SEC-MALS-QELS study on the molecular conformation of cellulose in LiCl/amide solutions.

abstract：:In the fields of surgery and regenerative medicine, it is crucial to understand the interactions of proteins with the biomaterials used as implants. Protein adsorption directly influences cell-material interactions in vivo and, as a result, regulates, for example, cell adhesion on the surface of the implant. Therefore...

journal_title：Biomacromolecules

authors： Schönwälder SM,Bally F,Heinke L,Azucena C,Bulut ÖD,Heißler S,Kirschhöfer F,Gebauer TP,Neffe AT,Lendlein A,Brenner-Weiß G,Lahann J,Welle A,Overhage J,Wöll C

更新日期：2014-07-14 00:00:00

abstract：:Block copolypeptides, which combine the self-assembly of block copolymers and the highly ordered 3D structures of proteins, are potential candidates for novel supramolecular structures and biotech applications, such as biosensors, tissue engineering, and selective drug delivery. The synthesis of model block copolypept...

journal_title：Biomacromolecules

authors： Aliferis T,Iatrou H,Hadjichristidis N

更新日期：2004-09-01 00:00:00

abstract：:Poly(ethylene 2,5-furandicarboxylate) (PEF) is a biobased polyester characterized by high gas barrier properties as well as high tensile modulus and strength, but poor toughness. Toughening PEF without sacrificing its modulus, strength and gas barrier performance is a great challenge for PEF modification. In this stud...

journal_title：Biomacromolecules

authors： Xie H,Wu L,Li BG,Dubois P

更新日期：2019-01-14 00:00:00

abstract：:Polycaprolactone (PCL) was reported a long time ago; however, its biomedical applications has not been extensively investigated in comparison with poly(lactide- co-glycolide) (PLGA) due to its too slow degradation profile. Here, we are reporting an oxalate-connected oligocaprolactone multiblock copolymer (PCL-OX) as a...

journal_title：Biomacromolecules

authors： Chang SH,Lee HJ,Park S,Kim Y,Jeong B

更新日期：2018-06-11 00:00:00

abstract：:Selectively spooling single plasmid DNA (pDNA), as a giant polyelectrolyte, into a nanosized toroidal structure or folding it into a rod-like structure has been accomplished by polyion complexation with block catiomers to form polymeric micelles in varying NaCl concentrations. The interactive potency between the pDNA ...

journal_title：Biomacromolecules

authors： Li Y,Osada K,Chen Q,Tockary TA,Dirisala A,Takeda KM,Uchida S,Nagata K,Itaka K,Kataoka K

更新日期：2015-09-14 00:00:00

abstract：:Dynamic shear oscillation measurements at small strain were used to characterize the viscoelastic properties and related differences in the molecular structure of hydrogels based on gelatin methacrylamide. Gelatin was derivatized with methacrylamide side groups and was subsequently cross-linked by radical polymerizati...

journal_title：Biomacromolecules

authors： Van Den Bulcke AI,Bogdanov B,De Rooze N,Schacht EH,Cornelissen M,Berghmans H

更新日期：2000-04-01 00:00:00

abstract：:Polyamines are essential molecules supporting the structure, conformation, and function of nucleic acids and proteins. We studied stereoisomers of alpha,alpha'-dimethylated spermine [(R,R)-Me(2)Spm, (S,S)-Me(2)Spm, (R,S)-Me(2)Spm] for their ability to provoke DNA condensation and protect DNA from damage. (R,R)- and (R...

journal_title：Biomacromolecules

authors： Nayvelt I,Hyvönen MT,Alhonen L,Pandya I,Thomas T,Khomutov AR,Vepsäläinen J,Patel R,Keinänen TA,Thomas TJ

更新日期：2010-01-11 00:00:00

abstract：:The ability to direct neurite growth into a close proximity of stimulating elements of a neural prosthesis, such as a retinal or cochlear implant (CI), may enhance device performance and overcome current spatial signal resolution barriers. In this work, spiral ganglion neurons (SGNs), which are the target neurons to b...

journal_title：Biomacromolecules

authors： Tuft BW,Zhang L,Xu L,Hangartner A,Leigh B,Hansen MR,Guymon CA

更新日期：2014-10-13 00:00:00

abstract：:Cationic spherical polyelectrolyte brushes (SPBs) were synthesized by photoemulsion polymerization, consisting of a polystyrene core with a diameter around 80 nm and a poly(2-aminoethylmethacrylate hydrochloride) (PAEMH) shell with a thickness from 10 to 50 nm densely grafted on the core surface. The binding of variou...

journal_title：Biomacromolecules

authors： Wang S,Chen K,Li L,Guo X

更新日期：2013-03-11 00:00:00

abstract：:As a result of improved relevance to in vivo physiology, in vitro studies are increasingly performed in diverse, three-dimensional (3D) biomaterials. However, material-cell type pairing effects on cytokine availability remain unclear. We cultured five cell types in agarose, alginate, collagen, Matrigel, or RGD-functio...

