Abstract：
:Malnourished children experience more severe measles infections at a greater frequency than well nourished children. In Africa, the mortality rate for measles infection is 25-50% in infants and young children with edematous malnutrition. There is some evidence that the altered immune responses of malnourished people permit widespread viral infection. A recent study by Whittle et al investigated the immune response of malnourished children to measles in order to define the cellular basis of severe viral infection in nutritional deficiency. Peripheral blood mononuclear cells obtained from well-nourished and malnourished Nigerian children were compared. Significantly more virus was found in the cultures of cells from malnourished children as opposed to well-nourished controls, with a negative correlation between virus yield and log serum albumin level. The production of interferon from the mononuclear cells of the 2 groups did not differ significantly, leaving unexplained the increased yield of virus by cells of malnourished children. The more extensive viral invasion of tissues and widespread inflammation and cell death in malnourished children infected with measles may contribute to the generation of more complexes and consequent immunosuppression, in turn resulting in secondary infections.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
doi
10.1111/j.1753-4887.1982.tb05310.xsubject
Has Abstractpub_date
1982-07-01 00:00:00pages
203-5issue
7eissn
0029-6643issn
1753-4887journal_volume
40pub_type
杂志文章,评审abstract：:Studying the effects of dehydration on cognitive function presents a variety of unique and difficult challenges to investigators. These challenges, which are addressed in this article, can be divided into three general categories: 1) choosing an appropriate method of generating a consistent level of dehydration; 2) de...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2012.00524.x
更新日期：2012-11-01 00:00:00
abstract：:Provision of nourishment to terminally ill patients has been a controversial topic in clinical medicine. Determination of the limits of palliative care requires an understanding of the disease process, as well as the boundaries of patient self-determination. With the advent of living wills, the determination of the pa...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:This report is the first in a series of publications resulting from the comprehensive effort being undertaken by the Food and Nutrition Board's Committee on the Scientific Evaluation of Dietary Reference Intakes and its panels and subcommittees. The history and rationale behind the development of the Dietary Reference...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1997.tb01623.x
更新日期：1997-09-01 00:00:00
abstract：:Dietary reference intakes (DRIs) for vitamin C for healthy U.S. populations are currently being formulated by the Panel on Dietary Antioxidants and Related Compounds of the Food and Nutrition Board of the Institute of Medicine. A major task of the Panel is to analyze the evidence of adverse effects of high-dose vitami...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1999.tb06926.x
更新日期：1999-03-01 00:00:00
abstract：:This review shows how some transcription factors respond to alterations in macronutrients. Carbohydrates induce enzymes for their metabolism and fatty acid synthesis. Fatty acids reduce carbohydrate processing, induce enzymes for their metabolism, and increase both gluconeogenesis and storage of fat. Fat stores help c...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2008.00039.x
更新日期：2008-06-01 00:00:00
abstract：:This article reviews the environmental impact of genetically modified crops through discussion of environmental risk assessment and includes several case studies. Influence of European regulatory and political issues is considered. ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/nr.2003.jun.S105-S109
更新日期：2003-06-01 00:00:00
abstract：:The demand for dairy products is growing rapidly, especially in emerging markets. Dairy products are nutrient rich and, therefore, an important food group for ensuring nutrient security in the future. In many countries, dairy contributes significantly to nutrient intake. Meta-analyses have shown that consumption of da...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1093/nutrit/nuv040
更新日期：2015-08-01 00:00:00
abstract：:Aging is associated with a chronic low-grade inflammatory status that contributes to chronic diseases such as age-related muscle wasting, kidney disease, and diabetes mellitus. Since advanced glycation end products (AGEs) are known to be proinflammatory, this systematic review examined the relation between the dietary...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/nure.12141
更新日期：2014-10-01 00:00:00
abstract：:The development of our understanding of the function of vitamin D from its discovery in the second and third decades of the 20(th) century to its hormonal activation of its nuclear receptor and to its present position of an important factor in public health has been traced. The key discoveries of the conversion of vit...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2008.00105.x
更新日期：2008-10-01 00:00:00
abstract：:On April 7-8, 2014, the European Hydration Institute hosted a small group of experts at Castle Combe Manor House, United Kingdom, to discuss a range of issues related to human hydration, health, and performance. The meeting included 18 recognized experts who brought a wealth of experience and knowledge to the topics u...
