3D-Printing of Structure-Controlled Antigen Nanoparticles for Vaccine Delivery.

abstract：:A dual-sensitive polymeric drug conjugate (HA-SS-MP) was synthesized by conjugating hydrophobic 6-mercaptopurine (MP) to thiolated hyaluronic acid (HA) as the carrier and ligand to deliver doxorubicin (Dox) to parental colon cancer and colon cancer stem cells. Because of the amphiphilic nature of HA-SS-MP, it was self...

journal_title：Biomacromolecules

authors： Debele TA,Yu LY,Yang CS,Shen YA,Lo CL

更新日期：2018-09-10 00:00:00

abstract：:Inulin, the polydisperse polyfructose, extracted from chicory, has been modified via transesterification, using fatty acid methyl esters (FAME). The grafting of an alkyl chain onto the inulin backbone under different conditions for the development of potential tensio-active derivatives is described. The modification o...

journal_title：Biomacromolecules

authors： Rogge TM,Stevens CV

更新日期：2004-09-01 00:00:00

abstract：:The viscous mucus coating that adheres to the epithelial surfaces of mammalian organs provides protection for the underlying tissues and is an efficient barrier to drug delivery. Pulsed-gradient spin-echo NMR and small-angle neutron scattering have been used to study the aqueous solution interaction of various model p...

journal_title：Biomacromolecules

authors： Griffiths PC,Occhipinti P,Morris C,Heenan RK,King SM,Gumbleton M

更新日期：2010-01-11 00:00:00

abstract：:Safe delivery systems that can not only encapsulate hydrophobic drug molecules, but also release them in response to specific triggers are important in several therapeutic and biomedical applications. In this paper, we have designed a nanogel based on molecules that are generally recognized as safe (GRAS). We have sho...

journal_title：Biomacromolecules

authors： Prasad P,Molla MR,Cui W,Canakci M,Osborne B,Mager J,Thayumanavan S

更新日期：2015-11-09 00:00:00

abstract：:Electrically conducting polymeric membranes were prepared by incorporating multiwalled carbon nanotubes (MWCNTs) into bacterial cellulose pellicles produced by Gluconacetobacter xylinum. The MWCNTs were dispersed in a surfactant (cationic cetyl trimethylammonium bromide) solution, and cellulose pellicles were dipped i...

journal_title：Biomacromolecules

authors： Yoon SH,Jin HJ,Kook MC,Pyun YR

更新日期：2006-04-01 00:00:00

abstract：:The aim of this investigation was to understand and engineer the interactions between endothelial cells and the electrospun (ES) polyvinylidene fluoride-co-hexafluoropropylene (PVDF-HFP) nanofiber surfaces and evaluate their potential for endothelialization. Elastomeric PVDF-HFP samples were electrospun to evaluate th...

journal_title：Biomacromolecules

authors： Ahmed F,Dutta NK,Zannettino A,Vandyke K,Choudhury NR

更新日期：2014-04-14 00:00:00

abstract：:Vaginal films featuring the pH-dependent release of tenofovir (TFV) were developed for the prevention of sexual transmission of human immunodeficiency syndrome (HIV). Films based on hydroxypropyl methylcellulose and zein were prepared incorporating different plasticizers [oleic acid, lactic acid, glycerol, and polyeth...

journal_title：Biomacromolecules

authors： Notario-Pérez F,Cazorla-Luna R,Martín-Illana A,Galante J,Ruiz-Caro R,Sarmento B,das Neves J,Veiga MD

更新日期：2021-01-06 00:00:00

abstract：:Enzymatic hydrolysis of selected copolymers of cellulose diacetate-graft-poly(L-lactide)s (CDA-g-PLLAs) were conducted with proteinase K for film specimens, which were solely quenched from the molten state or, further, annealed at temperatures below or above their glass transition temperatures. The hydrolysis rates de...

journal_title：Biomacromolecules

authors： Teramoto Y,Nishio Y

更新日期：2004-03-01 00:00:00

abstract：:The maintenance of hepatocyte phenotype and functions remains as a great challenge in the generation of functional liver tissue and in vitro model for drug metabolism studies. The use of hepatocyte coculture systems plays essential roles in the establishment of cell-cell and cell-extracellular matrix communications si...

journal_title：Biomacromolecules

authors： Liu Y,Li H,Yan S,Wei J,Li X

更新日期：2014-03-10 00:00:00

abstract：:Oriented immobilization of proteins is an important step in creating protein-based functional materials. In this study, a method was developed to orient proteins on hydroxyapatite (HA) surfaces, a widely used bone implant material, to improve protein bioactivity by employing enhanced green fluorescent protein (EGFP) a...

