The Influence of Biomaterials on Cytokine Production in 3D Cultures.

abstract：:New aspects concerning the mechanism of formation of chitosan physical hydrogels without any cross-linking agent were studied. The gelation took place during the evaporation of a hydroalcoholic solution of chitosan. We first demonstrated that it was possible to form a physical hydrogel from a hydrochloride form of chi...

journal_title：Biomacromolecules

authors： Boucard N,Viton C,Domard A

更新日期：2005-11-01 00:00:00

abstract：:Algae constitute a largely available, low value material from renewable resources of marine origin to be used for the production of eco-compatible composites. Fibers of the green alga Ulva armoricana from the French coast were positively evaluated for the production of composites with a hydrophilic, eco-compatible pol...

journal_title：Biomacromolecules

authors： Chiellini E,Cinelli P,Ilieva VI,Martera M

更新日期：2008-03-01 00:00:00

abstract：:We show that functionalizing polymer-coated colloidal nanoplatelets with guanosine groups allows synergistic increase of mechanical properties in nacre-mimetic lamellar self-assemblies. Anionic montmorillonite (MTM) was first coated using cationic poly(diallyldimethylammonium chloride) (PDADMAC) to prepare core-shell ...

journal_title：Biomacromolecules

authors： Martikainen L,Walther A,Seitsonen J,Berglund L,Ikkala O

更新日期：2013-08-12 00:00:00

abstract：:For efficient reversal of multidrug resistance (MDR) in chemotherapy for breast cancer, multifunctional self-assembled nanoparticles (MSN) based on a new amphiphilic copolymer consisting of bioreducible poly[bis(2-hydroxylethyl)-disulfide-diacrylate-β-tetraethylenepentamine] and polycaprolactone (PBD-PCL) were constru...

journal_title：Biomacromolecules

authors： Yin Q,Shen J,Zhang Z,Yu H,Chen L,Gu W,Li Y

更新日期：2013-07-08 00:00:00

abstract：:Hydrogels are promising materials for biomedical applications such as tissue engineering and controlled drug release. In the past two decades, the peptide hydrogel subclass has attracted an increasing level of interest from the scientific community because of its numerous advantages, such as biocompatibility, biodegra...

journal_title：Biomacromolecules

authors： Oyen E,Martin C,Caveliers V,Madder A,Van Mele B,Hoogenboom R,Hernot S,Ballet S

更新日期：2017-03-13 00:00:00

abstract：:Optimal curcumin delivery for medicinal applications requires a drug delivery system that both solubilizes curcumin and prevents degradation. To achieve this, curcumin has been encapsulated in submicrometer chitosan/Tween 20 particles via a benchtop spray-drying process. Spray-drying parameters have been optimized usi...

journal_title：Biomacromolecules

authors： O'Toole MG,Henderson RM,Soucy PA,Fasciotto BH,Hoblitzell PJ,Keynton RS,Ehringer WD,Gobin AS

更新日期：2012-08-13 00:00:00

abstract：:Cellular model systems are essential platforms used across multiple research fields for exploring the fundaments of biology and biochemistry. Here, we present giant plasma membrane vesicles (GPMVs) as a platform of cell-like compartments that will facilitate the study of particles within a biorelevant environment and ...

journal_title：Biomacromolecules

authors： Zartner L,Garni M,Craciun I,Einfalt T,Palivan CG

更新日期：2021-01-11 00:00:00

abstract：:A new, convenient pathway is developed to synthesize highly hydrolytically labile poly(ortho ester amide) (POEA) copolymers that overcomes some of the major weaknesses of the traditional methods of synthesizing poly(ortho esters) and their derivatives. A diamine monomer containing a built-in, stabilized ortho ester gr...

journal_title：Biomacromolecules

authors： Tang R,Palumbo RN,Ji W,Wang C

更新日期：2009-04-13 00:00:00

abstract：:Spiders have evolved a complex system of silk producing glands. Each of the glands produces silk with strength and elasticity tailored to its biological purpose. Sequence analysis of the major ampullate silk reveals four highly conserved concatenated blocks of amino acids: (GA) n , A n , GPGXX, and GGX. While the GPGX...

journal_title：Biomacromolecules

authors： Brooks AE,Stricker SM,Joshi SB,Kamerzell TJ,Middaugh CR,Lewis RV

更新日期：2008-06-01 00:00:00

abstract：:A new 320-member polymer library of end-modified poly(β-amino ester)s was synthesized. This library was chosen such that small differences to the structures of component backbone, side-chain, and end-group monomers could be systematically and simultaneously evaluated. The in vitro transfection efficacy and cytotoxicit...

