Controlled synthesis and inclusion ability of a hyaluronic acid derivative bearing beta-cyclodextrin molecules.

abstract：:Injectable hydrogels based on extracellular matrix-derived polymers show much promise in the field of tissue engineering and regenerative medicine. However, the hydrogels reported to date have at least one characteristic that limits their potential for clinical use, such as excessive swelling, complicated and potentia...

journal_title：Biomacromolecules

authors： Pupkaite J,Rosenquist J,Hilborn J,Samanta A

更新日期：2019-09-09 00:00:00

abstract：:PolyHIPEs show great promise as tissue engineering scaffolds due to the tremendous control of pore size and interconnectivity afforded by this technique. Highly porous, fully biodegradable scaffolds were prepared by polymerization of the continuous phase of high internal phase emulsions (HIPEs) containing the macromer...

journal_title：Biomacromolecules

authors： Christenson EM,Soofi W,Holm JL,Cameron NR,Mikos AG

更新日期：2007-12-01 00:00:00

abstract：:Despite the good clinical efficacy of interferon-alpha (IFNα) to treat some types of cancer and viral infections, this biological drug is underused given its severe adverse effects and high dosing parenteral regimens. Aiming to achieve a breakthrough in therapy with IFNα, this work reports for the first time on the de...

journal_title：Biomacromolecules

authors： Cánepa C,Imperiale JC,Berini CA,Lewicki M,Sosnik A,Biglione MM

更新日期：2017-10-09 00:00:00

abstract：:The objective of this study was to explore the use of reverse thermo-responsive (RTG) polymers for generating implants at their site of performance, following minimally invasive surgical procedures. Aiming at combining syringability and enhanced mechanical properties, a new family of injectable RTG-displaying polymers...

journal_title：Biomacromolecules

authors： Cohn D,Sosnik A,Garty S

更新日期：2005-05-01 00:00:00

abstract：:Orb-weaving spider silk fibers are assembled from very large, highly repetitive proteins. The repeated segments contain, in turn, short, simple, and repetitive amino acid motifs that account for the physical and mechanical properties of the assembled fiber. Of the six orb-weaver silk fibroins, the piriform silk that m...

journal_title：Biomacromolecules

authors： Perry DJ,Bittencourt D,Siltberg-Liberles J,Rech EL,Lewis RV

更新日期：2010-11-08 00:00:00

abstract：:Although composed simply of glucose polymers, the starch granule is a complex, semicrystalline structure. Much of this complexity arises from the fact that the two primary enzymes of synthesis-starch synthase and starch-branching enzyme-exist as multiple isoforms. Each form has distinct properties and plays a unique r...

journal_title：Biomacromolecules

authors： Smith AM

更新日期：2001-07-01 00:00:00

abstract：:The C-termini of Spidroins produced in the major and minor ampullate glands of spiders are highly conserved. Despite this conservation, no corresponding peptides have been identified in the spinning dopes or the silk filaments so far. To prove their presence or absence, polyclonal antibodies derived against fusion pro...

journal_title：Biomacromolecules

authors： Sponner A,Unger E,Grosse F,Weisshart K

更新日期：2004-05-01 00:00:00

abstract：:Optimal curcumin delivery for medicinal applications requires a drug delivery system that both solubilizes curcumin and prevents degradation. To achieve this, curcumin has been encapsulated in submicrometer chitosan/Tween 20 particles via a benchtop spray-drying process. Spray-drying parameters have been optimized usi...

journal_title：Biomacromolecules

authors： O'Toole MG,Henderson RM,Soucy PA,Fasciotto BH,Hoblitzell PJ,Keynton RS,Ehringer WD,Gobin AS

更新日期：2012-08-13 00:00:00

abstract：:Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and tissue homeostasis. Here, we demonstrate supramolecular GAG-like glycopeptide nanofibers mimicking bioactive functions of natural hyaluronic acid molecules. Sel...

journal_title：Biomacromolecules

authors： Ustun Yaylaci S,Sardan Ekiz M,Arslan E,Can N,Kilic E,Ozkan H,Orujalipoor I,Ide S,Tekinay AB,Guler MO

更新日期：2016-02-08 00:00:00

abstract：:The mucilaginous viscin tissue within mistletoe berries possesses an extraordinary ability to be rapidly processed under ambient conditions into stiff cellulosic fibers (>14 GPa) through simple mechanical drawing. This rapid and extreme transformation process is hydration-dependent and involves an astonishing >200-fol...

journal_title：Biomacromolecules

authors： Horbelt N,Eder M,Bertinetti L,Fratzl P,Harrington MJ

更新日期：2019-08-12 00:00:00

abstract：:Their physicochemical properties and relatively low cost make cellulose nanocrystals (CNCs) a potential candidate for future large-scale production in many fields including nanomedicine. Prior to a sustained and responsible development as theranostic agents, robust and reliable data concerning their safety, biocompati...

