Formation and human risk of carcinogenic heterocyclic amines formed from natural precursors in meat.

Abstract:

:A group of heterocyclic amines that are mutagens and rodent carcinogens form when meat is cooked to medium and well-done states. The precursors of these compounds are natural meat components: creatinine, amino acids, and sugars. Defined model systems of dry-heated precursors mimic the amounts and proportions of heterocyclic amines found in meat. Results from model systems and cooking experiments suggest ways to reduce their formation and, thus, reduce human intake. Human cancer epidemiology studies related to the consumption of well-done meat products are listed and compared in this review.

journal_name

Nutr Rev

journal_title

Nutrition reviews

authors

Knize MG,Felton JS

doi

10.1111/j.1753-4887.2005.tb00133.x

keywords:

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

158-65

issue

5

eissn

0029-6643

issn

1753-4887

journal_volume

63

pub_type

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