Self-Assembled Peptide-Carbon Nitride Hydrogel as a Light-Responsive Scaffold Material.

abstract：:Cellular model systems are essential platforms used across multiple research fields for exploring the fundaments of biology and biochemistry. Here, we present giant plasma membrane vesicles (GPMVs) as a platform of cell-like compartments that will facilitate the study of particles within a biorelevant environment and ...

journal_title：Biomacromolecules

authors： Zartner L,Garni M,Craciun I,Einfalt T,Palivan CG

更新日期：2021-01-11 00:00:00

abstract：:Inorganic polyphosphates, linear polymers of orthophosphate, occur naturally throughout biology and have many industrial applications. Their biodegradable nature makes them attractive for a multitude of uses, and it would be important to understand how polyphosphates are turned over enzymatically. Studies of inorganic...

journal_title：Biomacromolecules

authors： Hebbard CF,Wang Y,Baker CJ,Morrissey JH

更新日期：2014-08-11 00:00:00

abstract：:Alginate-based amphiphilic graft copolymers were synthesized by single electron transfer living radical polymerization (SET-LRP), forming stable micelles during polymerization induced self-assembly (PISA). First, alginate macroinitiator was prepared by partial depolymerization of native alginate, solubility modificati...

journal_title：Biomacromolecules

authors： Kapishon V,Whitney RA,Champagne P,Cunningham MF,Neufeld RJ

更新日期：2015-07-13 00:00:00

abstract：:Hydrogels with pH-sensitive poly(acrylic acid) (PAAc) chains and biodegradable acryloyl-poly(-caprolactone)-2-hydroxylethyl methacrylate (AC-PCL-HEMA) chains were designed and synthesized. The morphology of hydrogel was observed by scanning electron microscopy. The degradation of the hydrogel in the presence of Pseudo...

journal_title：Biomacromolecules

authors： Wu DQ,Sun YX,Xu XD,Cheng SX,Zhang XZ,Zhuo RX

更新日期：2008-04-01 00:00:00

abstract：:Nitrilotriacetic amine (NTA)-functionalized nanoparticles obtained by aqueous polymerization-induced self-assembly (PISA) are introduced as immobilization supports for polyhistidine-functionalized (His-tagged) enzymes. A novel initiator for nitroxide-mediated polymerization based on the nitroxide SG1 and carrying a pr...

journal_title：Biomacromolecules

authors： Keller D,Beloqui A,Martínez-Martínez M,Ferrer M,Delaittre G

更新日期：2017-09-11 00:00:00

abstract：:Highly fluorescent N-substituted 1-cyanobenz[f]isoindole chitosans (CBI-CSs) with various degrees of N-substitution (DS) were synthesized by reacting chitosan (CS) with naphthalene-2,3-dicarboxaldehyde (NDA) in the presence of cyanide under mild acidic conditions. Introduction of 1-cyanobenz[f]isoindole moieties into ...

journal_title：Biomacromolecules

authors： Gonil P,Sajomsang W,Ruktanonchai UR,Na Ubol P,Treetong A,Opanasopit P,Puttipipatkhachorn S

更新日期：2014-08-11 00:00:00

abstract：:A dual-targeted siRNA nanocarrier has been synthesized and validated that is selectively activated in environments where there is colocalization of two breast cancer hallmarks, elevated matrix metalloproteinase (MMP) activity and folate receptor overexpression. This siRNA nanocarrier is self-assembled from two polymer...

journal_title：Biomacromolecules

authors： Li H,Miteva M,Kirkbride KC,Cheng MJ,Nelson CE,Simpson EM,Gupta MK,Duvall CL,Giorgio TD

更新日期：2015-01-12 00:00:00

abstract：:Recent findings suggest that visible light-promoted photooxidative processes mediated by sensitizers of appropriate chemical structure could represent a useful tool for properly addressing the problem of the increasing occurrence of infectious diseases caused by multiantibiotic-resistant microbial pathogens. The monoc...

journal_title：Biomacromolecules

authors： Ferro S,Jori G,Sortino S,Stancanelli R,Nikolov P,Tognon G,Ricchelli F,Mazzaglia A

更新日期：2009-09-14 00:00:00

abstract：:It is an important challenge for bone repair to effectively deliver growth factors and at the same time to prevent and cure inflammation without obvious pathogen resistance. We designed a kind of antibacterial peptide-mimetic alternating copolymers (PMACs) to effectively inhibit and kill both Gram-positive and Gram-ne...

journal_title：Biomacromolecules

authors： Zhou C,Yuan Y,Zhou P,Wang F,Hong Y,Wang N,Xu S,Du J

更新日期：2017-12-11 00:00:00

abstract：:The thermally induced aggregation of bovine β-lactoglobulin in the glass state was studied both as the pure protein and in trehalose mixtures. Calorimetric measurements and size exclusion chromatography were used to characterize the glass state and aggregation, respectively. The initial aggregation rate was characteri...

