Evaluation of a novel poly(epsilon-caprolactone)-organosiloxane hybrid material for the potential application as a bioactive and degradable bone substitute.

abstract：:In a previous study, we have reported chemical synthesis of novel aliphatic poly(butylene succinate-co-cyclic carbonate) P(BS-co-CC)s bearing various functionalizable carbonate building blocks, and this work will continue to present our new studies on their enzymatic degradation and in vitro cell biocompatibility assa...

journal_title：Biomacromolecules

authors： Yang J,Tian W,Li Q,Li Y,Cao A

更新日期：2004-11-01 00:00:00

abstract：:The present study demonstrates the controlled synthesis and biological potential of poly( N-acryloyl-l-methionine methyl sulfonium salt)s (poly(A-Met(S+)-OH)s), which mimic dimethylsulfoniopropionate (DMSP), a compound produced by marine algae to protect their proteins. The novel sulfonium-containing zwitterionic poly...

journal_title：Biomacromolecules

authors： Imamura R,Mori H

更新日期：2019-02-11 00:00:00

abstract：:Fluorescence and circular dichroism spectroscopy were used to monitor the conformational transition of regenerated Bombyx mori silk fibroin (RSF) in aqueous solutions under different conditions. According to the analysis of fluorescence spectra using anilinonaphthalene-8-sulfonic acid magnesium salt (ANS) as an extern...

journal_title：Biomacromolecules

authors： Yang Y,Shao Z,Chen X,Zhou P

更新日期：2004-05-01 00:00:00

abstract：:A novel approach for the preparation of nano- and microcapsules in aqueous solutions by using thermoresponsive polymer (TRP) templates (mesoglobules) is described. The method comprised three steps: formation of mesoglobules, coating the templates by seeded radical copolymerization, followed by core dissolution and cor...

journal_title：Biomacromolecules

authors： Haladjova E,Toncheva-Moncheva N,Apostolova MD,Trzebicka B,Dworak A,Petrov P,Dimitrov I,Rangelov S,Tsvetanov CB

更新日期：2014-12-08 00:00:00

abstract：:Adhesive hydrogels were prepared by copolymerizing dopamine methacrylamide with either acrylic acid (AAc) or N-(3-aminopropyl)methacrylamide hydrochloride (APMH). The effect of incorporating the anionic and cationic side chains on the oxidation state of catechol was characterized using the FOX assay to track the produ...

journal_title：Biomacromolecules

authors： Narkar AR,Kelley JD,Pinnaratip R,Lee BP

更新日期：2018-05-14 00:00:00

abstract：:One of the major drawbacks found in most bone tissue engineering approaches developed so far consists in the lack of strategies to promote vascularisation. Some studies have addressed different issues that may enhance vascularisation in tissue engineered constructs, most of them involving the use of growth factors (GF...

journal_title：Biomacromolecules

authors： Santo VE,Frias AM,Carida M,Cancedda R,Gomes ME,Mano JF,Reis RL

更新日期：2009-06-08 00:00:00

abstract：:This paper presents the formation of a novel biomimetic interface consisting of an electrolessly deposited gold film overlaid with a tethered bilayer lipid membrane (tBLM). Self-assembly of colloidal gold particles was used to create an electrolessly deposited gold film on a glass slide. The properties of the film wer...

journal_title：Biomacromolecules

authors： Kohli N,Hassler BL,Parthasarathy L,Richardson RJ,Ofoli RY,Worden RM,Lee I

更新日期：2006-12-01 00:00:00

abstract：:Nanoparticles (NPs) composed of chitosan (CS) and poly(gamma-glutamic acid) (gamma-PGA) were prepared by a simple ionic-gelation method for oral insulin delivery. Fourier transform infrared (FT-IR) spectra indicated that CS and gamma-PGA were ionized at pH 2.5-6.6, while X-ray diffractograms demonstrated that the crys...

journal_title：Biomacromolecules

authors： Lin YH,Mi FL,Chen CT,Chang WC,Peng SF,Liang HF,Sung HW

更新日期：2007-01-01 00:00:00

abstract：:Greener alternatives to synthetic polymers are constantly being investigated and sought after. Chitin is a natural polysaccharide that gives structural support to crustacean shells, insect exoskeletons, and fungal cell walls. Like cellulose, chitin resides in nanosized structural elements that can be isolated as nanof...

journal_title：Biomacromolecules

authors： Nawawi WMFBW,Jones M,Murphy RJ,Lee KY,Kontturi E,Bismarck A

更新日期：2020-01-13 00:00:00

abstract：:Most biopolymers exist in a plasticized state, whether it is naturally with water or unnaturally with glycerol or other suitable polyol, to make a flexible material. We have found that the extent to which a biopolymer can be plasticized is dependent on its molecular and higher order structures outside of simply molecu...

