Abstract:
:Silkworm silk has excellent mechanical properties, biocompatibility, and promising applications in the biomedical sector. Silkworms spin silk at the beginning and end of each of their five instar stages, as well as spinning mature silk after the fifth instar. We evaluated the mechanical properties and structure of 10 kinds of silk fibers from different stages. A tensile test showed that instar beginning silk, instar end silk, and mature silk possess distinct properties. Attenuated total reflectance Fourier-transform infrared spectroscopy and X-ray diffraction results showed that the excellent mechanical properties of instar end silk are attributed to higher β-sheet content and suitable crystallinity. Liquid chromatography-tandem mass spectrometry showed that P25 protein content in IV-E silk is 2.9× higher than that of cocoon silk. This study can offer guidelines for further biomimetic investigations into the design and manufacture of artificial silk protein fibers with novel function.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Peng Z,Yang X,Liu C,Dong Z,Wang F,Wang X,Hu W,Zhang X,Zhao P,Xia Qdoi
10.1021/acs.biomac.8b01576subject
Has Abstractpub_date
2019-03-11 00:00:00pages
1203-1216issue
3eissn
1525-7797issn
1526-4602journal_volume
20pub_type
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