Unraveling the Correlations between Conformation, Lubrication, and Chemical Stability of Bottlebrush Polymers at Interfaces.

abstract：:A novel aptamer modified thermosensitive liposome was designed as an efficient magnetic resonance imaging probe. In this paper, Gd-DTPA was encapsulated into an optimized thermosensitive liposome (TSL) formulation, followed by conjugation with AS1411 for specific targeting against tumor cells that overexpress nucleoli...

journal_title：Biomacromolecules

authors： Zhang K,Liu M,Tong X,Sun N,Zhou L,Cao Y,Wang J,Zhang H,Pei R

更新日期：2015-09-14 00:00:00

abstract：:Properties of Aloe vera galacturonate hydrogels formed via Ca(2+) crosslinking have been studied in regard to key parameters influencing gel formation including molecular weight, ionic strength, and molar ratio of Ca(2+) to COO(-) functionality. Dynamic oscillatory rheology and pulsed field gradient NMR (PFG-NMR) stud...

journal_title：Biomacromolecules

authors： McConaughy SD,Kirkland SE,Treat NJ,Stroud PA,McCormick CL

更新日期：2008-11-01 00:00:00

abstract：:Amphiphilic glycopolymers, polylactide-grafted dextran copolymers (Dex-g-PLA), were synthesized with a well-controlled architecture obtained through a three-step procedure: partial silylation of the dextran hydroxyl groups, ring-opening polymerization of D,L-lactide initiated from remaining hydroxyl groups, silylether...

journal_title：Biomacromolecules

authors： Raynaud J,Choquenet B,Marie E,Dellacherie E,Nouvel C,Six JL,Durand A

更新日期：2008-03-01 00:00:00

abstract：:Inspired by tea stains, plant polyphenolic tannic acid (TA) was beneficially employed as the primer anchor for functional polymer brushes. The brominated TA (TABr) initiator primer was synthesized by partial modification of TA with alkyl bromide functionalities. TABr with trihydroxyphenyl moieties can readily anchor o...

journal_title：Biomacromolecules

authors： Pranantyo D,Xu LQ,Neoh KG,Kang ET,Ng YX,Teo SL

更新日期：2015-03-09 00:00:00

abstract：:Herein we present an innovative approach to produce biocompatible, degradable, and stealth polymeric nanoparticles based on poly(lipoic acid), stabilized by a PEG-ended surfactant. Taking advantage of the well-known thiol-induced polymerization of lipoic acid, a universal and nontoxic nanovector consisted of a solid c...

journal_title：Biomacromolecules

authors： Trzciński JW,Morillas-Becerril L,Scarpa S,Tannorella M,Muraca F,Rastrelli F,Castellani C,Fedrigo M,Angelini A,Tavano R,Papini E,Mancin F

更新日期：2020-12-21 00:00:00

abstract：:Two poly(amido-amine)s (oligoPAM and oligoNER) containing bis-phosphonate residues were obtained by a Michael-type polyaddition of pamidronate and neridronate to 1,4-bis(acryloyl)piperazine. The SEC (size-exclusion chromatography) and the MALDI-TOF (matrix assisted laser desorption ionization) analyses were consistent...

journal_title：Biomacromolecules

authors： Casolaro M,Casolaro I,Spreafico A,Capperucci C,Frediani B,Marcolongo R,Margiotta N,Ostuni R,Mendichi R,Samperi F,Ishii T,Ito Y

更新日期：2006-12-01 00:00:00

abstract：:The application of nanoparticles comprising amphiphilic block copolymers for the delivery of drugs is a subject of great interest as they hold promise for more effective and selective therapies. In order to achieve this ambition, it is of critical importance to develop our understanding of the self-assembly mechanisms...

journal_title：Biomacromolecules

authors： Ridolfo R,Arends JJ,van Hest JCM,Williams DS

更新日期：2020-06-08 00:00:00

abstract：:In the fields of surgery and regenerative medicine, it is crucial to understand the interactions of proteins with the biomaterials used as implants. Protein adsorption directly influences cell-material interactions in vivo and, as a result, regulates, for example, cell adhesion on the surface of the implant. Therefore...

journal_title：Biomacromolecules

authors： Schönwälder SM,Bally F,Heinke L,Azucena C,Bulut ÖD,Heißler S,Kirschhöfer F,Gebauer TP,Neffe AT,Lendlein A,Brenner-Weiß G,Lahann J,Welle A,Overhage J,Wöll C

更新日期：2014-07-14 00:00:00

abstract：:An efficient process for the synthesis of degradable hydrogels containing octa-betaine ester polyhedral oligomeric silsesquioxane (POSS) through efficient thiol-ene and Menschutkin click reactions was developed. The hydrogels exhibited a yield strength of 0.36 MPa and a compressive modulus of 4.38 MPa and displayed ex...

journal_title：Biomacromolecules

authors： Han J,Chen Q,Shen Y,Liu Z,Hao X,Zhong M,Zhao Z,Bockstaller MR

更新日期：2020-09-14 00:00:00

abstract：:Enzymatic adsorption and degradation of three types of aliphatic polyester films and two types of polyolefin films by the extracellular PHB depolymerase from Alcaligenes faecalis T1 have been studied by using a quartz crystal microbalance (QCM) technique. Hydrolysis of poly[(R)-3-hydroxybutyrate] was quantitatively fo...

