Improved chemical analysis of cellulose ethers using dialkylamine derivatization and mass spectrometry.

abstract：:Benefiting from their inherent localized and controlled release properties, hydrogels are ideal delivery systems for therapeutic drugs or nanoparticles. In particular, applications of hydrogels for the delivery and release of photoresponsive drugs or nanoparticles are receiving increasing attention. However, the effec...

journal_title：Biomacromolecules

authors： Xia LY,Zhang X,Cao M,Chen Z,Wu FG

更新日期：2017-10-09 00:00:00

abstract：:The barrier functions of the stratum corneum and the epidermal layers present a tremendous challenge in achieving effective transdermal delivery of drug molecules. Although a few reports have shown that poly(amidoamine) (PAMAM) dendrimers are effective skin-penetration enhancers, little is known regarding the fundamen...

journal_title：Biomacromolecules

authors： Yang Y,Sunoqrot S,Stowell C,Ji J,Lee CW,Kim JW,Khan SA,Hong S

更新日期：2012-07-09 00:00:00

abstract：:Although composed simply of glucose polymers, the starch granule is a complex, semicrystalline structure. Much of this complexity arises from the fact that the two primary enzymes of synthesis-starch synthase and starch-branching enzyme-exist as multiple isoforms. Each form has distinct properties and plays a unique r...

journal_title：Biomacromolecules

authors： Smith AM

更新日期：2001-07-01 00:00:00

abstract：:Oscillatory shear rheometry has been used to study the gelation of beta-lactoglobulin at ambient in 50% v/v trifluoroethanol (TFE)/pH 7 aqueous buffer and in 50% v/v ethanol (EtOH)/water at pH 2. In contrast to what was found on heating aqueous solutions at pH 2 (Part 2 of this series), a more expected "chemical gelat...

journal_title：Biomacromolecules

authors： Gosal WS,Clark AH,Ross-Murphy SB

更新日期：2004-11-01 00:00:00

abstract：:Softwood and hardwood celluloses were oxidized by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation. The TEMPO-oxidized cellulose fibers were converted to transparent dispersions in water, which consisted of individual nanofibers 3-4 nm in width. Films were then prepared from the TEMPO-oxidized c...

journal_title：Biomacromolecules

authors： Fukuzumi H,Saito T,Iwata T,Kumamoto Y,Isogai A

更新日期：2009-01-12 00:00:00

abstract：:Collagen fibrils were obtained in vitro by aggregation from acid-soluble type I collagen at different initial concentrations and with the addition of decorin core or intact decorin. All specimens were observed by scanning electron microscopy and atomic force microscopy. In line with the findings of other authors, lack...

journal_title：Biomacromolecules

authors： Raspanti M,Viola M,Sonaggere M,Tira ME,Tenni R

更新日期：2007-07-01 00:00:00

abstract：:Chitosan hydrogel microspheres were obtained by cross-linking chitosan in its inverse emulsion using genipin as cross-linker. The genipin-cross-linked chitosan microspheres (ChGp) swell significantly in water at pH values below 6.5 and shrink to a smaller extent at pH values above 6.5. ChGp microspheres bind heparin i...

journal_title：Biomacromolecules

authors： Kamiński K,Zazakowny K,Szczubiałka K,Nowakowska M

更新日期：2008-11-01 00:00:00

abstract：:Oxidative coupling of phenol-containing precursor poly(amino acid)s, poly(alpha-glutamine), poly(alpha/beta-asparagine), and poly(gamma-glutamine) derivatives, has been examined to produce a new class of soluble poly(amino acid)s. Under appropriate reaction conditions, the Fe-salen and HRP catalysts efficiently induce...

journal_title：Biomacromolecules

authors： Fukuoka T,Uyama H,Kobayashi S

更新日期：2004-05-01 00:00:00

abstract：:G-quadruplex is a type of DNA secondary structure formed by specific guanine-rich sequences. Because of their enrichment in functional genomic regions and their biological significance, G-quadruplexes are recognized as significant drug targets for cancer and other diseases. Here, we tested the precipitation efficiency...

journal_title：Biomacromolecules

authors： Lin J,Yan YY,Ou TM,Tan JH,Huang SL,Li D,Huang ZS,Gu LQ

更新日期：2010-12-13 00:00:00

abstract：:The massive use of antibiotics in healthcare and agriculture has led to their artificial accumulation in natural habitats, which risks the structure and function of the microbial communities in ecosystems, threatens food and water security, and accelerates the development of resistome. Ideally, antibiotics should rema...

journal_title：Biomacromolecules

authors： Zheng W,Anzaldua M,Arora A,Jiang Y,McIntyre K,Doerfert M,Winter T,Mishra A,Ma H,Liang H

