Unraveling the Rapid Assembly Process of Stiff Cellulosic Fibers from Mistletoe Berries.

abstract：:The structure of an extracellular polysaccharide (EPS) from Streptococcus thermophilus THS has been determined. A combination of component analysis, methylation analysis and NMR spectroscopy shows that the polysaccharide is composed of pentasaccharide repeating units. Sequential information was obtained by two-dimensi...

journal_title：Biomacromolecules

authors： Nordmark EL,Yang Z,Huttunen E,Widmalm G

更新日期：2005-01-01 00:00:00

abstract：:A well-defined fluorescent conjugated polyfluorene with pendant lactopyranosyl ligands was easily prepared through Cu(I)-catalyzed azide/alkyne "click" ligation and Suzuki coupling polymerization. As a fluorescent multivalent model system of glycoconjugates, the polymer was first used for studies of metal ion-mediated...

journal_title：Biomacromolecules

authors： Chen Q,Cui Y,Zhang TL,Cao J,Han BH

更新日期：2010-01-11 00:00:00

abstract：:The maintenance of hepatocyte phenotype and functions remains as a great challenge in the generation of functional liver tissue and in vitro model for drug metabolism studies. The use of hepatocyte coculture systems plays essential roles in the establishment of cell-cell and cell-extracellular matrix communications si...

journal_title：Biomacromolecules

authors： Liu Y,Li H,Yan S,Wei J,Li X

更新日期：2014-03-10 00:00:00

abstract：:The purpose of this study is to investigate the combined effects of oxygen plasma treatments and silver nanoparticles (Ag) on PLGA in order to modulate the surface antimicrobial properties through tunable bacteria adhesion mechanisms. PLGA nanocomposite films, produced by solvent casting with 1 wt % and 7 wt % of Ag n...

journal_title：Biomacromolecules

authors： Fortunati E,Mattioli S,Visai L,Imbriani M,Fierro JL,Kenny JM,Armentano I

更新日期：2013-03-11 00:00:00

abstract：:Their physicochemical properties and relatively low cost make cellulose nanocrystals (CNCs) a potential candidate for future large-scale production in many fields including nanomedicine. Prior to a sustained and responsible development as theranostic agents, robust and reliable data concerning their safety, biocompati...

journal_title：Biomacromolecules

authors： Colombo L,Zoia L,Violatto MB,Previdi S,Talamini L,Sitia L,Nicotra F,Orlandi M,Salmona M,Recordati C,Bigini P,La Ferla B

更新日期：2015-09-14 00:00:00

abstract：:The drying dynamics of protein coatings is of importance for many applications. The main focus of research so far was to investigate macroscopic properties of protein coatings, leaving drying dynamics virtually unexplored. A unique combination of techniques is used to monitor drying of a coating containing the protein...

journal_title：Biomacromolecules

authors： Bouman J,de Vries R,Venema P,Belton P,Baukh V,Huinink HP,van der Linden E

更新日期：2015-01-12 00:00:00

abstract：:Electrochemically controlled, reversible assembly of biopolymers into hydrogel structures is a promising technique for on-demand cell or drug encapsulation and release systems. An electrochemically sol-gel transition has been demonstrated in regenerated Bombyx mori silk fibroin, offering a controllable way to generate...

journal_title：Biomacromolecules

authors： Lin Y,Xia X,Shang K,Elia R,Huang W,Cebe P,Leisk G,Omenetto F,Kaplan DL

更新日期：2013-08-12 00:00:00

abstract：:We have designed, synthesized, and characterized peptides containing four repeats of the sequences VAALEKE (peptide E) or VAALKEK (peptide K). While the peptides alone adopt in aqueous solutions a random coil conformation, their equimolar mixture forms heterodimeric coiled coils as confirmed by CD spectroscopy. 5-Azid...

journal_title：Biomacromolecules

authors： Pechar M,Pola R,Laga R,Ulbrich K,Bednárová L,Maloň P,Sieglová I,Král V,Fábry M,Vaněk O

更新日期：2011-10-10 00:00:00

abstract：:Polymerized high internal phase emulsions (polyHIPEs) have been utilized in the creation of injectable scaffolds that cure in situ to fill irregular bone defects and potentially improve tissue healing. Previously, thermally initiated scaffolds required hours to cure, which diminished the potential for clinical transla...

journal_title：Biomacromolecules

authors： Moglia RS,Whitely M,Dhavalikar P,Robinson J,Pearce H,Brooks M,Stuebben M,Cordner N,Cosgriff-Hernandez E

更新日期：2014-08-11 00:00:00

abstract：:Two poly(amido-amine)s (oligoPAM and oligoNER) containing bis-phosphonate residues were obtained by a Michael-type polyaddition of pamidronate and neridronate to 1,4-bis(acryloyl)piperazine. The SEC (size-exclusion chromatography) and the MALDI-TOF (matrix assisted laser desorption ionization) analyses were consistent...

