Abstract:
:This review shows how some transcription factors respond to alterations in macronutrients. Carbohydrates induce enzymes for their metabolism and fatty acid synthesis. Fatty acids reduce carbohydrate processing, induce enzymes for their metabolism, and increase both gluconeogenesis and storage of fat. Fat stores help control carbohydrate uptake by other cells. The following main transcription factors are discussed: carbohydrate response element-binding protein; sterol regulatory element-binding protein-1c, cyclic AMP response element-binding protein, peroxisome proliferator-activated receptor-alpha, and peroxisome proliferator-activated receptor-gamma.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Wise Adoi
10.1111/j.1753-4887.2008.00039.xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
321-5issue
6eissn
0029-6643issn
1753-4887pii
NURE039journal_volume
66pub_type
杂志文章,评审abstract::Lipid oxidation products are present in unknown amounts in the food supply of industrialized societies. Evidence for a putative role of some of these compounds in accelerating events in the atherogenic process--the initiation of endothelial injury, the accumulation of plaque, and the termination phase of thrombosis--c...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1993.tb03064.x
更新日期:1993-02-01 00:00:00
abstract::Both essential and nonessential dietary antioxidants have been suggested to be beneficial for health. However, studies show that many antioxidants can also exhibit prooxidant behavior under certain conditions. The antioxidant/prooxidant activity of phenolics is dependent on such factors as metal-reducing potential, ch...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1997.tb01580.x
更新日期:1997-11-01 00:00:00
abstract::Studies of germ-free and conventional mice revealed that the intestinal bacterial population of the latter contributed to the provision of calories to the host by hydrolysis of indigestible plant polysaccharides to absorbable monosaccharides. The gut microbiota at the same time caused the suppression of a circulating ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2006.tb00173.x
更新日期:2006-01-01 00:00:00
abstract::The glucocorticoid dexamethasone (dex) stimulates differentiation of cultured preadipocytes of the 3T3-L1 cell line to adipocytes. The preadipocytes express a gene termed preadipocyte factor 1 (pref-1). The pref-1 gene product is abundant in preadipocytes but completely absent in adipocytes. Constitutive expression of...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1999.tb06907.x
更新日期:1999-10-01 00:00:00
abstract::Green tea, rich in antioxidant and anti-inflammatory catechins, especially epigallocatechin gallate (EGCG), has been shown to reduce surrogate markers of atherosclerosis and lipid peroxidation, particularly LDL oxidation and malondialdehyde concentrations, in several in vitro, animal, and limited clinical studies. Epi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2007.aug.361-375
更新日期:2007-08-01 00:00:00
abstract:CONTEXT:The impact of various dietary interventions on rheumatoid arthritis (RA), characterized by immune-inflammatory response, has been subject to increased attention. OBJECTIVE:A systematic review was conducted to update the current knowledge on the effects of nutritional, dietary supplement, and fasting interventi...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuaa033
更新日期:2020-06-25 00:00:00
abstract::We present a case of an African-American child with vitamin D-deficient rickets. In addition to being solely breast-fed for the period of 1 year, he resided in New England, where exposure to ultraviolet light is limited owing to its northern latitude and long cold winters. He presented with classical signs of nutritio...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.2000.tb01867.x
更新日期:2000-07-01 00:00:00
abstract:Context:Obesity, type 2 diabetes, and dental caries are all major public health problems in the United Kingdom and contribute substantially to healthcare costs. Objective:A systematic review and meta-analysis was conducted to determine the effect of product reformulation measures on sugar intake and health outcomes. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,meta分析
doi:10.1093/nutrit/nuy015
更新日期:2019-03-01 00:00:00
abstract::The essential fatty acids (EFAs), particularly the n-3 long-chain polyunsaturated fatty acids (LCPs), are important for brain development during both the fetal and postnatal period. They are also increasingly seen to be of value in limiting the cognitive decline during aging. EFA deficiency was first shown over 75 yea...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2006.may.s24-s33
更新日期:2006-05-01 00:00:00
abstract::Maternal vitamin B6 status correlates birth weight with infant behavior and maternal infant interactions. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1991.tb07375.x
更新日期:1991-10-01 00:00:00
abstract::Intrinsic aging of the brain and its relationship to age-related neurodegenerative diseases need to be understood as part of global aging, which results from gradual accumulation of a variety of kinds of cellular and molecular damage. While certain kinds of molecular lesions are particularly associated with specific d...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00343.x
更新日期:2010-12-01 00:00:00
abstract::Type 2 diabetic patients are at high risk of bone fractures even if their bone mineral density is normal or high. This is likely explained by poor bone quality and extraskeletal factors. The present review was conducted to provide an overview of the currently available preclinical and clinical evidence on the effect o...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2011.00380.x
更新日期:2011-03-01 00:00:00
abstract::Adequate folate status in early pregnancy is critical to prevent congenital malformations, yet little is known about whether exposure to folate, specifically folic acid supplementation beyond the recommended dose, influences chronic health outcomes. The link between maternal folate levels and risk of childhood asthma ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/nure.12080
更新日期:2014-01-01 00:00:00
abstract::Current US guidelines for cholesterol recommend limiting intake of cholesterol to <300 mg/day for the general population and <200 mg/day for individuals with elevated low-density lipoprotein cholesterol. These recommendations, however, are at odds with international (e.g., Canada, United Kingdom, and Australia) guidel...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2010.00294.x
更新日期:2010-06-01 00:00:00