更新日期：2020-06-08 00:00:00

abstract：:A new synthetic route to beta-cyclodextrin-linked hyaluronic acid (HA-CD) was developed. This was based on the preparation of a HA derivative selectively modified with adipic dihydrazide (HA-ADH) and a beta-cyclodextrin derivative possessing an aldehyde function on the primary face, followed by their coupling by a red...

journal_title：Biomacromolecules

authors： Charlot A,Heyraud A,Guenot P,Rinaudo M,Auzély-Velty R

更新日期：2006-03-01 00:00:00

abstract：:The aim of this paper is to define optimal conditions for the extraction of chitin from shrimp shells. The kinetics of both demineralization and deproteinization with, in the latter case, the role of temperature are studied. The characterization of the residual calcium and protein contents, the molecular weights, and ...

journal_title：Biomacromolecules

authors： Percot A,Viton C,Domard A

更新日期：2003-01-01 00:00:00

abstract：:Mixed protein-based hydrogels have been prepared by blending gelatin (G) with amorphous Bombyx mori silk fibroin (SF) and promoting beta-crystallization of SF via subsequent exposure to methanol or methanol/water solutions. The introduction of beta crystals in SF serves to stabilize the hydrogel network and extend the...

journal_title：Biomacromolecules

authors： Gil ES,Frankowski DJ,Spontak RJ,Hudson SM

更新日期：2005-11-01 00:00:00

abstract：:Peptide RATEA16 spontaneously self-assembled into higher-order nanofiber hydrogels with extremely high water content (>99.5% (wt/vol)) under physiological condition. The hydrogels could undergo pH-reversible transitions from viscous solution to elastic hydrogel and to precipitate. The supramolecular self-assembly and ...

journal_title：Biomacromolecules

authors： Zhao Y,Yokoi H,Tanaka M,Kinoshita T,Tan T

更新日期：2008-06-01 00:00:00

abstract：:Aberrant expression of histone deacetylases (HDACs) is related to various types of cancer and is associated with increased proliferation of tumor cells. Hence, the detection of HDAC activities is of great significance for medical sciences as well as biological diagnostics. Herein, we report a hyperbranched polyester-b...

journal_title：Biomacromolecules

authors： Yu C,Wu Y,Zeng F,Li X,Shi J,Wu S

更新日期：2013-12-09 00:00:00

abstract：:Recent research indicates that the progression of Parkinson's disease can start from neurons of the enteric nervous system, which are in close contact with the gastrointestinal epithelium: α-synuclein molecules can be transferred from these epithelial cells in a prion-like fashion to enteric neurons. Thin mucus layers...

journal_title：Biomacromolecules

authors： Marczynski M,Rickert CA,Semerdzhiev SA,van Dijk WR,Segers-Nolten IMJ,Claessens MMAE,Lieleg O

更新日期：2019-12-09 00:00:00

abstract：:The need for polymers for high-end applications, coupled with the desire to mimic nature's macromolecular machinery fuels the development of innovative synthetic strategies every year. The recently acquired macromolecular-synthetic tools increase the precision and enable the synthesis of polymers with high control and...

journal_title：Biomacromolecules

authors： Olsén P,Odelius K,Albertsson AC

更新日期：2016-03-14 00:00:00

abstract：:A way to convert the volume change of a biochemo-mechanical gel into the change in liquid column length was developed. Our trial sensor device consisted of a small compartment for incorporating the gel, a flow channel with a filled dye solution, and a poly(dimethylsiloxane) (PDMS) diaphragm by which the gel and the dy...

journal_title：Biomacromolecules

authors： Suzuki H,Kumagai A,Ogawa K,Kokufuta E

更新日期：2004-03-01 00:00:00

abstract：:Hemicellulose-based hydrogels were prepared by radical polymerization of 2-hydroxyethyl methacrylate or poly(ethylene glycol) dimethacrylate with oligomeric hydrosoluble hemicellulose modified with well-defined amounts of methacrylic functions. The polymerization reaction was carried out in water at 40 degrees C using...

journal_title：Biomacromolecules

authors： Söderqvist Lindblad M,Albertsson AC,Ranucci E,Laus M,Giani E

更新日期：2005-03-01 00:00:00

abstract：:Amphiphilic block copolymer self-assembly provides a versatile means to prepare nanoscale micelles in solution. The utilization of these structures as targeted drug delivery vehicles has motivated efforts to prepare bioactive ligand-functionalized polymer micelles. The impact of ligand conjugation on micelle morpholog...

journal_title：Biomacromolecules

authors： Zupancich JA,Bates FS,Hillmyer MA

更新日期：2009-06-08 00:00:00

abstract：:In situ forming reduction-sensitive degradable nanogels were designed and developed based on poly(ethylene glycol)-b-poly(2-(hydroxyethyl) methacrylate-co-acryloyl carbonate) (PEG-P(HEMA-co-AC)) block copolymers for efficient loading as well as triggered intracellular release of proteins. PEG-P(HEMA-co-AC) copolymers ...

