Abstract:
:The dynamics of bacterial colonies is complex in nature because it correlates the behavior of numerous individual cells in space and time and is characterized by emergent properties such as virulence or antibiotics resistance. Because there is no clear-cut evidence that periodic swarming of P. mirabilis colonies is ruled by chemical triggers responsible for cell-to-cell signaling in most of the biofilms, we propose that the observed periodicity relies on the colony's global properties. Hence, the biochemical and functional properties of the extracellular matrix (ECM) of P. mirabilis colonies were investigated. A binary exopolysaccharide mixture (1 and 300 kDa), glycinebetaine, and a phenoglycolipid were identified. Rheology, calorimetry, and water sorption experiments performed on purified EPS bring evidence that these exoproducts exhibit marked viscoelasticity, which likely relies on large scale H bond networks. Such behavior is discussed in terms of water activity because the mechanical ECM properties were found to depend on hydration.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Lahaye E,Aubry T,Kervarec N,Douzenel P,Sire Odoi
10.1021/bm061181lsubject
Has Abstractpub_date
2007-04-01 00:00:00pages
1218-27issue
4eissn
1525-7797issn
1526-4602journal_volume
8pub_type
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