Encapsulation of living bifidobacteria in ultrathin PVOH electrospun fibers.

abstract：:Oligosaccharides of hydroxypropylmethyl cellulose, hydroxypropyl cellulose, and methyl cellulose were investigated by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). The cellulose ether oligosaccharides were produced either by enzymatic depolymerization utilizing the purified family 5 endoglu...

journal_title：Biomacromolecules

authors： Momcilovic D,Schagerlöf H,Wittgren B,Wahlund KG,Brinkmalm G

更新日期：2005-09-01 00:00:00

abstract：:As with many other biosourced colloids, chitin nanocrystals (ChNCs) can form liquid crystalline phases with chiral nematic ordering. In this work, we demonstrate that it is possible to finely tune the liquid crystalline behavior of aqueous ChNC suspensions finely. Such control was made possible by carefully studying h...

journal_title：Biomacromolecules

authors： Narkevicius A,Steiner LM,Parker RM,Ogawa Y,Frka-Petesic B,Vignolini S

更新日期：2019-07-08 00:00:00

abstract：:The adsorption of human immunoglobulin G (hIgG) and bovine serum albumin (BSA) on cellulose supports were investigated. The dynamics and extent of related adsorption processes were monitored by surface plasmon resonance (SPR) and quartz crystal microbalance with dissipation monitoring (QCM-D). Amine groups were instal...

journal_title：Biomacromolecules

authors： Orelma H,Filpponen I,Johansson LS,Laine J,Rojas OJ

更新日期：2011-12-12 00:00:00

abstract：:In this work, cell-responsive polysaccharide hydrogels were prepared by a simple procedure based on the sequential bioconjugation and cross-linking of the polysaccharide backbone with bioactive peptides and poly(ethylene glycol)-bis(thiol) (PEG-(SH)2), respectively. Using thiol-ene reactions, we successfully functiona...

journal_title：Biomacromolecules

authors： Jing J,Fournier A,Szarpak-Jankowska A,Block MR,Auzély-Velty R

更新日期：2015-03-09 00:00:00

abstract：:The time-dependent diffusion and mechanical properties of gelatin in solution, in the gel state, and during the sol/gel transition were determined using fluorescence recovery after photobleaching (FRAP) and rheology. The parameters in the experimental design were 2% w/w and 5% w/w gelatin concentration; 15, 20, and 25...

journal_title：Biomacromolecules

authors： Hagman J,Lorén N,Hermansson AM

更新日期：2010-12-13 00:00:00

abstract：:The viscous mucus coating that adheres to the epithelial surfaces of mammalian organs provides protection for the underlying tissues and is an efficient barrier to drug delivery. Pulsed-gradient spin-echo NMR and small-angle neutron scattering have been used to study the aqueous solution interaction of various model p...

journal_title：Biomacromolecules

authors： Griffiths PC,Occhipinti P,Morris C,Heenan RK,King SM,Gumbleton M

更新日期：2010-01-11 00:00:00

abstract：:Weissella confusa VTT E-90392 is an efficient producer of a dextran that is mainly composed of α-(1→6)-linked D-glucosyl units and very few α-(1→3) branch linkages. A mixture of the Chaetomium erraticum endodextranase and the Aspergillus niger α-glucosidase was used to hydrolyze W. confusa dextran to glucose and a set...

journal_title：Biomacromolecules

authors： Maina NH,Virkki L,Pynnönen H,Maaheimo H,Tenkanen M

更新日期：2011-02-14 00:00:00

abstract：:Controlling self-assembly is critical to the advancement of nanotechnology. A rugged or crenated assembly energy surface can redirect assembly off path. By using a defined starting point and an energy surface made rough by a strong association energy, we can impose entirely new assembly paths and products. Normally, t...

journal_title：Biomacromolecules

authors： Burns K,Mukherjee S,Keef T,Johnson JM,Zlotnick A

更新日期：2010-02-08 00:00:00

abstract：:The carboxyl-terminal domain (CTD, residues 146-231) of the HIV-1 capsid (CA) protein plays an important role in the CA-CA dimerization and viral assembly of the human immunodeficiency virus type 1. Disrupting the native conformation of the CA is essential for blocking viral capsid formation and viral replication. Thu...

journal_title：Biomacromolecules

authors： Yu X,Wang Q,Yang JC,Buch I,Tsai CJ,Ma B,Cheng SZ,Nussinov R,Zheng J

更新日期：2009-02-09 00:00:00

abstract：:Targeted delivery of antigens to immune cells using micro/nanocarriers may serve as a therapeutic application for vaccination. However, synthetic carriers have potential drawbacks including cytotoxicity, low encapsulation efficiency of antigen, and lack of a morphological design, which limit the translation of the del...

