Polymerization of polyfunctional macromolecules: synthesis of a new class of high molecular weight poly(amino acid)s by oxidative coupling of phenol-containing precursor polymers.

abstract：:We report the synthesis of poly(methacrylic acid)-co-(oleyl methacrylate) with three different amounts of oleyl methacrylate and compare the ability of these polymers with that of poly(methacrylic acid)-co-(cholesteryl methacrylate) (PMA(c)) to noncovalently anchor liposomes to polymer layers. We subsequently assemble...

journal_title：Biomacromolecules

authors： Hosta-Rigau L,Chandrawati R,Saveriades E,Odermatt PD,Postma A,Ercole F,Breheney K,Wark KL,Städler B,Caruso F

更新日期：2010-12-13 00:00:00

abstract：:Glycopolymer-polypeptide triblock copolymers of the structure, poly(l-alanine)-b-poly(2-acryloyloxyethyl-lactoside)-b-poly(l-alanine) (AGA), have been synthesized by sequential atom transfer radical polymerization (ATRP) and ring-opening polymerization (ROP). Controlled free radical polymerization of 2-O-acryloyl-oxye...

journal_title：Biomacromolecules

authors： Dong CM,Sun XL,Faucher KM,Apkarian RP,Chaikof EL

更新日期：2004-01-01 00:00:00

abstract：:The oxidation reaction of regenerated cellulose fibers mediated by N-hydroxyphthalimide (NHPI) and various cocatalysts at room temperature for different time intervals and various amounts of low concentration sodium hypochlorite solution has been investigated to produce oxidized cellulose (OC), a biocompatible and bio...

journal_title：Biomacromolecules

authors： Coseri S,Nistor G,Fras L,Strnad S,Harabagiu V,Simionescu BC

更新日期：2009-08-10 00:00:00

abstract：:A temperature-responsive hydrogel composed of aqueous methylcellulose (MC) blended with distinct concentrations of PBS was prepared and characterized. The developed MC hydrogel underwent a sol-gel reversible transition upon heating or cooling at approximately 32 degrees C. This temperature-responsive hydrogel was empl...

journal_title：Biomacromolecules

authors： Yang MJ,Chen CH,Lin PJ,Huang CH,Chen W,Sung HW

更新日期：2007-09-01 00:00:00

abstract：:As with many other biosourced colloids, chitin nanocrystals (ChNCs) can form liquid crystalline phases with chiral nematic ordering. In this work, we demonstrate that it is possible to finely tune the liquid crystalline behavior of aqueous ChNC suspensions finely. Such control was made possible by carefully studying h...

journal_title：Biomacromolecules

authors： Narkevicius A,Steiner LM,Parker RM,Ogawa Y,Frka-Petesic B,Vignolini S

更新日期：2019-07-08 00:00:00

abstract：:Silk fibroin (SF) protein, produced by silkworm Bombyx mori, is a promising biomaterial, while sophorolipid (SL) is an amphiphilic functional biosurfactant synthesized by nonpathogenic yeast Candida bombicola. SL is a mixture of two forms, acidic (ASL) and lactonic (LSL), which when added to SF results in accelerated ...

journal_title：Biomacromolecules

authors： Dubey P,Kumar S,Aswal VK,Ravindranathan S,Rajamohanan PR,Prabhune A,Nisal A

更新日期：2016-10-10 00:00:00

abstract：:A novel poly(epsilon-caprolactone)-organosiloxane hybrid material containing calcium salt (Si-O-PCL) was prepared and evaluated as a bioactive and degradable bone substitute material. The Si-O-PCL hybrid was synthesized by the end-capping of 3-isocyanatopropyl triethoxysilane with alpha,omega-hydroxyl PCL following so...

journal_title：Biomacromolecules

authors： Rhee SH,Lee YK,Lim BS,Yoo JJ,Kim HJ

更新日期：2004-07-01 00:00:00

abstract：:As a result of improved relevance to in vivo physiology, in vitro studies are increasingly performed in diverse, three-dimensional (3D) biomaterials. However, material-cell type pairing effects on cytokine availability remain unclear. We cultured five cell types in agarose, alginate, collagen, Matrigel, or RGD-functio...

journal_title：Biomacromolecules

authors： Regier MC,Montanez-Sauri SI,Schwartz MP,Murphy WL,Beebe DJ,Sung KE

更新日期：2017-03-13 00:00:00

abstract：:Nanofibrous biocomposite scaffolds of type I collagen and nanohydroxyapatite (nanoHA) of varying compositions (wt %) were prepared by electrostatic cospinning. The scaffolds were characterized for structure and morphology by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), atomic fo...

journal_title：Biomacromolecules

authors： Thomas V,Dean DR,Jose MV,Mathew B,Chowdhury S,Vohra YK

更新日期：2007-02-01 00:00:00

abstract：:As a first step toward utilizing self-assembling peptide scaffolds to create tunable matrices for drug delivery, peptide RADAFI and RADAFII, containing the same amino acid composition but different positions of one phenylalanine residue, scaffolds were prepared for controlled release of chiral enantiomers. The release...