abstract::The daily subcutaneous injection of 0.3 U/kg of recombinant growth hormone (GH) for the two years prior to puberty in ten constitutionally growth-retarded children with normal pituitary function resulted in an average height gain of 10 cm per year. No manifestations of GH excess were seen, and a transient alteration i...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1992.tb01326.x
更新日期:1992-07-01 00:00:00
abstract::This case report describes a 14-month-old Guatemalan boy suffering from diarrhea and malnutrition. He had been healthy and experienced normal growth until weaning, which began at six months of age. Introduction of semisolid foods at this time was accompanied by bouts of diarrhea and a reduced growth rate. After admiss...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1990.tb02937.x
更新日期:1990-05-01 00:00:00
abstract::The present systematic review was performed to assess differences in the worldwide consumption of functional foods. The Medline and Scopus databases were used to search the existing literature. A total of 23 studies that examined functional food consumption and included information on the country, gender, and age of p...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2012.00492.x
更新日期:2012-08-01 00:00:00
abstract::Data from epidemiologic, experimental, and animal studies indicate that diet plays an important role in the etiology of gastric cancer. High intake of fresh fruits and vegetables, lycopene and lycopene-containing food products, and potentially vitamin C and selenium may reduce the risk for gastric cancer. Data also su...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2008.00029.x
更新日期:2008-05-01 00:00:00
abstract::Risks for gastric cancer in relation to diet and other environmental factors are receiving renewed attention. New developments include the emerging relationship between Helicobacter pylori infection and an increased risk for gastric cancer, and positive results of chemoprevention trials in decreasing gastric cancer ri...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1994.tb01394.x
更新日期:1994-03-01 00:00:00
abstract::Insulin resistance is the core metabolic abnormality in type 2 diabetes. Its high prevalence and its association with dyslipidemia, hypertension, hyperinsulinemia, and high coronary and cerebrovascular mortality put it in the forefront as the plausible target for aggressive intervention. Measurements of insulin sensit...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2003.dec.397-412
更新日期:2003-12-01 00:00:00
abstract::Two recent studies examined the association between chronic use of warfarin, a vitamin K antagonist, and fracture rate among older women. Whereas one study reported no association, the other reported a significantly higher risk for vertebral and rib fractures among warfarin users compared with nonusers. The effect of ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2000.tb01820.x
更新日期:2000-01-01 00:00:00
abstract::On April 7-8, 2014, the European Hydration Institute hosted a small group of experts at Castle Combe Manor House, United Kingdom, to discuss a range of issues related to human hydration, health, and performance. The meeting included 18 recognized experts who brought a wealth of experience and knowledge to the topics u...
journal_title:Nutrition reviews
pub_type:
doi:10.1093/nutrit/nuv056
更新日期:2015-09-01 00:00:00
abstract::Reported here is a summary of the proceedings of the Symposium on Plant Polyphenols: Nutrition, Health and Innovations, which was cosponsored by the Southeast Asia Region branch of the International Life Sciences Institute and the Nutrition Society of Malaysia in Kuala Lumpur, Malaysia, June 22-23, 2009. The symposium...
journal_title:Nutrition reviews
pub_type:
doi:10.1111/j.1753-4887.2010.00283.x
更新日期:2010-04-01 00:00:00
abstract::Malnourished children experience more severe measles infections at a greater frequency than well nourished children. In Africa, the mortality rate for measles infection is 25-50% in infants and young children with edematous malnutrition. There is some evidence that the altered immune responses of malnourished people...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1982.tb05310.x
更新日期:1982-07-01 00:00:00
abstract::Low-density lipoprotein cholesterol (LDL-C) plays a causal role in atherosclerosis. One way to reduce LDL-C levels is to inhibit cholesterol absorption. Plant sterols and stanols compete with cholesterol for absorption in the intestine and induce an average decrease in LDL-C by 5% to 15% in a dose-dependent manner, bu...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuw059
更新日期:2017-02-01 00:00:00
abstract::Lipases are key enzymes in the hydrolysis of triglycerides, phospholipids, and cholesteryl esters, including those of dietary origin. Their actions are essential to maintain lipid homeostasis and cardiovascular health. This report describes the finding and characterization of a new lipase of endothelial origin, one th...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1999.tb01814.x
更新日期:1999-09-01 00:00:00
abstract::Observational studies document a positive relationship between vitamin D from the environment (sunlight or diet), circulating vitamin D status, and improved symptoms or prevention of multiple sclerosis (MS). Experimental animal models of MS reproduce the beneficial effects of vitamin D and 1,25(OH)(2)D(3). The geograp...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2008.00097.x
更新日期:2008-10-01 00:00:00
abstract::Thermal injury in animal models clearly alters glucose metabolism. Insulin resistance results, with the wound in the skin receiving increased glucose, presumably to be used for wound healing and fighting invasion by foreign organisms. Using the whole-body imaging capacities of PET, it may now be possible to explore in...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01636.x
更新日期:1998-01-01 00:00:00
abstract::This review critically summarizes the literature on neighborhood determinants of obesity and proposes a conceptual framework to guide future inquiry. Thirty-seven studies met all inclusion criteria and revealed that the influence of neighborhood-level factors appears mixed. Neighborhood-level measures of economic reso...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.00001.x
更新日期:2008-01-01 00:00:00
abstract::The African grain deficit is projected to surpass its current production of 50 x 10(6) metric tons/year by the turn of the century. The biodiversity of the African continent, on which there are more native cereals than on any other continent, can serve to reduce the vulnerability of the continent's populations at seri...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01767.x
更新日期:1998-09-01 00:00:00