journal_title：Biomacromolecules

authors： Pérez-Moral N,Adnet C,Noel TR,Parker R

更新日期：2010-11-08 00:00:00

abstract：:The development of polymers that are both bactericidal and biocompatible would have many applications and are currently of research interest. Following the development of strongly bactericidal copolymers of 4-vinylpyridine and poly(ethylene glycol) methyl ether methacrylate, biocompatibility assays have been completed...

journal_title：Biomacromolecules

authors： Stratton TR,Howarter JA,Allison BC,Applegate BM,Youngblood JP

更新日期：2010-05-10 00:00:00

abstract：:The mechanical and melt flow properties of two thermoplastic potato starch materials with different amylose contents were evaluated. The materials were prepared by mixing starch, glycerol, and water, mainly in the weight proportions of 10:3:4.5. Compression molding was used to produce sheets/films with a thickness in ...

journal_title：Biomacromolecules

authors： Thunwall M,Boldizar A,Rigdahl M

更新日期：2006-03-01 00:00:00

abstract：:An increase in hyaluronan (HA) synthesis, cellular uptake, and metabolism occurs during the remodeling of tissue microenvironments following injury and during disease processes such as cancer. We hypothesized that multimodality HA-based probes selectively target and detectably accumulate at sites of high HA metabolism...

journal_title：Biomacromolecules

authors： Veiseh M,Breadner D,Ma J,Akentieva N,Savani RC,Harrison R,Mikilus D,Collis L,Gustafson S,Lee TY,Koropatnick J,Luyt LG,Bissell MJ,Turley EA

更新日期：2012-01-09 00:00:00

abstract：:The lack of selectivity and low solubility of many chemotherapeutics impels the development of different biocompatible nanosized drug carriers. Amphiphilic block copolymers, composed of a hydrophilic and hydrophobic domain, show great potential because of their small size, large solubilizing power and loading capacity...

journal_title：Biomacromolecules

authors： Kasmi S,Louage B,Nuhn L,Van Driessche A,Van Deun J,Karalic I,Risseeuw M,Van Calenbergh S,Hoogenboom R,De Rycke R,De Wever O,Hennink WE,De Geest BG

更新日期：2016-01-11 00:00:00

abstract：:A polyethylene glycol (PEG) retinylamine (Ret-NH2) conjugate PEG-GFL-NH-Ret with a glycine-phenylalanine-leucine (GFL) spacer was synthesized for controlled oral delivery of Ret-NH2 to treat retinal degenerative diseases, including Stargardt disease (STGD) and age-related macular degeneration (AMD). The peptide spacer...

journal_title：Biomacromolecules

authors： Yu G,Wu X,Ayat N,Maeda A,Gao SQ,Golczak M,Palczewski K,Lu ZR

更新日期：2014-12-08 00:00:00

abstract：:Cell cultivation on the surface of a novel poly(N-isopropylacrylamide) (PNIPA) hydrogel (N-NC gel), consisting of a specific type of organic (PNIPA)/inorganic (clay) network, was studied using three cell types; HepG2 human hepatoma cells, human dermal fibroblasts, and human umbilical vein endothelial cells. For the fi...

journal_title：Biomacromolecules

authors： Haraguchi K,Takehisa T,Ebato M

更新日期：2006-11-01 00:00:00

abstract：:The ability to adopt at least two different stable conformations is a common feature of proteins involved in many neurodegenerative diseases. The involved molecules undergo a conformational transition from native, mainly helical states to insoluble amyloid structures that have high β-sheet content. A detailed characte...

journal_title：Biomacromolecules

authors： Gerling UI,Brandenburg E,von Berlepsch H,Pagel K,Koksch B

更新日期：2011-08-08 00:00:00

abstract：:AQ-Pal14 is a 30-residue polypeptide that was designed to form an α-helical coiled coil that contains a metal-binding 4-pyridylalanine residue on its solvent-exposed surface. However, characterization of this peptide shows that it exists as a three-stranded coiled coil, not a two-stranded one as predicted from its des...

journal_title：Biomacromolecules

authors： Zaytsev DV,Xie F,Mukherjee M,Bludin A,Demeler B,Breece RM,Tierney DL,Ogawa MY

更新日期：2010-10-11 00:00:00

abstract：:Our previous studies have demonstrated the efficacy of generation 5 poly(amidoamine) dendrimers (G5-PAMAM) as a platform for the targeted delivery of chemotherapeutics. However, anticancer therapy can be subverted by anti-apoptotic changes in cancer cells. Bcl-2 and several of its peptides are commonly overexpressed i...

journal_title：Biomacromolecules

authors： Myc A,Patri AK,Baker JR Jr

更新日期：2007-10-01 00:00:00

abstract：:In this work, biodegradable branched polycationic polymers were synthesized by Michael addition polymerization from different amine monomers and the triacrylate monomer trimethylolpropane triacrylate. The polymers varied in the number of amines that dissociate in different pH ranges, which are considered to be benefic...

