Dimethyl Sulfoxide-Free Cryopreservation of Chondrocytes Based on Zwitterionic Molecule and Polymers.

abstract：:The effect of guluronate oligomers on the barrier properties of mucous matrices was investigated in terms of the mobility of nanoparticles in mucous matrices by fluorescence recovery after photobleaching (FRAP), cellular uptake of nanoparticles in mucus secreting cells (HT29-MTX), and mucin matrix architecture by scan...

journal_title：Biomacromolecules

authors： Nordgård CT,Nonstad U,Olderøy MØ,Espevik T,Draget KI

更新日期：2014-06-09 00:00:00

abstract：:The ability to adopt at least two different stable conformations is a common feature of proteins involved in many neurodegenerative diseases. The involved molecules undergo a conformational transition from native, mainly helical states to insoluble amyloid structures that have high β-sheet content. A detailed characte...

journal_title：Biomacromolecules

authors： Gerling UI,Brandenburg E,von Berlepsch H,Pagel K,Koksch B

更新日期：2011-08-08 00:00:00

abstract：:Fluorescence-tagged coniferyl alcohols, coniferyl alcohol γ-coupled by ethylenediamine spacers to dimethylaminocoumarin or nitrobenzofuran fluorophores, were tested as photoprobes to study the oxidase-mediated polymerization of monolignols. The fluorescent coniferyl alcohol derivatives readily underwent peroxidase-cat...

journal_title：Biomacromolecules

authors： Tobimatsu Y,Davidson CL,Grabber JH,Ralph J

更新日期：2011-05-09 00:00:00

abstract：:Sulfate cellulose nanocrystal (CNC) dispersions always present specific self-assembled cholesteric mesophases which is easily affected by the inherent properties of particle size, surface charge, and repulsion or affinity interaction, and external field force generated from ionic potential of added electrolytes, magne...

journal_title：Biomacromolecules

authors： Song W,Liu D,Prempeh N,Song R

更新日期：2017-10-09 00:00:00

abstract：:Coiled coils are a common structural motif in many natural proteins that can also be utilized in the design and preparation of drug delivery systems for the noncovalent connection of two macromolecules. In this work, two different pairs of peptides forming coiled coil hetero-oligomers were designed, synthesized, and c...

journal_title：Biomacromolecules

authors： Pechar M,Pola R,Laga R,Braunová A,Filippov SK,Bogomolova A,Bednárová L,Vaněk O,Ulbrich K

更新日期：2014-07-14 00:00:00

abstract：:The aggregation phenomena in aqueous solutions of hydrophobically modified (HM) chitosan, containing 4 mol % of n-dodecyl side chains, were studied by viscometry and fluorescence spectroscopy with pyrene as a probe. The results are compared with those for unmodified chitosan. Surprisingly, fluorescence data reveal the...

journal_title：Biomacromolecules

authors： Philippova OE,Volkov EV,Sitnikova NL,Khokhlov AR,Desbrieres J,Rinaudo M

更新日期：2001-07-01 00:00:00

abstract：:We study the self-assembly of genetically engineered protein-based triblock copolymers consisting of a central pH-responsive silk-like middle block (S(H)n, where S(H) is a silk-like octapeptide, (GA)3GH and n is the number of repeats) flanked by hydrophilic random coil outer blocks (C2). Our previous work has already ...

journal_title：Biomacromolecules

authors： Beun LH,Storm IM,Werten MW,de Wolf FA,Cohen Stuart MA,de Vries R

更新日期：2014-09-08 00:00:00

abstract：:The SEC-MALS-QELS (size-exclusion chromatography equipped with multiangle light scattering and quasi-elastic light scattering detectors) method using lithium chloride/N,N-dimethylacetamide (LiCl/DMAc) and LiCl/1,3-dimethyl-2-imidazolidinone (LiCl/DMI) as mobile phases was applied to cellulose and cellulose tricarbanil...

journal_title：Biomacromolecules

authors： Yanagisawa M,Isogai A

更新日期：2005-05-01 00:00:00

abstract：:A wood based yarn platform for capturing pharmaceutical molecules from water was developed. Cellulose fiber yarns were modified with cyclodextrins, and the capture of 17α-ethinyl estradiol (EE2), a synthetic estrogen hormone used as contraceptive, from water was tested. The yarns were prepared by spinning a deep eutec...

journal_title：Biomacromolecules

authors： Orelma H,Virtanen T,Spoljaric S,Lehmonen J,Seppälä J,Rojas OJ,Harlin A

更新日期：2018-02-12 00:00:00

abstract：:The development of large-scale suspension cell cultures using microcarriers has long been a focus of attention in the fields of pharmacy and biotechnology. Previously, we developed cell-detachable microcarriers based on temperature-responsive poly(N-isopropylacrylamide) (PIPAAm)-grafted beads, on which adhering cells ...