journal_title：Biomacromolecules

authors： Colombo L,Zoia L,Violatto MB,Previdi S,Talamini L,Sitia L,Nicotra F,Orlandi M,Salmona M,Recordati C,Bigini P,La Ferla B

更新日期：2015-09-14 00:00:00

abstract：:Mixed protein-based hydrogels have been prepared by blending gelatin (G) with amorphous Bombyx mori silk fibroin (SF) and promoting beta-crystallization of SF via subsequent exposure to methanol or methanol/water solutions. The introduction of beta crystals in SF serves to stabilize the hydrogel network and extend the...

journal_title：Biomacromolecules

authors： Gil ES,Frankowski DJ,Spontak RJ,Hudson SM

更新日期：2005-11-01 00:00:00

abstract：:Chitosan possesses many characteristics of an ideal gene delivery system. However, the transfection efficiency of conventional chitosans is generally found to be low. In this study, we investigated the self-branching of chitosans as a strategy to improve its gene transfer properties without compromising its safety pro...

journal_title：Biomacromolecules

authors： Malmo J,Vårum KM,Strand SP

更新日期：2011-03-14 00:00:00

abstract：:The conformational behavior of a long single-chain double-stranded DNA in solutions of free silver ions and silver nanoparticles generated via the reduction of AgNO3 by NaBH4 was monitored by fluorescence and electron microscopies and UV spectroscopy. The interaction of monovalent silver ions with DNA induces shrinkin...

journal_title：Biomacromolecules

authors： Zinchenko AA,Baigl D,Chen N,Pyshkina O,Endo K,Sergeyev VG,Yoshikawa K

更新日期：2008-07-01 00:00:00

abstract：:We have found that dialysis of 5 mg/mL collagen solution into the phosphate solution with a pH of 7.1 and an ionic strength of 151 mM [corrected] at 25 °C results in a collagen gel with a birefringence and tubular pores aligned parallel to the growth direction of the gel. The time course of averaged diameter of tubula...

journal_title：Biomacromolecules

authors： Furusawa K,Sato S,Masumoto J,Hanazaki Y,Maki Y,Dobashi T,Yamamoto T,Fukui A,Sasaki N

更新日期：2012-01-09 00:00:00

abstract：:Hybrid dendritic-linear block copolymers based on a 4-arm poly(ethylene glycol) (PEG) core were synthesized using an accelerated AB2/CD2 dendritic growth approach through orthogonal amine/epoxy and thiol-yne chemistries. The biological activity of these 4-arm and the corresponding 2-arm hybrid dendrimers revealed an e...

journal_title：Biomacromolecules

authors： Albertazzi L,Mickler FM,Pavan GM,Salomone F,Bardi G,Panniello M,Amir E,Kang T,Killops KL,Bräuchle C,Amir RJ,Hawker CJ

更新日期：2012-12-10 00:00:00

abstract：:G-quadruplex is a type of DNA secondary structure formed by specific guanine-rich sequences. Because of their enrichment in functional genomic regions and their biological significance, G-quadruplexes are recognized as significant drug targets for cancer and other diseases. Here, we tested the precipitation efficiency...

journal_title：Biomacromolecules

authors： Lin J,Yan YY,Ou TM,Tan JH,Huang SL,Li D,Huang ZS,Gu LQ

更新日期：2010-12-13 00:00:00

abstract：:We present a synthetic approach toward soft, glycooligomer-functionalized microgel particles mimicking carbohydrate presenting cell surfaces and analyze their specific binding to a model lectin (Concanavalin A, ConA). Focusing on multivalent presentation, a series of sequence-controlled glycooligomers with varying spa...

journal_title：Biomacromolecules

authors： Jacobi F,Camaleño de la Calle A,Boden S,Grafmüller A,Hartmann L,Schmidt S

更新日期：2018-08-13 00:00:00

abstract：:A novel cellulose derivative, 6-O-dihydrophytylcellulose (DHPC), was first synthesized via a ring-opening polymerization and allowed to self-assemble onto an air-water interface. Langmuir-Blodgett (LB) films were characterized with atomic force microscope (AFM), UV-vis spectroscopy, and Fourier transform infrared spec...

journal_title：Biomacromolecules

authors： Sakakibara K,Ifuku S,Tsujii Y,Kamitakahara H,Takano T,Nakatsubo F

更新日期：2006-06-01 00:00:00

abstract：:In this study, we demonstrate for the first time the fabrication of carboxylated chitosan nanocrystals (ChsNC) with high degree of deacetylation (DDA) at >80% and narrow size distribution. We also studied its application as a sustainable support material for metal-based catalysts. Carboxylated chitin nanocrystals (ChN...

