Abstract:
:To continue expanding the use of Single Electron Transfer-Living Radical Polymerization (SET-LRP) in applications at the interface between macromolecular science, biomacromolecules, biology and medicine, it is essential to develop novel initiators that do not compromise the structural stability of synthesized polymers in biological environments. Here, we report that stable 2-bromopropionyl peptoid-type initiators such as 1,4-bis(2-bromopropionyl)piperazine and 4-(2-bromopropionyl)morpholine are an alternative that meets the standards reached by the well-known secondary and tertiary α-haloester-type initiators in terms of excellent control over molecular weight evolution and distribution as well as polymer chain ends. SET-LRP methodologies in organic, aqueous, and biphasic organic-aqueous media were evaluated for this purpose.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Lligadas G,Enayati M,Grama S,Smail R,Sherman SE,Percec Vdoi
10.1021/acs.biomac.7b00722subject
Has Abstractpub_date
2017-08-14 00:00:00pages
2610-2622issue
8eissn
1525-7797issn
1526-4602journal_volume
18pub_type
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