journal_title：Biomacromolecules

authors： Yewle JN,Wei Y,Puleo DA,Daunert S,Bachas LG

更新日期：2012-06-11 00:00:00

abstract：:The intermolecular interactions of lignin with a hydrophilic polymer, poly(vinyl alcohol) (PVA), were studied using thermal analyses and FT-IR spectroscopy of a series of PVA/hardwood kraft lignin blend fibers prepared by thermal extrusion. Although two phases are observed in this blend system, some of the lignin was ...

journal_title：Biomacromolecules

authors： Kubo S,Kadla JF

更新日期：2003-05-01 00:00:00

abstract：:As a result of improved relevance to in vivo physiology, in vitro studies are increasingly performed in diverse, three-dimensional (3D) biomaterials. However, material-cell type pairing effects on cytokine availability remain unclear. We cultured five cell types in agarose, alginate, collagen, Matrigel, or RGD-functio...

journal_title：Biomacromolecules

authors： Regier MC,Montanez-Sauri SI,Schwartz MP,Murphy WL,Beebe DJ,Sung KE

更新日期：2017-03-13 00:00:00

abstract：:We report a biodegradable fluorescent theranostic nanoprobe design strategy for simultaneous visualization and quantitative determination of antibacterial activity for the treatment of bacterial infections. Cationic-charged polycaprolactone (PCL) was tailor-made through ring-opening polymerization methodology, and it ...

journal_title：Biomacromolecules

authors： Ghosh R,Malhotra M,Madhuri Sathe RR,Jayakannan M

更新日期：2020-07-13 00:00:00

abstract：:In a previous study, we have reported chemical synthesis of novel aliphatic poly(butylene succinate-co-cyclic carbonate) P(BS-co-CC)s bearing various functionalizable carbonate building blocks, and this work will continue to present our new studies on their enzymatic degradation and in vitro cell biocompatibility assa...

journal_title：Biomacromolecules

authors： Yang J,Tian W,Li Q,Li Y,Cao A

更新日期：2004-11-01 00:00:00

abstract：:We report the synthesis of PEG-coated, core-cross-linked polymeric micelles (CCPMs) derived from an amine-terminated amphiphilic block copolymer, poly(PEG-methacrylate)-b-poly(triethoxysilyl propylmethacrylate). The block copolymer self-assembled to form micellar nanoparticles, and a Cy-7-like near-infrared fluorescen...

journal_title：Biomacromolecules

authors： Yang Z,Zheng S,Harrison WJ,Harder J,Wen X,Gelovani JG,Qiao A,Li C

更新日期：2007-11-01 00:00:00

abstract：:Poly( n-butyl methacrylate) (PBMA) or poly( n-butyl acrylate) (PBA)-grafted brush coatings attached to glass were successfully prepared using atom-transfer radical polymerization "from the surface". The thicknesses and composition of the PBMA and PBA coatings were examined using ellipsometry and time-of-flight seconda...

journal_title：Biomacromolecules

authors： Awsiuk K,Stetsyshyn Y,Raczkowska J,Lishchynskyi O,Dąbczyński P,Kostruba A,Ohar H,Shymborska Y,Nastyshyn S,Budkowski A

更新日期：2019-06-10 00:00:00

abstract：:Hydrogels are promising materials for biomedical applications such as tissue engineering and controlled drug release. In the past two decades, the peptide hydrogel subclass has attracted an increasing level of interest from the scientific community because of its numerous advantages, such as biocompatibility, biodegra...

journal_title：Biomacromolecules

authors： Oyen E,Martin C,Caveliers V,Madder A,Van Mele B,Hoogenboom R,Hernot S,Ballet S

更新日期：2017-03-13 00:00:00

abstract：:Phase separation mechanisms and kinetics were studied using small-angle light scattering in a gelatin/maltodextrin system where phase separation could be studied in both liquid and gelled states. Nucleation and growth or spinodal decomposition occurred, depending on the quench depth. The transition between the two mec...

journal_title：Biomacromolecules

authors： Butler MF

更新日期：2002-07-01 00:00:00

abstract：:Poly(butylene adipate-co-terephthalate) (PBAT) was first chemically modified via free radical grafting with maleic anhydride (MA) and the MA-g-PBAT graft copolymer was then used as a matrix material to obtain cellulose nanocrystal (CNC)-reinforced MA-g-PBAT bionanocomposites via reactive extrusion process to accelerat...

journal_title：Biomacromolecules

authors： Kashani Rahimi S,Aeinehvand R,Kim K,Otaigbe JU

更新日期：2017-07-10 00:00:00

abstract：:A well-defined N-(2-hydroxypropyl)methacrylamide-s-N-(3-aminopropyl)methacrylamide (HPMA-s-APMA) copolymer, synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization, was utilized for the rational design of multiconjugates containing both a gene therapeutic, small interfering RNA (siRNA), ...