journal_title：Nutrition reviews
pub_type：
doi：10.1093/nutrit/nuv056
更新日期：2015-09-01 00:00:00
abstract：:Chylomicrons have a suppressive effect on food consumption, which is attributed to apolipoprotein A-IV (apo A-IV). This protein is found in cerebrospinal fluid in vivo, and its infusion into the third ventricle of the brain reduces food intake. These findings suggest that this apolipoprotein operates through the centr...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1993.tb03120.x
更新日期：1993-09-01 00:00:00
abstract：:Type 2 diabetic patients are at high risk of bone fractures even if their bone mineral density is normal or high. This is likely explained by poor bone quality and extraskeletal factors. The present review was conducted to provide an overview of the currently available preclinical and clinical evidence on the effect o...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2011.00380.x
更新日期：2011-03-01 00:00:00
abstract：:Choline is involved in methyl group metabolism and lipid transport and is a component of a number of important biological compounds including the membrane phospholipids lecithin, sphingomyelin, and plasmalogen; the neurotransmitter acetylcholine; and platelet activating factor. Although a required nutrient for several...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1994.tb01357.x
更新日期：1994-10-01 00:00:00
abstract：:Obesity is an established risk factor for postmenopausal, but not premenopausal, development of breast cancer. Evidence for a positive association between obesity and breast cancer mortality is mounting. Avoiding adult weight gain and maintaining a healthy body weight may contribute importantly to decreasing breast ca...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/nr.2003.febr.73-76
更新日期：2003-02-01 00:00:00
abstract：:Rather than being an inevitable consequence of age, cognitive decline can occur with marked variation among individuals. In this context, nutrition is one factor that is believed to be influential. When considering the potential role of diet, two factors need to be considered. First, cognitive or brain reserve is said...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2010.00324.x
更新日期：2010-11-01 00:00:00
abstract：:Isoflavones present in soy may have risk and benefits to human health. Human gut microflora have been shown to exert metabolic activities on isoflavones, which influences bioavailability and bioactivity. Absorption of isoflavones is likely to occur in the small intestine where there is a diverse range of microfloral s...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/nr.2003.jun.204-213
更新日期：2003-06-01 00:00:00
abstract：:Gluten-related disorders (GRDs) are gradually emerging as epidemiologically relevant diseases, with a global prevalence estimated to be approximately 5% in the population. Conditions related to gluten ingestion include celiac disease (CD), wheat allergy (WA), and nonceliac gluten sensitivity (NCGS). Although mediated ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1093/nutrit/nux068
更新日期：2018-02-01 00:00:00
abstract：:We present a case of the eosinophilia-myalgia syndrome in a patient taking large doses of L-tryptophan for sedation. He developed the now-classic findings of myalgias, skin changes, and marked eosinophilia. This syndrome was first recognized in late 1989, and epidemiologic studies have demonstrated an association of t...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1111/j.1753-4887.1990.tb02969.x
更新日期：1990-08-01 00:00:00
abstract：:Children one to ten years of age who had had the fetal alcohol syndrome were compared with age-matched children with intrauterine growth retardation without exposure to alcohol. Those with fetal alcohol syndrome had greater impairment of immune function. ...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1111/j.1753-4887.1982.tb05259.x
更新日期：1982-02-01 00:00:00
abstract：:Prebiotic and probiotic therapies are new strategies being used to treat gastrointestinal diseases. Recent evidence suggests that the administration of select prebiotics and probiotics, alone or in combination (the latter called "synbiotic" therapy) may improve the clinical outcome of patients with ulcerative colitis....
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2006.tb00196.x
更新日期：2006-03-01 00:00:00
abstract：:The popularity of energy drinks has increased rapidly in the past decade. One of the main reasons people use energy drinks is to counteract effects of insufficient sleep or sleepiness. Risks associated with energy drink use, including those related to sleep loss, may be disproportionately borne by racial minorities an...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/nure.12137
更新日期：2014-10-01 00:00:00
abstract：:Fortified blended foods (FBFs) were introduced into the Food for Peace program (also known as US Public Law 480) in the 1960s. Minimal changes have since been made to their formulations. A Food Aid Quality Enhancement Project to assess the nutritional adequacy of FBFs for vulnerable populations was conducted, and the ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2010.00288.x
更新日期：2010-05-01 00:00:00
abstract：:Advanced glycation end products (AGEs) formed via the Maillard reaction during the thermal processing of food contributes to the flavor, color, and aroma of food. A proportion of food-derived AGEs and their precursors is intestinally absorbed and accumulates within cells and tissues. AGEs have been implicated in the p...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1093/nutrit/nuv030
更新日期：2015-11-01 00:00:00
abstract：:Several studies have indicated that omega-3 poly-unsaturated fatty acids in fish oil have protective effects on cardiovascular disease by reducing vascular endothelial inflammation in atherosclerosis. In a recent study, supplementation of patients with fish oil following coronary angioplasty elevated levels of lipid p...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2000.tb07812.x
更新日期：2000-02-01 00:00:00
abstract：:Healthy humans regulate daily water balance remarkably well across their lifespan despite changes in biological development and exposure to stressors on hydration status. Acute or chronic body water deficits result when intakes are reduced or losses increase, but day-to-day hydration is generally well maintained so lo...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2005.tb00152.x
更新日期：2005-06-01 00:00:00
abstract：:A recent randomized, double-blind, placebo-controlled trial found that protein supplementation improved recovery from femoral fractures in an elderly population. A 6-month course of protein supplementation (20 g/day, 5 days/week) improved serum prealbumin and insulin-like growth factor I (IGF-I) concentrations, minimi...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1998.tb01672.x
更新日期：1998-11-01 00:00:00
abstract：:Current or recent low vitamin D status (or proxy measures such as dietary intake or ambient ultraviolet radiation) is linked to several chronic diseases, including osteoporosis, cancers, and cardiovascular and autoimmune diseases. Low prenatal vitamin D status may also increase susceptibility to such diseases in later...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2008.00126.x
更新日期：2008-12-01 00:00:00
abstract：:Although body weight is considered to positively affect bones of children and adults, recent studies suggest that overweight and obesity in childhood and adolescence reduce bone mineral content below what would be predicted based on weight and are associated with an increase in incidence of childhood fractures. ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/002966402760240327
更新日期：2002-01-01 00:00:00
abstract：:Current US guidelines for cholesterol recommend limiting intake of cholesterol to <300 mg/day for the general population and <200 mg/day for individuals with elevated low-density lipoprotein cholesterol. These recommendations, however, are at odds with international (e.g., Canada, United Kingdom, and Australia) guidel...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2010.00294.x
更新日期：2010-06-01 00:00:00
abstract：:Mammalian cells use an exquisitely sensitive mechanism to control the amount of cholesterol and fatty acids in their membranes. This process relies on a feedback system that adjusts the rates of transcription of genes encoding the low density lipoprotein receptor and multiple enzymes in the cholesterol and fatty acid ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1998.tb01680.x
更新日期：1998-02-01 00:00:00
