Nature of interactions between PEO-PPO-PEO triblock copolymers and lipid membranes: (I) effect of polymer hydrophobicity on its ability to protect liposomes from peroxidation.

abstract：:The maintenance of hepatocyte phenotype and functions remains as a great challenge in the generation of functional liver tissue and in vitro model for drug metabolism studies. The use of hepatocyte coculture systems plays essential roles in the establishment of cell-cell and cell-extracellular matrix communications si...

journal_title：Biomacromolecules

authors： Liu Y,Li H,Yan S,Wei J,Li X

更新日期：2014-03-10 00:00:00

abstract：:Control of the photoluminescence properties of cellulose is conducted by introduction of conducting polymers including fluorene (F) and 3-hexylthiophene (3HT) on cellulose surface through FeCl3 oxidative polymerization. The UV-vis absorption peak of cellulose grafted with the 3-hexylthiophene and fluorene copolymer wa...

journal_title：Biomacromolecules

authors： Phung Hai TA,Sugimoto R

更新日期：2017-12-11 00:00:00

abstract：:Nanoparticles (NPs) composed of chitosan (CS) and poly(gamma-glutamic acid) (gamma-PGA) were prepared by a simple ionic-gelation method for oral insulin delivery. Fourier transform infrared (FT-IR) spectra indicated that CS and gamma-PGA were ionized at pH 2.5-6.6, while X-ray diffractograms demonstrated that the crys...

journal_title：Biomacromolecules

authors： Lin YH,Mi FL,Chen CT,Chang WC,Peng SF,Liang HF,Sung HW

更新日期：2007-01-01 00:00:00

abstract：:Tissue engineering approaches for peripheral nerve regeneration employ biodegradable scaffolds coupled with growth factors for improved performance in regeneration of large nerve injuries. Electrospun nanofibers provide a versatile platform for fabrication of scaffolds with extracellular matrix like architecture and i...

journal_title：Biomacromolecules

authors： Valmikinathan CM,Defroda S,Yu X

更新日期：2009-05-11 00:00:00

abstract：:A comprehensive knowledge of the in vivo fate of polymers is essential for their potential application in humans. In this study, the body distribution, accumulation, and elimination processes of intraperitoneally (ip) administered poly(vinyl alcohol) (PVA) in mice were investigated in detail. Two derivatives of PVA (1...

journal_title：Biomacromolecules

authors： Schädlich A,Naolou T,Amado E,Schöps R,Kressler J,Mäder K

更新日期：2011-10-10 00:00:00

abstract：:RNA interference (RNAi) requires the intracellular delivery of RNA molecules to initiate the neutralization of targeted mRNA molecules, inhibiting the expression or translation of the targeted gene. Current polymers and lipids that are used to deliver RNA molecules are generally required to be positively charged, to a...

journal_title：Biomacromolecules

authors： Jiang Z,Cui W,Prasad P,Touve MA,Gianneschi NC,Mager J,Thayumanavan S

更新日期：2019-01-14 00:00:00

abstract：:Development of versatile nanoscale platforms for cancer diagnosis and therapy is of great importance for applications in translational medicine. In this work, we present the use of γ-polyglutamic acid (γ-PGA) nanogels (NGs) to load polypyrrole (PPy) for thermal/photoacoustic (PA) imaging and radiotherapy (RT)-sensitiz...

journal_title：Biomacromolecules

authors： Zhou Y,Hu Y,Sun W,Lu S,Cai C,Peng C,Yu J,Popovtzer R,Shen M,Shi X

更新日期：2018-06-11 00:00:00

abstract：:Poly(lactide)-block-poly(ethylene oxide)-block-poly(lactide) (PLA-PEO-PLA) triblock copolymers are known to form physical hydrogels in water as a result of the polymer's amphiphilicity. Their mechanical properties, biocompatibility, and biodegradability have made them attractive for use as soft tissue scaffolds. Howev...

journal_title：Biomacromolecules

authors： Sanabria-DeLong N,Crosby AJ,Tew GN

更新日期：2008-10-01 00:00:00

abstract：:This paper reports the rheological behavior of chitosan solutions that have been cross-linked with different amounts of genipin, at body temperature and physiological pH. The effect of the cross-linker loading on the rheological properties of hydrogels has been evaluated. The oscillatory time sweep method was used to ...

journal_title：Biomacromolecules

authors： Moura MJ,Figueiredo MM,Gil MH

更新日期：2007-12-01 00:00:00

abstract：:The stability of internally cross-linked casein micelles against disruption by urea (which disrupts hydrogen bonds and hydrophobic interactions) and trisodium citrate (which sequesters micellar calcium phosphate) was investigated. Addition of urea (0-6 mol L-1) and/or citrate (0-50 mmol L-1) progressively reduced the ...

