Long-circulating near-infrared fluorescence core-cross-linked polymeric micelles: synthesis, characterization, and dual nuclear/optical imaging.

abstract：:PEO-PPO-PEO triblock copolymers have opposing effects on lipid membrane integrity: they can behave either as membrane sealants or as membrane permeabilizers. To gain insights into their biomembrane activities, the fundamental interactions between a series of PEO-based polymers and phospholipid vesicles were investigat...

journal_title：Biomacromolecules

authors： Wang JY,Marks J,Lee KY

更新日期：2012-09-10 00:00:00

abstract：:A lamellar compound resulted from reaction of acrylic acid inside crystalline beta-chitin and the structure was investigated. Beta-chitin acts like a layered crystal, having stacked molecular sheets composed of parallel chains bound in one direction by intermolecular amide hydrogen bonding. Small guest molecules can b...

journal_title：Biomacromolecules

authors： Saito Y,Tomotake Y,Shida S

更新日期：2007-04-01 00:00:00

abstract：:Native cellulose consists of a set of parallel chains composed of glucose. Most of the time, these chains are highly ordered and form a structure that is known as a microfibril. On the other hand, highly crystalline forms of cellulose are more difficult to process and often are unpredictable in their behavior. If an o...

journal_title：Biomacromolecules

authors： Kondo T,Togawa E,Brown RM Jr

更新日期：2001-01-01 00:00:00

abstract：:This study shows the application of the electrospinning technique as a viable method for the encapsulation and stabilization of bifidobacterial strains. Poly(vinyl alcohol) (PVOH) was used as the encapsulating material because it is generally recognized as safe (GRAS), has a high oxygen barrier when dry, and is water ...

journal_title：Biomacromolecules

authors： López-Rubio A,Sanchez E,Sanz Y,Lagaron JM

更新日期：2009-10-12 00:00:00

abstract：:A new series of cationic, thermo-sensitive, and biodegradable poly(L-lactide)-poly(2-ethyl-2-oxazoline)-poly(L-lactide) (PLLA-PEOz-PLLA) triblock copolymers were synthesized by ring-opening polymerization. With increasing molecular weight and crystallinity of hydrophobic PLLA blocks, the critical micellization concent...

journal_title：Biomacromolecules

authors： Wang CH,Hsiue GH

更新日期：2003-11-01 00:00:00

abstract：:Polypeptide-based formulations that undergo liquid to hydrogel transitions upon change in temperature have become desirable targets since they can be mixed with cells or injected into tissues as liquids, and subsequently transform into rigid scaffolds or depots. Such materials have been challenging to prepare using sy...

journal_title：Biomacromolecules

authors： Zhang S,Alvarez DJ,Sofroniew MV,Deming TJ

更新日期：2015-04-13 00:00:00

abstract：:The thermal conductive properties, including the thermal diffusivity and resultant thermal conductivity, of nonwoven nanocellulose sheets were investigated by separately measuring the thermal diffusivity of the sheets in the in-plane and thickness directions with a periodic heating method. The cross-sectional area (or...

journal_title：Biomacromolecules

authors： Uetani K,Okada T,Oyama HT

更新日期：2015-07-13 00:00:00

abstract：:Imbalanced homeostasis and oligomerization of the amyloid-β (Aβ) peptide in the brain are hallmarks of Alzheimer's disease (AD). Microglia and macrophages play a critical role in the etiology of AD either by clearing Aβ from the brain or inducing inflammation. Recent evidence suggests that clearance of Aβ by microglia...

journal_title：Biomacromolecules

authors： Richman M,Perelman A,Gertler A,Rahimipour S

更新日期：2013-01-14 00:00:00

abstract：:Inorganic polyphosphates, linear polymers of orthophosphate, occur naturally throughout biology and have many industrial applications. Their biodegradable nature makes them attractive for a multitude of uses, and it would be important to understand how polyphosphates are turned over enzymatically. Studies of inorganic...

journal_title：Biomacromolecules

authors： Hebbard CF,Wang Y,Baker CJ,Morrissey JH

更新日期：2014-08-11 00:00:00

abstract：:Polymerized high internal phase emulsions (polyHIPEs) have been utilized in the creation of injectable scaffolds that cure in situ to fill irregular bone defects and potentially improve tissue healing. Previously, thermally initiated scaffolds required hours to cure, which diminished the potential for clinical transla...

journal_title：Biomacromolecules

authors： Moglia RS,Whitely M,Dhavalikar P,Robinson J,Pearce H,Brooks M,Stuebben M,Cordner N,Cosgriff-Hernandez E

更新日期：2014-08-11 00:00:00

abstract：:Agmatine-containing bioreducible polymer, poly(cystaminebis(acrylamide)-agmatine) (poly(CBA-AG)) was synthesized for gene delivery systems. It could form 200-300 nm sized and positively charged polyplexes with pDNA, which could release pDNA in reducing the environment due to the internal disulfide bonds cleavage. Poly...