journal_title：Biomacromolecules

authors： Athamneh AI,Griffin M,Whaley M,Barone JR

更新日期：2008-11-01 00:00:00

abstract：:Small-angle X-ray scattering (SAXS) experiments with in situ dehydration have been performed on small bundles of flax fibers. Analysis indicated that the structure of the cellulose microfibrils is consistent with a cross section of approximately 10 x 50 A2. The microfibril misalignment was Gaussian with a full width a...

journal_title：Biomacromolecules

authors： Astley OM,Donald AM

更新日期：2001-10-01 00:00:00

abstract：:Agmatine-containing bioreducible polymer, poly(cystaminebis(acrylamide)-agmatine) (poly(CBA-AG)) was synthesized for gene delivery systems. It could form 200-300 nm sized and positively charged polyplexes with pDNA, which could release pDNA in reducing the environment due to the internal disulfide bonds cleavage. Poly...

journal_title：Biomacromolecules

authors： Choi JY,Ryu K,Lee GJ,Kim K,Kim TI

更新日期：2015-09-14 00:00:00

abstract：:Hydrogels with pH-sensitive poly(acrylic acid) (PAAc) chains and biodegradable acryloyl-poly(-caprolactone)-2-hydroxylethyl methacrylate (AC-PCL-HEMA) chains were designed and synthesized. The morphology of hydrogel was observed by scanning electron microscopy. The degradation of the hydrogel in the presence of Pseudo...

journal_title：Biomacromolecules

authors： Wu DQ,Sun YX,Xu XD,Cheng SX,Zhang XZ,Zhuo RX

更新日期：2008-04-01 00:00:00

abstract：:A library-orientated approach is used to gain understanding of the interactions of well-defined nanoparticles with primary human endothelial cells, which are a key component of the vasculature. Fifteen sequentially modified gold nanoparticles (AuNPs) based on three different core sizes (18, 35, 65 nm) and five polymer...

journal_title：Biomacromolecules

authors： Freese C,Gibson MI,Klok HA,Unger RE,Kirkpatrick CJ

更新日期：2012-05-14 00:00:00

abstract：:Spider aciniform (or wrapping) silk is the toughest of the seven types of spider silks/glue due to a combination of high elasticity and strength. Like most spider silk proteins (spidroins), aciniform spidroin (AcSp1) has a large core repetitive domain flanked by relatively short N- and C-terminal nonrepetitive domains...

journal_title：Biomacromolecules

authors： Xu L,Lefèvre T,Orrell KE,Meng Q,Auger M,Liu XQ,Rainey JK

更新日期：2017-11-13 00:00:00

abstract：:Synthesis of novel zwitterionic block copolypeptides, poly(N-isopropylacrylamide)-block-poly(L-glutamic acid-co-L-lysine) [PNiPAM(n)(PLG(x)-co-PLLys(y))m , where n is the number-average degree of polymerization (DP(n)) of PNiPAM block, x and y are the mole fraction of glutamic acid and lysine residues, respectively, a...

journal_title：Biomacromolecules

authors： Li J,Wang T,Wu D,Zhang X,Yan J,Du S,Guo Y,Wang J,Zhang A

更新日期：2008-10-01 00:00:00

abstract：:Amino groups were covalently introduced onto a polycaprolactone (PCL) surface by the reaction between 1,6-hexanediamine and the ester groups of PCL. The occurrence of the aminolysis and the introduction of free NH(2) groups were verified qualitatively by fluorescence spectroscopy, where rhodamine B isothiocyanate was ...

journal_title：Biomacromolecules

authors： Zhu Y,Gao C,Liu X,Shen J

更新日期：2002-11-01 00:00:00

abstract：:This study clarifies the contribution to overall osmotic kinetics of colloid osmotic pressure (Pi) and the interaction of synthetic colloids with the membrane. Solutions (6%) of dextran with weight average molecular weight (MW(w)) 68 800 (DEX 70), dextran with MW(w) 40 000 (DEX 40), hydroxyethyl starch with MW(w) 70 0...

journal_title：Biomacromolecules

authors： Tatara T,Tashiro C

更新日期：2005-05-01 00:00:00

abstract：:Antibacterial nanodevices could bring coatings of plastic materials and wound dressings a big step forward if the release of the antibacterial agents could be triggered by the presence of the bacteria themselves. Here, we show that novel hyaluronic acid (HA)-based nanocapsules containing the antimicrobial agent polyhe...

journal_title：Biomacromolecules

authors： Baier G,Cavallaro A,Vasilev K,Mailänder V,Musyanovych A,Landfester K

更新日期：2013-04-08 00:00:00

abstract：:In the present study, novel bionanocomposite materials with tunable properties were successfully prepared using a poly(lactic acid) (PLA) matrix and acetylated microfibrillated cellulose (MFC) as reinforcing agent. The acetylation of MFC was confirmed by FTIR and (13)C CP-MAS NMR spectroscopies. The grafting of acetyl...

