Cell cycle perturbation in the hepatocytes of HCV core transgenic mice following common bile duct ligation is associated with enhanced p21 expression.

abstract：:A hybrid cell line producing monoclonal antibodies recognizing an epitope encoded by the pre-(S)2 region of hepatitis B virus (HBV) genome was obtained by fusion of mouse myeloma cells with lymphocytes from mice immunized with HBV. The monoclonal antibody Mo-F124 secreted from the hybrid line reacted with the pre-S(2)...

journal_title：Journal of medical virology

authors： Budkowska A,Riottot MM,Dubreuil P,Lazizi Y,Brechot C,Sobczak E,Petit MA,Pillot J

更新日期：1986-10-01 00:00:00

abstract：:Inosine triphosphatase (ITPA) gene variants can protect against ribavirin (RBV)-induced anemia in patients treated for chronic hepatitis C. The aim of this study was to determine the relationship between genetic variants of ITPA polymorphism, anemia, RBV dose reduction, and treatment response in hepatitis C virus (HCV...

journal_title：Journal of medical virology

authors： El Raziky M,Zayed NA,Abdel Baki A,Mansour SA,Shahin RMH

更新日期：2017-10-01 00:00:00

abstract：:SARS-COV-2 (COVID-19) is a novel virus that has caused over 28 million cases worldwide and over 900,000 deaths since early 2020, rightfully being classified as a pandemic. COVID-19 is diagnosed via PCR testing which looks at cycle threshold values of two genes, N2 and E. This study examined cycle threshold values of C...

journal_title：Journal of medical virology

authors： Seeni R,Firzli T,Riddle MS,Krasner C,Ashraf S,Siddiqui F

更新日期：2021-02-02 00:00:00

abstract：:To assess whether the administration of a booster dose of influenza vaccine may enhance immune response in hemodialysis patients, 58 subjects were given two doses of the 2003/2004 season influenza vaccine, 1 month apart. "European Agency for the Evaluation of Medicinal Products" (EMEA) criteria were fully met in terms...

journal_title：Journal of medical virology

authors： Tanzi E,Amendola A,Pariani E,Zappa A,Colzani D,Logias F,Perego A,Zanetti AR

更新日期：2007-08-01 00:00:00

abstract：:Fifty-three (96%) of 55 patients with coronary artery stenosis were positive for serum anti-HHV-6 IgG, and 50 (91%) of these patients had anti-HHV-7 IgG. The number of cases sero-positive for HHV-6 and -7 in the 54 age matched control volunteers was 52 (96%) and 53 (98%), respectively. No statistical difference in the...

journal_title：Journal of medical virology

authors： Ihira M,Yoshikawa T,Ishii J,Nomura M,Hishida H,Ohashi M,Enomoto Y,Suga S,Iida K,Saito Y,Nishiyama Y,Asano Y

更新日期：2002-08-01 00:00:00

abstract：:A panel of deoxyoligonucleotide probes for studying the genetic variability and genotyping of Tick-borne encephalitis virus (TBEV) strains by molecular hybridization of nucleic acids (MHNA) was created. This panel allows to estimate the genetic structure of individual TBEV strains, as the targets for probes are both v...

journal_title：Journal of medical virology

authors： Demina TV,Dzhioev YP,Verkhozina MM,Kozlova IV,Tkachev SE,Plyusnin A,Doroshchenko EK,Lisak OV,Zlobin VI

更新日期：2010-05-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is a major cause of morbidity and mortality in immunocompromised patients, such as renal transplant recipients. Analysis of the gene encoding the envelope glycoprotein B (gB) showed that clinical isolates adopted one of the sequence configurations, permitting the isolates to be assigned a ...

journal_title：Journal of medical virology

authors： Carraro E,Granato CF

更新日期：2003-06-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:GII.b norovirus is an obligatory recombinant with an open reading frame (ORF) 1 comprising the GII.b genotype and the ORF 2 region corresponding to one of a number of other norovirus genotypes. GII.b is the second most common genotype after GII.4 associated with gastroenteritis outbreaks in Victoria, Australia. The st...

journal_title：Journal of medical virology

authors： Bruggink LD,Marshall JA

更新日期：2013-08-01 00:00:00

abstract：:In vitro incubation of human cytomegalovirus (Towne strain) with 8 U/ml human recombinant myeloperoxidase plus sodium chloride and glucose nearly abolished viral infectivity. To assay the effect on intracellular infection, cell toxicity of the enzymes was first studied. Even the high dose of 16 U/ml of recombinant mye...

journal_title：Journal of medical virology

authors： El Messaoudi K,Verheyden AM,Thiry L,Fourez S,Tasiaux N,Bollen A,Moguilevsky N

