Phylogenetic analysis of human group C rotavirus in hospitalized children with gastroenteritis in Belém, Brazil.

Abstract:

:Group C rotavirus (RVC) is potentially an important pathogen associated with acute gastroenteritis (AG), especially in outbreaks. This study aims to detect and molecularly characterize RVC in hospitalized children with AG in Belém, Brazil. From May 2008 to April 2011, 279 stools were subjected to reverse-transcription polymerase chain reaction targeting VP7, VP6, VP4, and NSP4 genes. RVC positivity rate was 2.1% (6/279) and phylogenetic analysis of positive samples yields genotype G4-P[2]-I2-E2. No evidence of zoonotic transmission and VP7 gene demonstrated close relationship with Asian strains. RVC surveillance is worth to expand information on evolutionary and epidemiological features of this virus.

journal_name

J Med Virol

authors

Lobo Pdos S,Guerra Sde F,Siqueira JA,Soares Lda S,Gabbay YB,Linhares AC,Mascarenhas JD

doi

10.1002/jmv.24379

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

728-33

issue

4

eissn

0146-6615

issn

1096-9071

journal_volume

88

pub_type

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