journal_title：Biomacromolecules

authors： Tingaut P,Zimmermann T,Lopez-Suevos F

更新日期：2010-02-08 00:00:00

abstract：:Anionic copolymer systems containing sulfated monomers have great potential for delivery of cationic therapeutics, but N-isopropylacrylamide (NIPAm) 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) copolymer nanoparticles have seen limited characterization to date with regard to physical properties relevant to load...

journal_title：Biomacromolecules

authors： Bartlett RL 2nd,Medow MR,Panitch A,Seal B

更新日期：2012-04-09 00:00:00

abstract：:As a programmable biopolymer, DNA has shown great potential in the fabrication and construction of nanometer-scale assemblies and devices. In this report, we described a strategy for efficient manipulation of gold nanoparticle-bound DNA using restriction endonuclease. The digestion efficiency of this restriction enzym...

journal_title：Biomacromolecules

authors： Qin WJ,Yung LY

更新日期：2006-11-01 00:00:00

abstract：:Mechanically fibrillated cellulose nanofibrils (CNFs) have attracted special attention as building blocks for the development of advanced materials and composites. A correlation exists between CNF morphology and the properties of the materials they form. However, this correlation is often evaluated indirectly by proce...

journal_title：Biomacromolecules

authors： Mattos BD,Tardy BL,Rojas OJ

更新日期：2019-07-08 00:00:00

abstract：:We report the rational design of a chitosan-based drug delivery system. The chitosan derivative N-[(2-hydroxy-3-trimethylammonium)propyl]chitosan chloride (HTCC) was ionically cross-linked by sodium tripolyphosphate (TPP) to form sub-200-nm microgels that are responsive to pH changes. When these microgels were loaded ...

journal_title：Biomacromolecules

authors： Zhang H,Mardyani S,Chan WC,Kumacheva E

更新日期：2006-05-01 00:00:00

abstract：:Self-assembling amphiphilic designer peptides have been successfully applied as nanomaterials in biomedical applications. Understanding molecular interactions at the peptide-membrane interface is crucial, since interactions at this site often determine (in)compatibility. The present study aims to elucidate how model m...

journal_title：Biomacromolecules

authors： Kornmueller K,Lehofer B,Meindl C,Fröhlich E,Leitinger G,Amenitsch H,Prassl R

更新日期：2016-11-14 00:00:00

abstract：:The design and application of soft nanocomposite injectable hydrogels containing entrapped microgels for small-molecule drug delivery is demonstrated. Copolymer microgels based on N-isopropylacrylamide and acrylic acid were synthesized that exhibited both ionic and hydrophobic affinity for binding to bupivacaine, a ca...

journal_title：Biomacromolecules

authors： Sivakumaran D,Maitland D,Hoare T

更新日期：2011-11-14 00:00:00

abstract：:Chitosan fibers showing narrow diameter distribution with a mean of 42 nm were produced by electrospinning and utilized for the sorption of Fe(III), Cu(II), Ag(I), and Cd(II) ions from aqueous solutions. The ion concentrations in the supernatant solutions were determined using inductively coupled plasma-mass spectrome...

journal_title：Biomacromolecules

authors： Horzum N,Boyaci E,Eroğlu AE,Shahwan T,Demir MM

更新日期：2010-12-13 00:00:00

abstract：:Enzymatic ring-opening copolymerization of 5-benzyloxy-trimethylene carbonate (BTMC) and 1,4-dioxan-2-one (DON) was investigated for the first time. Immobilized porcine pancreas lipase (IPPL) on silica particles was selected to perform the copolymerization. A series of novel biodegradable copolymers with different com...

journal_title：Biomacromolecules

authors： He F,Jia HL,Liu G,Wang YP,Feng J,Zhuo RX

更新日期：2006-08-01 00:00:00

abstract：:Bacterial cellulose (BC) is a polysaccharide known as a suitable matrix for proper wound healing. To improve this ability, BC was functionalized with silk sericin (SS) that has cytoprotective and mitogenic effects. The composites obtained by solution impregnation were stabilized by hydrogen bonds, and SS could be rele...

journal_title：Biomacromolecules

authors： Lamboni L,Li Y,Liu J,Yang G

更新日期：2016-09-12 00:00:00

abstract：:Five poly(betaine) brushes were prepared, and their resistance to blood plasma fouling was studied. Two carboxybetaines monomers were copolymerized with 2-hydroxyethyl methacrylate (HEMA) to prepare novel hydrogels. By increasing the content of the zwitterionic comonomer, a 4-fold increase in the water content could b...

journal_title：Biomacromolecules

authors： Kostina NY,Rodriguez-Emmenegger C,Houska M,Brynda E,Michálek J

更新日期：2012-12-10 00:00:00