The complete genome sequence of foot-and-mouth disease virus O/Akesu/58 strain and its some molecular characteristics.

Abstract:

:The complete genome of O/Akesu/58 strain of foot-and-mouth disease virus (FMDV) was sequenced. The phylogenetic analysis revealed that it is not closely related to epidemic strains or previous strains compared with reference sequences (the identities of complete VP1 nucleotide sequences range from 77.5 to 84.0%). Its cell-receptor-binding site is a SGD (Ser-Gly-Asp) motif instead of RGD (Arg-Gly-Asp), and 43 bases were deleted in PKs region of the 5'UTR, although deletions were not found in other gene regions.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Li D,Liu ZX,Bao HF,Lu ZJ,Guo JH,Cao YM,Li PH,Bai XW,Chen YL,Xie BX,Cai XP,Xie QG

doi

10.1007/s00705-007-1041-y

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

2079-85

issue

11

eissn

0304-8608

issn

1432-8798

journal_volume

152

pub_type

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