journal_title：Biomacromolecules

authors： Chen W,Zheng M,Meng F,Cheng R,Deng C,Feijen J,Zhong Z

更新日期：2013-04-08 00:00:00

abstract：:Light-harvesting antenna core (LH1-RC) complexes isolated from Rhodoseudomonas palustris were self-assembled on a gold electrode modified with self-assembled monolayers (SAMs) of the alkanethiols NH2(CH2)nSH, n = 2, 6, 8, 11; HOOC(CH2)7SH; and CH3(CH2)7SH, respectively. Adsorption of the LH1-RC complexes on the SAMs d...

journal_title：Biomacromolecules

authors： Kondo M,Nakamura Y,Fujii K,Nagata M,Suemori Y,Dewa T,Iida K,Gardiner AT,Cogdell RJ,Nango M

更新日期：2007-08-01 00:00:00

abstract：:There is a distinct need for antimicrobial compounds that can act at surfaces without leaching into the environment. Such materials should be easy to synthesize, be easy to apply to surfaces, and display reasonable levels of antimicrobial and antifungal activity. Here we describe such a surface-active compound and dem...

journal_title：Biomacromolecules

authors： Ravikumar T,Murata H,Koepsel RR,Russell AJ

更新日期：2006-10-01 00:00:00

abstract：:A systematic study is carried out to understand how physical and covalent crosslinks affect the mechanical properties of an eight-arm poly(ethyleneglycol)-based hydrogel. Heparin and heparin-binding peptide are used as a physical crosslinker, and an enzymatically cleavable peptide with a cysteine on each end serves as...

journal_title：Biomacromolecules

authors： Jeong KJ,Panitch A

更新日期：2009-05-11 00:00:00

abstract：:Novel polymer composites reinforced with an oriented cellulose nanocrystal (CNC) assembly were prepared from suspensions of CNC in aqueous 2-hydroxyethyl methacrylate (HEMA) via magnetic field application to the suspensions followed by polymerization treatment. The starting suspensions used at ∼6 wt % CNC separated in...

journal_title：Biomacromolecules

authors： Tatsumi M,Kimura F,Kimura T,Teramoto Y,Nishio Y

更新日期：2014-12-08 00:00:00

abstract：:The development of improved cryopreservative materials is necessary to enable complete recovery of living cells and tissue after frozen storage. Remarkably, poly(vinyl alcohol) (PVA) displays some of the same cryoprotective properties as many antifreeze proteins found in cold tolerant organisms. In particular, PVA is ...

journal_title：Biomacromolecules

authors： Burkey AA,Riley CL,Wang LK,Hatridge TA,Lynd NA

更新日期：2018-01-08 00:00:00

abstract：:We describe a facile method to amine functionalize and subsequently fluorescently label polymethacrylamides synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. RAFT-generated poly(N-(2-hydroxypropyl) methacrylamide-b-N-[3-(dimethylamino)propyl] methacrylamide) (poly(HPMA-b-DMAPMA)),...

journal_title：Biomacromolecules

authors： York AW,Scales CW,Huang F,McCormick CL

更新日期：2007-08-01 00:00:00

abstract：:PolyHIPEs show great promise as tissue engineering scaffolds due to the tremendous control of pore size and interconnectivity afforded by this technique. Highly porous, fully biodegradable scaffolds were prepared by polymerization of the continuous phase of high internal phase emulsions (HIPEs) containing the macromer...

journal_title：Biomacromolecules

authors： Christenson EM,Soofi W,Holm JL,Cameron NR,Mikos AG

更新日期：2007-12-01 00:00:00

abstract：:Changing gel structure and immobilization conditions led to a significant improvement in the covalent multipoint attachment of chymotrypsin on chitosan. The use of sodium alginate, gelatin, or kappa-carrageenan, activation with glutaraldehyde, glycidol, or epichlorohydrin, and addition of microorganisms followed by ce...

journal_title：Biomacromolecules

authors： Adriano WS,Mendonça DB,Rodrigues DS,Mammarella EJ,Giordano RL

更新日期：2008-08-01 00:00:00

abstract：:The Bacillus subtilis protease Proleather FG-F catalyzed the transesterification of inulin with vinyl acrylate (VA) in dimethylformamide (DMF). The reaction conversion for different VA concentrations was greater than 57% after 96 h at 50 degrees C. The degree of substitution (DS, defined as the amount of acrylate grou...

journal_title：Biomacromolecules

authors： Ferreira L,Carvalho R,Gil MH,Dordick JS

更新日期：2002-03-01 00:00:00