Abstract：
:In this study, we demonstrate for the first time the fabrication of carboxylated chitosan nanocrystals (ChsNC) with high degree of deacetylation (DDA) at >80% and narrow size distribution. We also studied its application as a sustainable support material for metal-based catalysts. Carboxylated chitin nanocrystals (ChNCs) were initially prepared through partial cleavage of glycosidic bonds in chitin by ammonium persulfate, with concurrent oxidation of chitin C6 primary alcohols to produce carboxylate groups on the surface of the ChNCs. ChsNCs were subsequently prepared using an alkaline deacetylation procedure in the presence of NaBH4 to preserve the nanorod structure of the biomaterial. The resulting nanocrystals feature both carboxyl and amino functional groups. Transmission electron microscopy (TEM), X-ray diffraction (XRD), and Fourier-transform infrared (FTIR) spectroscopy were used to determine the morphology and composition of these carboxylated ChNCs and ChsNCs. Subsequently, we tested the ability of the as-made ChsNCs as a biomass-based catalyst support for Au nanoparticles (NPs) using the 4-nitrophenol reduction and the aldehyde-amine-alkyne (A3) coupling reactions to demonstrate its capabilities in regard to the ones of cellulose nanocrystals (CNCs). In particular, Au NPs over ChsNCs featured the highest turnover frequency (TOF) value for the 4-nitrophenol reduction reported for all Au-based catalysts supported on carbon-based systems. Spectroscopic and imaging techniques confirmed the importance of precisely controlling the redox state of Au as it is being deposited to afford a highly disperse active site on the bionano-support.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Jin T,Kurdyla D,Hrapovic S,Leung ACW,Régnier S,Liu Y,Moores A,Lam Edoi
10.1021/acs.biomac.0c00201subject
Has Abstractpub_date
2020-06-08 00:00:00pages
2236-2245issue
6eissn
1525-7797issn
1526-4602journal_volume
21pub_type
杂志文章abstract：:Bovine serum albumin (BSA) and poly(diallyldimethylammonium chloride) (PDADMAC) spontaneously form, over a range of ionic strength I and pH, dense fluids rich in both macroions. To study their nanostructure, these coacervates were prepared at low I and high pH (strong interaction) or at high I and lower pH (weaker int...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm049174p
更新日期：2005-05-01 00:00:00
abstract：:A combination of chemo-photodynamic therapy has been manifested as a promising strategy for efficient cancer treatment due to the enhanced therapeutic efficacy. Here, we designed doxorubicin (DOX)-loaded photoresponsive micelles (DPRMs) based on a combination of chlorin e6 (Ce6) and lipoic acid (LA) conjugated methoxy...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.8b00607
更新日期：2018-08-13 00:00:00
abstract：:High molecular weight trimethylene carbonate (TMC) and epsilon-caprolactone (CL) (co)polymers were synthesized. Melt pressed (co)polymer films were cross-linked by gamma irradiation (25 kGy or 50 kGy) in vacuum, yielding gel fractions of up to 70%. The effects of copolymer composition and irradiation dose on the cytot...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm8007988
更新日期：2008-11-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2014-04-14 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2017-12-11 00:00:00
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journal_title：Biomacromolecules
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更新日期：2012-12-10 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm400938n
更新日期：2013-11-11 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm0602076
更新日期：2006-09-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm500641f
更新日期：2014-08-11 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.0c01548
更新日期：2020-12-15 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.6b01891
更新日期：2017-03-13 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm701124p
更新日期：2008-06-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm1001476
更新日期：2010-10-11 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.9b01319
更新日期：2020-02-10 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm500156z
更新日期：2014-05-12 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm5006855
更新日期：2014-08-11 00:00:00
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journal_title：Biomacromolecules
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doi：10.1021/bm900398n
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journal_title：Biomacromolecules
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更新日期：2007-11-01 00:00:00
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journal_title：Biomacromolecules
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更新日期：2006-12-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2016-11-14 00:00:00
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更新日期：2002-01-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm100913z
更新日期：2011-01-10 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2009-12-14 00:00:00
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journal_title：Biomacromolecules
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更新日期：2006-07-01 00:00:00
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journal_title：Biomacromolecules
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.0c00169
更新日期：2020-06-08 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm100862k
更新日期：2010-12-13 00:00:00