journal_title：Biomacromolecules

authors： Regier MC,Montanez-Sauri SI,Schwartz MP,Murphy WL,Beebe DJ,Sung KE

更新日期：2017-03-13 00:00:00

abstract：:Cardiovascular diseases plague human health because of the lack of transplantable small-diameter blood vessel (SDBV) grafts. Although expanded polytetrafluoroethylene (ePTFE) has the potential to be used as a biocompatible material for SDBV grafts, long-term patency is still the biggest challenge. As discussed in this...

journal_title：Biomacromolecules

authors： Wang D,Xu Y,Lin YJ,Yilmaz G,Zhang J,Schmidt G,Li Q,Thomson JA,Turng LS

更新日期：2020-09-14 00:00:00

abstract：:Reversible addition-fragmentation chain transfer (RAFT) radical polymerization, mediated by 4-cyanopentanoic acid dithiobenzoate and 4,4'-azobis(4-cyanovaleric acid) (V-501) in water at 70 degrees C, of biocompatible 2-(methacryloyloxy)ethyl phosphorylcholine (MPC) yields a macro-chain transfer agent (CTA) that was em...

journal_title：Biomacromolecules

authors： Yu B,Lowe AB,Ishihara K

更新日期：2009-04-13 00:00:00

abstract：:Combining molecular weight distribution (MWD) data for linear chains of debranched starch from capillary electrophoresis and from size exclusion chromatography (SEC) with detection by differential refractive index and by multi-angle laser light scattering has enabled Mark-Houwink parameters to be determined for linear...

journal_title：Biomacromolecules

authors： Castro JV,Ward RM,Gilbert RG,Fitzgerald MA

更新日期：2005-07-01 00:00:00

abstract：:Collagen fibrils were obtained in vitro by aggregation from acid-soluble type I collagen at different initial concentrations and with the addition of decorin core or intact decorin. All specimens were observed by scanning electron microscopy and atomic force microscopy. In line with the findings of other authors, lack...

journal_title：Biomacromolecules

authors： Raspanti M,Viola M,Sonaggere M,Tira ME,Tenni R

更新日期：2007-07-01 00:00:00

abstract：:Heparins are widely used to prevent blood clotting during surgeries and for the treatment of thrombosis. However, bleeding associated with heparin therapy is a concern. Protamine, the only approved antidote for unfractionated heparin (UFH) could cause adverse cardiovascular events. Here, we describe a unique molecular...

journal_title：Biomacromolecules

authors： Kalathottukaren MT,Abbina S,Yu K,Shenoi RA,Creagh AL,Haynes C,Kizhakkedathu JN

更新日期：2017-10-09 00:00:00

abstract：:Degradable polymers with specifically designed functionality have wide applications in biomedical fields. We reported herein the synthesis and characterization of a water-soluble and fast-degradable polycarbonate, functionalized with tertiary amine groups in the backbone. A novel cyclic carbonate monomer, namely, 6,14...

journal_title：Biomacromolecules

authors： Wang HF,Su W,Zhang C,Luo XH,Feng J

更新日期：2010-10-11 00:00:00

abstract：:Self-assembling amphiphilic designer peptides have been successfully applied as nanomaterials in biomedical applications. Understanding molecular interactions at the peptide-membrane interface is crucial, since interactions at this site often determine (in)compatibility. The present study aims to elucidate how model m...

journal_title：Biomacromolecules

authors： Kornmueller K,Lehofer B,Meindl C,Fröhlich E,Leitinger G,Amenitsch H,Prassl R

更新日期：2016-11-14 00:00:00

abstract：:Most biopolymers exist in a plasticized state, whether it is naturally with water or unnaturally with glycerol or other suitable polyol, to make a flexible material. We have found that the extent to which a biopolymer can be plasticized is dependent on its molecular and higher order structures outside of simply molecu...

journal_title：Biomacromolecules

authors： Athamneh AI,Griffin M,Whaley M,Barone JR

更新日期：2008-11-01 00:00:00

abstract：:Oral delivery remains a challenge for poorly permeable hydrophilic macromolecules. Poly(amido amine) (PAMAM) dendrimers have shown potential for their possible oral delivery. Transepithelial transport of carboxyl-terminated G3.5 and amine-terminated G4 PAMAM dendrimers was assessed using isolated rat jejunal mucosae m...

journal_title：Biomacromolecules

authors： Hubbard D,Ghandehari H,Brayden DJ

更新日期：2014-08-11 00:00:00

abstract：:Strategies to prevent the uptake of modified low density lipoproteins (LDLs) by immune cells, a major trigger of inflammation and atherogenesis, are challenged by complex interfacial factors governing LDL receptor-mediated uptake. We examine a new approach based on a family of "nanoblockers", which are designed to exa...