journal_title：Biomacromolecules

authors： Zhao Y,Tanaka M,Kinoshita T,Higuchi M,Tan T

更新日期：2009-12-14 00:00:00

abstract：:Poly((N-vinylpyrrolidone)-block-poly(vinyl acetate)) (PVP-b-PVAc) block copolymers of varying molecular weight and hydrophobic block lengths were synthesized via controlled radical polymerization and investigated as carriers for the solubilization of highly hydrophobic riminophenazine compounds. These compounds have r...

journal_title：Biomacromolecules

authors： Bailly N,Thomas M,Klumperman B

更新日期：2012-12-10 00:00:00

abstract：:Sjögren's syndrome (SS) is an autoimmune disease associated with severe exocrinopathy, which is characterized by profound lymphocytic infiltration (dacryoadenitis) and loss of function of the tear-producing lacrimal glands (LGs). Systemic administration of Rapamycin (Rapa) significantly reduces LG inflammation in the ...

journal_title：Biomacromolecules

authors： Ju Y,Edman MC,Guo H,Janga SR,Peddi S,Louie SG,Junge JA,MacKay JA,Hamm-Alvarez SF

更新日期：2020-12-27 00:00:00

abstract：:The introduction of polymers into a chiral nematic cellulose nanocrystal (CNC) matrix allows for the tuning of optical and mechanical properties, enabling the development of responsive photonic materials. In this study, we explored the incorporation of hydroxypropyl cellulose (HPC) into a CNC film prepared by slow eva...

journal_title：Biomacromolecules

authors： Walters CM,Boott CE,Nguyen TD,Hamad WY,MacLachlan MJ

更新日期：2020-03-09 00:00:00

abstract：:Controlled reeling is a powerful tool to investigate the details of silk processing. However, consistent forced reeling of silkworms is hindered by the significant degree of behaviorally induced variation caused by the animal. This paper proposes silkworm paralysis as a novel method to control the animal and thus in v...

journal_title：Biomacromolecules

authors： Mortimer B,Holland C,Vollrath F

更新日期：2013-10-14 00:00:00

abstract：:Amphiphilic block copolymers containing polypeptides can self-assemble into a variety of nonspherical structures arising from strong interactions between peptide units. Here, we report the synthesis of a pH-responsive poly(ethyl glycol)-block-poly(l-glutamic acid)-block-poly(N-octylglycine) (PEG-b-PGA-b-PNOG) triblock...

journal_title：Biomacromolecules

authors： Ni Y,Sun J,Wei Y,Fu X,Zhu C,Li Z

更新日期：2017-10-09 00:00:00

abstract：:Because of their association with debilitating diseases and their potential applications in developing novel bionanomaterials, highly ordered amyloid fibrils have recently received considerable attention. While many studies have thus far focused on amyloid fibrils made with short peptides containing just one steric zi...

journal_title：Biomacromolecules

authors： Dai B,Sargent CJ,Gui X,Liu C,Zhang F

更新日期：2019-05-13 00:00:00

abstract：:Development of versatile nanoscale platforms for cancer diagnosis and therapy is of great importance for applications in translational medicine. In this work, we present the use of γ-polyglutamic acid (γ-PGA) nanogels (NGs) to load polypyrrole (PPy) for thermal/photoacoustic (PA) imaging and radiotherapy (RT)-sensitiz...

journal_title：Biomacromolecules

authors： Zhou Y,Hu Y,Sun W,Lu S,Cai C,Peng C,Yu J,Popovtzer R,Shen M,Shi X

更新日期：2018-06-11 00:00:00

abstract：:N-(3-Aminopropyl)pyrrole was covalently coupled with alginate in an aqueous-phase reaction by means of carbodiimide-mediated activation chemistry to provide a pyrrole-alginate conjugate for subsequent use in biosensor applications. The pyrrole-alginate conjugate was quantified by UV spectroscopy at 230 nm, by an HPSEC...

journal_title：Biomacromolecules

authors： Abu-Rabeah K,Polyak B,Ionescu RE,Cosnier S,Marks RS

更新日期：2005-11-01 00:00:00

abstract：:New applications in regenerative biotechnology require the ability to understand and control protein-surface interactions on micrometer and submicrometer length scales. Evidence presented here shows that micropatterned amphiphilic comb polymer films exhibit a pretreatment-dependent behavior with respect to protein ads...

journal_title：Biomacromolecules

authors： Zhang Z,Ma H,Hausner DB,Chilkoti A,Beebe TP Jr

更新日期：2005-11-01 00:00:00

abstract：:A His-tagged coiled coil stem loop peptide with stable secondary structure was designed and biosynthesized. A series of oligopeptides related to the EBV envelope glycoprotein 350/220 N-terminal nonapeptide as potential CD21 receptor-binding epitopes were engineered into the loop region of the peptide scaffold. It was ...

