Abstract:
:The Metabolic Syndrome, also known as Syndrome X, refers to a constellation of atherosclerotic risk factors, including insulin resistance, hyperinsulinemia, dyslipidemia, essential hypertension, and abdominal obesity. We review four major published studies involving animals and humans that may be linked together in a unified hypothesis and justify a comprehensive approach in the treatment of this ever-increasing syndrome.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Roth JL,Mobarhan S,Clohisy Mdoi
10.1301/002966402320583398keywords:
subject
Has Abstractpub_date
2002-10-01 00:00:00pages
335-7issue
10 Pt 1eissn
0029-6643issn
1753-4887journal_volume
60pub_type
杂志文章,评审abstract::Vitamin E per unit serum cholesterol has been found to correlate with memory performance in a recent analysis of data from the Third National Health and Nutrition Examination Survey. Because vitamin E is thought to be protective against vascular disease, this finding is consistent with the growing body of evidence tha...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2000.tb07540.x
更新日期:2000-04-01 00:00:00
abstract::Age-related macular degeneration (AMD) is a major cause of visual impairment in the United States. Currently there is no effective cure for this disease. Risk factors include decreased lutein and zeaxanthin status and obesity. Obesity is also an increasing public health concern. The alarming increase in the prevalence...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2005.tb00105.x
更新日期:2005-01-01 00:00:00
abstract::A meta-analysis of 13 case-control studies suggests that intakes of dietary fiber and risk of colon cancer are inversely associated. Weaker associations were observed between risk of colon cancer and dietary intake of ascorbic acid and beta-carotene. ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1993.tb03091.x
更新日期:1993-05-01 00:00:00
abstract::As compared with three meals per day, a nibbling diet led to decreases in serum levels of total cholesterol and insulin. ...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1990.tb02961.x
更新日期:1990-07-01 00:00:00
abstract::Two recent studies suggest that when consuming a low-calcium diet, low efficiency of calcium absorption (measured as fractional calcium absorption) is a problem in the elderly; this is also an important risk factor for hip fracture. These studies show that elderly women are less able to compensate for low calcium inta...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb06959.x
更新日期:2001-10-01 00:00:00
abstract::International nutrition will become increasingly concerned with evaluation of nutritional status at the community level to diagnose situations of risk for nutrient deficits and excesses, and to monitor the impact of remedial interventions. Advances in biologic concepts and technology (particularly miniaturization of a...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/00296640260130876
更新日期:2002-05-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is an age-dependent degeneration of motor neurons in the central nervous system. ALS is not caused by faulty nutrition. Recent data suggest that ALS could be an oxidative neurotoxicity induced by a mutation in the SOD1 protein. This finding extends beyond the simple loss of an antio...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01698.x
更新日期:1998-03-01 00:00:00
abstract::The popularity of energy drinks has increased rapidly in the past decade. One of the main reasons people use energy drinks is to counteract effects of insufficient sleep or sleepiness. Risks associated with energy drink use, including those related to sleep loss, may be disproportionately borne by racial minorities an...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/nure.12137
更新日期:2014-10-01 00:00:00
abstract::The essential fatty acids (EFAs), particularly the n-3 long-chain polyunsaturated fatty acids (LCPs), are important for brain development during both the fetal and postnatal period. They are also increasingly seen to be of value in limiting the cognitive decline during aging. EFA deficiency was first shown over 75 yea...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2006.may.s24-s33
更新日期:2006-05-01 00:00:00
abstract::Energy drinks are increasingly popular among athletes and others. Advertising for these products typically features images conjuring great muscle power and endurance; however, the scientific literature provides sparse evidence for an ergogenic role of energy drinks. Although the composition of energy drinks varies, mo...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/nure.12132
更新日期:2014-10-01 00:00:00
abstract::Attention to the different types of carbohydrates and their role in health and disease is relatively recent. FAO and WHO jointly published a report on carbohydrates in human nutrition in 1998, with a number of recommendations about increasing carbohydrate intake as a sound approach to the prevention of obesity. The gl...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1301/nr.2003.may.S34-S39
更新日期:2003-05-01 00:00:00
abstract::Continually expanding evidence has moved inexorably toward establishing key functions for cellular retinol-binding protein (CRBP) in retinoid metabolism. These experimental data integrate into a model of CRBP as a chaperone that protects retinol from the cellular milieu and interacts with certain retinoid-metabolizing...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2000.tb01870.x
更新日期:2000-08-01 00:00:00
abstract::The increasing prevalence of overweight and obesity highlight the need for improved intervention strategies to counteract this significant public health problem. To this end, it appears that increases in energy expenditure through exercise and other forms of physical activity may be an important component of effective...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2006.tb00235.x
更新日期:2006-02-01 00:00:00
abstract::Mitochondrial disorders (MDs) are caused by impairment of the mitochondrial electron transport chain (ETC). The ETC is needed for oxidative phosphorylation, which provides the cell with the most efficient energy outcome in terms of ATP production. One of the pathogenic mechanisms of MDs is the accumulation of reactive...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2009.00221.x
更新日期:2009-08-01 00:00:00
abstract::Two recent studies examined the association between chronic use of warfarin, a vitamin K antagonist, and fracture rate among older women. Whereas one study reported no association, the other reported a significantly higher risk for vertebral and rib fractures among warfarin users compared with nonusers. The effect of ...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2000.tb01820.x