journal_title：Biomacromolecules

authors： Casolaro M,Casolaro I,Spreafico A,Capperucci C,Frediani B,Marcolongo R,Margiotta N,Ostuni R,Mendichi R,Samperi F,Ishii T,Ito Y

更新日期：2006-12-01 00:00:00

abstract：:Well-defined linear poly(acryloyl glucosamine) (PAGA) exhibiting molar masses ranging from 3 to 120 K and low polydispersities have been prepared via reversible addition-fragmentation chain transfer polymerization (RAFT) in aqueous solution without recourse to protecting group chemistry. The livingness of the process ...

journal_title：Biomacromolecules

authors： Bernard J,Hao X,Davis TP,Barner-Kowollik C,Stenzel MH

更新日期：2006-01-01 00:00:00

abstract：:Despite the good clinical efficacy of interferon-alpha (IFNα) to treat some types of cancer and viral infections, this biological drug is underused given its severe adverse effects and high dosing parenteral regimens. Aiming to achieve a breakthrough in therapy with IFNα, this work reports for the first time on the de...

journal_title：Biomacromolecules

authors： Cánepa C,Imperiale JC,Berini CA,Lewicki M,Sosnik A,Biglione MM

更新日期：2017-10-09 00:00:00

abstract：:Anionic copolymer systems containing sulfated monomers have great potential for delivery of cationic therapeutics, but N-isopropylacrylamide (NIPAm) 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) copolymer nanoparticles have seen limited characterization to date with regard to physical properties relevant to load...

journal_title：Biomacromolecules

authors： Bartlett RL 2nd,Medow MR,Panitch A,Seal B

更新日期：2012-04-09 00:00:00

abstract：:The objective of this study is to investigate the influence of point mutations on the structural stability of coiled coil fragments of the human hair intermediate filament by molecular dynamics simulations and free energy calculations. Mutations in the helix termination motif of human hair keratin gene hHb6 seem to be...

journal_title：Biomacromolecules

authors： Danciulescu C,Nick B,Wortmann FJ

更新日期：2004-11-01 00:00:00

abstract：:Although the field of cancer immunotherapy is intensively investigated, there is still a need for generic strategies that allow easy, mild and efficient formulation of vaccine antigens. Here we report on a generic polymer-protein ligation strategy to formulate protein antigens into reversible polymeric conjugates for ...

journal_title：Biomacromolecules

authors： Lybaert L,Vanparijs N,Fierens K,Schuijs M,Nuhn L,Lambrecht BN,De Geest BG

更新日期：2016-03-14 00:00:00

abstract：:Bacterial biofilms tolerate extreme levels of antibiotics. Treatment of biofilm infections therefore requires the development of new or modified antimicrobials that can penetrate biofilms and are effective against dormant persistent cells. One such new approach uses the biodegradable biopolymer chitosan and its deriva...

journal_title：Biomacromolecules

authors： Sahariah P,Másson M,Meyer RL

更新日期：2018-09-10 00:00:00

abstract：:This study describes the formulation and physicochemical characterization of poly(acrylic acid) (PAA) organogels, designed as bioactive implants for improved treatment of infectious diseases of the oral cavity. Organogels were formulated containing a range of concentrations of PAA (3-10% w/w) and metronidazole (2 or 5...

journal_title：Biomacromolecules

authors： Jones DS,Muldoon BC,Woolfson AD,Andrews GP,Sanderson FD

更新日期：2008-02-01 00:00:00

abstract：:A novel pH-sensitive amphiphilic copolymer brush poly(methyl methacrylate-co-methacrylic acid)-b-poly(poly(ethylene glycol) methyl ether monomethacrylate) [P(MMA-co-MAA)-b-PPEGMA] was defined and synthesized by atom transfer radical polymerization (ATRP) technique. The molecular structures and characteristics of this ...

journal_title：Biomacromolecules

authors： Yang YQ,Zheng LS,Guo XD,Qian Y,Zhang LJ

更新日期：2011-01-10 00:00:00

abstract：:The purpose of this study was to gain mechanistic insights into the effect of different formulation parameters on the degradation and release behavior of protein-loaded nanoparticulate carrier systems based on an aliphatic polyester with pendant hydroxyl groups, poly(lactic-co-glycolic-hydroxymethyl glycolic acid) (pL...

journal_title：Biomacromolecules

authors： Samadi N,van Nostrum CF,Vermonden T,Amidi M,Hennink WE

更新日期：2013-04-08 00:00:00

abstract：:Chitosan is a linear cationic biopolymer composed of glucosamine and N-acetyl-glucosamine that is only soluble in acidic aqueous solutions and precipitates when neutralized. However, it was recently discovered that chitosan dissolved in solutions containing glycerol phosphate was soluble at near neutral pH and produce...