journal_title：Biomacromolecules

authors： Yamashita K,Aoyagi Y,Abe H,Doi Y

更新日期：2001-04-01 00:00:00

abstract：:There is a distinct need for antimicrobial compounds that can act at surfaces without leaching into the environment. Such materials should be easy to synthesize, be easy to apply to surfaces, and display reasonable levels of antimicrobial and antifungal activity. Here we describe such a surface-active compound and dem...

journal_title：Biomacromolecules

authors： Ravikumar T,Murata H,Koepsel RR,Russell AJ

更新日期：2006-10-01 00:00:00

abstract：:Magnetosomes are natural magnetic nanoparticles with exceptional properties that are synthesized in magnetotactic bacteria by a highly regulated biomineralization process. Their usability in many applications could be further improved by encapsulation in biocompatible polymers. In this study, we explored the productio...

journal_title：Biomacromolecules

authors： Mickoleit F,Borkner CB,Toro-Nahuelpan M,Herold HM,Maier DS,Plitzko JM,Scheibel T,Schüler D

更新日期：2018-03-12 00:00:00

abstract：:An underwater bioadhesive generally comprises a multiprotein complex that provides a molecular basis for self-assembly. We report here a new class of self-assembling peptide inspired by a 20 kDa barnacle cement protein. Studies on the chemically synthesized 24-residue peptide have revealed that (1) it underwent irreve...

journal_title：Biomacromolecules

authors： Nakano M,Shen JR,Kamino K

更新日期：2007-06-01 00:00:00

abstract：:Five poly(betaine) brushes were prepared, and their resistance to blood plasma fouling was studied. Two carboxybetaines monomers were copolymerized with 2-hydroxyethyl methacrylate (HEMA) to prepare novel hydrogels. By increasing the content of the zwitterionic comonomer, a 4-fold increase in the water content could b...

journal_title：Biomacromolecules

authors： Kostina NY,Rodriguez-Emmenegger C,Houska M,Brynda E,Michálek J

更新日期：2012-12-10 00:00:00

abstract：:Water-soluble, degradable polymers based on poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) with low cytotoxicity and good p-DNA transfection efficiency are highlighted in this article. To solve the nondegradability issue of PDMAEMA, new polymers based on DMAEMA and 5,6-benzo-2-methylene-1,3-dioxepane (BMDO) for g...

journal_title：Biomacromolecules

authors： Zhang Y,Zheng M,Kissel T,Agarwal S

更新日期：2012-02-13 00:00:00

abstract：:A wood based yarn platform for capturing pharmaceutical molecules from water was developed. Cellulose fiber yarns were modified with cyclodextrins, and the capture of 17α-ethinyl estradiol (EE2), a synthetic estrogen hormone used as contraceptive, from water was tested. The yarns were prepared by spinning a deep eutec...

journal_title：Biomacromolecules

authors： Orelma H,Virtanen T,Spoljaric S,Lehmonen J,Seppälä J,Rojas OJ,Harlin A

更新日期：2018-02-12 00:00:00

abstract：:A major challenge in drug delivery is the internalization through the apical plasma membrane of the polarized epithelial cells lining organs facing the external environment, e.g., lungs and the gastrointestinal tract. The reduced permeation of drugs entering through this pathway is in part due to the mucosal barrier a...

journal_title：Biomacromolecules

authors： Harush-Frenkel O,Rozentur E,Benita S,Altschuler Y

更新日期：2008-02-01 00:00:00

abstract：:Multifunctional and highly biocompatible polyether structures play a key role in shielding liposomes from degradation in the bloodstream, providing also multiple functional groups for further attachment of targeting moieties. In this work hyperbranched polyglycerol ( hbPG) bearing lipids with long alkyl chain anchor a...

journal_title：Biomacromolecules

authors： Wagener K,Worm M,Pektor S,Schinnerer M,Thiermann R,Miederer M,Frey H,Rösch F

更新日期：2018-07-09 00:00:00

abstract：:We studied methoxy poly(ethylene glycol)-b-poly(ε-caprolactone)-b-poly(2-dimethylaminoethyl methacrylate) (mPEG-b-PCL-b-PDMAEMA) nanoparticles as the codelivery vector of hydrophobic drug and pDNA by employing dynamic light scattering (DLS), ζ potential, transmission electron microscopy (TEM), gel retardation assay, a...

journal_title：Biomacromolecules

authors： Yue X,Qiao Y,Qiao N,Guo S,Xing J,Deng L,Xu J,Dong A

更新日期：2010-09-13 00:00:00

abstract：:The adsorption of human immunoglobulin G (hIgG) and bovine serum albumin (BSA) on cellulose supports were investigated. The dynamics and extent of related adsorption processes were monitored by surface plasmon resonance (SPR) and quartz crystal microbalance with dissipation monitoring (QCM-D). Amine groups were instal...