journal_title：Biomacromolecules

authors： Nishiguchi A,Shima F,Singh S,Akashi M,Moeller M

更新日期：2020-06-08 00:00:00

abstract：:alpha-Conotoxins possess a conserved four-cysteine framework and disulfide linkages (C(1)(-)(3), C(2)(-)(4)) that fold toward the globular conformation with absolute fidelity. Despite the presence of a similar conserved set of cysteine framework, chi/lambda-conotoxins adopt an alternate disulfide-pairing (C(1)(-)(4), ...

journal_title：Biomacromolecules

authors： Kang TS,Jois SD,Kini RM

更新日期：2006-08-01 00:00:00

abstract：:Silk-elastin-like proteins (SELPs) have enormous potential for use as customizable biomaterials in numerous biomedical and materials applications, yet success in harnessing this potential has been limited by the lack of a commercially viable industrially relevant production process. We have developed a scalable fed-ba...

journal_title：Biomacromolecules

authors： Collins T,Barroca M,Branca F,Padrão J,Machado R,Casal M

更新日期：2014-07-14 00:00:00

abstract：:The self-assembly properties of fibrous proteins such as collagen are frequently used to form three-dimensional scaffolds. In this study we investigated the effect of nonuniform alternating and static electric-fields on the self-assembly properties of a dilute solution of vimentin. In the presence of both types of fie...

journal_title：Biomacromolecules

authors： Colbourne TR,Hill IG,Kreplak L

更新日期：2009-07-13 00:00:00

abstract：:Safe delivery systems that can not only encapsulate hydrophobic drug molecules, but also release them in response to specific triggers are important in several therapeutic and biomedical applications. In this paper, we have designed a nanogel based on molecules that are generally recognized as safe (GRAS). We have sho...

journal_title：Biomacromolecules

authors： Prasad P,Molla MR,Cui W,Canakci M,Osborne B,Mager J,Thayumanavan S

更新日期：2015-11-09 00:00:00

abstract：:A novel pH-sensitive amphiphilic copolymer brush poly(methyl methacrylate-co-methacrylic acid)-b-poly(poly(ethylene glycol) methyl ether monomethacrylate) [P(MMA-co-MAA)-b-PPEGMA] was defined and synthesized by atom transfer radical polymerization (ATRP) technique. The molecular structures and characteristics of this ...

journal_title：Biomacromolecules

authors： Yang YQ,Zheng LS,Guo XD,Qian Y,Zhang LJ

更新日期：2011-01-10 00:00:00

abstract：:Ruthenium(II) tris(bipyridine)-centered poly(ethylenimine) (Ru PEI) was synthesized via acid hydrolysis of Ru tris(bipyridine)-centered poly(2-ethyl-2-oxazoline) (Ru PEOX), and the luminescence, DNA entrapment, and transfection efficiencies were evaluated. Emission maxima for Ru PEI samples are red-shifted compared to...

journal_title：Biomacromolecules

authors： Fiore GL,Edwards JM,Payne SJ,Klinkenberg JL,Gioeli DG,Demas JN,Fraser CL

更新日期：2007-09-01 00:00:00

abstract：:Minimally invasive implants and/or scaffolds integrated with multiple functionalities are of interest in the clinical settings. In this paper, chitosan (CTS) functionalized poly(lactic-co-glycolic acid) (PLGA) microspheres containing a model payload, lysozyme (Lyz), were prepared by a water-in-oil-in-water emulsion me...

journal_title：Biomacromolecules

authors： Bao M,Zhou Q,Dong W,Lou X,Zhang Y

更新日期：2013-06-10 00:00:00

abstract：:The hierarchical self-assembly of cellulose nanocrystals (CNCs) is an important phenomenon occurring naturally in plant cell walls. Utilization of this assembly for advanced applications requires a fundamental theoretical understanding of interactions between the CNCs, which is still incomplete. Hence, in this work, w...

journal_title：Biomacromolecules

authors： Garg M,Linares M,Zozoulenko I

更新日期：2020-08-10 00:00:00

abstract：:Multicomponent poly(ethylene glycol) (PEG) brushes (i.e., ≥ 2 adjacent PEG brushes) can be used to engineer culture substrates with microscale, nonfouling regions decorated with covalently immobilized ligands that mediate biospecific interactions. However, synthesizing such brushes with orthogonal immobilization chemi...

journal_title：Biomacromolecules

authors： Sha J,Lippmann ES,McNulty J,Ma Y,Ashton RS

更新日期：2013-09-09 00:00:00

abstract：:PLGA nanoparticles are among the most studied polymer nanoformulations for several drugs against different kinds of malignant diseases, thanks to their in vivo stability and tumor localization exploiting the well-documented "enhanced permeation and retention" (EPR) effect. In this paper, we have developed uniform curc...

