Abstract:
:The identity of the protein responsible for hemochromatosis, the iron overload disease, has eluded scientists for years. However, a recent report identifies the gene where the hemochromatosis defect lies. It is a gene that encodes a major histocompatibility complex (MHC) class-1-like protein called HLA-H. The mechanism by which an HLA-H defect alters iron metabolism is still unidentified. However, this new discovery will certainly ignite a new wave of study into the physiology of iron metabolism and its regulation.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Fleet JCdoi
10.1111/j.1753-4887.1996.tb03949.xsubject
Has Abstractpub_date
1996-09-01 00:00:00pages
285-7issue
9eissn
0029-6643issn
1753-4887journal_volume
54pub_type
杂志文章,评审abstract::Sarcopenia is the degenerative loss of skeletal muscle that occurs naturally in individuals as they age. Although many factors underlie sarcopenia, epidemiological and experimental evidence suggests that low-grade chronic inflammation is an important contributor to its progression. Still, few healthcare professionals ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00364.x
更新日期:2007-12-01 00:00:00
abstract::The African grain deficit is projected to surpass its current production of 50 x 10(6) metric tons/year by the turn of the century. The biodiversity of the African continent, on which there are more native cereals than on any other continent, can serve to reduce the vulnerability of the continent's populations at seri...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01767.x
更新日期:1998-09-01 00:00:00
abstract::In recent years it has been suggested that patients with celiac disease can be adequately followed up on the basis of merely clinical and serological response to a gluten-free diet. Thus, a duodenal biopsy some months after commencement of a gluten-free diet would no longer be necessary. We report here the case of a c...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2004.tb00062.x
更新日期:2004-09-01 00:00:00
abstract:Context:Type 2 diabetes (T2D) is a major health problem worldwide that is associated with increased morbidity and mortality. There is increased interest in the value of different nutrition-based strategies for preventing the development of T2D. Objective:This review aims to cover current knowledge regarding the effect...
journal_title:Nutrition reviews
pub_type: 杂志文章,meta分析
doi:10.1093/nutrit/nuy014
更新日期:2018-06-01 00:00:00
abstract::In order to examine the prevalence of overweight and obesity in childhood within the Indian subcontinent, a meta-analysis of studies was conducted. Within the data sets analyzed, six homogeneous statistical subgroups were observed and three levels of prevalence were discernible (low, intermediate, and high). The poole...
journal_title:Nutrition reviews
pub_type: 杂志文章,meta分析
doi:10.1111/nure.12130
更新日期:2014-08-01 00:00:00
abstract::Low-density lipoprotein cholesterol (LDL-C) plays a causal role in atherosclerosis. One way to reduce LDL-C levels is to inhibit cholesterol absorption. Plant sterols and stanols compete with cholesterol for absorption in the intestine and induce an average decrease in LDL-C by 5% to 15% in a dose-dependent manner, bu...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuw059
更新日期:2017-02-01 00:00:00
abstract::Magnesium deficiency is prevalent in women of childbearing age in both developing and developed countries. The need for magnesium increases during pregnancy, and the majority of pregnant women likely do not meet this increased need. Magnesium deficiency or insufficiency during pregnancy may pose a health risk for both...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuw018
更新日期:2016-09-01 00:00:00
abstract::Based on the fact that energy content in 1 gram of alcohol is 29 kJ or 7.1 kcal, alcohol consumption can lead to weight gain. The present review was conducted to analyze the effects of alcohol consumption on body weight. A search of the Medline database for the period 1984 to March 2010 was conducted to identify cross...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2011.00403.x
更新日期:2011-08-01 00:00:00
abstract::Overall, several investigations indicate that garlic and its organic allyl sulfur components inhibit the cancer process. Furthermore, these studies reveal that the benefits of garlic are not limited to a specific species, a particular tissue, or a specific carcinogen. Finally, odor is not a prerequisite for the protec...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1996.tb03823.x
更新日期:1996-11-01 00:00:00
abstract::Recent findings indicate that cocoa and chocolate, when processed appropriately, may contain relatively large amounts of flavonoids, particularly catechin and epicatechin. We review the benefits of these flavonoids, specifically with regard to cardiovascular health, and raise several unresolved issues that suggest the...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2005.dec.427-430
更新日期:2005-12-01 00:00:00
abstract::Genistein is a soy-derived biologically active isoflavone that exhibits diverse health-promoting effects. An increasing body of evidence shows that genistein influences lipid homeostasis and insulin resistance, counteracts inflammatory cytokines, and possesses antidiabetic properties. Genistein also impedes cancer pro...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/nure.12044
更新日期:2013-08-01 00:00:00
abstract::The burden of maternal morbidity and mortality in developing countries is high. Each year, 600,000 women die from pregnancy-related causes and 62 million women suffer from morbidity and complications of pregnancy. The extent to which maternal nutrition can improve maternal health and survival is not well understood. E...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/00296640260130759
更新日期:2002-05-01 00:00:00
abstract::Maternal vitamin B6 status correlates birth weight with infant behavior and maternal infant interactions. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1991.tb07375.x
更新日期:1991-10-01 00:00:00
abstract::The evidence for beneficial effects of exercise training in the prevention and management of insulin resistance is convincing, although the mechanism remains to be fully elucidated. The increase in insulin sensitivity after a bout of exercise appears to be enhanced after training, but disappears within days of inactiv...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-01 00:00:00
