In depth study of a new highly efficient raw starch hydrolyzing α-amylase from Rhizomucor sp.

abstract：:We report a biodegradable fluorescent theranostic nanoprobe design strategy for simultaneous visualization and quantitative determination of antibacterial activity for the treatment of bacterial infections. Cationic-charged polycaprolactone (PCL) was tailor-made through ring-opening polymerization methodology, and it ...

journal_title：Biomacromolecules

authors： Ghosh R,Malhotra M,Madhuri Sathe RR,Jayakannan M

更新日期：2020-07-13 00:00:00

abstract：:Ozonolysis of methyl soyate (biodiesel) was conducted in the presence of methanol, dichloromethane (solvent), and triethylamine (catalyst) at -75 degrees C. Structural analysis, including FTIR, GC, and GC-MS, showed that the total amount of double bonds in the mixture was reduced by more than 90% after 2 h of ozonolys...

journal_title：Biomacromolecules

authors： Baber TM,Graiver D,Lira CT,Narayan R

更新日期：2005-05-01 00:00:00

abstract：:Regulating cell migration dynamics is of significance in tissue engineering and regenerative medicine. A 3D scaffold was created to provide various topographies based on a poly(ε-caprolactone) (PCL) self-induced nanohybrid shish-kebab structure, which consisted of aligned PCL nanofibers and spaced PCL crystal lamellae...

journal_title：Biomacromolecules

authors： Guo X,Wang X,Li X,Jiang YC,Han S,Ma L,Guo H,Wang Z,Li Q

更新日期：2020-03-09 00:00:00

abstract：:Photo-crosslinkable dendritic macromolecules are attractive materials for the preparation of cartilage tissue engineering scaffolds that may be optimized for in situ formation of hydrated, mechanically stable, and well-integrated hydrogel scaffolds supporting chondrocytes and chondrogenesis. We designed and synthesize...

journal_title：Biomacromolecules

authors： Söntjens SH,Nettles DL,Carnahan MA,Setton LA,Grinstaff MW

更新日期：2006-01-01 00:00:00

abstract：:Silkworm silk has excellent mechanical properties, biocompatibility, and promising applications in the biomedical sector. Silkworms spin silk at the beginning and end of each of their five instar stages, as well as spinning mature silk after the fifth instar. We evaluated the mechanical properties and structure of 10 ...

journal_title：Biomacromolecules

authors： Peng Z,Yang X,Liu C,Dong Z,Wang F,Wang X,Hu W,Zhang X,Zhao P,Xia Q

更新日期：2019-03-11 00:00:00

abstract：:Tannic acid (TA) can form stable complexes with proteins, attracting significant attention as protein delivery systems. However, its systemic application has been limited due to nonspecific interaction. Here, we report a simple technique to prepare systemically applicable protein delivery systems using sequential self...

journal_title：Biomacromolecules

authors： Honda Y,Nomoto T,Matsui M,Takemoto H,Kaihara Y,Miura Y,Nishiyama N

更新日期：2020-09-14 00:00:00

abstract：:A new synthetic route to beta-cyclodextrin-linked hyaluronic acid (HA-CD) was developed. This was based on the preparation of a HA derivative selectively modified with adipic dihydrazide (HA-ADH) and a beta-cyclodextrin derivative possessing an aldehyde function on the primary face, followed by their coupling by a red...

journal_title：Biomacromolecules

authors： Charlot A,Heyraud A,Guenot P,Rinaudo M,Auzély-Velty R

更新日期：2006-03-01 00:00:00

abstract：:New applications in regenerative biotechnology require the ability to understand and control protein-surface interactions on micrometer and submicrometer length scales. Evidence presented here shows that micropatterned amphiphilic comb polymer films exhibit a pretreatment-dependent behavior with respect to protein ads...

journal_title：Biomacromolecules

authors： Zhang Z,Ma H,Hausner DB,Chilkoti A,Beebe TP Jr

更新日期：2005-11-01 00:00:00

abstract：:Although the field of cancer immunotherapy is intensively investigated, there is still a need for generic strategies that allow easy, mild and efficient formulation of vaccine antigens. Here we report on a generic polymer-protein ligation strategy to formulate protein antigens into reversible polymeric conjugates for ...

journal_title：Biomacromolecules

authors： Lybaert L,Vanparijs N,Fierens K,Schuijs M,Nuhn L,Lambrecht BN,De Geest BG

更新日期：2016-03-14 00:00:00

abstract：:Polymerized high internal phase emulsions (polyHIPEs) have been utilized in the creation of injectable scaffolds that cure in situ to fill irregular bone defects and potentially improve tissue healing. Previously, thermally initiated scaffolds required hours to cure, which diminished the potential for clinical transla...

journal_title：Biomacromolecules

authors： Moglia RS,Whitely M,Dhavalikar P,Robinson J,Pearce H,Brooks M,Stuebben M,Cordner N,Cosgriff-Hernandez E