journal_title：Biomacromolecules

authors： Huppertz T,Smiddy MA,de Kruif CG

更新日期：2007-04-01 00:00:00

abstract：:Biodegradable polyrotaxanes (PRXs) were synthesized from bis-amino-terminated poly(L-lactide) (PLLA) and alpha-cyclodextrin (alpha-CD), combined with capping by bulky end groups at the amino-termini of PLLA through enzymatically cleavable peptide linkages. The crystalline structure of the PRXs in the solid state was i...

journal_title：Biomacromolecules

authors： Ohya Y,Takamido S,Nagahama K,Ouchi T,Katoono R,Yui N

更新日期：2009-08-10 00:00:00

abstract：:Thermoresponsive anionic copolymer brushes, poly(N-isopropylacrylamide-co-acrylic acid-co-tert-butylacrylamide) [P(IPAAm-co-AAc-co-tBAAm)], were grafted onto a monolithic silica rod column through surface-initiated atom-transfer radical polymerization (ATRP) to prepare an effective thermoresponsive anionic chromatogra...

journal_title：Biomacromolecules

authors： Nagase K,Kobayashi J,Kikuchi A,Akiyama Y,Kanazawa H,Okano T

更新日期：2014-04-14 00:00:00

abstract：:In the present study, we monitored the conformation and chemical stability of a hydrophilic bottlebrush (BB) polymer in pure water and buffered saline solutions. We correlated these parameters to lubricating and wear protecting properties. Using the surface forces apparatus (SFA), we show that the BB polymer partially...

journal_title：Biomacromolecules

authors： Faivre J,Shrestha BR,Xie G,Delair T,David L,Matyjaszewski K,Banquy X

更新日期：2017-12-11 00:00:00

abstract：:A revised crystal structure for mercerized cellulose based on high-resolution synchrotron X-ray data collected from ramie fibers is reported (space group P2(1), a = 8.10(3) A, b = 9.03(3) A, c = 10.31(5) A, gamma = 117.10(5) degrees; 751 reflections in 304 composite spots; theta < 21.11 degrees; lambda = 0.7208 A; LAL...

journal_title：Biomacromolecules

authors： Langan P,Nishiyama Y,Chanzy H

更新日期：2001-07-01 00:00:00

abstract：:Novel polymer composites reinforced with an oriented cellulose nanocrystal (CNC) assembly were prepared from suspensions of CNC in aqueous 2-hydroxyethyl methacrylate (HEMA) via magnetic field application to the suspensions followed by polymerization treatment. The starting suspensions used at ∼6 wt % CNC separated in...

journal_title：Biomacromolecules

authors： Tatsumi M,Kimura F,Kimura T,Teramoto Y,Nishio Y

更新日期：2014-12-08 00:00:00

abstract：:The supramolecular organization of self-assembled stoichiometric complexes formed by dodecyltrimethylammonium cations and ionized poly(gamma-glutamic) acid has been investigated in chloroform solution. Atomistic molecular dynamics simulations have been performed considering three different starting conformations for t...

journal_title：Biomacromolecules

authors： Zanuy D,Alemán C

更新日期：2007-02-01 00:00:00

abstract：:In this paper we extend our previous experimental work on interaction between polyelectrolytes and liposomes. First, the adsorption of chitosan and alkylated chitosan (cationic polyelectrolytes) with different alkyl chain lengths on lipid membranes of liposomes is examined. The amount of both chitosans adsorbed remain...

journal_title：Biomacromolecules

authors： Quemeneur F,Rinaudo M,Pépin-Donat B

更新日期：2008-08-01 00:00:00

abstract：:The morphologies of several ionotropic alginate hydrogels and aerogels were investigated by SAXS according to the nature of the divalent metal cation (Mn(2+), Co(2+), Zn(2+), Cu(2+)) and the guluronic fraction of the alginate. All alginate hydrogel and aerogel samples show isotropic small-angle X-ray scattering. Gelat...

journal_title：Biomacromolecules

authors： Agulhon P,Robitzer M,David L,Quignard F

更新日期：2012-01-09 00:00:00

abstract：:Controlling self-assembly is critical to the advancement of nanotechnology. A rugged or crenated assembly energy surface can redirect assembly off path. By using a defined starting point and an energy surface made rough by a strong association energy, we can impose entirely new assembly paths and products. Normally, t...

journal_title：Biomacromolecules

authors： Burns K,Mukherjee S,Keef T,Johnson JM,Zlotnick A

更新日期：2010-02-08 00:00:00

abstract：:A three-dimensional structure consisting of poly(ε-caprolactone) (PCL) nanofibers covered by periodically spaced PCL crystal lamellae, a self-induced nanohybrid shish-kebab (SINSK) structure, was created using electrospinning followed by a self-induced crystallization. The resulting structure that resembles the nanoto...