更新日期：2002-02-01 00:00:00

abstract：:Human papillomavirus (HPV) is a carcinogenic agent responsible for tumor development in many sexually involved tissues. We present a survey on the prevalence of HPV infection in a risk population for sexually transmitted infections (STIs). The studied population was formed by 125 STI clinic attendees, who took part in...

journal_title：Journal of medical virology

authors： Ciccarese G,Herzum A,Rebora A,Drago F

更新日期：2017-06-01 00:00:00

abstract：:Junin virus infection in guinea pigs is known to be similar to human Argentine hemorrhagic fever (AHF). The guinea pig was chosen as a model for transplacental transmission of Junin virus, as both guinea pig and man have a similar placental structure. Pregnant guinea pigs were infected with the pathogenic XJ strain of...

journal_title：Journal of medical virology

authors： Sangiorgio P,Weissenbacher MC

更新日期：1983-01-01 00:00:00

abstract：:Human herpesviruses (HHVs) are involved in the pathogenesis of different types of uveitis. Cytokine response plays an important role in virus-induced immunopathology. This study aimed to investigate the incidence of HHVs in aqueous humor samples of immunocompetent patients with suspected viral uveitis and cytokine (IL...

journal_title：Journal of medical virology

authors： Nahdi I,Abdelwahed RB,Boukoum H,Bressollette-Bodin C,Attia S,Yahia SB,Fisson S,Khairallah M,Aouni M

更新日期：2013-12-01 00:00:00

abstract：:Polyomavirus BK (BKV) is a common human polyomavirus that rarely causes clinical symptoms in immunocompetent individuals. However, BK virus reactivation occurs in 20-40% of kidney transplant patients and 1-10% of cases present with BK virus-associated nephropathy (BKVN) and reduced kidney allograft survival. In this s...

journal_title：Journal of medical virology

authors： Girmanova E,Brabcova I,Bandur S,Hribova P,Skibova J,Viklicky O

更新日期：2011-08-01 00:00:00

abstract：:The prevalence of delta agent among 120 Chinese patients with HBsAg-positive chronic active and hepatocellular carcinoma from Taiwan and Los Angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. Of 120 patients, only four with chr...

journal_title：Journal of medical virology

authors： Govindarajan S,Lee SD,Tong MJ,Tsai YT,Lo KJ

更新日期：1984-01-01 00:00:00

abstract：:An epidemiological and molecular study of hepatitis C virus (HCV) infection was carried out in Brazilian hemodialysis centers. A total of 1,095 patients in all 15 hemodialysis centers in the State of Goiás, Brazil, were studied. All patients were interviewed for possible risk factors to HCV infection and serum samples...

journal_title：Journal of medical virology

authors： Carneiro MA,Teles SA,Lampe E,Espírito-Santo MP,Gouveia-Oliveira R,Reis NR,Yoshida CF,Martins RM

更新日期：2007-09-01 00:00:00

abstract：:Genetically different subpopulations were identified and purified from Japanese Encephalitis virus (JEV). Those with small plaques (SPs; <2 mm in diameter), derived from strains of T1P1, CJN, and CC27, were more competent than those with large plaques (LPs; >5 mm in diameter) when passaged in Neuro-2a cells. Differenc...

journal_title：Journal of medical virology

authors： Chiou SS,Liu H,Chuang CK,Lin CC,Chen WJ

更新日期：2005-08-01 00:00:00

abstract：:Hepatitis E virus (HEV) infection is a significant public health issue in many developing countries, causing waterborne outbreaks as well as sporadic hepatitis. We report here an outbreak of HEV genotype 1f infection during April-May 2018 among people living at Halisohor, a low land in the southern part of Chottogram ...

journal_title：Journal of medical virology

authors： Baki AA,Haque W,Giti S,Khan AA,Rahman MM,Jubaida N,Rahman M

更新日期：2020-12-17 00:00:00

abstract：:Inoue-Melnick virus (IMV) was stabilized to thermal inactivation at 50 degrees C by 1 M Na2SO4 but not by 1 M MgCl2, 1 M MgSO4, 2 M NaCl, and 2 M KCl. The latter salts enhanced the inactivation over that in distilled water. Na2SO4 stabilized IMV at 1 M concentration but enhanced inactivation at 0.1 M. Three types of I...

journal_title：Journal of medical virology

authors： Nishibe Y,Inoue YK,Melnick JL

更新日期：1986-10-01 00:00:00

abstract：:The effect of different formulations of interferon on therapeutic response in patients coinfected with HIV and HCV is unclear. In this study, the safety, tolerability, viral kinetics (VK) modeling and host responses among HIV/HCV coinfected patients treated with pegylated-IFN or albinterferon alfa-2b (AlbIFN) with wei...