journal_title：Biomacromolecules

authors： Choi JY,Ryu K,Lee GJ,Kim K,Kim TI

更新日期：2015-09-14 00:00:00

abstract：:Feasibility of using amphiphilic block copolymers composed of polylactide (PLA) and poly(ethylene oxide) (PEO) blocks for biomimetic surface modification of polylactide-based biomaterials for tissue engineering was investigated. PEO-b-PLA copolymers were deposited on the PLA surface from a solution in PEO-selective so...

journal_title：Biomacromolecules

authors： Tresohlavá E,Popelka S,Machová L,Rypácek F

更新日期：2010-01-11 00:00:00

abstract：:Many biological processes are regulated by reversible binding events, with these interactions between macromolecules representing the core of dynamic chemistry. As such, any attempt to gain a better understanding of such interactions, which would pave the way to the extrapolation of natural designs to create new advan...

journal_title：Biomacromolecules

authors： Fernández-Colino A,Arias FJ,Alonso M,Rodríguez-Cabello JC

更新日期：2015-10-12 00:00:00

abstract：:The SEC-MALS-QELS (size-exclusion chromatography equipped with multiangle light scattering and quasi-elastic light scattering detectors) method using lithium chloride/N,N-dimethylacetamide (LiCl/DMAc) and LiCl/1,3-dimethyl-2-imidazolidinone (LiCl/DMI) as mobile phases was applied to cellulose and cellulose tricarbanil...

journal_title：Biomacromolecules

authors： Yanagisawa M,Isogai A

更新日期：2005-05-01 00:00:00

abstract：:Hydrogel forming polysaccharides, such as the seaweed derived agarose, are well suited for wound dressing applications as they have excellent cell and soft tissue compatibility. For wound dressings, fibrous structure is desirable as the high surface area can favor adsorption of wound exudate and promote drug delivery....

journal_title：Biomacromolecules

authors： Forget A,Arya N,Randriantsilefisoa R,Miessmer F,Buck M,Ahmadi V,Jonas D,Blencowe A,Shastri VP

更新日期：2016-12-12 00:00:00

abstract：:A surface force balance was used to measure the normal and shear forces between two mica surfaces each bearing an adsorbed layer of porcine gastric mucin ("Orthana" mucin), genetically similar to human MUC6. This mucin is a highly purified, 546 kDa, weakly negative, polyampholytic molecule with a "dumbbell" structure....

journal_title：Biomacromolecules

authors： Harvey NM,Yakubov GE,Stokes JR,Klein J

更新日期：2011-04-11 00:00:00

abstract：:The fate of intravenously injected nanoparticles (NPs) is significantly affected by nano-protein interaction and corona formation. However, such an interaction between NPs and digestive enzymes occurring in the gastrointestinal tract (GIT) and its impacts on epithelial cell uptake are little known. We synthesized the ...

journal_title：Biomacromolecules

authors： Peng Q,Liu J,Zhang T,Zhang TX,Zhang CL,Mu H

更新日期：2019-04-08 00:00:00

abstract：:Evidence is presented that the polysaccharide rhamnogalacturonan I (RGI) can be biosynthesized in remarkably organized branched configurations and surprisingly long versions and can self-assemble into a plethora of structures. AFM imaging has been applied to study the outer mucilage obtained from wild-type (WT) and mu...

journal_title：Biomacromolecules

authors： Williams MAK,Cornuault V,Irani AH,Symonds VV,Malmström J,An Y,Sims IM,Carnachan SM,Sallé C,North HM

更新日期：2020-04-13 00:00:00

abstract：:Core-shell structured nanoparticles (NPs) render the simultaneous coloading capacity of both hydrophobic and hydrophilic drugs and may eventually enhance therapeutic efficacy. In this study, we employed a facile squalenoylation technology to synthesize a new amphiphilic starch derivative from partially oxidized starch...

journal_title：Biomacromolecules

authors： Phan VHG,Trang Duong HT,Tran PT,Thambi T,Ho DK,Murgia X

更新日期：2020-12-21 00:00:00

abstract：:Hydrophobic methacrylic monomers were polymerized in aqueous media using methylated (1.8)-beta-cyclodextrin (MeCD) additives. Hydrophobic monomers tert-butyl methacrylate (tBuMA), cyclohexyl methacrylate (CMA), and 2-ethylhexyl methacrylate (2EHMA) were each dissolved in chloroform with MeCD. Chloroform was then evapo...

journal_title：Biomacromolecules

authors： Madison PH,Long TE

更新日期：2000-01-01 00:00:00

abstract：:Inorganic polyphosphate (polyP) released by human platelets has recently been shown to activate blood clotting and identified as a potential target for the development of novel antithrombotics. Recent studies have shown that polymers with cationic binding groups (CBGs) inhibit polyP and attenuate thrombosis. However, ...

