Silk Sericin-Functionalized Bacterial Cellulose as a Potential Wound-Healing Biomaterial.

abstract：:Turbidimetric titration was used to initiate associative intermolecular interactions between a pair of protein molecules, gelatin-A and gelatin-B, having complementary charges that led to pH-induced liquid-liquid phase separation and the formation of complex coacervate. The stoichiometric binding ratio was found to be...

journal_title：Biomacromolecules

authors： Tiwari A,Bindal S,Bohidar HB

更新日期：2009-01-12 00:00:00

abstract：:Their physicochemical properties and relatively low cost make cellulose nanocrystals (CNCs) a potential candidate for future large-scale production in many fields including nanomedicine. Prior to a sustained and responsible development as theranostic agents, robust and reliable data concerning their safety, biocompati...

journal_title：Biomacromolecules

authors： Colombo L,Zoia L,Violatto MB,Previdi S,Talamini L,Sitia L,Nicotra F,Orlandi M,Salmona M,Recordati C,Bigini P,La Ferla B

更新日期：2015-09-14 00:00:00

abstract：:We have studied the degradation of well-characterized soluble heteropolymeric chitosans by a novel family 46 chitosanase, ScCsn46A from Streptomyces coelicolor A3(2), to obtain insight into the enzyme's mode of action and to determine its potential for production of different chitooligosaccharides. The degradation of ...

journal_title：Biomacromolecules

authors： Heggset EB,Dybvik AI,Hoell IA,Norberg AL,Sørlie M,Eijsink VG,Vårum KM

更新日期：2010-09-13 00:00:00

abstract：:Highly fluorescent N-substituted 1-cyanobenz[f]isoindole chitosans (CBI-CSs) with various degrees of N-substitution (DS) were synthesized by reacting chitosan (CS) with naphthalene-2,3-dicarboxaldehyde (NDA) in the presence of cyanide under mild acidic conditions. Introduction of 1-cyanobenz[f]isoindole moieties into ...

journal_title：Biomacromolecules

authors： Gonil P,Sajomsang W,Ruktanonchai UR,Na Ubol P,Treetong A,Opanasopit P,Puttipipatkhachorn S

更新日期：2014-08-11 00:00:00

abstract：:Photoexcited TiO2 degrades biomolecules such as nucleic acids, cell membrane proteins, and enzymes. Stabilization of enzyme activity against the deactivation caused by the combination of TiO2-UV is essential if we are to develop novel hybrid materials exhibiting photocatalytic and biocatalytic activities useful for de...

journal_title：Biomacromolecules

authors： Lele BS,Russell AJ

更新日期：2004-09-01 00:00:00

abstract：:Cartilage tissue engineering highly relies on the ability to store and transport chondrocytes in order to be clinically successful. Cryopreservation is a most reliable technology for chondrocyte storage, but it suffers from the intrinsic toxicity of current state-of-the-art cryoprotectant, dimethyl sulfoxide (DMSO). I...

journal_title：Biomacromolecules

authors： Liu M,Zhang X,Guo H,Zhu Y,Wen C,Sui X,Yang J,Zhang L

更新日期：2019-10-14 00:00:00

abstract：:An enzymatically cross-linked polyethylene glycol (PEG)-based hydrogel was engineered to promote and align nerve cells in a three-dimensional manner. To render the injectable, otherwise bioinert, PEG-based material supportive for cell growth, its mechanical and biochemical properties were optimized. A recombinant fibr...

journal_title：Biomacromolecules

authors： Licht C,Rose JC,Anarkoli AO,Blondel D,Roccio M,Haraszti T,Gehlen DB,Hubbell JA,Lutolf MP,De Laporte L

更新日期：2019-11-11 00:00:00

abstract：:Polystyrene-polyisocyanopeptide (PS-PIAT) polymersomes containing CALB in two different locations, one in the aqueous inner compartment and one in the bilayer, were investigated for enzymatic ring-opening polymerization of lactones in water. It is shown that the monomers 8-octanolactone and dodecalactone yield oligome...

journal_title：Biomacromolecules

authors： Nallani M,de Hoog HP,Cornelissen JJ,Palmans AR,van Hest JC,Nolte RJ

更新日期：2007-12-01 00:00:00

abstract：:A simple, sequential approach for creation of hydrolytically degradable poly(ethylene glycol) (PEG) hydrogels has been developed and characterized. The chemistry involves an initial step growth polymerization reaction between PEG-diacrylate and dithiothreitol (DTT) to form acrylate-terminated (-PEG-DTT-)n PEG chains, ...

journal_title：Biomacromolecules

authors： Hudalla GA,Eng TS,Murphy WL

更新日期：2008-03-01 00:00:00

abstract：:Cardiovascular diseases plague human health because of the lack of transplantable small-diameter blood vessel (SDBV) grafts. Although expanded polytetrafluoroethylene (ePTFE) has the potential to be used as a biocompatible material for SDBV grafts, long-term patency is still the biggest challenge. As discussed in this...