journal_title：Biomacromolecules

authors： Sunshine JC,Akanda MI,Li D,Kozielski KL,Green JJ

更新日期：2011-10-10 00:00:00

abstract：:Mechanically fibrillated cellulose nanofibrils (CNFs) have attracted special attention as building blocks for the development of advanced materials and composites. A correlation exists between CNF morphology and the properties of the materials they form. However, this correlation is often evaluated indirectly by proce...

journal_title：Biomacromolecules

authors： Mattos BD,Tardy BL,Rojas OJ

更新日期：2019-07-08 00:00:00

abstract：:Thermoresponsive anionic copolymer brushes, poly(N-isopropylacrylamide-co-acrylic acid-co-tert-butylacrylamide) [P(IPAAm-co-AAc-co-tBAAm)], were grafted onto a monolithic silica rod column through surface-initiated atom-transfer radical polymerization (ATRP) to prepare an effective thermoresponsive anionic chromatogra...

journal_title：Biomacromolecules

authors： Nagase K,Kobayashi J,Kikuchi A,Akiyama Y,Kanazawa H,Okano T

更新日期：2014-04-14 00:00:00

abstract：:Spider silk has been extensively studied for its outstanding mechanical properties. Partial intermediate and C-terminal sequences of different spider silk proteins have been determined, and during the past decade also N-terminal domains have been characterized. However, only some of these N-terminal domains have been ...

journal_title：Biomacromolecules

authors： Rising A,Hjälm G,Engström W,Johansson J

更新日期：2006-11-01 00:00:00

abstract：:Vascular grafts that can support total replacement and maintenance by the body of the injured vessel would improve outcomes of major surgical reconstructions. Building scaffolds using components of the native vessel can encourage biological recognition by native cells as well as mimic mechanical characteristics of the...

journal_title：Biomacromolecules

authors： Bracaglia LG,Messina M,Winston S,Kuo CY,Lerman M,Fisher JP

更新日期：2017-11-13 00:00:00

abstract：:Recently antifreeze proteins (AFP) have been the subject of many structure-function relationship studies regarding their antifreeze activity. Attempts have been made to elucidate the structure-function relationship by various amino acid substitutions, but to our knowledge there has been no successful from first princi...

journal_title：Biomacromolecules

authors： Wierzbicki A,Knight CA,Rutland TJ,Muccio DD,Pybus BS,Sikes CS

更新日期：2000-07-01 00:00:00

abstract：:Self-cross-linking polyelectrolytes are used to strengthen the surface of calcium alginate beads for cell encapsulation. Poly([2-(methacryloyloxy)ethyl]trimethylammonium chloride), containing 30 mol % 2-aminoethyl methacrylate, and poly(sodium methacrylate), containing 30 mol % 2-(methacryloyloxy)ethyl acetoacetate, w...

journal_title：Biomacromolecules

authors： Mazumder MA,Shen F,Burke NA,Potter MA,Stöver HD

更新日期：2008-09-01 00:00:00

abstract：:A way to convert the volume change of a biochemo-mechanical gel into the change in liquid column length was developed. Our trial sensor device consisted of a small compartment for incorporating the gel, a flow channel with a filled dye solution, and a poly(dimethylsiloxane) (PDMS) diaphragm by which the gel and the dy...

journal_title：Biomacromolecules

authors： Suzuki H,Kumagai A,Ogawa K,Kokufuta E

更新日期：2004-03-01 00:00:00

abstract：:Self-assembled hydrogen-bonded networks of the polysaccharide pectin, a mechanically functional component of plant cell walls, have been of recent interest as biomimetic exemplars of physical gels, and the microrheological and strain-stiffening behaviors have been previously investigated. Despite this detailed rheolog...

journal_title：Biomacromolecules

authors： Mansel BW,Chu CY,Leis A,Hemar Y,Chen HL,Lundin L,Williams MA

更新日期：2015-10-12 00:00:00

abstract：:A comprehensive understanding of the mechanism by which type I collagen (Col) interacts with hydroxyapatite nanoparticles (Hap NPs) in aqueous solutions is a pivotal step for guiding the design of biologically relevant nanocomposites with controlled hierarchical structure. In this paper we use a variety of Hap NPs dif...

journal_title：Biomacromolecules

authors： Colaço E,Brouri D,Aissaoui N,Cornette P,Dupres V,Domingos RF,Lambert JF,Maisonhaute E,Kirat KE,Landoulsi J

更新日期：2019-12-09 00:00:00

abstract：:Preparations of the highly ordered monoantennary, homofunctional diantennary, and heterofunctional diantennary neoglycopolymers of α-d-mannose and β-d-glucose residues were achieved via ring-opening metathesis polymerization. Isothermal titration calorimetry measurements of these synthetic neoglycopolymers with Concan...

