Rheology of gastric mucin exhibits a pH-dependent sol-gel transition.

abstract：:The objective of this study was to explore the use of reverse thermo-responsive (RTG) polymers for generating implants at their site of performance, following minimally invasive surgical procedures. Aiming at combining syringability and enhanced mechanical properties, a new family of injectable RTG-displaying polymers...

journal_title：Biomacromolecules

authors： Cohn D,Sosnik A,Garty S

更新日期：2005-05-01 00:00:00

abstract：:We report a facile method of generating ultradense poly(l-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG) surface by using high temperature alone, which in turn provides dramatic improvement in resisting nonspecific bioadsorption. X-ray photoelectron spectroscopy (XPS) revealed that the surface graft density increased...

journal_title：Biomacromolecules

authors： Ogaki R,Zoffmann Andersen O,Jensen GV,Kolind K,Kraft DC,Pedersen JS,Foss M

更新日期：2012-11-12 00:00:00

abstract：:Despite numerous strategies involving dynamic covalent bonds to produce self-healing hydrogels with similar frequency-dependent stiffness to native tissues, it remains challenging to use biologically relevant thiol/disulfide exchange to confer such properties to polymeric networks. Herein, we report a new method based...

journal_title：Biomacromolecules

authors： Casuso P,Odriozola I,Pérez-San Vicente A,Loinaz I,Cabañero G,Grande HJ,Dupin D

更新日期：2015-11-09 00:00:00

abstract：:Previously, we have shown that the amphiphilic decyl esters of both D- and L-tyrosine (DELT) self-assemble in aqueous solution above their critical micelle concentration values to form long rodlike structures that can be enzymatically polymerized. In the current study, we have examined the self-assembled structures of...

journal_title：Biomacromolecules

authors： Marx KA,Lee JS,Sung C

更新日期：2004-09-01 00:00:00

abstract：:Photosensitive supramolecular micelles, a combination of intermolecular hydrogen bonds between complementary adenine (A) and uracil (U) groups and a blend of two types of supramolecular polymers, can stably self-assemble into structurally stable, spherical micelles in aqueous solution before and after photoirradiation...

journal_title：Biomacromolecules

authors： Abebe Alemayehu Y,Tewabe Gebeyehu B,Cheng CC

更新日期：2019-12-09 00:00:00

abstract：:Biomimetic mineralization of collagen is an advantageous method to obtain resorbable collagen/hydroxy-apatite composites for application in bone regeneration. In this report, established procedures for mineralization of bovine collagen were adapted to a new promising source of collagen from salmon skin challenged by t...

journal_title：Biomacromolecules

authors： Hoyer B,Bernhardt A,Heinemann S,Stachel I,Meyer M,Gelinsky M

更新日期：2012-04-09 00:00:00

abstract：:A series of copolymers of trimethylene carbonate (TMC) and L-lactide (LLA) were synthesized and evaluated as scaffolds for the production of artificial blood vessels. The polymers were end-functionalized with acrylate, cast into films, and cross-linked using UV light. The mechanical, degradation, and biocompatibility ...

journal_title：Biomacromolecules

authors： Dargaville BL,Vaquette C,Peng H,Rasoul F,Chau YQ,Cooper-White JJ,Campbell JH,Whittaker AK

更新日期：2011-11-14 00:00:00

abstract：:Preparations of the highly ordered monoantennary, homofunctional diantennary, and heterofunctional diantennary neoglycopolymers of α-d-mannose and β-d-glucose residues were achieved via ring-opening metathesis polymerization. Isothermal titration calorimetry measurements of these synthetic neoglycopolymers with Concan...

journal_title：Biomacromolecules

authors： Loka RS,McConnell MS,Nguyen HM

更新日期：2015-12-14 00:00:00

abstract：:Chitin is a nitrogen-rich polysaccharide that is abundant in crustaceans, mollusks, insects, and fungi and is the second most abundant organic material found in nature next to cellulose. Chitosan, the N-deacetylated derivative of chitin, is environmentally friendly, nontoxic, biodegradable, and antibacterial. Fibrous ...

journal_title：Biomacromolecules

authors： Schiffman JD,Schauer CL

更新日期：2007-09-01 00:00:00

abstract：:Oral delivery remains a challenge for poorly permeable hydrophilic macromolecules. Poly(amido amine) (PAMAM) dendrimers have shown potential for their possible oral delivery. Transepithelial transport of carboxyl-terminated G3.5 and amine-terminated G4 PAMAM dendrimers was assessed using isolated rat jejunal mucosae m...

journal_title：Biomacromolecules

authors： Hubbard D,Ghandehari H,Brayden DJ

更新日期：2014-08-11 00:00:00

abstract：:Electrospinning is a simple and versatile technique of producing polymeric fibers ranging from submicron to micron in diameter. Incorporation of bioactive agents into the fibers could make a biofunctional tissue engineering scaffold. In this study, we investigated the feasibility of encapsulating human beta-nerve grow...