更新日期：2014-08-11 00:00:00

abstract：:The objective of this study was to design GE11 peptide (YHWYGYTPQNVI) linked micelles of poly(ethylene glycol)-block-poly(2-methyl-2-carboxyl-propylene carbonate-graft-gemcitabine-graft-dodecanol (PEG-b-PCC-g-GEM-g-DC) for enhanced stability and target specificity of gemcitabine (GEM) to EGFR-positive pancreatic cance...

journal_title：Biomacromolecules

authors： Mondal G,Kumar V,Shukla SK,Singh PK,Mahato RI

更新日期：2016-01-11 00:00:00

abstract：:We studied methoxy poly(ethylene glycol)-b-poly(ε-caprolactone)-b-poly(2-dimethylaminoethyl methacrylate) (mPEG-b-PCL-b-PDMAEMA) nanoparticles as the codelivery vector of hydrophobic drug and pDNA by employing dynamic light scattering (DLS), ζ potential, transmission electron microscopy (TEM), gel retardation assay, a...

journal_title：Biomacromolecules

authors： Yue X,Qiao Y,Qiao N,Guo S,Xing J,Deng L,Xu J,Dong A

更新日期：2010-09-13 00:00:00

abstract：:Major ampullate silk, also known as dragline silk, is one of the strongest biomaterials known. This silk is composed of two proteins, major ampullate spidroin 1 (MaSp1) and major ampullate spidroin 2 (MaSp2). Only partial cDNA sequences have been obtained for these proteins, and these sequences are toward the C-termin...

journal_title：Biomacromolecules

authors： Motriuk-Smith D,Smith A,Hayashi CY,Lewis RV

更新日期：2005-11-01 00:00:00

abstract：:Following the work carried out on guar gum in our first paper of a series, the "pressure cell" solubilization method was applied to two other less highly substituted galactomannans: locust bean gum (LBG) and tara gum. True molecular solution of the polymers was achieved using appropriate temperature, time, and pressur...

journal_title：Biomacromolecules

authors： Picout DR,Ross-Murphy SB,Jumel K,Harding SE

更新日期：2002-07-01 00:00:00

abstract：:In this work, 6-phosphogluconic trisodium salt (6-PG-Na+) is introduced as a new aqueous and nontoxic cross-linking agent to obtain ionic hydrogels. Here, it is shown the formation of hydrogels based on chitosan cross-linked with 6-PG-Na+. This formulation is obtained by ionic interaction of cationic groups of polymer...

journal_title：Biomacromolecules

authors： Martínez-Martínez M,Rodríguez-Berna G,Gonzalez-Alvarez I,Hernández MJ,Corma A,Bermejo M,Merino V,Gonzalez-Alvarez M

更新日期：2018-04-09 00:00:00

abstract：:The present study reports the folic acid (FA) functionalized insulin loaded stable liposomes with improved bioavailability following oral administration. Liposomes were stabilized by alternating coating of negatively charged poly(acrylic acid) (PAA) and positively charged poly(allyl amine) hydrochloride (PAH) over lip...

journal_title：Biomacromolecules

authors： Agrawal AK,Harde H,Thanki K,Jain S

更新日期：2014-01-13 00:00:00

abstract：:Block copolypeptides, which combine the self-assembly of block copolymers and the highly ordered 3D structures of proteins, are potential candidates for novel supramolecular structures and biotech applications, such as biosensors, tissue engineering, and selective drug delivery. The synthesis of model block copolypept...

journal_title：Biomacromolecules

authors： Aliferis T,Iatrou H,Hadjichristidis N

更新日期：2004-09-01 00:00:00

abstract：:Inflammation plays an important role in symptomatic intervertebral disc degeneration and is associated with the production of neurotrophins in sensitizing innervation into the disc. The use of high molecular weight (HMw) hyaluronic acid (HA) hydrogels offers a potential therapeutic biomaterial for nucleus pulposus (NP...

journal_title：Biomacromolecules

authors： Isa IL,Srivastava A,Tiernan D,Owens P,Rooney P,Dockery P,Pandit A

更新日期：2015-06-08 00:00:00

abstract：:Effects of poly(ethylene glycol) (PEG) conjugation on peptide interactions with lipid membranes and lipopolysaccharide (LPS) were investigated for KYE28 (KYEITTIHNLFRKLTHRLFRRNFGYTLR), an antimicrobial and anti-inflammatory peptide derived from human heparin cofactor II. In particular, effects of PEG length and locali...

journal_title：Biomacromolecules

authors： Singh S,Papareddy P,Mörgelin M,Schmidtchen A,Malmsten M

更新日期：2014-04-14 00:00:00

abstract：:Escherichia coli serogroup O5 comprises two different subgroups (O5ab and O5ac), which are indiscernible from the point of view of standard immunological serotyping. The structural similarities between the O-antigen polysaccharides (PSs) of these two strains are remarkable, with the only difference being the glycosidi...