journal_title：Biomacromolecules

authors： Verderio P,Bonetti P,Colombo M,Pandolfi L,Prosperi D

更新日期：2013-03-11 00:00:00

abstract：:Peptide self-assembly is a facile route to the development of bioorganic hybrid materials that have sophisticated nanostructures toward diverse applications. Here, we report the synthesis of self-assembled peptide (Fmoc-diphenylalanine, Fmoc-FF)/graphitic carbon nitride (g-C3N4) hydrogels for light harvesting and biom...

journal_title：Biomacromolecules

authors： Ko JW,Choi WS,Kim J,Kuk SK,Lee SH,Park CB

更新日期：2017-11-13 00:00:00

abstract：:Fluorescence and circular dichroism spectroscopy were used to monitor the conformational transition of regenerated Bombyx mori silk fibroin (RSF) in aqueous solutions under different conditions. According to the analysis of fluorescence spectra using anilinonaphthalene-8-sulfonic acid magnesium salt (ANS) as an extern...

journal_title：Biomacromolecules

authors： Yang Y,Shao Z,Chen X,Zhou P

更新日期：2004-05-01 00:00:00

abstract：:Oxidative coupling of phenol-containing precursor poly(amino acid)s, poly(alpha-glutamine), poly(alpha/beta-asparagine), and poly(gamma-glutamine) derivatives, has been examined to produce a new class of soluble poly(amino acid)s. Under appropriate reaction conditions, the Fe-salen and HRP catalysts efficiently induce...

journal_title：Biomacromolecules

authors： Fukuoka T,Uyama H,Kobayashi S

更新日期：2004-05-01 00:00:00

abstract：:An enzymatically cross-linked polyethylene glycol (PEG)-based hydrogel was engineered to promote and align nerve cells in a three-dimensional manner. To render the injectable, otherwise bioinert, PEG-based material supportive for cell growth, its mechanical and biochemical properties were optimized. A recombinant fibr...

journal_title：Biomacromolecules

authors： Licht C,Rose JC,Anarkoli AO,Blondel D,Roccio M,Haraszti T,Gehlen DB,Hubbell JA,Lutolf MP,De Laporte L

更新日期：2019-11-11 00:00:00

abstract：:Although the field of cancer immunotherapy is intensively investigated, there is still a need for generic strategies that allow easy, mild and efficient formulation of vaccine antigens. Here we report on a generic polymer-protein ligation strategy to formulate protein antigens into reversible polymeric conjugates for ...

journal_title：Biomacromolecules

authors： Lybaert L,Vanparijs N,Fierens K,Schuijs M,Nuhn L,Lambrecht BN,De Geest BG

更新日期：2016-03-14 00:00:00

abstract：:Polycaprolactone (PCL) was reported a long time ago; however, its biomedical applications has not been extensively investigated in comparison with poly(lactide- co-glycolide) (PLGA) due to its too slow degradation profile. Here, we are reporting an oxalate-connected oligocaprolactone multiblock copolymer (PCL-OX) as a...

journal_title：Biomacromolecules

authors： Chang SH,Lee HJ,Park S,Kim Y,Jeong B

更新日期：2018-06-11 00:00:00

abstract：:Protein-based polymers are increasingly being used in biomaterial applications because of their ease of customization and potential monodispersity. These advantages make protein polymers excellent candidates for bioanalytical applications. Here we describe improved methods for producing drag-tags for free-solution con...

journal_title：Biomacromolecules

authors： Lin JS,Albrecht JC,Meagher RJ,Wang X,Barron AE

更新日期：2011-06-13 00:00:00

abstract：:Injectable gels that support load are desirable for restoring the mechanical properties of degenerated load-bearing tissue. As these gels become increasingly sophisticated, the need to remotely image them and monitor their swelling increases. However, imaging such gels and monitoring their swelling using noninvasive m...

journal_title：Biomacromolecules

authors： Shanks HR,Milani AH,Lu D,Saunders BR,Carney L,Adlam DJ,Hoyland JA,Blount C,Dickinson M

更新日期：2019-07-08 00:00:00

abstract：:As a programmable biopolymer, DNA has shown great potential in the fabrication and construction of nanometer-scale assemblies and devices. In this report, we described a strategy for efficient manipulation of gold nanoparticle-bound DNA using restriction endonuclease. The digestion efficiency of this restriction enzym...

journal_title：Biomacromolecules

authors： Qin WJ,Yung LY

更新日期：2006-11-01 00:00:00

abstract：:Development of versatile nanoscale platforms for cancer diagnosis and therapy is of great importance for applications in translational medicine. In this work, we present the use of γ-polyglutamic acid (γ-PGA) nanogels (NGs) to load polypyrrole (PPy) for thermal/photoacoustic (PA) imaging and radiotherapy (RT)-sensitiz...

journal_title：Biomacromolecules

authors： Zhou Y,Hu Y,Sun W,Lu S,Cai C,Peng C,Yu J,Popovtzer R,Shen M,Shi X

更新日期：2018-06-11 00:00:00