journal_title：Biomacromolecules

authors： Chew SY,Wen J,Yim EK,Leong KW

更新日期：2005-07-01 00:00:00

abstract：:Super-resolution fluorescence microscopy, specifically stochastic reconstruction microscopy (STORM), and atomic force microscopy (AFM) were used to image the self-assembly processes of the peptide surfactant I3K. The peptide surfactants self-assembled into giant helical fibrils with diameters between 5 and 10 nm with ...

journal_title：Biomacromolecules

authors： Cox H,Georgiades P,Xu H,Waigh TA,Lu JR

更新日期：2017-11-13 00:00:00

abstract：:Hydrogels are attractive materials for the controlled release of therapeutics because of their capacity to embed biologically active agents in their water-swollen network. Recent advances in organic and polymer chemistry, bioengineering and nanotechnology have resulted in several new developments in the field of hydro...

journal_title：Biomacromolecules

authors： Buwalda SJ,Vermonden T,Hennink WE

更新日期：2017-02-13 00:00:00

abstract：:In situ cross-linkable hybrid hydrogels composed of gelatin and 4-arm-polypropylene oxide-polyethylene oxide (Tetronic) was developed as an injectable scaffold for tissue regeneration. The gelatin was modified by hydroxyphenyl propionic acid (HPA) and the Tetronic was conjugated with tyramines (Tet-TA). The hydrogels ...

journal_title：Biomacromolecules

authors： Park KM,Lee Y,Son JY,Oh DH,Lee JS,Park KD

更新日期：2012-03-12 00:00:00

abstract：:The synthesis of poly(methyl methacrylate-co-methacryloxysuccinimide-graft-poly(ethylene glycol)) (PMMA-co-PMASI-g-PEG) via living free radical polymerization provides a convenient route to well-defined amphiphilic graft copolymers having a controllable number of reactive functional groups, variable length PEG grafts,...

journal_title：Biomacromolecules

authors： Pressly ED,Rossin R,Hagooly A,Fukukawa K,Messmore BW,Welch MJ,Wooley KL,Lamm MS,Hule RA,Pochan DJ,Hawker CJ

更新日期：2007-10-01 00:00:00

abstract：:Inspired by tea stains, plant polyphenolic tannic acid (TA) was beneficially employed as the primer anchor for functional polymer brushes. The brominated TA (TABr) initiator primer was synthesized by partial modification of TA with alkyl bromide functionalities. TABr with trihydroxyphenyl moieties can readily anchor o...

journal_title：Biomacromolecules

authors： Pranantyo D,Xu LQ,Neoh KG,Kang ET,Ng YX,Teo SL

更新日期：2015-03-09 00:00:00

abstract：:Aggregation phenomena in aqueous solutions of purified human tracheobronchial mucin have been studied by rheological methods, steady-state fluorescence, quasielastic light scattering, and spin probe techniques. At temperatures below 30 degrees C and concentrations above 15 mg/mL and in the absence of chaotropic agents...

journal_title：Biomacromolecules

authors： Bromberg LE,Barr DP

更新日期：2000-10-01 00:00:00

abstract：:The photoluminescence features of Eu(3+)-, Tb(3+)-, Tb(3+)/Eu(3+)-alginate aerogel (hydrogel and alcogel) and Eu(3+)-alginate xerogel hybrids were investigated. The Eu(3+)-alginate aerogel and alcogel exhibit the highest (5)D0 quantum efficiencies (9.9 and 8.2%, respectively), while the hydrogel and xerogel have lower...

journal_title：Biomacromolecules

authors： Liu F,Carlos LD,Ferreira RA,Rocha J,Gaudino MC,Robitzer M,Quignard F

更新日期：2008-07-01 00:00:00

abstract：:Forisomes are protein polymers found in leguminous plants that have the remarkable ability to undergo reversible "muscle-like" contractions in the presence of divalent cations and in extreme pH environments. To gain insight into the molecular basis of forisome structure and assembly, we used confocal laser scanning mi...

journal_title：Biomacromolecules

authors： Groscurth S,Müller B,Schwan S,Menzel M,Diekstall F,Senft M,Kendall A,Kommor BA,Neumann U,Kalischuk M,Kawchuk LM,Krzyzanek V,Heilmann A,Stubbs G,Twyman RM,Prüfer D,Noll GA

更新日期：2012-10-08 00:00:00

abstract：:A combination of chemo-photodynamic therapy has been manifested as a promising strategy for efficient cancer treatment due to the enhanced therapeutic efficacy. Here, we designed doxorubicin (DOX)-loaded photoresponsive micelles (DPRMs) based on a combination of chlorin e6 (Ce6) and lipoic acid (LA) conjugated methoxy...