journal_title：Biomacromolecules

authors： Chew SA,Hacker MC,Saraf A,Raphael RM,Kasper FK,Mikos AG

更新日期：2010-03-08 00:00:00

abstract：:This study is devoted to developing amphiphilic block polymers based on phenylborate ester, which can self-assemble to form nanoparticles, as a glucose-sensitive drug carrier. Poly(ethylene glycol)-block-poly[(2-phenylboronic esters-1,3-dioxane-5-ethyl) methylacrylate] (MPEG5000-block-PBDEMA) was fabricated with MPEG5...

journal_title：Biomacromolecules

authors： Yao Y,Zhao L,Yang J,Yang J

更新日期：2012-06-11 00:00:00

abstract：:Spider dragline silk exhibits an extraordinary toughness and is typically composed of two types of major ampullate spidroins (MaSp1 and MaSp2), differing in their proline content and hydrophobicity. In this paper, we recombinantly produced an unusual but naturally occurring short major ampullate spidroin (MaSp1s) as a...

journal_title：Biomacromolecules

authors： Thamm C,Scheibel T

更新日期：2017-04-10 00:00:00

abstract：:Silk fibroin hydrogels with tunable properties could be obtained from aqueous fibroin solutions (4.2 w/v %) in a short period of time. This was achieved by the addition of ethylene glycol diglycidyl ether (EGDE) into the reaction solution. Introduction of EGDE cross-links between the fibroin molecules decreases the mo...

journal_title：Biomacromolecules

authors： Karakutuk I,Ak F,Okay O

更新日期：2012-04-09 00:00:00

abstract：:Super-resolution fluorescence microscopy, specifically stochastic reconstruction microscopy (STORM), and atomic force microscopy (AFM) were used to image the self-assembly processes of the peptide surfactant I3K. The peptide surfactants self-assembled into giant helical fibrils with diameters between 5 and 10 nm with ...

journal_title：Biomacromolecules

authors： Cox H,Georgiades P,Xu H,Waigh TA,Lu JR

更新日期：2017-11-13 00:00:00

abstract：:Heparin, a sulfated polysaccharide derived from animal sources, is the most commonly used parenteral anticoagulant drug, but it suffers from significant safety and supply issues. Herein, we describe the preparation of heparin mimetic homo- and copolymers via the reversible addition-fragmentation chain transfer (RAFT) ...

journal_title：Biomacromolecules

authors： Nahain AA,Ignjatovic V,Monagle P,Tsanaktsidis J,Vamvounis G,Ferro V

更新日期：2020-02-10 00:00:00

abstract：:We investigate the effects of mixing a colloidal suspension of tunicate-derived cellulose nanocrystals (t-CNCs) with aqueous colloidal suspensions of two protein diblock copolymers, EC and CE, which bear two different self-assembling domains (SADs) derived from elastin (E) and the coiled-coil region of cartilage oligo...

journal_title：Biomacromolecules

authors： Haghpanah JS,Tu R,Da Silva S,Yan D,Mueller S,Weder C,Foster EJ,Sacui I,Gilman JW,Montclare JK

更新日期：2013-12-09 00:00:00

abstract：:The remarkable diversity of the self-assembly behavior of PEG-peptides is reviewed, including self-assemblies formed by PEG-peptides with β-sheet and α-helical (coiled-coil) peptide sequences. The modes of self-assembly in solution and in the solid state are discussed. Additionally, applications in bionanotechnology a...

journal_title：Biomacromolecules

authors： Hamley IW

更新日期：2014-05-12 00:00:00

abstract：:Dextrin, a glucose polymer with low molecular weight, was used to develop a fully resorbable hydrogel, without using chemical initiators. Dextrin was first oxidized (oDex) with sodium periodate and then cross-linked with adipic acid dihidrazide, a nontoxic cross-linking molecule. Furthermore, a new bidimensional compo...

journal_title：Biomacromolecules

authors： Molinos M,Carvalho V,Silva DM,Gama FM

更新日期：2012-02-13 00:00:00

abstract：:Electrically conductive hydrogel composites consisting of oligo(polyethylene glycol) fumarate (OPF) and polypyrrole (PPy) were developed for applications in nerve regeneration. OPF-PPy scaffolds were synthesized using three different anions: naphthalene-2-sulfonic acid sodium salt (NSA), dodecylbenzenesulfonic acid so...

journal_title：Biomacromolecules

authors： Runge MB,Dadsetan M,Baltrusaitis J,Ruesink T,Lu L,Windebank AJ,Yaszemski MJ

更新日期：2010-11-08 00:00:00

abstract：:Double-network (DN) hydrogels are fabricated from poly(2-ethyl-2-oxazoline) (PEOXA)-peptide conjugates, which can be enzymatically crosslinked in the presence of Sortase A (SA), and physical networks of alginate (Alg), yielding matrices with improved mechanical properties with respect to the corresponding PEOXA and Al...

journal_title：Biomacromolecules

authors： Trachsel L,Johnbosco C,Lang T,Benetti EM,Zenobi-Wong M

更新日期：2019-12-09 00:00:00