journal_title：Biomacromolecules

authors： Tamura A,Nishi M,Kobayashi J,Nagase K,Yajima H,Yamato M,Okano T

更新日期：2012-06-11 00:00:00

abstract：:Despite recent advances in tumor treatment through cancer immunotherapy, the efficacy of this approach remains to be improved. Looking forward to high rates of objective clinical response, cancer immunotherapy combined with chemotherapy has gained increasing attention recently. Here, we constructed liposomes with matr...

journal_title：Biomacromolecules

authors： Liu Y,Chen XG,Yang PP,Qiao ZY,Wang H

更新日期：2019-02-11 00:00:00

abstract：:Binding human serum albumin (HSA) of three polyoxometalates (POMs) with the Wells-Dawson structure, alpha(2)-[P2W17O61]10- (abbreviated as alpha(2)-P2W17) and two of its metal-substituted derivatives, alpha(2)-[NiP2W17O61]8- and alpha(2)-[CuP2W17O61]8- (alpha(2)-P2W17Ni and alpha(2)-P2W17Cu, respectively) was studied ...

journal_title：Biomacromolecules

authors： Zhang G,Keita B,Craescu CT,Miron S,de Oliveira P,Nadjo L

更新日期：2008-03-01 00:00:00

abstract：:Biocompatible photoresponsive materials are of interest for targeted drug delivery, tissue engineering, 2D and 3D protein patterning, and other biomedical applications. We prepared light degradable hydrogels using a natural alginate polysaccharide cross-linked with iron(III) cations. The "hard" iron(III) cations used ...

journal_title：Biomacromolecules

authors： Narayanan RP,Melman G,Letourneau NJ,Mendelson NL,Melman A

更新日期：2012-08-13 00:00:00

abstract：:Monoclonal antibodies (mAb) are a major focus of the pharmaceutical industry, and polyclonal immunoglobulin G (IgG) therapy is used to treat a wide variety of health conditions. As some individuals require mAb/IgG therapy their entire life, there is currently a great desire to formulate antibodies for bolus injection ...

journal_title：Biomacromolecules

authors： Gong Y,Soleymani Abyaneh H,Drossis N,Niederquell A,Kuentz M,Leroux JC,de Haan HW,Gauthier MA

更新日期：2019-09-09 00:00:00

abstract：:Molecular dynamics (MD) simulations have been applied to study the interactions between hydrophobic and hydrophilic faces of ordered cellulose chains and a single layer of graphene in explicit aqueous solvent. The hydrophobic cellulose face is predicted to form a stable complex with graphene. This interface remains so...

journal_title：Biomacromolecules

authors： Alqus R,Eichhorn SJ,Bryce RA

更新日期：2015-06-08 00:00:00

abstract：:In this study, generation 5 (G5) polyamidoamine (PAMAM) dendrimers with two different surface groups, G4.5-COOH and G5-OH, were investigated for their protective effects on pancreas injury in a caerulein-induced acute pancreatitis (AP) mouse model. Both dendrimers significantly decreased pathological changes in the pa...

journal_title：Biomacromolecules

authors： Tang Y,Han Y,Liu L,Shen W,Zhang H,Wang Y,Cui X,Wang Y,Liu G,Qi R

更新日期：2015-01-12 00:00:00

abstract：:Peak force infrared (PFIR) microscopy is a recently developed approach to acquire multiple chemical and physical material properties simultaneously and with nanometer resolution: topographical features, infrared (IR)-sensitive maps, adhesion, stiffness, and locally resolved IR spectra. This multifunctional mapping is ...

journal_title：Biomacromolecules

authors： Gusenbauer C,Jakob DS,Xu XG,Vezenov DV,Cabane É,Konnerth J

更新日期：2020-10-12 00:00:00

abstract：:In this paper we report on protein refolding by means of a liquid-liquid transfer technique using a calixarene. We have found that a calix[6]areneacetic acid derivative forms a supramolecular complex with urea-denatured cytochrome c at the oil-water interface, which enables quantitative transfer of the protein from an...

journal_title：Biomacromolecules

authors： Shimojo K,Oshima T,Naganawa H,Goto M

更新日期：2007-10-01 00:00:00

abstract：:A well-defined N-(2-hydroxypropyl)methacrylamide-s-N-(3-aminopropyl)methacrylamide (HPMA-s-APMA) copolymer, synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization, was utilized for the rational design of multiconjugates containing both a gene therapeutic, small interfering RNA (siRNA), ...

journal_title：Biomacromolecules

authors： York AW,Huang F,McCormick CL

更新日期：2010-02-08 00:00:00

abstract：:There is a distinct need for antimicrobial compounds that can act at surfaces without leaching into the environment. Such materials should be easy to synthesize, be easy to apply to surfaces, and display reasonable levels of antimicrobial and antifungal activity. Here we describe such a surface-active compound and dem...

