Abstract：
:In studies of glutathione (GSH) metabolism in children with severe childhood undernutrition (SCU), slower erythrocyte GSH synthesis in children with edema was associated with lower concentrations of cysteine, the rate-limiting precursor of GSH synthesis. This finding suggested a shortage of cysteine available for GSH synthesis in children with edematous SCU. The plasma concentration of methionine, the sulfur donor for cysteine synthesis, was also lower in children with edematous SCU, suggesting decreased availability of methionine for cysteine synthesis. It is also possible that reduced methionine availability will result in decreased synthesis of S-adenosylmethionine, which could lead to an overall defect in methylation reactions. This review focuses on the relationship between cysteine availability and GSH synthesis in children with SCU. It also examines whether there is an inadequate supply of cysteine in those with edematous SCU and, if so, whether this is due to a shortage of methionine due to a decreased release of methionine from protein breakdown. Finally, the review explores whether a shortage of methionine results in decreased synthesis of S-adenosylmethionine, the universal methyl donor.
journal_name
Nutr Revjournal_title
Nutrition reviewsauthors
Jahoor Fdoi
10.1111/j.1753-4887.2011.00462.xsubject
Has Abstractpub_date
2012-03-01 00:00:00pages
176-87issue
3eissn
0029-6643issn
1753-4887journal_volume
70pub_type
杂志文章,评审abstract：:The Institute of Medicine reported in 2005 that food and beverage marketing to children and youth is "out of balance with healthful diets". The dominant policy response in the United States has been to encourage self-regulation by the food, beverage, advertising, and media industries. From a nutrition perspective, thi...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2009.00183.x
更新日期：2009-03-01 00:00:00
abstract：:The national health promotion program, Health Japan 21 (second term), began in 2013. This program has set 5 basic goals: to extend healthy life expectancy and reduce health disparity, to prevent noncommunicable disease, to improve function for social life, to establish a social environment for health, and to improve l...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1093/nutrit/nuaa079
更新日期：2020-12-01 00:00:00
abstract：:Green tea, rich in antioxidant and anti-inflammatory catechins, especially epigallocatechin gallate (EGCG), has been shown to reduce surrogate markers of atherosclerosis and lipid peroxidation, particularly LDL oxidation and malondialdehyde concentrations, in several in vitro, animal, and limited clinical studies. Epi...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/nr.2007.aug.361-375
更新日期：2007-08-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2009.00221.x
更新日期：2009-08-01 00:00:00
abstract：:Both essential and nonessential dietary antioxidants have been suggested to be beneficial for health. However, studies show that many antioxidants can also exhibit prooxidant behavior under certain conditions. The antioxidant/prooxidant activity of phenolics is dependent on such factors as metal-reducing potential, ch...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1997.tb01580.x
更新日期：1997-11-01 00:00:00
abstract：:The labeling of health claims that meet the significant scientific agreement (SSA) standard (authorized health claims) and qualified health claims on conventional foods and dietary supplements requires premarket approval by the US Food and Drug Administration (FDA). FDA conducts an evidence-based review to determine w...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2007.tb00284.x
更新日期：2007-02-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2012.00524.x
更新日期：2012-11-01 00:00:00
abstract：:Fortified blended foods (FBFs) were introduced into the Food for Peace program (also known as US Public Law 480) in the 1960s. Minimal changes have since been made to their formulations. A Food Aid Quality Enhancement Project to assess the nutritional adequacy of FBFs for vulnerable populations was conducted, and the ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2010.00288.x
更新日期：2010-05-01 00:00:00
abstract：:This paper examines the speed of change in diet, activity, and obesity in the developing world, and notes potential exacerbating biological relationships that contribute to differences in the rates of change. The focus is on lower- and middle-income countries of Asia, Africa, the Middle East, and Latin America. These ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2004.tb00084.x
更新日期：2004-07-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：2014-03-01 00:00:00
abstract：:Rather than being an inevitable consequence of age, cognitive decline can occur with marked variation among individuals. In this context, nutrition is one factor that is believed to be influential. When considering the potential role of diet, two factors need to be considered. First, cognitive or brain reserve is said...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2010.00324.x
更新日期：2010-11-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/00296640260184291
更新日期：2002-07-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：1994-10-01 00:00:00
abstract：:Glucokinase plays a major role in the control of hepatic glucose uptake and storage as glycogen. Small amounts of fructose-1-phosphate, in the presence of relatively high glucose levels, markedly stimulate glucokinase through a novel mechanism of regulation involving dissociation from a regulatory protein and transloc...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1301/002966402320289377
更新日期：2002-08-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1999.tb06951.x
更新日期：1999-08-01 00:00:00
abstract：:Iodine intake influences the health of Americans today, but in different ways than it has in the past. In the early 1900s, iodine deficiency was responsible for widespread endemic goiter in the United States. The incidence of goiter was markedly reduced by the introduction of iodine supplementation of salt and other f...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1999.tb06940.x
更新日期：1999-06-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：1993-09-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1996.tb03940.x
更新日期：1996-08-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1093/nutrit/nux040
更新日期：2017-10-01 00:00:00
abstract：:Functional genomics, commonly applied to the genes and enzymes involved in metabolism of chemicals, can also be applied to enzymes involved in the metabolism of nutrients. Although in its infancy, genomics can be used to determine relationships between nutrition and toxicology, drug metabolism, and cancer. ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：2001-08-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：2011-07-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：1998-02-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：1999-09-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
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更新日期：2014-09-01 00:00:00
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journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1996.tb03933.x
更新日期：1996-07-01 00:00:00
abstract：:The regulatory properties of a principal glutamine transport system of skeletal muscle may control the balance between muscle protein synthesis and breakdown. ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.1989.tb02843.x
更新日期：1989-07-01 00:00:00
abstract：:The energy cost of daily physical activity was derived for 30 Pima Indians ages 19-71 using simultaneous measurements of total daily expenditure and basal metabolic rate in the free-living situation. The body fat of the subjects ranged from 10 to 45%. Weight-adjusted indexes of physical activity correlated negatively ...
journal_title：Nutrition reviews
pub_type： 杂志文章
doi：10.1111/j.1753-4887.1995.tb01470.x
更新日期：1995-01-01 00:00:00
abstract：:Mitochondria exert crucial physiological functions that create complex links among nutrition, health, and disease. While mitochondrial dysfunction with subsequent impairment of oxidative phosphorylation (OXPHOS) is the hallmark of the rare inherited OXPHOS diseases, OXPHOS dysfunction also plays a central role in the ...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2010.00363.x
更新日期：2011-02-01 00:00:00
abstract：:Twenty publications from twelve prospective cohorts have evaluated associations between flavonoid intakes and incidence or mortality from cardiovascular disease (CVD) among adults in Europe and the United States. The most common outcome was coronary heart disease mortality, and four of eight cohort studies reported si...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2012.00508.x
更新日期：2012-09-01 00:00:00
abstract：:Healthy humans regulate daily water balance remarkably well across their lifespan despite changes in biological development and exposure to stressors on hydration status. Acute or chronic body water deficits result when intakes are reduced or losses increase, but day-to-day hydration is generally well maintained so lo...
journal_title：Nutrition reviews
pub_type： 杂志文章,评审
doi：10.1111/j.1753-4887.2005.tb00152.x
更新日期：2005-06-01 00:00:00