journal_title：Biomacromolecules

authors： Wang D,Xu Y,Lin YJ,Yilmaz G,Zhang J,Schmidt G,Li Q,Thomson JA,Turng LS

更新日期：2020-09-14 00:00:00

abstract：:Mixed protein-based hydrogels have been prepared by blending gelatin (G) with amorphous Bombyx mori silk fibroin (SF) and promoting beta-crystallization of SF via subsequent exposure to methanol or methanol/water solutions. The introduction of beta crystals in SF serves to stabilize the hydrogel network and extend the...

journal_title：Biomacromolecules

authors： Gil ES,Frankowski DJ,Spontak RJ,Hudson SM

更新日期：2005-11-01 00:00:00

abstract：:Endo-beta-1,4-xylanases (EC 3.2.1.8) are the main enzymes involved in the hydrolysis of xylans, the most abundant hemicelluloses in plant biomass. However, the development of efficient endoxylanases for use in biorefinery processes is currently hampered by insufficient knowledge regarding the impact of the cell wall n...

journal_title：Biomacromolecules

authors： Boukari I,Putaux JL,Cathala B,Barakat A,Saake B,Rémond C,O'Donohue M,Chabbert B

更新日期：2009-09-14 00:00:00

abstract：:Cellular model systems are essential platforms used across multiple research fields for exploring the fundaments of biology and biochemistry. Here, we present giant plasma membrane vesicles (GPMVs) as a platform of cell-like compartments that will facilitate the study of particles within a biorelevant environment and ...

journal_title：Biomacromolecules

authors： Zartner L,Garni M,Craciun I,Einfalt T,Palivan CG

更新日期：2021-01-11 00:00:00

abstract：:A first attempt to attenuate the quorum sensing (QS) of a marine heterotroph microorganism, Vibrio fischeri , using signal molecule-sequestering polymers (SSPs) is presented. A set of rationally designed polymers with affinity toward a signal molecule of V. fischeri , N-(beta-ketocaproyl)-l-homoserine lactone (3-oxo-C...

journal_title：Biomacromolecules

authors： Piletska EV,Stavroulakis G,Karim K,Whitcombe MJ,Chianella I,Sharma A,Eboigbodin KE,Robinson GK,Piletsky SA

更新日期：2010-04-12 00:00:00

abstract：:Forisomes are protein polymers found in leguminous plants that have the remarkable ability to undergo reversible "muscle-like" contractions in the presence of divalent cations and in extreme pH environments. To gain insight into the molecular basis of forisome structure and assembly, we used confocal laser scanning mi...

journal_title：Biomacromolecules

authors： Groscurth S,Müller B,Schwan S,Menzel M,Diekstall F,Senft M,Kendall A,Kommor BA,Neumann U,Kalischuk M,Kawchuk LM,Krzyzanek V,Heilmann A,Stubbs G,Twyman RM,Prüfer D,Noll GA

更新日期：2012-10-08 00:00:00

abstract：:The synthesis and polymerization of six AB(3) tapered self-assembling methacrylate monomers (5a, 5b, 5c,5d, 17a, and 17b) based on first generation alkyl substituted benzyl ether monodendrons (i.e., minidendrons) containing oligooxyethylene units at their focal point and the polymerizable group on their periphery are ...

journal_title：Biomacromolecules

authors： Percec V,Bera TK

更新日期：2002-01-01 00:00:00

abstract：:The storage and transport of cells is a fundamental technology which underpins cell biology, biomaterials research, and emerging cell-based therapies. Inspired by antifreeze and ice-binding proteins in extremophiles, macromolecular (polymer) cryoprotectants are emerging as exciting biomaterials to enable the reduction...

journal_title：Biomacromolecules

authors： Murray KA,Gibson MI

更新日期：2020-07-13 00:00:00

abstract：:Photo-crosslinkable dendritic macromolecules are attractive materials for the preparation of cartilage tissue engineering scaffolds that may be optimized for in situ formation of hydrated, mechanically stable, and well-integrated hydrogel scaffolds supporting chondrocytes and chondrogenesis. We designed and synthesize...

journal_title：Biomacromolecules

authors： Söntjens SH,Nettles DL,Carnahan MA,Setton LA,Grinstaff MW

更新日期：2006-01-01 00:00:00

abstract：:Chitin nanocrystal aqueous dispersions were prepared by acid hydrolysis of crude chitin from crab shells. The resulting dispersions were studied with small deformation oscillatory experiments and polarized optical microscopy under different conditions of nanocrystal concentration, ionic strength, pH, and temperature. ...

journal_title：Biomacromolecules

authors： Tzoumaki MV,Moschakis T,Biliaderis CG

更新日期：2010-01-11 00:00:00

abstract：:This paper reports the rheological behavior of chitosan solutions that have been cross-linked with different amounts of genipin, at body temperature and physiological pH. The effect of the cross-linker loading on the rheological properties of hydrogels has been evaluated. The oscillatory time sweep method was used to ...