journal_title：Biomacromolecules

authors： Ravikumar T,Murata H,Koepsel RR,Russell AJ

更新日期：2006-10-01 00:00:00

abstract：:Chitosan fibers showing narrow diameter distribution with a mean of 42 nm were produced by electrospinning and utilized for the sorption of Fe(III), Cu(II), Ag(I), and Cd(II) ions from aqueous solutions. The ion concentrations in the supernatant solutions were determined using inductively coupled plasma-mass spectrome...

journal_title：Biomacromolecules

authors： Horzum N,Boyaci E,Eroğlu AE,Shahwan T,Demir MM

更新日期：2010-12-13 00:00:00

abstract：:A multifunctional macromolecular thiol (TPVA) obtained by esterification of poly(vinyl alcohol) (PVA) with 3-mercaptopropionic acid was characterized by a combination of NMR, IR, transmission electron microscopy (TEM), and differential scanning calorimetry (DSC), and was used as a wheat gluten (WG) reactive modifier. ...

journal_title：Biomacromolecules

authors： Dicharry RM,Ye P,Saha G,Waxman E,Asandei AD,Parnas RS

更新日期：2006-10-01 00:00:00

abstract：:The rational design of a polyplex gene carrier aims to balance maximal effectiveness of nucleic acid transfection into cells with minimal adverse effects. Depsipeptide blocks with an Mn ∼ 5 kDa exhibiting strong physical interactions were conjugated with PEI moieties (2.5 or 10 kDa) to di- and triblock copolymers. Upo...

journal_title：Biomacromolecules

authors： Wang W,Naolou T,Ma N,Deng Z,Xu X,Mansfeld U,Wischke C,Gossen M,Neffe AT,Lendlein A

更新日期：2017-11-13 00:00:00

abstract：:Here we present time-resolved in situ transmission electron microscopy (TEM) observations and real-time manipulation of nematic ordered cellulose and ultradrawn polyethylene films. Drawn films of these two polymers exhibited a unique response to the low-dose electron beam. Electron beam damage was minimal based on ret...

journal_title：Biomacromolecules

authors： Brown RM Jr,Barnes Z,Sawatari C,Kondo T

更新日期：2007-01-01 00:00:00

abstract：:Infectious diseases remain one of the leading causes of death worldwide despite the tremendous effort devoted to the design and development of antimicrobial agents. However, the decrease in the effectiveness of some antibiotics is often associated with the development of drug resistance by pathogen. This leads to an u...

journal_title：Biomacromolecules

authors： Nguyen D,Nguyen TK,Rice SA,Boyer C

更新日期：2015-09-14 00:00:00

abstract：:Inflammation plays an important role in symptomatic intervertebral disc degeneration and is associated with the production of neurotrophins in sensitizing innervation into the disc. The use of high molecular weight (HMw) hyaluronic acid (HA) hydrogels offers a potential therapeutic biomaterial for nucleus pulposus (NP...

journal_title：Biomacromolecules

authors： Isa IL,Srivastava A,Tiernan D,Owens P,Rooney P,Dockery P,Pandit A

更新日期：2015-06-08 00:00:00

abstract：:We report an enzyme-based method for the in situ entrapment of cells within a biopolymeric hydrogel matrix. Specifically, we used a calcium-independent microbial transglutaminase that is known to cross-link proteins and observed that it catalyzes the formation of gels from a pre-gel solution containing 10% gelatin and...

journal_title：Biomacromolecules

authors： Chen T,Small DA,McDermott MK,Bentley WE,Payne GF

更新日期：2003-11-01 00:00:00

abstract：:Partially benzylamidated, amphipathic poly(gamma-glutamic acid) (BzPGA) was synthesized from poly(gamma-glutamic acid) (PGA) and benzylamine by direct amidation in dimethyl sulfoxide (DMSO). Benzylamine and PGA were heated in DMSO for 1 to 26 h at temperatures between 110 and 130 degrees C, producing derivatives of va...

journal_title：Biomacromolecules

authors： Novak L,Banyai I,Fleischer-Radu JE,Borbély J

更新日期：2007-05-01 00:00:00

abstract：:In this work, we have analyzed the structural, topographical, and surface dilatational characteristics of pure beta-lactoglobulin adsorbed films and the effect of the self-assembly of monoglycerides (monopalmitin or monoolein) in beta-lactoglobulin films at the air-water interface. Measurements were performed in a sin...

journal_title：Biomacromolecules

authors： Rodríguez Patino JM,Fernandez MC,Rodríguez Niño MR,Sanchez CC

更新日期：2006-09-01 00:00:00

abstract：:Cellulose and starch nanocrystals obtained from the acid hydrolysis of ramie fibers and waxy maize starch granules, respectively, were subjected to isocyanate-mediated reaction to graft polycaprolactone (PCL) chains with various molecular weights on their surface. Grafted nanoparticles were characterized by X-ray diff...

journal_title：Biomacromolecules

authors： Habibi Y,Dufresne A

更新日期：2008-07-01 00:00:00