journal_title：Biomacromolecules

authors： Mafi A,Abbina S,Kalathottukaren MT,Morrissey JH,Haynes C,Kizhakkedathu JN,Pfaendtner J,Chou KC

更新日期：2018-04-09 00:00:00

abstract：:There is a distinct need for antimicrobial compounds that can act at surfaces without leaching into the environment. Such materials should be easy to synthesize, be easy to apply to surfaces, and display reasonable levels of antimicrobial and antifungal activity. Here we describe such a surface-active compound and dem...

journal_title：Biomacromolecules

authors： Ravikumar T,Murata H,Koepsel RR,Russell AJ

更新日期：2006-10-01 00:00:00

abstract：:Degradable polymers with specifically designed functionality have wide applications in biomedical fields. We reported herein the synthesis and characterization of a water-soluble and fast-degradable polycarbonate, functionalized with tertiary amine groups in the backbone. A novel cyclic carbonate monomer, namely, 6,14...

journal_title：Biomacromolecules

authors： Wang HF,Su W,Zhang C,Luo XH,Feng J

更新日期：2010-10-11 00:00:00

abstract：:The objective of these investigations was to test the hypothesis that a rapid cytoplasmic release profile from nanoparticles would potentiate the anticancer activity of cisplatin. Cisplatin-loaded nanoparticles with pH-responsive poly[2-(N,N-diethylamino)ethyl methacrylate] (PDEA) cores were synthesized from PDEA-bloc...

journal_title：Biomacromolecules

authors： Xu P,Van Kirk EA,Murdoch WJ,Zhan Y,Isaak DD,Radosz M,Shen Y

更新日期：2006-03-01 00:00:00

abstract：:Softwood and hardwood celluloses were oxidized by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation. The TEMPO-oxidized cellulose fibers were converted to transparent dispersions in water, which consisted of individual nanofibers 3-4 nm in width. Films were then prepared from the TEMPO-oxidized c...

journal_title：Biomacromolecules

authors： Fukuzumi H,Saito T,Iwata T,Kumamoto Y,Isogai A

更新日期：2009-01-12 00:00:00

abstract：:The water-soluble arabinoxylans from wheat flour (high, medium, and low viscosity samples) and rye flour (high viscosity sample) were characterized by (1)H NMR spectroscopy and HPSEC with refractive index, light scattering, and viscometric detectors. These cereal arabinoxylans have recently been used as model arabinox...

journal_title：Biomacromolecules

authors： Pitkänen L,Virkki L,Tenkanen M,Tuomainen P

更新日期：2009-07-13 00:00:00

abstract：:Weissella confusa VTT E-90392 is an efficient producer of a dextran that is mainly composed of α-(1→6)-linked D-glucosyl units and very few α-(1→3) branch linkages. A mixture of the Chaetomium erraticum endodextranase and the Aspergillus niger α-glucosidase was used to hydrolyze W. confusa dextran to glucose and a set...

journal_title：Biomacromolecules

authors： Maina NH,Virkki L,Pynnönen H,Maaheimo H,Tenkanen M

更新日期：2011-02-14 00:00:00

abstract：:Silk fibroin (SF) protein, produced by silkworm Bombyx mori, is a promising biomaterial, while sophorolipid (SL) is an amphiphilic functional biosurfactant synthesized by nonpathogenic yeast Candida bombicola. SL is a mixture of two forms, acidic (ASL) and lactonic (LSL), which when added to SF results in accelerated ...

journal_title：Biomacromolecules

authors： Dubey P,Kumar S,Aswal VK,Ravindranathan S,Rajamohanan PR,Prabhune A,Nisal A

更新日期：2016-10-10 00:00:00

abstract：:Eosinophil cationic protein (ECP) is an antimicrobial protein belonging to the superfamily of RNase A. ECP exhibits a broad spectrum of action against bacteria and, at higher concentrations, displays cytotoxic activity to eukaryotic cells. Recently, a powerful aggregation activity for lipid vesicles and for the gram-n...

journal_title：Biomacromolecules

authors： Torrent M,Odorizzi F,Nogués MV,Boix E

更新日期：2010-08-09 00:00:00

abstract：:A hyperbranched conjugated polyelectrolyte (HCPE) with a core-shell structure is designed and synthesized via alkyne polycyclotrimerization and click chemistry. The HCPE has an emission maximum at 565 nm with a quantum yield of 12% and a large Stokes shift of 143 nm in water. By virtue of its poly(ethylene glycol) she...

journal_title：Biomacromolecules

authors： Pu KY,Shi J,Cai L,Li K,Liu B

更新日期：2011-08-08 00:00:00