journal_title：Biomacromolecules

authors： Wang X,Salick MR,Wang X,Cordie T,Han W,Peng Y,Li Q,Turng LS

更新日期：2013-10-14 00:00:00

abstract：:We present a new design of peptide-polymer conjugates where a polymer chain is covalently linked to the side chain of a helix bundle-forming peptide. The effect of conjugated polymer chains on the peptide structure was examined using a de novo designed three-helix bundle and a photoactive four-helix bundle. Upon attac...

journal_title：Biomacromolecules

authors： Shu JY,Tan C,DeGrado WF,Xu T

更新日期：2008-08-01 00:00:00

abstract：:Recently, we have developed a photopolymerizable poly(L-lysine) (PLL) that can be covalently incorporated into poly(ethylene glycol) diacrylate (PEGDA) hydrogels to improve their bioactivity by providing positive charges. To explore the potential of these PLL-grafted PEGDA hydrogels as a cell delivery vehicle and lumi...

journal_title：Biomacromolecules

authors： Cai L,Lu J,Sheen V,Wang S

更新日期：2012-05-14 00:00:00

abstract：:Receptor-mediated, cell-specific delivery of siRNA enables silencing of target genes in specific tissues, opening the door to powerful therapeutic options for a multitude of diseases. However, the development of delivery systems capable of targeted and effective siRNA delivery typically requires multiple steps and the...

journal_title：Biomacromolecules

authors： Benoit DS,Srinivasan S,Shubin AD,Stayton PS

更新日期：2011-07-11 00:00:00

abstract：:Enzymatic ring-opening copolymerization of 5-benzyloxy-trimethylene carbonate (BTMC) and 1,4-dioxan-2-one (DON) was investigated for the first time. Immobilized porcine pancreas lipase (IPPL) on silica particles was selected to perform the copolymerization. A series of novel biodegradable copolymers with different com...

journal_title：Biomacromolecules

authors： He F,Jia HL,Liu G,Wang YP,Feng J,Zhuo RX

更新日期：2006-08-01 00:00:00

abstract：:We have investigated the self-assembly of fluorenylmethoxycarbonyl-conjugated dialanine (Fmoc-AA) molecules using combined computational and experimental approaches. Fmoc-AA gels were characterized using transmission electron microscopy (TEM), circular dichroism (CD), Fourier transform infrared (FTIR), and wide-angle ...

journal_title：Biomacromolecules

authors： Mu X,Eckes KM,Nguyen MM,Suggs LJ,Ren P

更新日期：2012-11-12 00:00:00

abstract：:New type of N-glycosylated peptides having periodic sequence of -[X-Gln(beta-D-GlcNAc)-Aib]- [X = L-Glu(OMe), L-Lys(Ac), L-Ala; Aib = alpha-aminoisobutyric acid] were synthesized by polymerization of glycosylated tripeptides with an active ester methods using Cl(-+)H(3)N-L-Glu(OMe)-Gln[beta-D-GlcNAc(Ac)(3)]-Aib-ONp (N...

journal_title：Biomacromolecules

authors： Takasu A,Horikoshi S,Hirabayashi T

更新日期：2005-07-01 00:00:00

abstract：:Enzymatic hydrolysis of selected copolymers of cellulose diacetate-graft-poly(L-lactide)s (CDA-g-PLLAs) were conducted with proteinase K for film specimens, which were solely quenched from the molten state or, further, annealed at temperatures below or above their glass transition temperatures. The hydrolysis rates de...

journal_title：Biomacromolecules

authors： Teramoto Y,Nishio Y

更新日期：2004-03-01 00:00:00

abstract：:Poly(L-lactide)-based microspheres having cationic or anionic surfaces were prepared using polydepsipeptide-block-poly(L-lactide)s as surfactants. Polydepsipeptide-block-poly(L-lactide)s having amino or carboxylic acid groups on their side chains were synthesized through anionic ring-opening polymerizations of L-lacti...

journal_title：Biomacromolecules

authors： Ouchi T,Toyohara M,Arimura H,Ohya Y

更新日期：2002-09-01 00:00:00

abstract：:The layer-by-layer technique has been used as a powerful method to produce multilayer thin films with tunable properties. When natural polymers are employed, complicated phenomena such as self-aggregation and fibrilogenesis can occur, making it more difficult to obtain and characterize high-quality films. The weak aci...

journal_title：Biomacromolecules

authors： de Moraes MA,Crouzier T,Rubner M,Beppu MM

更新日期：2015-01-12 00:00:00

abstract：:Type I collagen is explored heavily for use in biomaterials, but the role of other extracellular matrix components in regulating collagen organization is gaining attention. We show that as the ratio of type III to type I collagen increases, fibril diameter decreases. A mixture of the two collagen types results in a mo...

journal_title：Biomacromolecules

authors： Stuart K,Panitch A

更新日期：2009-01-12 00:00:00