journal_title：Biomacromolecules

authors： Kim DH,Hwang HS,Na K

更新日期：2018-08-13 00:00:00

abstract：:The morphology of silk produced by recluse spiders (Loxosceles arizonica) was investigated by scanning electron microscopy, atomic force microscopy, and transmission electron microscopy. This silk consisted entirely of very long, thin ribbons of width 2-4 microm and thicknesses of no more than 40 nm. The correspondenc...

journal_title：Biomacromolecules

authors： Coddington JA,Chanzy HD,Jackson CL,Raty G,Gardner KH

更新日期：2002-01-01 00:00:00

abstract：:Polypeptide-based formulations that undergo liquid to hydrogel transitions upon change in temperature have become desirable targets since they can be mixed with cells or injected into tissues as liquids, and subsequently transform into rigid scaffolds or depots. Such materials have been challenging to prepare using sy...

journal_title：Biomacromolecules

authors： Zhang S,Alvarez DJ,Sofroniew MV,Deming TJ

更新日期：2015-04-13 00:00:00

abstract：:The manufacture of biodegradable materials from agricultural sources is a real challenge, because of environmental concerns and the need to make full use of resources. Cottonseed is an important protein source that could be used in nonfood applications, as a substitute for synthetic polymers. For the first time, the v...

journal_title：Biomacromolecules

authors： Grevellec J,Marquié C,Ferry L,Crespy A,Vialettes V

更新日期：2001-01-01 00:00:00

abstract：:A shortage of available organ donors has created a need for engineered tissues. In this context, polymer-based hydrogels that break down inside the body are often used as constructs for growth factors and cells. Herein, we report imine cross-linked gels where degradation is controllable by the introduction of mixed im...

journal_title：Biomacromolecules

authors： Boehnke N,Cam C,Bat E,Segura T,Maynard HD

更新日期：2015-07-13 00:00:00

abstract：:Poly( n-butyl methacrylate) (PBMA) or poly( n-butyl acrylate) (PBA)-grafted brush coatings attached to glass were successfully prepared using atom-transfer radical polymerization "from the surface". The thicknesses and composition of the PBMA and PBA coatings were examined using ellipsometry and time-of-flight seconda...

journal_title：Biomacromolecules

authors： Awsiuk K,Stetsyshyn Y,Raczkowska J,Lishchynskyi O,Dąbczyński P,Kostruba A,Ohar H,Shymborska Y,Nastyshyn S,Budkowski A

更新日期：2019-06-10 00:00:00

abstract：:Crystal conversion of beta-chitin to alpha-chitin by aq. NaOH treatment was studied for a highly crystalline beta-chitin sample from diatom spine. The minimum NaOH concentration to cause swelling was between 25% and 30% w/w. The alkali-swollen material was poorly crystalline and was regenerated as alpha-chitin on wash...

journal_title：Biomacromolecules

authors： Noishiki Y,Takami H,Nishiyama Y,Wada M,Okada S,Kuga S

更新日期：2003-07-01 00:00:00

abstract：:The interaction of neuropeptides, vasoactive intestinal peptide (VIP), or growth hormone-releasing hormone (GHRH), with a cationic carbosilane dendrimer forms dendriplexes with antitumoral behavior in advanced prostate cancer cells PC3. At the concentrations used for dendriplexes formation, the free peptides were prot...

journal_title：Biomacromolecules

authors： Sánchez-Milla M,Muñoz-Moreno L,Sánchez-Nieves J,Malý M,Gómez R,Carmena MJ,de la Mata FJ

更新日期：2019-03-11 00:00:00

abstract：:New therapeutic strategies for the treatment of neoplastic pathologies and, in particular, metastasis processes are based on the inhibitory effect of angiogenic processes. The present article deals with the design, preparation, and application of new "polymer drugs" with a clear inhibitory effect of the activation of ...

journal_title：Biomacromolecules

authors： García-Fernández L,Aguilar MR,Fernández MM,Lozano RM,Giménez G,Valverde S,San Román J

更新日期：2010-07-12 00:00:00

abstract：:Hydrogels are able to mimic the basic three-dimensional (3D) biological, chemical, and mechanical properties of native tissues. Since hyaluronic acid (HA) is a chief component of human extracellular matrix (ECM), it represents an extremely attractive starting material for the fabrication of scaffolds for tissue engine...

journal_title：Biomacromolecules

authors： Kufelt O,El-Tamer A,Sehring C,Schlie-Wolter S,Chichkov BN

更新日期：2014-02-10 00:00:00

abstract：:Cationic spherical polyelectrolyte brushes (SPBs) were synthesized by photoemulsion polymerization, consisting of a polystyrene core with a diameter around 80 nm and a poly(2-aminoethylmethacrylate hydrochloride) (PAEMH) shell with a thickness from 10 to 50 nm densely grafted on the core surface. The binding of variou...

journal_title：Biomacromolecules

authors： Wang S,Chen K,Li L,Guo X

更新日期：2013-03-11 00:00:00