journal_title：Biomacromolecules

authors： Tang A,Kopecek J

更新日期：2002-05-01 00:00:00

abstract：:Hollow poly(6-O-acryloyl-alpha-D-galactopyranose) (PAGP) nanospheres were prepared in a facile manner using the RAFT (reversible addition fragmentation chain transfer) process. Initially, an amphiphilic block copolymer, poly(lactide)-block-poly(6-O-acryloyl-alpha-D-galactopyranose) (PLA-b-PAGP), was synthesized using ...

journal_title：Biomacromolecules

authors： Ting SR,Gregory AM,Stenzel MH

更新日期：2009-02-09 00:00:00

abstract：:Chitosan is a well sought-after polysaccharide in biomedical applications and has been blended with various macromolecules to mitigate undesirable properties. However, the effects of blending on the unique antibacterial activity of chitosan as well as changes in fatigue and degradation properties are not well understo...

journal_title：Biomacromolecules

authors： Sarasam AR,Krishnaswamy RK,Madihally SV

更新日期：2006-04-01 00:00:00

abstract：:In tissue engineering, incorporation of bone morphogenetic protein-2 (BMP-2) into biomaterial scaffolds is an attractive strategy to stimulate bone repair. However, suboptimal release of BMP-2 remains a great concern, which may cause unfavorable bone formation as well as severe inflammation. In this study, genipin-cro...

journal_title：Biomacromolecules

authors： Zhang Q,Tan K,Zhang Y,Ye Z,Tan WS,Lang M

更新日期：2014-01-13 00:00:00

abstract：:Regulating cell migration dynamics is of significance in tissue engineering and regenerative medicine. A 3D scaffold was created to provide various topographies based on a poly(ε-caprolactone) (PCL) self-induced nanohybrid shish-kebab structure, which consisted of aligned PCL nanofibers and spaced PCL crystal lamellae...

journal_title：Biomacromolecules

authors： Guo X,Wang X,Li X,Jiang YC,Han S,Ma L,Guo H,Wang Z,Li Q

更新日期：2020-03-09 00:00:00

abstract：:Lignin is a natural, renewable biopolymer synthesized by plants. It is a macromolecule consisting of aromatic structures with high density of functional groups making it an ideal precursor for the design of sustainable biomaterials for applications such as drug delivery. The rational design of these materials requires...

journal_title：Biomacromolecules

authors： Salentinig S,Schubert M

更新日期：2017-08-14 00:00:00

abstract：:Inulin, the polydisperse reserve polysaccharide from chicory, has been modified by carbamoylation in organic solvents. The reaction of inulin with a range of alkyl isocyanates resulted, after crystalization, in a variety of carbamoylated inulins from which the interfacial properties were determined. The medium and lon...

journal_title：Biomacromolecules

authors： Stevens CV,Meriggi A,Peristeropoulou M,Christov PP,Booten K,Levecke B,Vandamme A,Pittevils N,Tadros TF

更新日期：2001-01-01 00:00:00

abstract：:Spider silk has been extensively studied for its outstanding mechanical properties. Partial intermediate and C-terminal sequences of different spider silk proteins have been determined, and during the past decade also N-terminal domains have been characterized. However, only some of these N-terminal domains have been ...

journal_title：Biomacromolecules

authors： Rising A,Hjälm G,Engström W,Johansson J

更新日期：2006-11-01 00:00:00

abstract：:The fate of intravenously injected nanoparticles (NPs) is significantly affected by nano-protein interaction and corona formation. However, such an interaction between NPs and digestive enzymes occurring in the gastrointestinal tract (GIT) and its impacts on epithelial cell uptake are little known. We synthesized the ...

journal_title：Biomacromolecules

authors： Peng Q,Liu J,Zhang T,Zhang TX,Zhang CL,Mu H

更新日期：2019-04-08 00:00:00

abstract：:Effects of molecular weight (Lc) and field strength (E) on conformation of polymer chains and their density are investigated at the surface and bulk of a driven chain system in three dimensions with a Monte Carlo simulation. As the polymer chains deposit on the surface, a linear density gradient develops in low field....

journal_title：Biomacromolecules

authors： Foo GM,Pandey RB

更新日期：2000-10-01 00:00:00

abstract：:Amphiphilic block copolymer self-assembly provides a versatile means to prepare nanoscale micelles in solution. The utilization of these structures as targeted drug delivery vehicles has motivated efforts to prepare bioactive ligand-functionalized polymer micelles. The impact of ligand conjugation on micelle morpholog...

journal_title：Biomacromolecules

authors： Zupancich JA,Bates FS,Hillmyer MA

更新日期：2009-06-08 00:00:00