journal_title：Biomacromolecules

authors： York AW,Huang F,McCormick CL

更新日期：2010-02-08 00:00:00

abstract：:The structure of an extracellular polysaccharide (EPS) from Streptococcus thermophilus THS has been determined. A combination of component analysis, methylation analysis and NMR spectroscopy shows that the polysaccharide is composed of pentasaccharide repeating units. Sequential information was obtained by two-dimensi...

journal_title：Biomacromolecules

authors： Nordmark EL,Yang Z,Huttunen E,Widmalm G

更新日期：2005-01-01 00:00:00

abstract：:As with many other biosourced colloids, chitin nanocrystals (ChNCs) can form liquid crystalline phases with chiral nematic ordering. In this work, we demonstrate that it is possible to finely tune the liquid crystalline behavior of aqueous ChNC suspensions finely. Such control was made possible by carefully studying h...

journal_title：Biomacromolecules

authors： Narkevicius A,Steiner LM,Parker RM,Ogawa Y,Frka-Petesic B,Vignolini S

更新日期：2019-07-08 00:00:00

abstract：:Neutron reflectometry was used to investigate the time-dependent beta-casein adsorption at the silica-aqueous solution interface. The transient and steady-state structural characteristics of the adsorbed layer were determined from reflectivity curves, fitted to three-layer and two-layer models. The results show that t...

journal_title：Biomacromolecules

authors： Tiberg F,Nylander T,Su TJ,Lu JR,Thomas RK

更新日期：2001-10-01 00:00:00

abstract：:Ternary compatible blends of chitosan, poly(vinyl alcohol), and poly(lactic acid) were prepared by an oil-in-water (O/W) emulsion process. Solutions of chitosan in aqueous acetic acid, poly(vinyl alcohol) (PVA) in water, and poly(lactic acid) (PLA) in chloroform were blended with a high-shear mixer. PVA was used as an...

journal_title：Biomacromolecules

authors： Grande R,Carvalho AJ

更新日期：2011-04-11 00:00:00

abstract：:Combining molecular weight distribution (MWD) data for linear chains of debranched starch from capillary electrophoresis and from size exclusion chromatography (SEC) with detection by differential refractive index and by multi-angle laser light scattering has enabled Mark-Houwink parameters to be determined for linear...

journal_title：Biomacromolecules

authors： Castro JV,Ward RM,Gilbert RG,Fitzgerald MA

更新日期：2005-07-01 00:00:00

abstract：:This work reports on the effect of CO2 at subcritical conditions and the gaseous state on the telechelic poly(epsilon-caprolactone) polymers. The tested polymers are semi-crystalline in nature and thus the effect of functional groups and their overall contribution to foaming and formation of microstructures with open-...

journal_title：Biomacromolecules

authors： Nawaby AV,Farah AA,Liao X,Pietro WJ,Day M

更新日期：2005-09-01 00:00:00

abstract：:Despite the good clinical efficacy of interferon-alpha (IFNα) to treat some types of cancer and viral infections, this biological drug is underused given its severe adverse effects and high dosing parenteral regimens. Aiming to achieve a breakthrough in therapy with IFNα, this work reports for the first time on the de...

journal_title：Biomacromolecules

authors： Cánepa C,Imperiale JC,Berini CA,Lewicki M,Sosnik A,Biglione MM

更新日期：2017-10-09 00:00:00

abstract：:Elastin-like peptides (ELPs) have been used widely to confer thermoresponsive characteristics onto various materials, but to this point mostly linear ELPs have been studied. A class of linear and dendritic (branched) ELPs based on the GLPGL pentamer repeat unit was synthesized using an on-resin divergent strategy. The...

journal_title：Biomacromolecules

authors： Navon Y,Zhou M,Matson JB,Bitton R

更新日期：2016-01-11 00:00:00

abstract：:The antiproliferative activity of alkylated heparin, in which the terminal end of heparin is derivatized with an alkyl group (butyl, octyl, lauryl, stearyl), was examined using vascular smooth muscle cells. The proliferation of cells, which were growth-arrested prior to addition of heparin, was inhibited in proportion...

journal_title：Biomacromolecules

authors： Gohda M,Magoshi T,Kato S,Noguchi T,Yasuda S,Nonogi H,Matsuda T

更新日期：2001-01-01 00:00:00

abstract：:A new, convenient pathway is developed to synthesize highly hydrolytically labile poly(ortho ester amide) (POEA) copolymers that overcomes some of the major weaknesses of the traditional methods of synthesizing poly(ortho esters) and their derivatives. A diamine monomer containing a built-in, stabilized ortho ester gr...

journal_title：Biomacromolecules

authors： Tang R,Palumbo RN,Ji W,Wang C

更新日期：2009-04-13 00:00:00