abstract::A 75-year-old patient with anuric renal failure developed a significant metabolic alkalosis thought to be due to the enteral absorption of "nonsystemic" antacid administered in large daily doses for prevention of recurrent peptic ulcer disease. ...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1990.tb02948.x
更新日期:1990-06-01 00:00:00
abstract::Plant-based diets, and more specifically plant-based proteins, have been the subject of growing interest from researchers and consumers because of their potential health benefits as well as their positive environmental impact. Of course, plant proteins are found in plant foods, and positive health benefits of plant fo...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuz028
更新日期:2019-11-01 00:00:00
abstract:Context:The metabolism of thyroid hormones, which are essential for normal development, involves many proteins and enzymes. It requires iodine as a key component but is also influenced by several other micronutrients, including selenium, zinc, iron, and vitamin A. Objective:This systematic review was designed to inves...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuy008
更新日期:2018-06-01 00:00:00
abstract::Green tea, rich in antioxidant and anti-inflammatory catechins, especially epigallocatechin gallate (EGCG), has been shown to reduce surrogate markers of atherosclerosis and lipid peroxidation, particularly LDL oxidation and malondialdehyde concentrations, in several in vitro, animal, and limited clinical studies. Epi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2007.aug.361-375
更新日期:2007-08-01 00:00:00
abstract:CONTEXT:The impact of various dietary interventions on rheumatoid arthritis (RA), characterized by immune-inflammatory response, has been subject to increased attention. OBJECTIVE:A systematic review was conducted to update the current knowledge on the effects of nutritional, dietary supplement, and fasting interventi...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuaa033
更新日期:2020-06-25 00:00:00
abstract::The complementary feeding period, when solids and liquids other than breast milk and formula are added to the infant diet, is an important development window shaping infant growth and weight gain, metabolic development, and lifelong eating practices. Yet, relatively little is known about how the timing and types of fo...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuz057
更新日期:2020-12-01 00:00:00
abstract::In this review, the influence of fat depots on insulin resistance and the main characteristics of metabolically obese normal-weight and metabolically healthy obese phenotypes are discussed. Medline/PubMed and Science Direct were searched for articles related to the terms metabolically healthy obesity, metabolically ob...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuu007
更新日期:2015-03-01 00:00:00
abstract::Advanced glycation end products (AGEs) formed via the Maillard reaction during the thermal processing of food contributes to the flavor, color, and aroma of food. A proportion of food-derived AGEs and their precursors is intestinally absorbed and accumulates within cells and tissues. AGEs have been implicated in the p...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuv030
更新日期:2015-11-01 00:00:00
abstract::Body adiposity is known to be carefully regulated and to remain relatively stable for long periods of time in most mammalian species. This review summarizes old and recent data implicating insulin and leptin as key circulating signals to the central nervous system, particularly the ventral hypothalamus, in communicati...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/002966402320634797
更新日期:2002-10-01 00:00:00
abstract::Introduction of chimeric transferrin-chloramphenicol acetyltransferase genes into transgenic mice provides a model by which modulation of the human transferrin gene may be studied in vivo. Iron injected into this mouse model decreases liver expression of the reporter enzyme in a manner analogous to its effect on plasm...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1991.tb03029.x
更新日期:1991-07-01 00:00:00
abstract::The daily subcutaneous injection of 0.3 U/kg of recombinant growth hormone (GH) for the two years prior to puberty in ten constitutionally growth-retarded children with normal pituitary function resulted in an average height gain of 10 cm per year. No manifestations of GH excess were seen, and a transient alteration i...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1992.tb01326.x
更新日期:1992-07-01 00:00:00
abstract::Health claims for foods are permitted in an increasing number of countries, but there are very few studies evaluating their effect on purchase behavior and consumer health. There are significant differences between countries but, in general, consumers see health claims as useful; they prefer short, succinct wording ra...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2005.tb00382.x
更新日期:2005-07-01 00:00:00
abstract::Two recent studies suggest that when consuming a low-calcium diet, low efficiency of calcium absorption (measured as fractional calcium absorption) is a problem in the elderly; this is also an important risk factor for hip fracture. These studies show that elderly women are less able to compensate for low calcium inta...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb06959.x
更新日期:2001-10-01 00:00:00
abstract::A recent study indicates that lowering homocysteine with folic acid and vitamin B6 significantly reduces the incidence of abnormal exercise electrocardiography tests and thus decreases the risk of atherosclerotic disease. Questions about study design and sample size, however, suggest that this conclusion may be premat...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb07016.x
更新日期:2001-07-01 00:00:00
abstract::The latter half of the 20th century has witnessed rapid advances in medicine. Concurrently, secular trends in lifestyle practices in our increasingly sedentary society have led to burgeoning rates of obesity, metabolic syndrome, and type 2 diabetes. The number of Americans with type 2 diabetes more than doubled betwee...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00354.x
更新日期:2007-12-01 00:00:00
abstract::Food fortification is an important strategy to combat iron and zinc deficiency. This review covers the basic concepts of food fortification, as well as its advantages and disadvantages. The main characteristics of the most common zinc and iron compounds used in this procedure are also analyzed. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/00296640260085958
更新日期:2002-02-01 00:00:00