journal_title：Biomacromolecules

authors： Moura MJ,Figueiredo MM,Gil MH

更新日期：2007-12-01 00:00:00

abstract：:Bacterial biofilms tolerate extreme levels of antibiotics. Treatment of biofilm infections therefore requires the development of new or modified antimicrobials that can penetrate biofilms and are effective against dormant persistent cells. One such new approach uses the biodegradable biopolymer chitosan and its deriva...

journal_title：Biomacromolecules

authors： Sahariah P,Másson M,Meyer RL

更新日期：2018-09-10 00:00:00

abstract：:Human serum albumin (HSA) is known to exist as N (pH approximately 7), B (pH approximately 9), and F (pH approximately 3.5) isomeric forms and an equilibrium intermediate state (I) accumulate in the urea induced unfolding pathway of HSA around 4.8-5.2 M urea concentrations. These states displayed characteristic struct...

journal_title：Biomacromolecules

authors： Ahmad B,Parveen S,Khan RH

更新日期：2006-04-01 00:00:00

abstract：:The present study focuses on the formation of microcapsules containing catalytically active L-asparaginase (L-ASNase), a protein drug of high value in antileukemic therapy. We make use of the layer-by-layer (LbL) technique to coat protein-loaded calcium carbonate (CaCO3) particles with two or three poly dextran/poly-L...

journal_title：Biomacromolecules

authors： Karamitros CS,Yashchenok AM,Möhwald H,Skirtach AG,Konrad M

更新日期：2013-12-09 00:00:00

abstract：:Spiders have evolved a complex system of silk producing glands. Each of the glands produces silk with strength and elasticity tailored to its biological purpose. Sequence analysis of the major ampullate silk reveals four highly conserved concatenated blocks of amino acids: (GA) n , A n , GPGXX, and GGX. While the GPGX...

journal_title：Biomacromolecules

authors： Brooks AE,Stricker SM,Joshi SB,Kamerzell TJ,Middaugh CR,Lewis RV

更新日期：2008-06-01 00:00:00

abstract：:High molecular weight trimethylene carbonate (TMC) and epsilon-caprolactone (CL) (co)polymers were synthesized. Melt pressed (co)polymer films were cross-linked by gamma irradiation (25 kGy or 50 kGy) in vacuum, yielding gel fractions of up to 70%. The effects of copolymer composition and irradiation dose on the cytot...

journal_title：Biomacromolecules

authors： Bat E,Plantinga JA,Harmsen MC,van Luyn MJ,Zhang Z,Grijpma DW,Feijen J

更新日期：2008-11-01 00:00:00

abstract：:Repifermin, a truncated form of fibroblast growth factor-10 (FGF-10) also known as keratinocyte growth factor-2 (KGF-2), is a heparin-binding protein with potent regenerative properties. The protein unfolds and aggregates at relatively low temperature (~37 °C). Electrostatic interactions between polyanions and several...

journal_title：Biomacromolecules

authors： Khondee S,Olsen CM,Zeng Y,Middaugh CR,Berkland C

更新日期：2011-11-14 00:00:00

abstract：:C13-dipeptides that did not gel on their own were found to form hydrogels when combined with mixtures (coassembly). At pH = 4.6, by mixing negatively charged C13-WD (C13-WD2- and/or C13-WD-) with C13-KW or C13-YK, where the side chain of K carried positive charge, two composite hydrogels with different mechanical prop...

journal_title：Biomacromolecules

authors： Hu T,Zhang Z,Euston SR,Geng M,Pan S

更新日期：2020-12-14 00:00:00

abstract：:The development of novel reagents and antibiotics for combating multidrug resistance bacteria has received significant attention in recent years. In this study, new antimicrobial star polymers (14-26 nm in diameter) that consist of mixtures of polylysine and glycopolymer arms were developed and were shown to possess a...

journal_title：Biomacromolecules

authors： Wong EH,Khin MM,Ravikumar V,Si Z,Rice SA,Chan-Park MB

更新日期：2016-03-14 00:00:00

abstract：:We report an enzyme-based method for the in situ entrapment of cells within a biopolymeric hydrogel matrix. Specifically, we used a calcium-independent microbial transglutaminase that is known to cross-link proteins and observed that it catalyzes the formation of gels from a pre-gel solution containing 10% gelatin and...

journal_title：Biomacromolecules

authors： Chen T,Small DA,McDermott MK,Bentley WE,Payne GF

更新日期：2003-11-01 00:00:00

abstract：:Poly(3-hydroxybutyrate) (PHB) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) are biopolyesters reported to provide favorable microenvironments for cell culture and possess potential for tissue engineering applications. Both biopolymers have been investigated for applications in a variety of medical scenarios,...

journal_title：Biomacromolecules

authors： Ahmed T,Marçal H,Lawless M,Wanandy NS,Chiu A,Foster LJ

更新日期：2010-10-11 00:00:00