journal_title：Biomacromolecules

authors： Orelma H,Filpponen I,Johansson LS,Laine J,Rojas OJ

更新日期：2011-12-12 00:00:00

abstract：:Exendin-4 (EX4), a glucagon-like peptide-1 receptor (GLP-1R) agonist that regulates blood glucose levels, has been used in the management of type-2 diabetes mellitus. EX4 can be PEGylated to improve its antidiabetic effects by enhancing its stability and extending the circulation half-life. Here, to determine whether ...

journal_title：Biomacromolecules

authors： Lee W,Park EJ,Kwak S,Lee KC,Na DH,Bae JS

更新日期：2016-03-14 00:00:00

abstract：:The massive use of antibiotics in healthcare and agriculture has led to their artificial accumulation in natural habitats, which risks the structure and function of the microbial communities in ecosystems, threatens food and water security, and accelerates the development of resistome. Ideally, antibiotics should rema...

journal_title：Biomacromolecules

authors： Zheng W,Anzaldua M,Arora A,Jiang Y,McIntyre K,Doerfert M,Winter T,Mishra A,Ma H,Liang H

更新日期：2020-06-08 00:00:00

abstract：:Many dental restorative dental composites still utilize 2,2-bis[4-(2-hydroxy-3-methacryloyloxy propoxy) phenyl] propane (Bis-GMA) as base resin. The high viscosity of Bis-GMA necessitates dilution with dimethacrylate ethers of low viscosity such as triethylene glycol dimethacrylate (TEGDMA). However, increased amounts...

journal_title：Biomacromolecules

authors： Kim JW,Kim LU,Kim CK,Cho BH,Kim OY

更新日期：2006-01-01 00:00:00

abstract：:Vaginal films featuring the pH-dependent release of tenofovir (TFV) were developed for the prevention of sexual transmission of human immunodeficiency syndrome (HIV). Films based on hydroxypropyl methylcellulose and zein were prepared incorporating different plasticizers [oleic acid, lactic acid, glycerol, and polyeth...

journal_title：Biomacromolecules

authors： Notario-Pérez F,Cazorla-Luna R,Martín-Illana A,Galante J,Ruiz-Caro R,Sarmento B,das Neves J,Veiga MD

更新日期：2021-01-06 00:00:00

abstract：:A series of copolymers of trimethylene carbonate (TMC) and L-lactide (LLA) were synthesized and evaluated as scaffolds for the production of artificial blood vessels. The polymers were end-functionalized with acrylate, cast into films, and cross-linked using UV light. The mechanical, degradation, and biocompatibility ...

journal_title：Biomacromolecules

authors： Dargaville BL,Vaquette C,Peng H,Rasoul F,Chau YQ,Cooper-White JJ,Campbell JH,Whittaker AK

更新日期：2011-11-14 00:00:00

abstract：:Textile chitosan fiber scaffolds were developed and tested in terms of biocompatibility for human bone marrow stromal cells (hBMSCs). A part of the scaffolds was further modified by coating with fibrillar collagen type I in order to biologize the surface. hBMSCs of two donors were used for cell culture experiments in ...

journal_title：Biomacromolecules

authors： Heinemann C,Heinemann S,Lode A,Bernhardt A,Worch H,Hanke T

更新日期：2009-05-11 00:00:00

abstract：:Silk fibroin hydrogels with tunable properties could be obtained from aqueous fibroin solutions (4.2 w/v %) in a short period of time. This was achieved by the addition of ethylene glycol diglycidyl ether (EGDE) into the reaction solution. Introduction of EGDE cross-links between the fibroin molecules decreases the mo...

journal_title：Biomacromolecules

authors： Karakutuk I,Ak F,Okay O

更新日期：2012-04-09 00:00:00

abstract：:Biomimetic nanocomposites and scaffolds hold the key to a wide range of biomedical applications. Here we show, for the first time, a facile scheme of cofibrillizing pathogenic and functional amyloid fibrils via gold nanoparticles (AuNPs) and their applications against amyloidogenesis. This scheme was realized by β-she...

journal_title：Biomacromolecules

authors： Javed I,Sun Y,Adamcik J,Wang B,Kakinen A,Pilkington EH,Ding F,Mezzenga R,Davis TP,Ke PC

更新日期：2017-12-11 00:00:00

abstract：:Disulfide bonds stabilize the tertiary- and quaternary structure of proteins. In addition, they can be used to engineer redox-sensitive (bio)materials and drug-delivery systems. Many of these applications require control of the stability of the disulfide bond. It has recently been shown that the charged microenvironme...

journal_title：Biomacromolecules

authors： Wu C,Wang S,Brülisauer L,Leroux JC,Gauthier MA

更新日期：2013-07-08 00:00:00

abstract：:A challenge in the development of multifunctional drug delivery systems is to establish a reasonable and effective synthetic route for multifunctional polymer preparation. Herein, we propose a unique protocol to prepare multifunctional micelles by a cross-assembly process using three different functional polyurethanes...

journal_title：Biomacromolecules

authors： Pan Z,Ren Y,Song N,Song Y,Li J,He X,Luo F,Tan H,Fu Q

更新日期：2016-06-13 00:00:00