journal_title：Biomacromolecules

authors： Jin T,Kurdyla D,Hrapovic S,Leung ACW,Régnier S,Liu Y,Moores A,Lam E

更新日期：2020-06-08 00:00:00

abstract：:Wheat arabinoxylan was treated with two α-arabinofuranosidases exhibiting different mode of action to create three different polymeric substrates. These three substrate preparations were characterized by xylopyranose backbone sugars that are (1) singly substituted by arabinose at C2 or C3, (2) doubly substituted by ar...

journal_title：Biomacromolecules

authors： Littunen K,Mai-Gisondi G,Seppälä J,Master ER

更新日期：2017-05-08 00:00:00

abstract：:Poly(3-(tert-butoxycarbonyl)-N-vinyl-2-pyrrolidone) has been synthesized and characterized by gel permeation chromatography, Fourier transform infrared spectroscopy, NMR spectroscopy, and thermal analysis. The polymer is a chemically amplified photoresist. Arrays of lines with 25 microm width and 25 microm spacing wer...

journal_title：Biomacromolecules

authors： He W,Gonsalves KE,Pickett JH,Halberstadt C

更新日期：2003-01-01 00:00:00

abstract：:Ephemeral gels, called Enzgels, successively undergo sol-gel and then gel-sol transition under the action of two antagonistic enzymes, transglutaminase and protease. Molecular and macroscopic properties of Enzgels are directly dependent on the enzymatic activities and their ratios. This work studies the characteristic...

journal_title：Biomacromolecules

authors： Picard J,Giraudier S,Larreta-Garde V

更新日期：2008-01-01 00:00:00

abstract：:The aggregation of meso-tetra(4-sulfonatophenyl)porphyrin (H(2)TPPS(4-)) in phosphate solutions was investigated as a function of pH, concentration, time, ionic strength, and solution preparation (either from dilution of a freshly prepared 2 mM stock or by direct preparation of μM solution concentrations) using a comb...

journal_title：Biomacromolecules

authors： Hollingsworth JV,Richard AJ,Vicente MG,Russo PS

更新日期：2012-01-09 00:00:00

abstract：:Softwood and hardwood celluloses were oxidized by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation. The TEMPO-oxidized cellulose fibers were converted to transparent dispersions in water, which consisted of individual nanofibers 3-4 nm in width. Films were then prepared from the TEMPO-oxidized c...

journal_title：Biomacromolecules

authors： Fukuzumi H,Saito T,Iwata T,Kumamoto Y,Isogai A

更新日期：2009-01-12 00:00:00

abstract：:Amyloid-like fibrils are prepared from protein in the lab by controlled heat treatments, yet these must be further assembled to match the desirable mechanical and structural properties of biological fibers. Here, β-lactoglobulin fibrils were incorporated into poly(ethylene oxide) fibers of 40-180 nm diameter by electr...

journal_title：Biomacromolecules

authors： Chen D,Narayanan N,Federici E,Yang Z,Zuo X,Gao J,Fang F,Deng M,Campanella OH,Jones OG

更新日期：2020-07-13 00:00:00

abstract：:Alditol bearing chitosans have shown the ability to reduce silver ions in mild conditions and without addition of exogenous reducing agents. The ion reduction induces the formation of a lactone moiety on the polysaccharide (Fetizon reaction) without causing C-C bond cleavage on the polyol. The close and multivalent ar...

journal_title：Biomacromolecules

authors： Donati I,Travan A,Pelillo C,Scarpa T,Coslovi A,Bonifacio A,Sergo V,Paoletti S

更新日期：2009-02-09 00:00:00

abstract：:Oriented immobilization of proteins is an important step in creating protein-based functional materials. In this study, a method was developed to orient proteins on hydroxyapatite (HA) surfaces, a widely used bone implant material, to improve protein bioactivity by employing enhanced green fluorescent protein (EGFP) a...

journal_title：Biomacromolecules

authors： Yewle JN,Wei Y,Puleo DA,Daunert S,Bachas LG

更新日期：2012-06-11 00:00:00

abstract：:As a first step toward utilizing self-assembling peptide scaffolds to create tunable matrices for drug delivery, peptide RADAFI and RADAFII, containing the same amino acid composition but different positions of one phenylalanine residue, scaffolds were prepared for controlled release of chiral enantiomers. The release...

journal_title：Biomacromolecules

authors： Zhao Y,Tanaka M,Kinoshita T,Higuchi M,Tan T

更新日期：2009-12-14 00:00:00

abstract：:Textile chitosan fiber scaffolds were developed and tested in terms of biocompatibility for human bone marrow stromal cells (hBMSCs). A part of the scaffolds was further modified by coating with fibrillar collagen type I in order to biologize the surface. hBMSCs of two donors were used for cell culture experiments in ...

journal_title：Biomacromolecules

authors： Heinemann C,Heinemann S,Lode A,Bernhardt A,Worch H,Hanke T

更新日期：2009-05-11 00:00:00