Environmental enteric dysfunction and child stunting.

Abstract:

:In 2017, an estimated 1 in every 4 (23%) children aged < 5 years were stunted worldwide. With slow progress in stunting reduction in many regions and the realization that a large proportion of stunting is not due to insufficient diet or diarrhea alone, it remains that other factors must explain continued growth faltering. Environmental enteric dysfunction (EED), a subclinical state of intestinal inflammation, can occur in infants across the developing world and is proposed as an immediate causal factor connecting poor sanitation and stunting. A result of chronic pathogen exposure, EED presents multiple causal pathways, and as such the scope and sensitivity of traditional water, sanitation, and hygiene (WASH) interventions have possibly been unsubstantial. Although the definite pathogenesis of EED and the mechanism by which stunting occurs are yet to be defined, this paper reviews the existing literature surrounding the proposed pathology and transmission of EED in infants and considerations for nutrition and WASH interventions to improve linear growth worldwide.

journal_name

Nutr Rev

journal_title

Nutrition reviews

authors

Budge S,Parker AH,Hutchings PT,Garbutt C

doi

10.1093/nutrit/nuy068

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

240-253

issue

4

eissn

0029-6643

issn

1753-4887

pii

5309014

journal_volume

77

pub_type

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