Abstract：
:The development of polymers that are both bactericidal and biocompatible would have many applications and are currently of research interest. Following the development of strongly bactericidal copolymers of 4-vinylpyridine and poly(ethylene glycol) methyl ether methacrylate, biocompatibility assays have been completed on these materials to measure their potential biocompatibility. In this article, a new methodology for measuring protein interaction was developed for water-soluble polymers by coupling proteins to surfaces and then measuring the adsorption of copolymers onto these surfaces. Ellipsometry was then used to measure the thickness of adsorbed polymers as a measurement of biocompatibility. These results were then compared and correlated with the results of other biocompatibility assays previously conducted on these polymers, affording a greater understanding of the biocompatibility of the copolymers as well as improving the understanding of the effect of hydrophilic and hydrophobic groups that is vital for the development of these materials.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Stratton TR,Howarter JA,Allison BC,Applegate BM,Youngblood JPdoi
10.1021/bm1000839subject
Has Abstractpub_date
2010-05-10 00:00:00pages
1286-90issue
5eissn
1525-7797issn
1526-4602journal_volume
11pub_type
杂志文章abstract：:Fluorescence and circular dichroism spectroscopy were used to monitor the conformational transition of regenerated Bombyx mori silk fibroin (RSF) in aqueous solutions under different conditions. According to the analysis of fluorescence spectra using anilinonaphthalene-8-sulfonic acid magnesium salt (ANS) as an extern...
journal_title：Biomacromolecules
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journal_title：Biomacromolecules
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更新日期：2008-09-01 00:00:00
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journal_title：Biomacromolecules
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更新日期：2004-07-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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journal_title：Biomacromolecules
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm0607776
更新日期：2007-01-01 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2005-09-01 00:00:00
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journal_title：Biomacromolecules
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更新日期：2015-03-09 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2020-12-14 00:00:00
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pub_type： 杂志文章
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更新日期：2010-12-13 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm7014152
更新日期：2008-04-01 00:00:00
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journal_title：Biomacromolecules
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更新日期：2017-12-11 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm300363g
更新日期：2012-06-11 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm0609691
更新日期：2007-05-01 00:00:00
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更新日期：2011-03-14 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2017-06-12 00:00:00
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journal_title：Biomacromolecules
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doi：10.1021/bm060144r
更新日期：2006-09-01 00:00:00
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更新日期：2009-01-12 00:00:00
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journal_title：Biomacromolecules
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journal_title：Biomacromolecules
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更新日期：2012-08-13 00:00:00
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journal_title：Biomacromolecules
pub_type： 杂志文章
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更新日期：2017-10-09 00:00:00
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更新日期：2009-09-14 00:00:00
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journal_title：Biomacromolecules
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更新日期：2012-01-09 00:00:00
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journal_title：Biomacromolecules
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更新日期：2017-08-14 00:00:00
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更新日期：2010-11-08 00:00:00
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journal_title：Biomacromolecules
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更新日期：2015-11-09 00:00:00
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