have...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/nure.12067
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:The primary aim of the current study was to synthesize evidence of the effect of social media use compared with no social media use as part of interventions to reduce risk factors for noncommunicable diseases. DATA SOURCES:Databases were searched up to June 10, 2014, using medical subject headings. A seconda...
journal_title：Nutrition reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1093/nutrit/nuv106
更新日期：2016-04-01 00:00:00
abstract：:This paper examines the speed of change in diet, activity, and obesity in the developing world, and notes potential exacerbating biological relationships that contribute to differences in the rates of change. The focus is on lower- and middle-income countries of Asia, Africa, the Middle East, and Latin America. These ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2004.tb00084.x
更新日期：2004-07-01 00:00:00
abstract：:The Second International Conference on Nutrition, organized by the Food and Agriculture Organization of the United Nations and the World Health Organization, will take place in November 2014. In 1992, the First International Conference on Nutrition declared, "Hunger and malnutrition are unacceptable." Twenty-two years...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/nure.12134
更新日期：2014-09-01 00:00:00
abstract：:The regulatory properties of a principal glutamine transport system of skeletal muscle may control the balance between muscle protein synthesis and breakdown. ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1989.tb02843.x
更新日期：1989-07-01 00:00:00
abstract：:Proanthocyanidins are a major group of flavonoids in the human diet, known for their strong antioxidant properties. Emerging evidence from clinical studies indicates a role of proanthocyanidins in modulating glucose homeostasis, and higher proanthocyanidin intake has been associated with reduced risk of diabetes. On t...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1093/nutrit/nux028
更新日期：2017-08-01 00:00:00
abstract：:Iodine intake influences the health of Americans today, but in different ways than it has in the past. In the early 1900s, iodine deficiency was responsible for widespread endemic goiter in the United States. The incidence of goiter was markedly reduced by the introduction of iodine supplementation of salt and other f...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1999.tb06940.x
更新日期：1999-06-01 00:00:00
abstract：:Green tea, rich in antioxidant and anti-inflammatory catechins, especially epigallocatechin gallate (EGCG), has been shown to reduce surrogate markers of atherosclerosis and lipid peroxidation, particularly LDL oxidation and malondialdehyde concentrations, in several in vitro, animal, and limited clinical studies. Epi...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/nr.2007.aug.361-375
更新日期：2007-08-01 00:00:00
abstract：CONTEXT:The use of the internet and technology as a medium for delivering online nutrition education (ONE) has increased; however, evidence-based studies exploring factors that contribute to best practices in online interventions have not emerged. OBJECTIVE:The purpose of this systematic review was to identify factors...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1093/nutrit/nuz032
更新日期：2019-10-01 00:00:00
