Abstract：
:High internal phase emulsion (HIPE)-templating is an attractive method of producing high porosity polymer foams with tailored pore structure, pore size and porosity. However, this method typically requires the use of large amounts of surfactants to stabilize the immiscible liquid phases, and polymerizable monomers/cross-linker in the continuous minority phase to solidify the HIPE, which may not be desirable in many applications. We show that polyHIPEs with a porosity of 73% can be formed solely using a copolymer of chitosan-graft-PNIPAM-graft-oligoproline (CSN-PRO), which acts simultaneously as emulsifier and thermoresponsive gelator, and forms upon removal of the liquid templating phases, the bulk structure of the resulting polyHIPE. With only a small amount of surfactant (1%v/v in the aqueous phase), and varying the polymer concentration and internal phase volume ratio, different polyHIPEs with porosities of up to 99%, surface areas in excess of 300 m(2)/g and controlled pore interconnectivity can be formed. The poly(CSN-PRO)HIPEs are also shown to be thermoresponsive and remained intact when immersed into water above 34 °C but dissolve below their LCST, which is useful for applications such as drug delivery and tissue engineering scaffolds.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Oh BH,Bismarck A,Chan-Park MBdoi
10.1021/bm500172usubject
Has Abstractpub_date
2014-05-12 00:00:00pages
1777-87issue
5eissn
1525-7797issn
1526-4602journal_volume
15pub_type
杂志文章abstract：:An injectable, heparin-based hydrogel system with the potential to be gelled with cells was developed. First, heparin was modified to have thiol groups by the modification of carboxylic groups of heparin with cysteamine using carbodiimide chemistry. Thiol functionalization of heparin carboxylic groups was controlled f...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm0701189
更新日期：2007-06-01 00:00:00
abstract：:Tiopronin (N-(2-mercaptopropionyl)glycine)-protected gold nanoparticles (TPAu) were cross-linked to collagen via EDC (1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide) coupling. On average, each TPAu forms eight amide bonds with collagen lysine moieties. The resulting gels were studied with environmental SEM, TEM, micr...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm800793z
更新日期：2008-12-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.7b01063
更新日期：2017-12-11 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm2017146
更新日期：2012-05-14 00:00:00
abstract：:Chitosan fibers showing narrow diameter distribution with a mean of 42 nm were produced by electrospinning and utilized for the sorption of Fe(III), Cu(II), Ag(I), and Cd(II) ions from aqueous solutions. The ion concentrations in the supernatant solutions were determined using inductively coupled plasma-mass spectrome...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm100755x
更新日期：2010-12-13 00:00:00
abstract：:Poloxamer thermoresponsive gels are widely explored in controlled drug delivery. Nevertheless, these gels possess inadequate mechanical properties, poor bioadhesiveness, and high permeability to water. To overcome these issues, we blended mucoadhesive hyaluronic acid (HA) with poloxamer analogs. This study aimed to in...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm1008958
更新日期：2011-01-10 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm700481h
更新日期：2007-09-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.7b00229
更新日期：2017-05-08 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm301125g
更新日期：2012-11-12 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm101230n
更新日期：2011-03-14 00:00:00
abstract：:This study presents an efficient and systematic approach to synthesize bioapplicable porous hollow polymeric capsules (HPCs). The hydroxyl-functionalized nanoporous polymers with hollow capsular shapes could be generated via the moderate Friedel-Crafts reaction without using any hard or soft template. The numerous pri...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.0c01520
更新日期：2020-12-17 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm8001717
更新日期：2008-07-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.5b01578
更新日期：2016-03-14 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm800252c
更新日期：2008-07-01 00:00:00
abstract：:The storage and transport of cells is a fundamental technology which underpins cell biology, biomaterials research, and emerging cell-based therapies. Inspired by antifreeze and ice-binding proteins in extremophiles, macromolecular (polymer) cryoprotectants are emerging as exciting biomaterials to enable the reduction...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.0c00591
更新日期：2020-07-13 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.9b01266
更新日期：2019-12-09 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.9b01141
更新日期：2020-01-13 00:00:00
abstract：:We report here the first evidence for the interaction of poly(ethylene glycol) (PEG) with hyaluronan (HA) in aqueous solutions. PEG-HA complexes (Kapp = 45,000 ± 8000 M-1) contained about 3.3 ± 0.1 of ethylene glycol units per disaccharide of HA. The carboxyl of the D-glucuronic acid and the amide of the N-acetyl-D-gl...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.0c01504
更新日期：2020-12-16 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm0506952
更新日期：2006-03-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm1013525
更新日期：2011-03-14 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm900958c
更新日期：2010-01-11 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm401309u
更新日期：2014-01-13 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm300399s
更新日期：2012-05-14 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm060930w
更新日期：2007-03-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.6b00906
更新日期：2016-08-08 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm0200231
更新日期：2002-09-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.6b01831
更新日期：2017-03-13 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm400354y
更新日期：2013-07-08 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm700690p
更新日期：2007-11-01 00:00:00
abstract：:As with many other biosourced colloids, chitin nanocrystals (ChNCs) can form liquid crystalline phases with chiral nematic ordering. In this work, we demonstrate that it is possible to finely tune the liquid crystalline behavior of aqueous ChNC suspensions finely. Such control was made possible by carefully studying h...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.9b00589
更新日期：2019-07-08 00:00:00