journal_title：Journal of medical virology

authors： Osinusi A,Bon D,Nelson A,Lee YJ,Poonia S,Shivakumar B,Cai SY,Wood B,Haagmans B,Lempicki R,Herrmann E,Sneller M,Polis M,Masur H,Kottilil S

更新日期：2014-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a single-stranded RNA virus related to the Flaviviridae family, and striking nucleotide sequence diversity has been reported among HCV isolates from different geographic areas. To study the distribution HCV genotypes among disease group in Korea, we subtyped HCV using the method of Okamoto e...

journal_title：Journal of medical virology

authors： Lee DS,Sung YC,Whang YS

更新日期：1996-05-01 00:00:00

abstract：:The seroprevalence of hepatitis A antibodies in travellers attending London Travel Clinics increases with age and screening may eliminate the need for vaccination at present for approximately 40% of adults. The duration of protection by current hepatitis A vaccine(s) is still to be established. ...

journal_title：Journal of medical virology

authors： Zuckerman JN,Powell L

更新日期：1994-12-01 00:00:00

abstract：:An enzyme-linked immunosorbent assay (ELISA) test using polyvalent antigens and antisera was used to detect Coxsackie B virus-specific IgM responses in 329 patients admitted to the Coronary Care Unit, Wellington Hospital, New Zealand over a 12-month period. The sera of 30 of 153 (19.6%) patients with acute myocardial ...

journal_title：Journal of medical virology

authors： Lau RC

更新日期：1986-02-01 00:00:00

abstract：:The human cytomegalovirus (HCMV), a member of the Herpesviridae, is the most frequent cause of congenital virus infections and a major cause of morbidity and mortality in immunocompromised patients. Due to the lack of an appropriate animal model, insight into the pathogenesis of HCMV infections originates primarily fr...

journal_title：Journal of medical virology

authors： Bissinger AL,Sinzger C,Kaiserling E,Jahn G

更新日期：2002-06-01 00:00:00

abstract：:It has been reported that a new pattern of mutations, E44D/A and/or V118I, in the reverse transcriptase (RT) gene of HIV-1 confers a moderate level of resistance to lamivudine in the absence of the M184V mutation. The prevalence of this mutational pattern was studied in HIV-1 isolates obtained from 280 patients. These...

journal_title：Journal of medical virology

authors： Montes B,Segondy M

更新日期：2002-03-01 00:00:00

abstract：:Group C rotavirus (RVC) is potentially an important pathogen associated with acute gastroenteritis (AG), especially in outbreaks. This study aims to detect and molecularly characterize RVC in hospitalized children with AG in Belém, Brazil. From May 2008 to April 2011, 279 stools were subjected to reverse-transcription...

journal_title：Journal of medical virology

authors： Lobo Pdos S,Guerra Sde F,Siqueira JA,Soares Lda S,Gabbay YB,Linhares AC,Mascarenhas JD

更新日期：2016-04-01 00:00:00

abstract：:An EBV type 1 variant strain was detected in two Turkish siblings (boy and girl), who both suffered and died from similar progressive Epstein-Barr virus (EBV)-associated lymphoproliferative disease. Molecular characterisation of this EBV isolate revealed a 51bp-deletion and six nucleotide changes within the Epstein-Ba...

journal_title：Journal of medical virology

authors： Schuster V,Seidenspinner S,Kreth HW

更新日期：1996-01-01 00:00:00

abstract：:Human T-cell lymphotropic virus (HTLV) antibody screening is not recommended uniformly before transplantation in Western countries. In the year 2001, the first cases of HTLV-I infection acquired through organ transplantation from one asymptomatic carrier were reported in Europe. All three organ recipients developed a ...

journal_title：Journal of medical virology

authors： Toro C,Benito R,Aguilera A,Bassani S,Rodríguez C,Calderón E,Caballero E,Alvarez P,García J,Rodríguez-Iglesias M,Guelar A,del Romero J,Soriano V,HTLV Spanish Study Group.

更新日期：2005-06-01 00:00:00

abstract：:Fifty-six renal allograft recipients were studied prospectively for 3 months or longer after transplant. The polymerase chain reaction (PCR) was used to screen peripheral blood leucocyte (PBL) specimens for CMV, human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7) DNA (DNAemia) in 67 healthy controls and in seria...

journal_title：Journal of medical virology

authors： Osman HK,Peiris JS,Taylor CE,Warwicker P,Jarrett RF,Madeley CR

更新日期：1996-04-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection is an important risk factor for atherosclerosis (AS). Numerous studies have been conducted to analyze the association between HCMV infection and risk of AS, but no clear consensus has been reached. So the objective of this paper was aimed to demonstrate the relationship between H...

journal_title：Journal of medical virology

authors： Jia YJ,Liu J,Han FF,Wan ZR,Gong LL,Liu H,Zhang W,Wardell T,Lv YL,Liu LH

更新日期：2017-12-01 00:00:00