journal_title：Biomacromolecules

authors： Chnari E,Nikitczuk JS,Wang J,Uhrich KE,Moghe PV

更新日期：2006-06-01 00:00:00

abstract：:Enzymatic hydrolysis of selected copolymers of cellulose diacetate-graft-poly(L-lactide)s (CDA-g-PLLAs) were conducted with proteinase K for film specimens, which were solely quenched from the molten state or, further, annealed at temperatures below or above their glass transition temperatures. The hydrolysis rates de...

journal_title：Biomacromolecules

authors： Teramoto Y,Nishio Y

更新日期：2004-03-01 00:00:00

abstract：:Nanofibrous biocomposite scaffolds of type I collagen and nanohydroxyapatite (nanoHA) of varying compositions (wt %) were prepared by electrostatic cospinning. The scaffolds were characterized for structure and morphology by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), atomic fo...

journal_title：Biomacromolecules

authors： Thomas V,Dean DR,Jose MV,Mathew B,Chowdhury S,Vohra YK

更新日期：2007-02-01 00:00:00

abstract：:Despite great potential, the delivery of genetic materials into cells or tissues of interest remains challenging owing to their susceptibility to nuclease degradation, lack of permeability to the cell membrane, and short in vivo half-life, which severely restrict their widespread use in therapeutics. To surmount these...

journal_title：Biomacromolecules

authors： Le TMD,Duong HTT,Thambi T,Giang Phan VH,Jeong JH,Lee DS

更新日期：2018-08-13 00:00:00

abstract：:We describe a facile method to amine functionalize and subsequently fluorescently label polymethacrylamides synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. RAFT-generated poly(N-(2-hydroxypropyl) methacrylamide-b-N-[3-(dimethylamino)propyl] methacrylamide) (poly(HPMA-b-DMAPMA)),...

journal_title：Biomacromolecules

authors： York AW,Scales CW,Huang F,McCormick CL

更新日期：2007-08-01 00:00:00

abstract：:A cellulose macromonomer, N-(15-methacryloyloxypentadecanoyl)-tri-O-acetyl-beta-cellulosylamine (CTA-C15-MA (2); M(2)) with number averaged degree of polymerization (DP(n)) = 13), was copolymerized with methyl methacrylate (MMA; M(1)) to give cellulosic copolymer with CTA side chains, PMMA-g-(CTA-C15) (3-A). An absolu...

journal_title：Biomacromolecules

authors： Enomoto-Rogers Y,Kamitakahara H,Takano T,Nakatsubo F

更新日期：2009-08-10 00:00:00

abstract：:Cellular uptake and intracellular targeting to specific organelles are key events in the cellular processing of nanomaterials. Herein, we perform a detailed structure-property relationship study on carboxylic acid-side-chain-bearing polyacrylates to provide design criteria for the manipulation of their cellular intera...

journal_title：Biomacromolecules

authors： Mahmoud AM,Morrow JP,Pizzi D,Azizah AM,Davis TP,Tabor RF,Kempe K

更新日期：2020-08-10 00:00:00

abstract：:A strategy to manipulate the disulfide bond breaking triggered unfolding, and subsequently assembly of human serum albumin (HSA) in a lipophilic drug-dependent manner is present. In this study, the hydrophobic region, a molecular switch of the HSA, was regulated to form HSA-paclitaxel (HSA-PTX) nanoparticles by a faci...

journal_title：Biomacromolecules

authors： Gong G,Xu Y,Zhou Y,Meng Z,Ren G,Zhao Y,Zhang X,Wu J,Hu Y

更新日期：2012-01-09 00:00:00

abstract：:The conformational behavior of a long single-chain double-stranded DNA in solutions of free silver ions and silver nanoparticles generated via the reduction of AgNO3 by NaBH4 was monitored by fluorescence and electron microscopies and UV spectroscopy. The interaction of monovalent silver ions with DNA induces shrinkin...

journal_title：Biomacromolecules

authors： Zinchenko AA,Baigl D,Chen N,Pyshkina O,Endo K,Sergeyev VG,Yoshikawa K

更新日期：2008-07-01 00:00:00

abstract：:The synergistic interaction between xanthan and glucomannan in solution and in the gel phase has been studied by circular dichroism spectroscopy and differential scanning calorimetry. The study in solution of the polysaccharidic mixture indicates a preferred stoichiometry of the interaction corresponding to a weight f...

journal_title：Biomacromolecules

authors： Paradossi G,Chiessi E,Barbiroli A,Fessas D

更新日期：2002-05-01 00:00:00

abstract：:The dynamics of bacterial colonies is complex in nature because it correlates the behavior of numerous individual cells in space and time and is characterized by emergent properties such as virulence or antibiotics resistance. Because there is no clear-cut evidence that periodic swarming of P. mirabilis colonies is ru...

journal_title：Biomacromolecules

authors： Lahaye E,Aubry T,Kervarec N,Douzenel P,Sire O

更新日期：2007-04-01 00:00:00