更新日期:2000-01-01 00:00:00
abstract::Recently, the high responsiveness of omental adipocytes to positive lipolytic stimuli has been clearly demonstrated in women. We conclude that adipose tissue fatty acid release, storage capacity, and secreted cytokines may all be involved in the etiology of the metabolic syndrome. The anatomical location of visceral a...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00324.x
更新日期:2007-06-01 00:00:00
abstract::This review shows how some transcription factors respond to alterations in macronutrients. Carbohydrates induce enzymes for their metabolism and fatty acid synthesis. Fatty acids reduce carbohydrate processing, induce enzymes for their metabolism, and increase both gluconeogenesis and storage of fat. Fat stores help c...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2008.00039.x
更新日期:2008-06-01 00:00:00
abstract::Alcohol dehydrogenase (ADH) consists of a family of isozymes that convert alcohols to their corresponding aldehydes using NAD+ as a cofactor. The metabolism of ethanol by gastrointestinal ADH isozymes results in the production of acetaldehyde, a highly toxic compound that binds to cellular protein and DNA if not furth...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1998.tb01692.x
更新日期:1998-02-01 00:00:00
abstract::The evidence for beneficial effects of exercise training in the prevention and management of insulin resistance is convincing, although the mechanism remains to be fully elucidated. The increase in insulin sensitivity after a bout of exercise appears to be enhanced after training, but disappears within days of inactiv...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-01 00:00:00
abstract::The latter half of the 20th century has witnessed rapid advances in medicine. Concurrently, secular trends in lifestyle practices in our increasingly sedentary society have led to burgeoning rates of obesity, metabolic syndrome, and type 2 diabetes. The number of Americans with type 2 diabetes more than doubled betwee...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2007.tb00354.x
更新日期:2007-12-01 00:00:00
abstract::The development of our understanding of the function of vitamin D from its discovery in the second and third decades of the 20(th) century to its hormonal activation of its nuclear receptor and to its present position of an important factor in public health has been traced. The key discoveries of the conversion of vit...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2008.00105.x
更新日期:2008-10-01 00:00:00
abstract::There has been significant public debate about the susceptibility of research to biases of various kinds. The dialogue has extended to the peer-reviewed literature, scientific conferences, the mass media, government advisory bodies, and beyond. While biases can come from myriad sources, the overwhelming focus of the d...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2009.00188.x
更新日期:2009-05-01 00:00:00
abstract:CONTEXT:The presence of retail food establishments around schools can be a potentiating or protective factor for overweight in students, depending on access to these places as well as types of foods available therein. The hypothesis for this study was that a greater density and proximity of retail food establishments a...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuz110
更新日期:2020-10-01 00:00:00
abstract:CONTEXT:The impact of various dietary interventions on rheumatoid arthritis (RA), characterized by immune-inflammatory response, has been subject to increased attention. OBJECTIVE:A systematic review was conducted to update the current knowledge on the effects of nutritional, dietary supplement, and fasting interventi...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1093/nutrit/nuaa033
更新日期:2020-06-25 00:00:00
abstract::The Institute of Medicine reported in 2005 that food and beverage marketing to children and youth is "out of balance with healthful diets". The dominant policy response in the United States has been to encourage self-regulation by the food, beverage, advertising, and media industries. From a nutrition perspective, thi...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2009.00183.x
更新日期:2009-03-01 00:00:00
abstract::Milk represents a unique resource for translational medicine: It contains a rich pool of biologically active molecules with demonstrated clinical benefits. The ongoing characterization of the mechanistic process through which milk components promote development and immunity has revealed numerous milk-derived compounds...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1093/nutrit/nuv009
更新日期:2015-07-01 00:00:00
abstract::This report is the first in a series of publications resulting from the comprehensive effort being undertaken by the Food and Nutrition Board's Committee on the Scientific Evaluation of Dietary Reference Intakes and its panels and subcommittees. The history and rationale behind the development of the Dietary Reference...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.1997.tb01623.x
更新日期:1997-09-01 00:00:00
abstract::Copper transport at the cellular level is achieved by a coordinate series of interactions between passive and active membrane transport proteins, vesicles, and soluble peptides. Knowing the function of each component of this complex network has made the task of delineating the mechanism of intracellular copper homeost...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb07017.x
更新日期:2001-09-01 00:00:00
abstract::A ventilator-dependent, extremely obese adolescent patient with Prader-Willi syndrome was nutritionally managed using a parenteral, protein-sparing modified fast. A solution containing only amino acids, electrolytes, vitamins, and macro- and micro-minerals helped create a ketotic state and facilitate weaning from the ...
journal_title:Nutrition reviews
pub_type: 杂志文章
doi:10.1111/j.1753-4887.1991.tb03035.x
更新日期:1991-08-01 00:00:00
abstract::A recent study indicates that lowering homocysteine with folic acid and vitamin B6 significantly reduces the incidence of abnormal exercise electrocardiography tests and thus decreases the risk of atherosclerotic disease. Questions about study design and sample size, however, suggest that this conclusion may be premat...
journal_title:Nutrition reviews
pub_type: 杂志文章,评审
doi:10.1111/j.1753-4887.2001.tb07016.x
更新日期:2001-07-01 00:00:00