journal_title：Biomacromolecules

authors： Sarkar A,Fontana C,Imberty A,Pérez S,Widmalm G

更新日期：2013-07-08 00:00:00

abstract：:Aggregation phenomena in aqueous solutions of purified human tracheobronchial mucin have been studied by rheological methods, steady-state fluorescence, quasielastic light scattering, and spin probe techniques. At temperatures below 30 degrees C and concentrations above 15 mg/mL and in the absence of chaotropic agents...

journal_title：Biomacromolecules

authors： Bromberg LE,Barr DP

更新日期：2000-10-01 00:00:00

abstract：:Electrospinning of cellulose nanocrystals (CNC)/poly(lactic acid) (PLA) emulsions has been demonstrated to be an effective dispersion and alignment method to control assembly of CNC into continuous composite ultrafine fibers. CNC-PLA nanocomposite random-fiber mats and aligned-fiber yarns were prepared by emulsion ele...

journal_title：Biomacromolecules

authors： Li Y,Ko FK,Hamad WY

更新日期：2013-11-11 00:00:00

abstract：:A recombinant silk-elastin-like protein copolymer SELP-47K containing tandemly repeated amino acid sequence blocks from silk, GAGAGS, and elastin, GVGVP, was fabricated into microdiameter fibers using a wet-spinning technique. Raman spectral analysis revealed the formation of antiparallel beta-sheet crystals of the si...

journal_title：Biomacromolecules

authors： Qiu W,Teng W,Cappello J,Wu X

更新日期：2009-03-09 00:00:00

abstract：:This study presents an efficient and systematic approach to synthesize bioapplicable porous hollow polymeric capsules (HPCs). The hydroxyl-functionalized nanoporous polymers with hollow capsular shapes could be generated via the moderate Friedel-Crafts reaction without using any hard or soft template. The numerous pri...

journal_title：Biomacromolecules

authors： Song W,Zhang Y,Yu DG,Tran CH,Wang M,Varyambath A,Kim J,Kim I

更新日期：2020-12-17 00:00:00

abstract：:PolyHIPEs show great promise as tissue engineering scaffolds due to the tremendous control of pore size and interconnectivity afforded by this technique. Highly porous, fully biodegradable scaffolds were prepared by polymerization of the continuous phase of high internal phase emulsions (HIPEs) containing the macromer...

journal_title：Biomacromolecules

authors： Christenson EM,Soofi W,Holm JL,Cameron NR,Mikos AG

更新日期：2007-12-01 00:00:00

abstract：:Bovine hemoglobin (Hb) was encapsulated inside polymer vesicles (polymersomes) to form polymersome encapsulated Hb (PEH) dispersions. PEH particles are 100% surface PEGylated with longer PEG chains and possess thicker hydrophobic membranes as compared to conventional liposomes. Polymersomes were self-assembled from po...

journal_title：Biomacromolecules

authors： Arifin DR,Palmer AF

更新日期：2005-07-01 00:00:00

abstract：:Polarization modulation infrared reflection absorption spectroscopy (PM-IRRAS) was applied to investigate the interaction of bovine serum albumin (BSA) and fibrinogen with a biomedical-grade 316LVM stainless steel surface, in terms of the adsorption thermodynamics and adsorption-induced secondary structure changes of ...

journal_title：Biomacromolecules

authors： Desroches MJ,Chaudhary N,Omanovic S

更新日期：2007-09-01 00:00:00

abstract：:Oligonucleotide-spider silk conjugates can be placed on silicon wafers by complementary DNA strands, which are coupled chemically to the surface. Such specific immobilization of spider silk proteins allows the nucleation and guided growth of β-sheet-rich nanofibrils in the presence of phosphate ions on the surface. Ad...

journal_title：Biomacromolecules

authors： Molina A,Scheibel T,Humenik M

更新日期：2019-01-14 00:00:00

abstract：:This study clarifies the contribution to overall osmotic kinetics of colloid osmotic pressure (Pi) and the interaction of synthetic colloids with the membrane. Solutions (6%) of dextran with weight average molecular weight (MW(w)) 68 800 (DEX 70), dextran with MW(w) 40 000 (DEX 40), hydroxyethyl starch with MW(w) 70 0...

journal_title：Biomacromolecules

authors： Tatara T,Tashiro C

更新日期：2005-05-01 00:00:00

abstract：:Developing green and nontoxic biomaterials, derived from renewable sources and processable through 3D bioprinting technologies, is an emerging challenge of sustainable tissue engineering. Here, pectin from citrus peels was cross-linked for the first time with (3-glycidyloxypropyl)trimethoxysilane (GPTMS) through a one...

journal_title：Biomacromolecules

authors： Lapomarda A,De Acutis A,Chiesa I,Fortunato GM,Montemurro F,De Maria C,Mattioli Belmonte M,Gottardi R,Vozzi G

更新日期：2020-02-10 00:00:00