journal_title：Biomacromolecules

authors： Filion D,Lavertu M,Buschmann MD

更新日期：2007-10-01 00:00:00

abstract：:Two kinds of regioselectively substituted cellulose derivatives, i.e., 6-O-triphenylmethylcellulose (6TC) and 2,3-di-O-acetyl-6-O-triphenylmethylcellulose (2,3Ac6TC), were prepared via cellulose. In these samples, C-6 position hydroxyls in the anhydroglucose units (AGU) along the cellulose chain were selectively subst...

journal_title：Biomacromolecules

authors： Tsunashima Y,Hattori K,Kawanishi H,Horii F

更新日期：2001-10-01 00:00:00

abstract：:It was aim of the study to investigate the in vivo potential of a novel insulin-thiomer complex nanoparticulate delivery system. Insulin loaded nanoparticles were obtained by the formation of hydrogen bonds between poly(vinyl pyrrolidone) (PVP) and poly(acrylic acid)-cysteine (PAA-Cys) or poly(acrylic acid) (PAA), res...

journal_title：Biomacromolecules

authors： Deutel B,Greindl M,Thaurer M,Bernkop-Schnürch A

更新日期：2008-01-01 00:00:00

abstract：:Many dental restorative dental composites still utilize 2,2-bis[4-(2-hydroxy-3-methacryloyloxy propoxy) phenyl] propane (Bis-GMA) as base resin. The high viscosity of Bis-GMA necessitates dilution with dimethacrylate ethers of low viscosity such as triethylene glycol dimethacrylate (TEGDMA). However, increased amounts...

journal_title：Biomacromolecules

authors： Kim JW,Kim LU,Kim CK,Cho BH,Kim OY

更新日期：2006-01-01 00:00:00

abstract：:The synthesis and polymerization of six AB(3) tapered self-assembling methacrylate monomers (5a, 5b, 5c,5d, 17a, and 17b) based on first generation alkyl substituted benzyl ether monodendrons (i.e., minidendrons) containing oligooxyethylene units at their focal point and the polymerizable group on their periphery are ...

journal_title：Biomacromolecules

authors： Percec V,Bera TK

更新日期：2002-01-01 00:00:00

abstract：:The rational design of a polyplex gene carrier aims to balance maximal effectiveness of nucleic acid transfection into cells with minimal adverse effects. Depsipeptide blocks with an Mn ∼ 5 kDa exhibiting strong physical interactions were conjugated with PEI moieties (2.5 or 10 kDa) to di- and triblock copolymers. Upo...

journal_title：Biomacromolecules

authors： Wang W,Naolou T,Ma N,Deng Z,Xu X,Mansfeld U,Wischke C,Gossen M,Neffe AT,Lendlein A

更新日期：2017-11-13 00:00:00

abstract：:Microbial biofilms are ubiquitous in nature, and they pose a serious threat to public health. Staphylococcus epidermidis is the most common clinical isolate from healthcare- and medical device-related biofilm infections. No antibiotic currently on the market can eradicate pathogenic biofilms, which contain complex def...

journal_title：Biomacromolecules

authors： Lam AK,Wouters CL,Moen EL,Pusavat J,Rice CV

更新日期：2019-10-14 00:00:00

abstract：:One of the major drawbacks found in most bone tissue engineering approaches developed so far consists in the lack of strategies to promote vascularisation. Some studies have addressed different issues that may enhance vascularisation in tissue engineered constructs, most of them involving the use of growth factors (GF...

journal_title：Biomacromolecules

authors： Santo VE,Frias AM,Carida M,Cancedda R,Gomes ME,Mano JF,Reis RL

更新日期：2009-06-08 00:00:00

abstract：:A new method to form colloidally stable oligosaccharide-grafted synthetic polymer particles has been developed. The oligosaccharides, of weight-average degree of polymerization approximately 38, were obtained by enzymatic debranching of amylopectin. Through the use of a cerium(IV)-based redox initiation process, oligo...

journal_title：Biomacromolecules

authors： Mange S,Dever C,De Bruyn H,Gaborieau M,Castignolles P,Gilbert RG

更新日期：2007-06-01 00:00:00

abstract：:Bone fractures constitute a major cause of morbidity and mortality especially in the elderly. Complications associated with osteoporosis drugs and the age of the patient slow bone turnover and render such fractures difficult to heal. Increasing the speed of fracture repair by administration of a fracture-targeted bone...

journal_title：Biomacromolecules

authors： Low SA,Galliford CV,Yang J,Low PS,Kopeček J

更新日期：2015-10-12 00:00:00

abstract：:Chitosan-dendrimer hybrids having various functional groups such as carboxyl, ester, and poly(ethylene glycol) groups were prepared successfully using dendrimer acetal by reductive N-alkylation. The synthetic procedure could be accomplished by one-step reaction without organic solvent. The degree of substitution of de...

journal_title：Biomacromolecules

authors： Sashiwa H,Yajima H,Aiba S

更新日期：2003-09-01 00:00:00