journal_title：Biomacromolecules

authors： Loka RS,McConnell MS,Nguyen HM

更新日期：2015-12-14 00:00:00

abstract：:Deep eutectic solvents promoted the stabilization of the collapsed state of elastin-like recombinamers - and the subsequent formation of aggregates - upon the loss of the structural water molecules involved in hydrophobic hydration. Cryo-etch scanning electron microscopy allowed the observation of these aggregates i...

journal_title：Biomacromolecules

authors： Nardecchia S,Gutiérrez MC,Ferrer ML,Alonso M,López IM,Rodríguez-Cabello JC,del Monte F

更新日期：2012-07-09 00:00:00

abstract：:Glycopolymer-polypeptide triblock copolymers of the structure, poly(l-alanine)-b-poly(2-acryloyloxyethyl-lactoside)-b-poly(l-alanine) (AGA), have been synthesized by sequential atom transfer radical polymerization (ATRP) and ring-opening polymerization (ROP). Controlled free radical polymerization of 2-O-acryloyl-oxye...

journal_title：Biomacromolecules

authors： Dong CM,Sun XL,Faucher KM,Apkarian RP,Chaikof EL

更新日期：2004-01-01 00:00:00

abstract：:Nanocoating of individual mammalian cells with polymer layers has been of increasing interest in biotechnology and biomedical engineering applications. Electrostatic layer-by-layer (LbL) deposition of polyelectrolytes on negatively charged cell surfaces has been utilized for cell nanocoatings using synthetic or natura...

journal_title：Biomacromolecules

authors： Hasturk O,Sahoo JK,Kaplan DL

更新日期：2020-07-13 00:00:00

abstract：:PLGA nanoparticles are among the most studied polymer nanoformulations for several drugs against different kinds of malignant diseases, thanks to their in vivo stability and tumor localization exploiting the well-documented "enhanced permeation and retention" (EPR) effect. In this paper, we have developed uniform curc...

journal_title：Biomacromolecules

authors： Verderio P,Bonetti P,Colombo M,Pandolfi L,Prosperi D

更新日期：2013-03-11 00:00:00

abstract：:This study describes the first use of laccase-lipase enzymatic reaction for the synthesis of novel perfectly structured alternating copolymers. Initially, six types of complexing agents, linear(A)-linear(B), linear(A)-linear(B)-linear(A), linear-dendritic, dendritic-linear-dendritic, linear-hyperbranched, and hyperbra...

journal_title：Biomacromolecules

authors： Scheibel DM,Gitsov I

更新日期：2019-02-11 00:00:00

abstract：:Branched amphiphilic copolymers were synthesized through the reversible addition-fragmentation chain transfer (RAFT) chain extension of a poly(methyl acrylate) macro-chain transfer agent using a protected galactose monomer and a polymerizable chain transfer agent branching unit. After galactose deprotection, the copol...

journal_title：Biomacromolecules

authors： Liau WT,Bonduelle C,Brochet M,Lecommandoux S,Kasko AM

更新日期：2015-01-12 00:00:00

abstract：:Orb-weaving spider silk fibers are assembled from very large, highly repetitive proteins. The repeated segments contain, in turn, short, simple, and repetitive amino acid motifs that account for the physical and mechanical properties of the assembled fiber. Of the six orb-weaver silk fibroins, the piriform silk that m...

journal_title：Biomacromolecules

authors： Perry DJ,Bittencourt D,Siltberg-Liberles J,Rech EL,Lewis RV

更新日期：2010-11-08 00:00:00

abstract：:The complement system plays an important role in innate and adaptive immunity, which suggests that complement activation could be exploited as a potential strategy for vaccine adjuvants. Here we explored the potential of chitosan-based microparticles (CS-NH2 MPs) as a vaccine adjuvant with an active surface for comple...

journal_title：Biomacromolecules

authors： Liu Y,Yin Y,Wang L,Zhang W,Chen X,Yang X,Xu J,Ma G

更新日期：2013-09-09 00:00:00

abstract：:In the present study we describe the synthesis, wet spinning, mechanical testing, and degradation of poly(urethane urea)s (PUURs) intended for clinical use in anterior cruciate ligament (ACL) reconstruction. The effects of soft segment chemical composition and molar mass and the kind of diamine chain extender on the m...

journal_title：Biomacromolecules

authors： Gisselfält K,Edberg B,Flodin P

更新日期：2002-09-01 00:00:00

abstract：:There is a lack of hydrogel materials whose properties can be tuned at the point of use. Biological hydrogels, such as collagen, gelate at physiological temperatures; however, they are not always ideal as scaffolds because of their low mechanical strength. Their mechanics can be improved through cross-linking and chem...

journal_title：Biomacromolecules

authors： Barnes AL,Genever PG,Rimmer S,Coles MC

更新日期：2016-03-14 00:00:00